DK1412341T3 - Fremgangsmåde til fremstilling af racemisk citalopram og/eller S- eller R-citalopram ved separation af en blanding af R- og S-citalopram - Google Patents
Fremgangsmåde til fremstilling af racemisk citalopram og/eller S- eller R-citalopram ved separation af en blanding af R- og S-citalopramInfo
- Publication number
- DK1412341T3 DK1412341T3 DK02742848T DK02742848T DK1412341T3 DK 1412341 T3 DK1412341 T3 DK 1412341T3 DK 02742848 T DK02742848 T DK 02742848T DK 02742848 T DK02742848 T DK 02742848T DK 1412341 T3 DK1412341 T3 DK 1412341T3
- Authority
- DK
- Denmark
- Prior art keywords
- citalopram
- separating
- mixture
- preparation
- racemic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200100991 | 2001-06-25 | ||
| PCT/DK2002/000426 WO2003000672A1 (en) | 2001-06-25 | 2002-06-25 | Process for the preparation of racemic citalopram and/or s- or r-citalopram by separation of a mixture of r- and s-citalopram |
| EP02742848A EP1412341B1 (en) | 2001-06-25 | 2002-06-25 | Process for the preparation of racemic citalopram and/or s- or r-citalopram by separation of a mixture of r- and s-citalopram |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1412341T3 true DK1412341T3 (da) | 2005-04-04 |
Family
ID=8160584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK02742848T DK1412341T3 (da) | 2001-06-25 | 2002-06-25 | Fremgangsmåde til fremstilling af racemisk citalopram og/eller S- eller R-citalopram ved separation af en blanding af R- og S-citalopram |
Country Status (40)
| Country | Link |
|---|---|
| US (1) | US7112686B2 (me) |
| EP (1) | EP1412341B1 (me) |
| JP (2) | JP4377219B2 (me) |
| KR (4) | KR100902530B1 (me) |
| CN (2) | CN101440079B (me) |
| AR (2) | AR034612A1 (me) |
| AT (1) | ATE284395T1 (me) |
| BG (1) | BG66372B1 (me) |
| BR (1) | BRPI0210574B8 (me) |
| CA (2) | CA2450890C (me) |
| CO (1) | CO5550420A2 (me) |
| CZ (1) | CZ305034B6 (me) |
| DE (1) | DE60202216T2 (me) |
| DK (1) | DK1412341T3 (me) |
| EA (1) | EA006446B1 (me) |
| ES (1) | ES2233834T3 (me) |
| HK (2) | HK1068627A1 (me) |
| HR (1) | HRP20031075B1 (me) |
| HU (1) | HU228476B1 (me) |
| IL (1) | IL159229A0 (me) |
| IS (1) | IS2426B (me) |
| JO (1) | JO2389B1 (me) |
| MA (1) | MA26260A1 (me) |
| ME (2) | ME00027B (me) |
| MX (1) | MXPA03011770A (me) |
| MY (1) | MY133471A (me) |
| NO (2) | NO329873B1 (me) |
| NZ (1) | NZ530104A (me) |
| PE (1) | PE20030122A1 (me) |
| PL (1) | PL366560A1 (me) |
| PT (1) | PT1412341E (me) |
| RS (1) | RS50673B (me) |
| SI (1) | SI1412341T1 (me) |
| SK (1) | SK287696B6 (me) |
| TN (1) | TNSN02062A1 (me) |
| TW (1) | TWI236473B (me) |
| UA (1) | UA75147C2 (me) |
| UY (2) | UY27356A1 (me) |
| WO (1) | WO2003000672A1 (me) |
| ZA (1) | ZA200309633B (me) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20040991A1 (es) | 2002-08-12 | 2004-12-27 | Lundbeck & Co As H | Separacion de intermediarios para la preparacion de escitalopram |
| MEP5708A (xx) * | 2002-12-23 | 2010-02-10 | Lundbeck & Co As H | Postupak pripremanja racemskog citalopram diola i/ili r-citalopram diola i upotreba takvih diola za pripremanje racemskog citaloprama , r-citaloprama i/ili s-citaloprama. |
| EP2363389A1 (en) * | 2002-12-23 | 2011-09-07 | H. Lundbeck A/S | A process for the preparation of racemic citalopram diol and/or S- or R-citalopram diols and the use of such diols for the preparation of racemic citalopram, R-citalopram and/or S-citalopram |
| ATE388947T1 (de) | 2002-12-23 | 2008-03-15 | Lundbeck & Co As H | Escitalopramhydrobromid und ein verfahren zu dessen herstellung |
| TR200504022T1 (tr) * | 2003-03-24 | 2006-08-21 | Hetero Drugs Limited | (S)-sitalopram oksalatın yeni sıvı kristal formları. |
| CN100569765C (zh) | 2003-12-19 | 2009-12-16 | 杭州民生药业集团有限公司 | 西酞普兰中间体晶体碱 |
| TWI339651B (en) | 2004-02-12 | 2011-04-01 | Lundbeck & Co As H | Method for the separation of intermediates which may be used for the preparation of escitalopram |
| EP1732514A1 (en) * | 2004-03-05 | 2006-12-20 | H. Lundbeck A/S | Crystalline composition containing escitalopram oxalate |
| US20050196453A1 (en) | 2004-03-05 | 2005-09-08 | H. Lundbeck A/S | Crystalline composition containing escitalopram |
| ITMI20040717A1 (it) | 2004-04-09 | 2004-07-09 | Adorkem Technology Spa | Procedimento chemo-enzimatico per la preparazione dell'escitalopram |
| JP2006008603A (ja) * | 2004-06-25 | 2006-01-12 | Sumitomo Chemical Co Ltd | 光学活性シタロプラムの製造方法、その中間体およびその製造方法 |
| US7989645B2 (en) * | 2004-08-23 | 2011-08-02 | Sun Pharma Global Fze | Process for preparation of citalopram and enantiomers |
| EP1797060A2 (en) | 2004-08-23 | 2007-06-20 | Sun Pharmaceutical Industries Limited | "process for preparation of citalopram and enantiomers" |
| WO2006123243A2 (en) * | 2005-05-20 | 2006-11-23 | Aurobindo Pharma Limited | Pharmaceutical dosage forms comprising escitalopram in form of granules |
| TWI347942B (en) * | 2005-06-22 | 2011-09-01 | Lundbeck & Co As H | Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base |
| US7834201B2 (en) | 2005-06-22 | 2010-11-16 | H. Lundbeck A/S | Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base |
| JP2009511606A (ja) | 2005-10-14 | 2009-03-19 | ハー・ルンドベック・アクチエゼルスカベット | エスシタロプラムおよびブプロピオンの低用量の併用を用いる中枢神経系障害の治療方法 |
| WO2008059514A2 (en) * | 2006-07-31 | 2008-05-22 | Cadila Healthcare Limited | Process for preparing escitalopram |
| US8022232B2 (en) * | 2007-09-11 | 2011-09-20 | H. Lundbeck A/S | Method for manufacture of escitalopram |
| FI121570B (fi) | 2007-09-11 | 2011-01-14 | Lundbeck & Co As H | Menetelmä essitalopraamin valmistamiseksi |
| CN100548974C (zh) * | 2007-10-11 | 2009-10-14 | 浙江大学 | 西酞普兰中间体的萃取分离方法 |
| CN101560199B (zh) * | 2008-04-16 | 2013-09-18 | 北京德众万全药物技术开发有限公司 | 一种依地普仑的制备方法 |
| TWI381813B (zh) | 2010-01-12 | 2013-01-11 | Taiwan Paiho Ltd | A Velcro assembly for a foamed article and a foamed article comprising the adhesive tape assembly |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8419963D0 (en) * | 1984-08-06 | 1984-09-12 | Lundbeck & Co As H | Intermediate compound and method |
| GB8814057D0 (en) * | 1988-06-14 | 1988-07-20 | Lundbeck & Co As H | New enantiomers & their isolation |
| TR200401456T1 (tr) * | 1999-10-25 | 2005-04-21 | H. Lundbeck A/S | Sitalopram hazırlanması için yöntem. |
-
2002
- 2002-06-21 AR ARP020102350A patent/AR034612A1/es active IP Right Grant
- 2002-06-23 JO JO200265A patent/JO2389B1/en active
- 2002-06-24 PE PE2002000551A patent/PE20030122A1/es active IP Right Grant
- 2002-06-24 TN TNTNSN02062A patent/TNSN02062A1/en unknown
- 2002-06-25 UA UA20031211986A patent/UA75147C2/uk unknown
- 2002-06-25 CN CN2008102158851A patent/CN101440079B/zh not_active Expired - Lifetime
- 2002-06-25 CA CA2450890A patent/CA2450890C/en not_active Expired - Fee Related
- 2002-06-25 TW TW091113845A patent/TWI236473B/zh not_active IP Right Cessation
- 2002-06-25 US US10/482,000 patent/US7112686B2/en not_active Expired - Lifetime
- 2002-06-25 IL IL15922902A patent/IL159229A0/xx active IP Right Grant
- 2002-06-25 KR KR1020037016853A patent/KR100902530B1/ko active IP Right Grant
- 2002-06-25 CA CA2691149A patent/CA2691149C/en not_active Expired - Fee Related
- 2002-06-25 ME MEP-2008-15A patent/ME00027B/me unknown
- 2002-06-25 ME MEP-15/08A patent/MEP1508A/xx unknown
- 2002-06-25 SI SI200230078T patent/SI1412341T1/xx unknown
- 2002-06-25 UY UY27356A patent/UY27356A1/es not_active IP Right Cessation
- 2002-06-25 MX MXPA03011770A patent/MXPA03011770A/es active IP Right Grant
- 2002-06-25 PL PL02366560A patent/PL366560A1/xx not_active Application Discontinuation
- 2002-06-25 PT PT02742848T patent/PT1412341E/pt unknown
- 2002-06-25 KR KR1020107006751A patent/KR20100052550A/ko not_active Application Discontinuation
- 2002-06-25 SK SK51-2004A patent/SK287696B6/sk unknown
- 2002-06-25 JP JP2003507077A patent/JP4377219B2/ja not_active Expired - Lifetime
- 2002-06-25 CZ CZ2004-131A patent/CZ305034B6/cs not_active IP Right Cessation
- 2002-06-25 CN CNB028126688A patent/CN100429208C/zh not_active Expired - Lifetime
- 2002-06-25 KR KR1020097004586A patent/KR100939945B1/ko active IP Right Grant
- 2002-06-25 DK DK02742848T patent/DK1412341T3/da active
- 2002-06-25 DE DE60202216T patent/DE60202216T2/de not_active Expired - Lifetime
- 2002-06-25 RS YUP-1014/03A patent/RS50673B/sr unknown
- 2002-06-25 MA MA26713A patent/MA26260A1/fr unknown
- 2002-06-25 WO PCT/DK2002/000426 patent/WO2003000672A1/en active Application Filing
- 2002-06-25 HU HU0400293A patent/HU228476B1/hu unknown
- 2002-06-25 AT AT02742848T patent/ATE284395T1/de active
- 2002-06-25 KR KR1020087026708A patent/KR20080100498A/ko active Application Filing
- 2002-06-25 EA EA200400082A patent/EA006446B1/ru not_active IP Right Cessation
- 2002-06-25 NZ NZ530104A patent/NZ530104A/en not_active IP Right Cessation
- 2002-06-25 EP EP02742848A patent/EP1412341B1/en not_active Expired - Lifetime
- 2002-06-25 MY MYPI20022382A patent/MY133471A/en unknown
- 2002-06-25 ES ES02742848T patent/ES2233834T3/es not_active Expired - Lifetime
- 2002-06-25 BR BRPI0210574A patent/BRPI0210574B8/pt not_active IP Right Cessation
-
2003
- 2003-12-08 IS IS7068A patent/IS2426B/is unknown
- 2003-12-11 ZA ZA2003/09633A patent/ZA200309633B/en unknown
- 2003-12-18 NO NO20035671A patent/NO329873B1/no not_active IP Right Cessation
- 2003-12-23 HR HR20031075A patent/HRP20031075B1/xx not_active IP Right Cessation
-
2004
- 2004-01-14 BG BG108532A patent/BG66372B1/bg unknown
- 2004-01-22 CO CO04004620A patent/CO5550420A2/es not_active Application Discontinuation
-
2005
- 2005-02-07 HK HK05101034.1A patent/HK1068627A1/xx not_active IP Right Cessation
-
2009
- 2009-04-17 JP JP2009101188A patent/JP5064436B2/ja not_active Expired - Lifetime
- 2009-11-12 HK HK09110569.1A patent/HK1132729A1/xx not_active IP Right Cessation
-
2010
- 2010-10-13 NO NO20101420A patent/NO335106B1/no not_active IP Right Cessation
-
2011
- 2011-10-19 AR ARP110103869A patent/AR083483A2/es active IP Right Grant
-
2014
- 2014-11-21 UY UY0001035850A patent/UY35850A/es not_active IP Right Cessation
Also Published As
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