DK1864975T3 - Nikotinamid-derivater anvendelige som P38-inhibitorer - Google Patents
Nikotinamid-derivater anvendelige som P38-inhibitorerInfo
- Publication number
- DK1864975T3 DK1864975T3 DK07117575.6T DK07117575T DK1864975T3 DK 1864975 T3 DK1864975 T3 DK 1864975T3 DK 07117575 T DK07117575 T DK 07117575T DK 1864975 T3 DK1864975 T3 DK 1864975T3
- Authority
- DK
- Denmark
- Prior art keywords
- inhibitors
- derivatives useful
- nicotinamide derivatives
- kinase
- useful
- Prior art date
Links
- 239000012826 P38 inhibitor Substances 0.000 title 1
- 150000005480 nicotinamides Chemical class 0.000 title 1
- 102000002574 p38 Mitogen-Activated Protein Kinases Human genes 0.000 abstract 3
- 230000000694 effects Effects 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
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- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0203301.7A GB0203301D0 (en) | 2002-02-12 | 2002-02-12 | Novel compounds |
| GB0225385A GB0225385D0 (en) | 2002-10-31 | 2002-10-31 | Novel compounds |
| EP03704769A EP1474395B1 (en) | 2002-02-12 | 2003-02-10 | Nicotinamide derivates useful as p38 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1864975T3 true DK1864975T3 (da) | 2011-01-24 |
Family
ID=27736200
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07117575.6T DK1864975T3 (da) | 2002-02-12 | 2003-02-10 | Nikotinamid-derivater anvendelige som P38-inhibitorer |
| DK03704769T DK1474395T3 (da) | 2002-02-12 | 2003-02-10 | Nicotinamidderivater, der er nyttige som p38-inhibitorer |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03704769T DK1474395T3 (da) | 2002-02-12 | 2003-02-10 | Nicotinamidderivater, der er nyttige som p38-inhibitorer |
Country Status (25)
| Country | Link |
|---|---|
| US (5) | US7125898B2 (enExample) |
| EP (3) | EP1864975B1 (enExample) |
| JP (2) | JP4472349B2 (enExample) |
| KR (1) | KR101058292B1 (enExample) |
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-
2003
- 2003-02-10 SI SI200331928T patent/SI1864975T1/sl unknown
- 2003-02-10 SI SI200331042T patent/SI1474395T1/sl unknown
- 2003-02-10 EP EP07117575A patent/EP1864975B1/en not_active Expired - Lifetime
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- 2003-02-10 CN CNB038038064A patent/CN100369898C/zh not_active Expired - Lifetime
- 2003-02-10 ES ES10180693T patent/ES2400486T3/es not_active Expired - Lifetime
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- 2003-02-10 MX MXPA04007838A patent/MXPA04007838A/es active IP Right Grant
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- 2003-02-10 BR BRPI0307351A patent/BRPI0307351B8/pt not_active IP Right Cessation
- 2003-02-10 DK DK07117575.6T patent/DK1864975T3/da active
- 2003-02-10 EP EP10180693A patent/EP2258687B1/en not_active Expired - Lifetime
- 2003-02-10 DE DE60334651T patent/DE60334651D1/de not_active Expired - Lifetime
- 2003-02-10 PT PT07117575T patent/PT1864975E/pt unknown
- 2003-02-10 DE DE60316913T patent/DE60316913T2/de not_active Expired - Lifetime
- 2003-02-10 RU RU2004120553/04A patent/RU2309951C2/ru active
- 2003-02-10 PT PT03704769T patent/PT1474395E/pt unknown
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- 2003-02-10 WO PCT/GB2003/000554 patent/WO2003068747A1/en not_active Ceased
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- 2003-02-10 KR KR1020047012405A patent/KR101058292B1/ko not_active Expired - Lifetime
- 2003-02-10 AT AT07117575T patent/ATE485275T1/de active
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