ES2061471T3 - Derivados de la piridina, compuestos farmaceuticos que comprenden la misma, su utilizacion para la fabricacion de medicamentos con valor terapeutico o preventivo y procedimiento para su fabricacion. - Google Patents

Derivados de la piridina, compuestos farmaceuticos que comprenden la misma, su utilizacion para la fabricacion de medicamentos con valor terapeutico o preventivo y procedimiento para su fabricacion.

Info

Publication number
ES2061471T3
ES2061471T3 ES87116797T ES87116797T ES2061471T3 ES 2061471 T3 ES2061471 T3 ES 2061471T3 ES 87116797 T ES87116797 T ES 87116797T ES 87116797 T ES87116797 T ES 87116797T ES 2061471 T3 ES2061471 T3 ES 2061471T3
Authority
ES
Spain
Prior art keywords
group
stands
manufacture
derivatives
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87116797T
Other languages
English (en)
Other versions
ES2061471T5 (es
Inventor
Shigeru Souda
Norihiro Mezon Gakuen Ueda
Shuhei Miyazawa
Katsuya Tagami
Seiichiro Nomoto
Makoto Okita
Naoyuki Shimomura
Toshihiko Sejuru Kasuga Kaneko
Masatoshi Fujimoto
Manabu Murakami
Kiyoshi Oketani
Hideaki Fujisaki
Hisashi Shibata
Tsuneo Wakabayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27283658&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2061471(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES2061471T3 publication Critical patent/ES2061471T3/es
Application granted granted Critical
Publication of ES2061471T5 publication Critical patent/ES2061471T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA DERIVADOS DE PIRIDINA Y SALES FARMACEUTICAMENTE ACEPTABLES DE ELLOS DE FORMULA GENERAL (I) EN LA QUE R1 Y R2 QUE PUEDEN SER IGUALES O DIFERENTES REPRESENTAN UN ATOMO DE HIDROGENO O DE HALOGENO O UN GRUPO ALQUILO, ALCOXI, ALQUILO HALOGENADO, ALCOXICARBONILO O CARBOXILO; X REPRESENTA UN GRUPO DE FORMULA (II) ( EN EL QUE R3 ES H O UN GRUPO ALQUILO, FENILO, BENCILO O ALCOXICARBONILO); Z ES UN GRUPO DE UNA SERIE DE ELLOS ESPECIFICADOS EN LA INVENCION; J Y K QUE PUEDEN SER IGUALES O DIFERENTES REPRESENTAN CADA UNO UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO DE CADENA CORTA. TAMBIEN SE REFIERE LA INVENCION A COMPOSICIONES FARMACEUTICAS QUE CONTIENEN LOS INDICADOS DERIVADOS, A SU EMPLEO EN LA PREPARACION DE MEDICAMENTOS DE VALOR TERAPEUTICO O PREVENTIVO PARA EL TRATAMIENTO DE ULCERAS PEPTICAS Y A PROCESOS PARA SU PREPARACION.
ES87116797T 1986-11-13 1987-11-13 Derivados de la piridina, compuestos farmaceuticos que comprenden la misma, su utilizacion para la fabricacion de medicamentos con valor terapeutico o preventivo y procedimiento para su fabricacion. Expired - Lifetime ES2061471T5 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP27053686 1986-11-13
JP2198987 1987-02-02
JP7778487 1987-03-31

Publications (2)

Publication Number Publication Date
ES2061471T3 true ES2061471T3 (es) 1994-12-16
ES2061471T5 ES2061471T5 (es) 1998-07-16

Family

ID=27283658

Family Applications (3)

Application Number Title Priority Date Filing Date
ES87116797T Expired - Lifetime ES2061471T5 (es) 1986-11-13 1987-11-13 Derivados de la piridina, compuestos farmaceuticos que comprenden la misma, su utilizacion para la fabricacion de medicamentos con valor terapeutico o preventivo y procedimiento para su fabricacion.
ES95102165T Expired - Lifetime ES2118457T3 (es) 1986-11-13 1987-11-13 Derivados de piridina, composiciones farmaceuticas que comprenden los mismos, el uso de los mismos para la fabricacion de medicamentos que tienen valor terapeutico o preventivo, y un proceso para preparar los mismos.
ES91117132T Expired - Lifetime ES2112260T3 (es) 1986-11-13 1987-11-13 Derivados de piridina, composiciones farmaceuticas que comprenden los mismos, su utilizacion en la fabricacion de medicamentos que tienen valor terapeutico o preventivo y procedimiento para su fabricacion.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES95102165T Expired - Lifetime ES2118457T3 (es) 1986-11-13 1987-11-13 Derivados de piridina, composiciones farmaceuticas que comprenden los mismos, el uso de los mismos para la fabricacion de medicamentos que tienen valor terapeutico o preventivo, y un proceso para preparar los mismos.
ES91117132T Expired - Lifetime ES2112260T3 (es) 1986-11-13 1987-11-13 Derivados de piridina, composiciones farmaceuticas que comprenden los mismos, su utilizacion en la fabricacion de medicamentos que tienen valor terapeutico o preventivo y procedimiento para su fabricacion.

Country Status (18)

Country Link
US (3) US5045552A (es)
EP (3) EP0475456B1 (es)
JP (1) JP2544567B2 (es)
KR (1) KR910003330B1 (es)
CN (1) CN1018923B (es)
AT (2) ATE163011T1 (es)
AU (1) AU594836B2 (es)
CA (1) CA1265138A (es)
DE (4) DE3752167T2 (es)
DK (2) DK171024B1 (es)
ES (3) ES2061471T5 (es)
FI (1) FI90544C (es)
HK (1) HK194296A (es)
HU (1) HU198475B (es)
LU (1) LU90396I2 (es)
NL (1) NL990015I2 (es)
NO (2) NO170932C (es)
NZ (1) NZ222488A (es)

Families Citing this family (152)

* Cited by examiner, † Cited by third party
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