BA98211B1 - Postupak za dobijanje antiaritmickih agenasa - Google Patents

Postupak za dobijanje antiaritmickih agenasa

Info

Publication number
BA98211B1
BA98211B1 BA980211A BA980211A BA98211B1 BA 98211 B1 BA98211 B1 BA 98211B1 BA 980211 A BA980211 A BA 980211A BA 980211 A BA980211 A BA 980211A BA 98211 B1 BA98211 B1 BA 98211B1
Authority
BA
Bosnia and Herzegovina
Prior art keywords
alkyl
group
formula
compounds
antiarrhythmic agents
Prior art date
Application number
BA980211A
Other languages
English (en)
Inventor
John Edmund Arrowsmith
Peter Edward Cross
Geoffrey Noel Thomas
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26290703&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BA98211(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB868610668A external-priority patent/GB8610668D0/en
Priority claimed from GB868630059A external-priority patent/GB8630059D0/en
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Priority to BA980301A priority Critical patent/BA98301A/bs
Application granted granted Critical
Publication of BA98211B1 publication Critical patent/BA98211B1/bs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
  • Polyamides (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cephalosporin Compounds (AREA)
  • Lubricants (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Plural Heterocyclic Compounds (AREA)
BA980211A 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa BA98211B1 (bs)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BA980301A BA98301A (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB868610668A GB8610668D0 (en) 1986-05-01 1986-05-01 Anti-arrhythmia agents
GB868630059A GB8630059D0 (en) 1986-12-17 1986-12-17 Antiarrhythmic agents
YU78387A YU46195B (sh) 1986-05-01 1987-04-30 Postupak za dobijanje antiaritmičkih agenasa

Publications (1)

Publication Number Publication Date
BA98211B1 true BA98211B1 (bs) 1999-08-02

Family

ID=26290703

Family Applications (2)

Application Number Title Priority Date Filing Date
BA980301A BA98301A (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa
BA980211A BA98211B1 (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BA980301A BA98301A (bs) 1986-05-01 1998-03-30 Postupak za dobijanje antiaritmickih agenasa

Country Status (27)

Country Link
US (2) US4959366A (bs)
EP (1) EP0245997B1 (bs)
KR (2) KR870011084A (bs)
CN (1) CN1019801B (bs)
AT (1) ATE74906T1 (bs)
AU (1) AU578557B2 (bs)
BA (2) BA98301A (bs)
CA (1) CA1289140C (bs)
DE (2) DE3778201D1 (bs)
DK (1) DK175096B1 (bs)
EG (1) EG18188A (bs)
ES (1) ES2033840T3 (bs)
FI (1) FI88291C (bs)
GR (1) GR3004457T3 (bs)
HU (1) HU196743B (bs)
IE (1) IE59366B1 (bs)
IL (1) IL82373A (bs)
LU (1) LU90519I2 (bs)
LV (1) LV5715B4 (bs)
MY (1) MY111142A (bs)
NL (1) NL300002I2 (bs)
NO (2) NO168527C (bs)
NZ (1) NZ220151A (bs)
PH (1) PH23425A (bs)
PL (1) PL149924B1 (bs)
PT (1) PT84782B (bs)
YU (2) YU46195B (bs)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602174A (en) * 1986-02-15 1997-02-11 Beecham Wuefling Gmbh & Co. Treatment
NL8700842A (bs) * 1987-04-10 1988-11-01 Duphar Int Res
SE8705150D0 (sv) * 1987-12-23 1987-12-23 Haessle Ab Novel antiarrhythmic agents
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
GB8809314D0 (en) * 1988-04-20 1988-05-25 Wellcome Found Anti-hypertensive sulfonanilides
GB8819307D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Antiarrhythmic agents
US5086073A (en) * 1989-06-02 1992-02-04 John Wyeth & Brother Limited Composition for treating depression with aralkyl amines
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
US5084463A (en) * 1989-12-11 1992-01-28 American Home Products Corporation N-quinolinyl alkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing class III antiarrhythmic activity
WO1994003425A2 (en) * 1992-07-31 1994-02-17 Syntex (U.S.A.) Inc. Carbostyril derivatives for the treatment of arrhythmia
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
GB9404485D0 (en) * 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
DE4422517A1 (de) * 1994-06-28 1996-01-04 Dresden Arzneimittel Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ATE248802T1 (de) * 1994-08-04 2003-09-15 C & C Res Labs Neues amin-derivat, verfahren zur herstellung und dessen verwendung als anti-arrhythmisches mittel
EP0697407B1 (en) 1994-08-19 1997-06-25 MITSUI TOATSU CHEMICALS, Inc. Pyrimidinedione derivatives and antiarrhythmic compositions containing same
US5679706A (en) * 1994-09-30 1997-10-21 Bristol-Myers Squibb Company Combination of a potassium channel activator and an antiarrhythmic agent
FR2726267B1 (fr) * 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
CN1055679C (zh) * 1995-12-06 2000-08-23 中国药科大学 具有心血管活性的苯乙胺衍生物
CN1055682C (zh) * 1995-12-06 2000-08-23 中国药科大学 甲磺酰胺基苯乙胺衍生物的新制备方法
GB9722662D0 (en) * 1997-10-27 1997-12-24 Pfizer Ltd Polymorphs
HUP9702411A2 (hu) * 1997-12-11 2000-03-28 Gyógyszerkutató Intézet Kft. Fenoxi-alkil-amin-származékok és a vegyületeket tartalmazó antiaritmiás hatású gyógyszerkészítmények
AU2002250256B2 (en) * 2001-03-08 2008-04-03 Emory University pH-dependent NMDA receptor antagonists
CN100358865C (zh) * 2001-07-30 2008-01-02 中国科学院上海药物研究所 一类磺酰胺苯烷胺类化合物及其制备方法和用途
DE10201550A1 (de) * 2002-01-17 2003-07-31 Merck Patent Gmbh Phenoxy-Piperidine
WO2003091205A1 (fr) * 2002-04-26 2003-11-06 Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences Sulfamidophenylalkylamines, production et utilisation de ces dernieres
MXPA05013364A (es) * 2003-06-17 2006-03-17 Arena Pharm Inc Procedimiento para preparar 3-benzazepinas.
CN101792417A (zh) * 2003-06-17 2010-08-04 艾尼纳制药公司 用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
DE102004025726B4 (de) * 2004-05-26 2006-07-06 Roder, Hanno, Dr. Verwendung eines spezifischen K252a-Derivats zur Verhinderung oder Behandlung der Alzheimerschen Krankheit
JP2010513287A (ja) * 2006-12-14 2010-04-30 トータティス， インク． 癌治療のための組成物及び方法
CN103497114A (zh) * 2007-06-29 2014-01-08 埃莫里大学 用于神经保护的nmda受体拮抗剂
CN101372467B (zh) * 2007-08-23 2011-09-14 明德国际仓储贸易(上海)有限公司 具有n,n-二烷氨基的桥基化合物及所应用的染料化合物
WO2009111004A1 (en) 2008-03-04 2009-09-11 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
EP2443080A2 (en) 2009-06-18 2012-04-25 Arena Pharmaceuticals, Inc. Process for the preparation of 5-ht2c receptor agonists
WO2011153206A1 (en) 2010-06-02 2011-12-08 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-ht2c receptor agonists
SG188365A1 (en) 2010-09-01 2013-04-30 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
EP2611782A1 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
EP2611433A2 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
CN102531946A (zh) * 2012-01-05 2012-07-04 山东大学 3-甲氧基苯甲酰胺衍生物及其制备方法与应用
KR20190128001A (ko) 2012-10-09 2019-11-13 에자이 알앤드디 매니지먼트 가부시키가이샤 체중 관리 방법
FR3029113A1 (fr) 2014-12-02 2016-06-03 Univ Paris-Sud Composes pour le traitement des maladies mitochondriales
CZ307826B6 (cs) * 2017-12-01 2019-05-29 Farmak, A.S. Způsob přípravy N-[4-(2-{[2-(4-methansulfonamidofenoxy)ethyl](methyl)amino}ethyl)fenyl]methansulfonamidu (Dofetilidu)
US10888524B2 (en) 2018-02-05 2021-01-12 Enaltec Pharma Research Pvt. Ltd. Immediate release tablet of dofetilide

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR977261A (fr) * 1948-11-04 1951-03-29 équilibrage des masses dans les moteurs à combustion interne
US3478149A (en) * 1962-01-24 1969-11-11 Mead Johnson & Co Therapeutic compositions and methods employing sulfonamidophenethanolamines
GB993584A (bs) * 1962-01-24
US3852468A (en) * 1967-02-27 1974-12-03 Ici Ltd Alkanolamine derivatives as {62 -adrenergic blocking agents
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
US3758692A (en) * 1969-04-14 1973-09-11 Mead Johnson & Co Ylamines sympathomimetic process and compositions employing sulfonamidophenalk
GB1263987A (en) * 1969-05-30 1972-02-16 Allen & Hanburys Ltd Phenethylamine derivatives
BE757005A (fr) * 1969-10-02 1971-04-02 Bristol Myers Co Phenethanolamines substituees et procede pour leur preparation
GB1301134A (en) * 1970-07-18 1972-12-29 Pfizer Ltd SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
DK268579A (da) * 1978-07-03 1980-01-04 Lilly Co Eli Fremgangsmaade til fremstilling af phenetamolaminer
DE3061205D1 (en) * 1979-06-16 1983-01-05 Beecham Group Plc Secondary amines, their preparation and use in pharmaceutical compositions
DD157796A5 (de) * 1979-12-04 1982-12-08 Ciba Geigy Ag Verfahren zur herstellung neuer derivate des 2-amino-aethanols
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
EP0164865B1 (en) * 1984-05-04 1988-12-21 The Upjohn Company N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use
US4569801A (en) * 1984-10-15 1986-02-11 Eli Lilly And Company Alkylsulfonamidophenylalkylamines

Also Published As

Publication number Publication date
DK220287D0 (da) 1987-04-30
IL82373A (en) 1992-01-15
NO168527C (no) 1992-03-04
DK220287A (da) 1987-11-02
MY111142A (en) 1999-09-30
KR870011084A (ko) 1987-12-19
US4959366A (en) 1990-09-25
NZ220151A (en) 1989-02-24
EP0245997A2 (en) 1987-11-19
LV5715B4 (lv) 1996-02-20
CN1019801B (zh) 1992-12-30
US5079248A (en) 1992-01-07
DK175096B1 (da) 2004-06-01
FI88291B (fi) 1993-01-15
ATE74906T1 (de) 1992-05-15
AU578557B2 (en) 1988-10-27
LV5715A4 (lv) 1995-10-20
YU78387A (en) 1988-08-31
PT84782A (en) 1987-05-01
ES2033840T3 (es) 1993-04-01
NL300002I1 (nl) 2000-04-03
KR920014397A (ko) 1992-07-30
CN87103300A (zh) 1987-11-11
FI871898A0 (fi) 1987-04-29
NO168527B (no) 1991-11-25
EP0245997B1 (en) 1992-04-15
YU46541B (sh) 1993-11-16
CA1289140C (en) 1991-09-17
DE10075004I1 (de) 2000-04-13
PH23425A (en) 1989-08-07
FI871898A (fi) 1987-11-02
PL265418A1 (en) 1988-07-21
LU90519I2 (fr) 2000-04-10
HUT43558A (en) 1987-11-30
BA98301A (bs) 2001-09-14
EP0245997A3 (en) 1989-12-20
NL300002I2 (nl) 2000-05-01
YU73588A (en) 1990-04-30
KR930001339B1 (ko) 1993-02-26
HU196743B (en) 1989-01-30
PL149924B1 (en) 1990-04-30
FI88291C (fi) 1993-04-26
NO2001011I1 (no) 2001-07-16
IE871165L (en) 1987-11-01
AU7226087A (en) 1987-11-19
DE10075004I2 (de) 2006-02-02
NO871820D0 (no) 1987-04-30
PT84782B (pt) 1989-12-29
IE59366B1 (en) 1994-02-09
YU46195B (sh) 1993-05-28
NO871820L (no) 1987-11-02
DE3778201D1 (de) 1992-05-21
IL82373A0 (en) 1987-10-30
EG18188A (en) 1992-09-30
GR3004457T3 (bs) 1993-03-31

Similar Documents

Publication Publication Date Title
BA98211B1 (bs) Postupak za dobijanje antiaritmickih agenasa
BR8704582A (pt) Processo para preparar derivados de piridinacarboxamida
PT92419A (pt) Processo para a preparacao de tiazois substituidos uteis como fungicidas
ATE126517T1 (de) Verwendung von bis(3,4- dialkylbenzyliden)sorbitolacetale und diese enthaltende zusammensetzungen.
ES2036674T3 (es) Derivados de aminoindanos utiles como agentes antiarritmicos.
PT87050A (pt) Process for preparing indane sulfonamides antiarrhythmic agents
GB9012223D0 (en) Amines
PT94036A (pt) Processo para a preparacao de piridazinaminas anti-rinovirais