ATE485275T1 - Nicotinamide und deren verwendung als p38 inhibitoren - Google Patents

Nicotinamide und deren verwendung als p38 inhibitoren

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Publication number
ATE485275T1
ATE485275T1 AT07117575T AT07117575T ATE485275T1 AT E485275 T1 ATE485275 T1 AT E485275T1 AT 07117575 T AT07117575 T AT 07117575T AT 07117575 T AT07117575 T AT 07117575T AT E485275 T1 ATE485275 T1 AT E485275T1
Authority
AT
Austria
Prior art keywords
inhibitors
nicotinamides
kinase
activity
mediated
Prior art date
Application number
AT07117575T
Other languages
English (en)
Inventor
Nicola Aston
Paul Bamborough
Ann Walker
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0203301.7A external-priority patent/GB0203301D0/en
Priority claimed from GB0225385A external-priority patent/GB0225385D0/en
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Application granted granted Critical
Publication of ATE485275T1 publication Critical patent/ATE485275T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
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AT07117575T 2002-02-12 2003-02-10 Nicotinamide und deren verwendung als p38 inhibitoren ATE485275T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0203301.7A GB0203301D0 (en) 2002-02-12 2002-02-12 Novel compounds
GB0225385A GB0225385D0 (en) 2002-10-31 2002-10-31 Novel compounds

Publications (1)

Publication Number Publication Date
ATE485275T1 true ATE485275T1 (de) 2010-11-15

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AT03704769T ATE375980T1 (de) 2002-02-12 2003-02-10 Nicotinamide und deren verwendung als p38 inhibitoren

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ES2400486T3 (es) 2013-04-10
EP2258687B1 (de) 2012-12-26
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BRPI0307351B8 (pt) 2021-05-25
US8575204B2 (en) 2013-11-05
US20100215652A1 (en) 2010-08-26
EP1474395A1 (de) 2004-11-10
CN1633416A (zh) 2005-06-29
US8252818B2 (en) 2012-08-28
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