EP0964677A4 - Verzögerter analgesie erreicht mit buprenorphin - Google Patents

Verzögerter analgesie erreicht mit buprenorphin

Info

Publication number
EP0964677A4
EP0964677A4 EP98906678A EP98906678A EP0964677A4 EP 0964677 A4 EP0964677 A4 EP 0964677A4 EP 98906678 A EP98906678 A EP 98906678A EP 98906678 A EP98906678 A EP 98906678A EP 0964677 A4 EP0964677 A4 EP 0964677A4
Authority
EP
European Patent Office
Prior art keywords
buprenorphine
sustained analgesia
provides
analgesia achieved
over
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP98906678A
Other languages
English (en)
French (fr)
Other versions
EP0964677B1 (de
EP0964677A1 (de
Inventor
Robert F Reder
Paul D Goldenheim
Robert F Kaiko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26715643&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0964677(A4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to SI9830859T priority Critical patent/SI0964677T1/sl
Priority to DK06118876.9T priority patent/DK1731152T3/da
Priority to EP10185233A priority patent/EP2305192A1/de
Priority to DK05011213.5T priority patent/DK1570823T3/da
Priority to EP06118876.9A priority patent/EP1731152B1/de
Priority to EP10185237A priority patent/EP2305193A1/de
Priority to EP05011213A priority patent/EP1570823B1/de
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Priority to EP10185240A priority patent/EP2305194B1/de
Priority to EP10185241A priority patent/EP2301494A1/de
Priority to EP10185235A priority patent/EP2301493A1/de
Priority to EP10185230A priority patent/EP2305191A1/de
Publication of EP0964677A1 publication Critical patent/EP0964677A1/de
Publication of EP0964677A4 publication Critical patent/EP0964677A4/de
Publication of EP0964677B1 publication Critical patent/EP0964677B1/de
Application granted granted Critical
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Saccharide Compounds (AREA)
EP98906678A 1997-02-24 1998-02-24 Verzögerte analgesie erreicht mit transdermaler verabreichung von buprenorphin Revoked EP0964677B1 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
EP10185240A EP2305194B1 (de) 1997-02-24 1998-02-24 Transdermales Pflaster mit Buprenorphin zur Verwendung in der Behandlung von Schmerzen für ein Dosierung-Intervall von 7 Tagen
EP10185233A EP2305192A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
DK05011213.5T DK1570823T3 (da) 1997-02-24 1998-02-24 Transdermalt plaster med buprenorphin til anvendelse i behandling af smerter til et doseringsinterval på mindst 4 dage
EP06118876.9A EP1731152B1 (de) 1997-02-24 1998-02-24 Verzögerte Analgesie erreicht mit transdermaler Verabreichung von Buprenorphin
EP10185237A EP2305193A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP05011213A EP1570823B1 (de) 1997-02-24 1998-02-24 Transdermales Pflaster mit Buprenorphin zur Verwendung in der Behandlung von Schmerzen für ein Dosierung-Intervall von mindestens 4 Tagen
SI9830859T SI0964677T1 (sl) 1997-02-24 1998-02-24 Podaljsana analgezija, dosezena s transdermalnim dajanjem buprenorfina
EP10185241A EP2301494A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP10185235A EP2301493A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
DK06118876.9T DK1731152T3 (da) 1997-02-24 1998-02-24 Vedvarende analgetika opnået ved transdermal tilførsel af buprenorphin
EP10185230A EP2305191A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3891997P 1997-02-24 1997-02-24
US38919P 1997-02-24
US08/939,068 US5968547A (en) 1997-02-24 1997-09-29 Method of providing sustained analgesia with buprenorphine
US939068 1997-09-29
PCT/US1998/003584 WO1998036728A2 (en) 1997-02-24 1998-02-24 Sustained analgesia achieved with buprenorphine

Related Child Applications (3)

Application Number Title Priority Date Filing Date
EP06118876.9A Division EP1731152B1 (de) 1997-02-24 1998-02-24 Verzögerte Analgesie erreicht mit transdermaler Verabreichung von Buprenorphin
EP05011213A Division EP1570823B1 (de) 1997-02-24 1998-02-24 Transdermales Pflaster mit Buprenorphin zur Verwendung in der Behandlung von Schmerzen für ein Dosierung-Intervall von mindestens 4 Tagen
EP05011213.5 Division-Into 2005-05-24

Publications (3)

Publication Number Publication Date
EP0964677A1 EP0964677A1 (de) 1999-12-22
EP0964677A4 true EP0964677A4 (de) 2002-12-18
EP0964677B1 EP0964677B1 (de) 2006-08-16

Family

ID=26715643

Family Applications (9)

Application Number Title Priority Date Filing Date
EP10185235A Withdrawn EP2301493A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP10185233A Withdrawn EP2305192A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP10185240A Revoked EP2305194B1 (de) 1997-02-24 1998-02-24 Transdermales Pflaster mit Buprenorphin zur Verwendung in der Behandlung von Schmerzen für ein Dosierung-Intervall von 7 Tagen
EP10185230A Withdrawn EP2305191A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP10185241A Withdrawn EP2301494A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP06118876.9A Revoked EP1731152B1 (de) 1997-02-24 1998-02-24 Verzögerte Analgesie erreicht mit transdermaler Verabreichung von Buprenorphin
EP05011213A Revoked EP1570823B1 (de) 1997-02-24 1998-02-24 Transdermales Pflaster mit Buprenorphin zur Verwendung in der Behandlung von Schmerzen für ein Dosierung-Intervall von mindestens 4 Tagen
EP98906678A Revoked EP0964677B1 (de) 1997-02-24 1998-02-24 Verzögerte analgesie erreicht mit transdermaler verabreichung von buprenorphin
EP10185237A Withdrawn EP2305193A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin

Family Applications Before (7)

Application Number Title Priority Date Filing Date
EP10185235A Withdrawn EP2301493A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP10185233A Withdrawn EP2305192A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP10185240A Revoked EP2305194B1 (de) 1997-02-24 1998-02-24 Transdermales Pflaster mit Buprenorphin zur Verwendung in der Behandlung von Schmerzen für ein Dosierung-Intervall von 7 Tagen
EP10185230A Withdrawn EP2305191A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP10185241A Withdrawn EP2301494A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin
EP06118876.9A Revoked EP1731152B1 (de) 1997-02-24 1998-02-24 Verzögerte Analgesie erreicht mit transdermaler Verabreichung von Buprenorphin
EP05011213A Revoked EP1570823B1 (de) 1997-02-24 1998-02-24 Transdermales Pflaster mit Buprenorphin zur Verwendung in der Behandlung von Schmerzen für ein Dosierung-Intervall von mindestens 4 Tagen

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP10185237A Withdrawn EP2305193A1 (de) 1997-02-24 1998-02-24 Analgetisch Wirksame Zusammensetzung mit verzögerter Wirkstoffabgabe von Buprenorphin

Country Status (21)

Country Link
US (15) US5968547A (de)
EP (9) EP2301493A1 (de)
JP (1) JP2000511936A (de)
KR (1) KR100703101B1 (de)
CN (2) CN1827107B (de)
AT (3) ATE336212T1 (de)
AU (2) AU2004218685B2 (de)
BR (1) BR9815439A (de)
CA (1) CA2276170C (de)
CZ (2) CZ299414B6 (de)
DE (2) DE05011213T1 (de)
DK (4) DK2305194T3 (de)
ES (4) ES2380023T3 (de)
HU (3) HU230608B1 (de)
IL (4) IL131561A0 (de)
NO (11) NO322515B1 (de)
NZ (1) NZ337386A (de)
PL (1) PL196086B1 (de)
PT (4) PT1570823E (de)
SI (3) SI0964677T1 (de)
WO (1) WO1998036728A2 (de)

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