DK175096B1 - Sulfonamid-forbindelser, farmaceutiske præparater indeholdende disse sulfonamidforbindelser til anvendelse som lægemidler og deres anvendelse til fremstilling af antiarytmiske midler samt forbindelser, der er anvendelige - Google Patents

Sulfonamid-forbindelser, farmaceutiske præparater indeholdende disse sulfonamidforbindelser til anvendelse som lægemidler og deres anvendelse til fremstilling af antiarytmiske midler samt forbindelser, der er anvendelige Download PDF

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Publication number
DK175096B1
DK175096B1 DK198702202A DK220287A DK175096B1 DK 175096 B1 DK175096 B1 DK 175096B1 DK 198702202 A DK198702202 A DK 198702202A DK 220287 A DK220287 A DK 220287A DK 175096 B1 DK175096 B1 DK 175096B1
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DK
Denmark
Prior art keywords
compounds
alkyl
alk
methyl
formula
Prior art date
Application number
DK198702202A
Other languages
Danish (da)
English (en)
Other versions
DK220287A (da
DK220287D0 (da
Inventor
Peter Edward Cross
John Edmund Arrowsmith
Geoffrey Noel Thomas
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26290703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK175096(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB868610668A external-priority patent/GB8610668D0/en
Priority claimed from GB868630059A external-priority patent/GB8630059D0/en
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of DK220287D0 publication Critical patent/DK220287D0/da
Publication of DK220287A publication Critical patent/DK220287A/da
Application granted granted Critical
Publication of DK175096B1 publication Critical patent/DK175096B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Lubricants (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyamides (AREA)
DK198702202A 1986-05-01 1987-04-30 Sulfonamid-forbindelser, farmaceutiske præparater indeholdende disse sulfonamidforbindelser til anvendelse som lægemidler og deres anvendelse til fremstilling af antiarytmiske midler samt forbindelser, der er anvendelige DK175096B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8610668 1986-05-01
GB868610668A GB8610668D0 (en) 1986-05-01 1986-05-01 Anti-arrhythmia agents
GB8630059 1986-12-17
GB868630059A GB8630059D0 (en) 1986-12-17 1986-12-17 Antiarrhythmic agents

Publications (3)

Publication Number Publication Date
DK220287D0 DK220287D0 (da) 1987-04-30
DK220287A DK220287A (da) 1987-11-02
DK175096B1 true DK175096B1 (da) 2004-06-01

Family

ID=26290703

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198702202A DK175096B1 (da) 1986-05-01 1987-04-30 Sulfonamid-forbindelser, farmaceutiske præparater indeholdende disse sulfonamidforbindelser til anvendelse som lægemidler og deres anvendelse til fremstilling af antiarytmiske midler samt forbindelser, der er anvendelige

Country Status (27)

Country Link
US (2) US4959366A (bs)
EP (1) EP0245997B1 (bs)
KR (2) KR870011084A (bs)
CN (1) CN1019801B (bs)
AT (1) ATE74906T1 (bs)
AU (1) AU578557B2 (bs)
BA (2) BA98211B1 (bs)
CA (1) CA1289140C (bs)
DE (2) DE10075004I2 (bs)
DK (1) DK175096B1 (bs)
EG (1) EG18188A (bs)
ES (1) ES2033840T3 (bs)
FI (1) FI88291C (bs)
GR (1) GR3004457T3 (bs)
HU (1) HU196743B (bs)
IE (1) IE59366B1 (bs)
IL (1) IL82373A (bs)
LU (1) LU90519I2 (bs)
LV (1) LV5715B4 (bs)
MY (1) MY111142A (bs)
NL (1) NL300002I2 (bs)
NO (2) NO168527C (bs)
NZ (1) NZ220151A (bs)
PH (1) PH23425A (bs)
PL (1) PL149924B1 (bs)
PT (1) PT84782B (bs)
YU (2) YU46195B (bs)

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AU4787593A (en) * 1992-07-31 1994-03-03 Syntex (U.S.A.) Inc. Heterocyclic derivatives useful in the treatment of cardiovascular diseases
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
GB9404485D0 (en) * 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
DE4422517A1 (de) * 1994-06-28 1996-01-04 Dresden Arzneimittel Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE69531691T2 (de) * 1994-08-04 2004-07-08 C & C Research Labs Neues amin-derivat, verfahren zur herstellung und dessen verwendung als anti-arrhythmisches mittel
EP0697407B1 (en) 1994-08-19 1997-06-25 MITSUI TOATSU CHEMICALS, Inc. Pyrimidinedione derivatives and antiarrhythmic compositions containing same
US5679706A (en) * 1994-09-30 1997-10-21 Bristol-Myers Squibb Company Combination of a potassium channel activator and an antiarrhythmic agent
FR2726267B1 (fr) * 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
CN1055679C (zh) * 1995-12-06 2000-08-23 中国药科大学 具有心血管活性的苯乙胺衍生物
CN1055682C (zh) * 1995-12-06 2000-08-23 中国药科大学 甲磺酰胺基苯乙胺衍生物的新制备方法
GB9722662D0 (en) * 1997-10-27 1997-12-24 Pfizer Ltd Polymorphs
HUP9702411A2 (hu) * 1997-12-11 2000-03-28 Gyógyszerkutató Intézet Kft. Fenoxi-alkil-amin-származékok és a vegyületeket tartalmazó antiaritmiás hatású gyógyszerkészítmények
US7375136B2 (en) * 2001-03-08 2008-05-20 Emory University pH-dependent NMDA receptor antagonists
CN100358865C (zh) * 2001-07-30 2008-01-02 中国科学院上海药物研究所 一类磺酰胺苯烷胺类化合物及其制备方法和用途
DE10201550A1 (de) * 2002-01-17 2003-07-31 Merck Patent Gmbh Phenoxy-Piperidine
AU2002357560A1 (en) * 2002-04-26 2003-11-10 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Sulfamidophenylalkylamines and their production and use
EP2332921B1 (en) * 2003-06-17 2016-03-02 Arena Pharmaceuticals, Inc. 8-Chloro-1 -methyl-2,3,4,5-tetrahydro-1 H-3benzazapine Hydrochloride
EP1633720A1 (en) * 2003-06-17 2006-03-15 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases
DE102004025726B4 (de) * 2004-05-26 2006-07-06 Roder, Hanno, Dr. Verwendung eines spezifischen K252a-Derivats zur Verhinderung oder Behandlung der Alzheimerschen Krankheit
CA2672650C (en) * 2006-12-14 2015-09-08 Tautatis, Inc. Compositions and methods for the treatment of cancer
AU2008272964A1 (en) 2007-06-29 2009-01-08 Emory University NMDA receptor antagonists for neuroprotection
CN101372467B (zh) * 2007-08-23 2011-09-14 明德国际仓储贸易(上海)有限公司 具有n,n-二烷氨基的桥基化合物及所应用的染料化合物
EP2288585A1 (en) 2008-03-04 2011-03-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
CN102648170A (zh) 2009-06-18 2012-08-22 艾尼纳制药公司 制备5-ht2c受体激动剂的方法
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
EA201390335A1 (ru) 2010-09-01 2013-09-30 Арена Фармасьютикалз, Инк. Введение лоркасерина индивидуумам с почечной недостаточностью
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
CN102531946A (zh) * 2012-01-05 2012-07-04 山东大学 3-甲氧基苯甲酰胺衍生物及其制备方法与应用
AU2012392187B2 (en) 2012-10-09 2018-07-12 Arena Pharmaceuticals, Inc. Method of weight management
FR3029113A1 (fr) 2014-12-02 2016-06-03 Univ Paris-Sud Composes pour le traitement des maladies mitochondriales
CZ307826B6 (cs) * 2017-12-01 2019-05-29 Farmak, A.S. Způsob přípravy N-[4-(2-{[2-(4-methansulfonamidofenoxy)ethyl](methyl)amino}ethyl)fenyl]methansulfonamidu (Dofetilidu)
US10888524B2 (en) 2018-02-05 2021-01-12 Enaltec Pharma Research Pvt. Ltd. Immediate release tablet of dofetilide

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FR977261A (fr) * 1948-11-04 1951-03-29 équilibrage des masses dans les moteurs à combustion interne
US3478149A (en) * 1962-01-24 1969-11-11 Mead Johnson & Co Therapeutic compositions and methods employing sulfonamidophenethanolamines
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CA1120058A (en) * 1978-07-03 1982-03-16 Jack Mills Phenethanolamines, formulations and potentiation of oncolytic drugs
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Also Published As

Publication number Publication date
ES2033840T3 (es) 1993-04-01
PL149924B1 (en) 1990-04-30
DK220287A (da) 1987-11-02
CN1019801B (zh) 1992-12-30
BA98301A (bs) 2001-09-14
HU196743B (en) 1989-01-30
KR920014397A (ko) 1992-07-30
PL265418A1 (en) 1988-07-21
IE871165L (en) 1987-11-01
FI871898A (fi) 1987-11-02
AU7226087A (en) 1987-11-19
HUT43558A (en) 1987-11-30
FI88291B (fi) 1993-01-15
NO871820D0 (no) 1987-04-30
IL82373A0 (en) 1987-10-30
DK220287D0 (da) 1987-04-30
YU73588A (en) 1990-04-30
FI871898A0 (fi) 1987-04-29
BA98211B1 (bs) 1999-08-02
KR870011084A (ko) 1987-12-19
US4959366A (en) 1990-09-25
DE10075004I2 (de) 2006-02-02
IE59366B1 (en) 1994-02-09
GR3004457T3 (bs) 1993-03-31
NL300002I2 (nl) 2000-05-01
CN87103300A (zh) 1987-11-11
LV5715B4 (lv) 1996-02-20
LV5715A4 (lv) 1995-10-20
KR930001339B1 (ko) 1993-02-26
EP0245997A2 (en) 1987-11-19
NO168527B (no) 1991-11-25
MY111142A (en) 1999-09-30
IL82373A (en) 1992-01-15
NZ220151A (en) 1989-02-24
CA1289140C (en) 1991-09-17
NO871820L (no) 1987-11-02
DE10075004I1 (de) 2000-04-13
LU90519I2 (fr) 2000-04-10
FI88291C (fi) 1993-04-26
DE3778201D1 (de) 1992-05-21
ATE74906T1 (de) 1992-05-15
NO168527C (no) 1992-03-04
YU78387A (en) 1988-08-31
US5079248A (en) 1992-01-07
AU578557B2 (en) 1988-10-27
YU46195B (sh) 1993-05-28
EP0245997A3 (en) 1989-12-20
EG18188A (en) 1992-09-30
PT84782A (en) 1987-05-01
PT84782B (pt) 1989-12-29
YU46541B (sh) 1993-11-16
PH23425A (en) 1989-08-07
NO2001011I1 (no) 2001-07-16
EP0245997B1 (en) 1992-04-15
NL300002I1 (nl) 2000-04-03

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Free format text: PRODUCT NAME: DOFETILID

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