ES8704477A1 - Procedimiento para preparar piridin-1-oxidos varias veces substituidos - Google Patents

Procedimiento para preparar piridin-1-oxidos varias veces substituidos

Info

Publication number
ES8704477A1
ES8704477A1 ES554054A ES554054A ES8704477A1 ES 8704477 A1 ES8704477 A1 ES 8704477A1 ES 554054 A ES554054 A ES 554054A ES 554054 A ES554054 A ES 554054A ES 8704477 A1 ES8704477 A1 ES 8704477A1
Authority
ES
Spain
Prior art keywords
atoms
group
multiply
oxides
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554054A
Other languages
English (en)
Other versions
ES554054A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES8704477A1 publication Critical patent/ES8704477A1/es
Publication of ES554054A0 publication Critical patent/ES554054A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR PIRIDIN-1-OXIDOS SUSTITUIDOS. COMPRENDE: A) OXIDAR A UN COMPUESTO DE FORMULA (II) CON PERACETICO O PERBENZOICO, EN TOLUENO OXILENO, ENTRE 10JC Y 70JC, PARA PRODUCIR UN COMPUESTO DE FORMULA (III); Y B) TRATAR A (III) CON UN COMPUESTO DE FORMULA (HNR3R4), EN ETANOL O DIOXANO EN PRESENCIA DE CARBONATO DE ALCALINO, ENTRE 0JC Y 100JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FISIOLOGICAMENTE COMPATIBLES. SIENDO: X, CIANO O NITRO O EL GRUPO -CO-R5; R1 Y R2 IGUALES O DISTINTOS, ALQUILO DE C 1 A 6; R3, H; R4, MERCAPROALQUILO DE C 4; R5, AMINO Y Z, HAL. SE UTILIZAN COMO ANTIAMNESICOS.
ES554054A 1985-04-18 1986-04-16 Procedimiento para preparar piridin-1-oxidos varias veces substituidos Expired ES8704477A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853514073 DE3514073A1 (de) 1985-04-18 1985-04-18 Mehrfach substituierte pyridin-1-oxide, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung

Publications (2)

Publication Number Publication Date
ES8704477A1 true ES8704477A1 (es) 1987-04-01
ES554054A0 ES554054A0 (es) 1987-04-01

Family

ID=6268515

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554054A Expired ES8704477A1 (es) 1985-04-18 1986-04-16 Procedimiento para preparar piridin-1-oxidos varias veces substituidos

Country Status (19)

Country Link
US (1) US4859663A (es)
EP (1) EP0250436B1 (es)
JP (1) JPS62502751A (es)
KR (1) KR870700605A (es)
AT (1) ATE47995T1 (es)
AU (1) AU586255B2 (es)
DE (2) DE3514073A1 (es)
DK (1) DK157924C (es)
ES (1) ES8704477A1 (es)
FI (1) FI874549A0 (es)
GR (1) GR861002B (es)
HU (1) HU199123B (es)
IL (1) IL78521A (es)
NO (1) NO865131L (es)
NZ (1) NZ215852A (es)
PH (1) PH23308A (es)
PT (1) PT82416B (es)
WO (1) WO1986006067A1 (es)
ZA (1) ZA862875B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008818D0 (en) * 1990-04-19 1990-06-13 Ici Plc Amine derivatives
TW200462B (es) * 1990-09-27 1993-02-21 Hoechst Roussel Pharma

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6604123A (es) * 1965-05-28 1966-11-29
US3547935A (en) * 1967-08-07 1970-12-15 American Cyanamid Co Certain nitro-4-pyridinols,n-oxides thereof and derivatives thereof
US3495969A (en) * 1967-09-25 1970-02-17 Mobil Oil Corp Substituted nitropyridines as herbicides
BE786565A (fr) * 1971-07-23 1973-01-22 Upjohn Co Nouveaux oxydes de pyridine substitues et leur preparation
GB1542605A (en) * 1977-02-22 1979-03-21 Bristol Myers Co 4-tertiary-amino-2,6-diaminopyridine-1-oxides
DE2708058A1 (de) * 1977-02-24 1978-08-31 Bristol Myers Co Pyridin-1-oxide, verfahren zu ihrer herstellung und daraus hergestellte arzneimittel
DE2900504A1 (de) * 1979-01-08 1980-07-24 Hoechst Ag Neue substituierte 4-aminopyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0250436A1 (de) 1988-01-07
US4859663A (en) 1989-08-22
NZ215852A (en) 1989-01-06
GR861002B (en) 1986-08-04
FI874549A (fi) 1987-10-15
IL78521A0 (en) 1986-08-31
IL78521A (en) 1989-09-10
KR870700605A (ko) 1987-12-30
ZA862875B (en) 1986-12-30
PT82416B (pt) 1988-08-17
AU586255B2 (en) 1989-07-06
PT82416A (de) 1986-05-01
ATE47995T1 (de) 1989-12-15
HUT47910A (en) 1989-04-28
HU199123B (en) 1990-01-29
DE3514073A1 (de) 1986-10-23
DK157924C (da) 1990-08-27
DK608586A (da) 1986-12-17
DE3666951D1 (en) 1989-12-21
DK608586D0 (da) 1986-12-17
NO865131L (no) 1986-12-17
AU5814386A (en) 1986-11-05
JPS62502751A (ja) 1987-10-22
EP0250436B1 (de) 1989-11-15
DK157924B (da) 1990-03-05
WO1986006067A1 (en) 1986-10-23
ES554054A0 (es) 1987-04-01
FI874549A0 (fi) 1987-10-15
PH23308A (en) 1989-06-30

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401