ES2158948T3 - Preparacion de purinas. - Google Patents
Preparacion de purinas.Info
- Publication number
- ES2158948T3 ES2158948T3 ES95921751T ES95921751T ES2158948T3 ES 2158948 T3 ES2158948 T3 ES 2158948T3 ES 95921751 T ES95921751 T ES 95921751T ES 95921751 T ES95921751 T ES 95921751T ES 2158948 T3 ES2158948 T3 ES 2158948T3
- Authority
- ES
- Spain
- Prior art keywords
- sub
- formula
- formula compound
- alcoxi
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001875 compounds Chemical class 0.000 abstract 10
- -1 HYDROXI Substances 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- 239000000460 chlorine Substances 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical group ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 abstract 1
- DUAJIKVIRGATIW-UHFFFAOYSA-N trinitrogen(.) Chemical class [N]=[N+]=[N-] DUAJIKVIRGATIW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Chemical Treatment Of Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9407698A GB9407698D0 (en) | 1994-04-19 | 1994-04-19 | Pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2158948T3 true ES2158948T3 (es) | 2001-09-16 |
Family
ID=10753741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES95921751T Expired - Lifetime ES2158948T3 (es) | 1994-04-19 | 1995-04-19 | Preparacion de purinas. |
Country Status (39)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9615276D0 (en) * | 1996-07-20 | 1996-09-04 | Smithkline Beecham Plc | Pharmaceuticals |
| GB9615253D0 (en) * | 1996-07-20 | 1996-09-04 | Smithkline Beecham Plc | Pharmaceuticals |
| GB9807116D0 (en) | 1998-04-02 | 1998-06-03 | Smithkline Beecham Plc | Novel process |
| GB9807114D0 (en) * | 1998-04-02 | 1998-06-03 | Smithkline Beecham Plc | Novel process |
| CA2496684A1 (en) * | 2002-08-26 | 2004-03-04 | Teva Pharmaceutical Industries Ltd | Crystalline solid famciclovir forms i, ii, iii and preparation thereof |
| TW200510415A (en) * | 2003-04-30 | 2005-03-16 | Teva Pharma | Process for the preparation of famciclovir |
| WO2005026167A1 (en) * | 2003-09-04 | 2005-03-24 | Teva Pharmaceutical Industries Ltd. | Process for preparing famciclovir |
| US7458839B2 (en) * | 2006-02-21 | 2008-12-02 | Fci Americas Technology, Inc. | Electrical connectors having power contacts with alignment and/or restraining features |
| US20050215787A1 (en) * | 2004-03-26 | 2005-09-29 | Joshi Ramesh A | An improved process for the preparation of purines |
| CN101072777A (zh) * | 2004-05-18 | 2007-11-14 | 特瓦制药工业有限公司 | 用于制备结晶固体泛昔洛韦的干燥方法 |
| GB2426247A (en) | 2005-05-20 | 2006-11-22 | Arrow Int Ltd | Methods of preparing purine derivatives such as famciclovir |
| CN102070636B (zh) * | 2011-01-17 | 2012-05-23 | 浙江大学 | 喷昔洛韦的制备方法 |
| CN104086552B (zh) * | 2014-07-31 | 2016-01-13 | 济南兆康医药科技有限公司 | 一种喷昔洛韦的精制方法 |
| CN104496991A (zh) * | 2014-11-04 | 2015-04-08 | 常州康丽制药有限公司 | 高品质2-氨基-6-氯-9-(4-羟基-3–羟甲基丁基)嘌呤的制备方法 |
| CN104744472A (zh) * | 2015-03-12 | 2015-07-01 | 常州康丽制药有限公司 | 高品质2-氨基-6-氯-9-(4-羟基-3-羟甲基丁基)嘌呤的制备方法 |
| CN108314685B (zh) * | 2018-03-16 | 2020-08-25 | 上药康丽（常州）药业有限公司 | 一种2-氨基-6-氯-9-(4-乙酰氧基-3-乙酰氧甲基丁基)嘌呤的制备方法 |
| CN110713490A (zh) * | 2018-07-12 | 2020-01-21 | 浙江医药股份有限公司新昌制药厂 | 一种喷昔洛韦的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH20807A (en) * | 1982-10-14 | 1987-04-21 | Wellcome Found | 2-amino-9-(2-hydroxyethoxymethyl)-9h-purine and salts thereof,their pharmaceutical formulations and their use |
| EP0141927B1 (en) * | 1983-08-18 | 1991-10-30 | Beecham Group Plc | Antiviral guanine derivatives |
| EP0182024B1 (en) * | 1984-09-20 | 1991-04-03 | Beecham Group Plc | Purine derivatives and their pharmaceutical use |
| US5175268A (en) * | 1986-12-24 | 1992-12-29 | Takeda Chemical Industries, Ltd. | DNA encoding recombinant human lymphotoxin |
| ES2098219T3 (es) * | 1987-08-01 | 1997-05-01 | Beecham Group Plc | Compuestos de purina y su preparacion. |
| GB8817607D0 (en) * | 1988-07-23 | 1988-09-01 | Beecham Group Plc | Novel process |
| GB8822236D0 (en) * | 1988-09-21 | 1988-10-26 | Beecham Group Plc | Chemical process |
| GB8922076D0 (en) * | 1989-09-28 | 1989-11-15 | Beecham Group Plc | Novel process |
-
1994
- 1994-04-19 GB GB9407698A patent/GB9407698D0/en active Pending
-
1995
- 1995-04-12 DZ DZ950040A patent/DZ1872A1/fr active
- 1995-04-13 AP APAP/P/1995/000730A patent/AP582A/en active
- 1995-04-17 MY MYPI95000990A patent/MY128846A/en unknown
- 1995-04-17 TW TW084103750A patent/TW311138B/zh not_active IP Right Cessation
- 1995-04-17 MA MA23846A patent/MA23518A1/fr unknown
- 1995-04-18 IN IN705DE1995 patent/IN183830B/en unknown
- 1995-04-18 IL IL11340995A patent/IL113409A/xx not_active IP Right Cessation
- 1995-04-18 ZA ZA953110A patent/ZA953110B/xx unknown
- 1995-04-19 DK DK95921751T patent/DK0756597T3/da active
- 1995-04-19 EG EG32695A patent/EG20938A/xx active
- 1995-04-19 ES ES95921751T patent/ES2158948T3/es not_active Expired - Lifetime
- 1995-04-19 SK SK1332-96A patent/SK283193B6/sk not_active IP Right Cessation
- 1995-04-19 CA CA002188181A patent/CA2188181C/en not_active Expired - Lifetime
- 1995-04-19 RU RU96121936/04A patent/RU2158266C2/ru active
- 1995-04-19 PT PT95921751T patent/PT756597E/pt unknown
- 1995-04-19 AT AT95921751T patent/ATE201209T1/de active
- 1995-04-19 EP EP95921751A patent/EP0756597B1/en not_active Expired - Lifetime
- 1995-04-19 DE DE69520945T patent/DE69520945T2/de not_active Expired - Lifetime
- 1995-04-19 AU AU26706/95A patent/AU691000B2/en not_active Expired
- 1995-04-19 CZ CZ19963053A patent/CZ287674B6/cs not_active IP Right Cessation
- 1995-04-19 HU HU9602891A patent/HU226209B1/hu unknown
- 1995-04-19 NZ NZ287858A patent/NZ287858A/en not_active IP Right Cessation
- 1995-04-19 WO PCT/EP1995/001840 patent/WO1995028402A2/en not_active Ceased
- 1995-04-19 AP APAP/P/1996/000870A patent/AP703A/en active
- 1995-04-19 MX MX9604942A patent/MX9604942A/es active IP Right Grant
- 1995-04-19 CN CN95193489A patent/CN1045963C/zh not_active Expired - Lifetime
- 1995-04-19 JP JP52673895A patent/JP3936734B2/ja not_active Expired - Lifetime
- 1995-04-19 UA UA96103899A patent/UA47401C2/uk unknown
- 1995-04-19 BR BR9507494A patent/BR9507494A/pt unknown
- 1995-04-19 PL PL95316943A patent/PL181219B1/pl unknown
- 1995-04-19 KR KR1019960705948A patent/KR100327147B1/ko not_active Expired - Lifetime
- 1995-04-19 RO RO96-02001A patent/RO118950B1/ro unknown
- 1995-04-26 SA SA95150619A patent/SA95150619B1/ar unknown
-
1996
- 1996-10-15 NO NO19964395A patent/NO315000B1/no not_active IP Right Cessation
- 1996-10-18 OA OA60905A patent/OA10376A/en unknown
- 1996-10-18 FI FI964193A patent/FI119691B/fi not_active IP Right Cessation
- 1996-10-18 BG BG100926A patent/BG63464B1/bg unknown
-
1999
- 1999-03-11 US US09/265,926 patent/US6846927B1/en not_active Expired - Fee Related
-
2001
- 2001-08-07 GR GR20010401190T patent/GR3036338T3/el unknown
-
2004
- 2004-12-14 US US11/011,352 patent/US7355043B2/en not_active Expired - Fee Related
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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