IS5884A - Aðferð til framleiðslu á hreinu sítalóprami - Google Patents

Aðferð til framleiðslu á hreinu sítalóprami

Info

Publication number
IS5884A
IS5884A IS5884A IS5884A IS5884A IS 5884 A IS5884 A IS 5884A IS 5884 A IS5884 A IS 5884A IS 5884 A IS5884 A IS 5884A IS 5884 A IS5884 A IS 5884A
Authority
IS
Iceland
Prior art keywords
production
pure citalopram
citalopram
pure
Prior art date
Application number
IS5884A
Other languages
English (en)
Inventor
Castellin Andrea
Sbrogiþ Federico
Volpe Giulio
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of IS5884A publication Critical patent/IS5884A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS5884A 2000-12-28 2001-03-09 Aðferð til framleiðslu á hreinu sítalóprami IS5884A (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200001943 2000-12-28

Publications (1)

Publication Number Publication Date
IS5884A true IS5884A (is) 2002-06-28

Family

ID=8159933

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5884A IS5884A (is) 2000-12-28 2001-03-09 Aðferð til framleiðslu á hreinu sítalóprami

Country Status (41)

Country Link
US (2) US6855834B2 (is)
EP (1) EP1181272B1 (is)
JP (1) JP2003519121A (is)
KR (1) KR100430746B1 (is)
CN (1) CN1366526A (is)
AR (1) AR029898A1 (is)
AT (2) ATE222899T1 (is)
AU (3) AU3920201A (is)
BE (2) BE1013417A6 (is)
BG (1) BG106219A (is)
BR (1) BR0106271A (is)
CA (1) CA2359810C (is)
CH (1) CH691536A5 (is)
CZ (1) CZ293140B6 (is)
DE (1) DE60100016T2 (is)
DK (1) DK1181272T3 (is)
EA (1) EA003459B1 (is)
ES (2) ES2181663T3 (is)
FI (2) FI108640B (is)
FR (1) FR2818977B1 (is)
GB (2) GB2356199B (is)
GR (1) GR20010100131A (is)
HK (1) HK1049332A1 (is)
HR (1) HRP20020005A2 (is)
HU (2) HU0101028D0 (is)
IE (2) IES20010253A2 (is)
IL (1) IL147162A0 (is)
IS (1) IS5884A (is)
IT (1) ITMI20010604A1 (is)
MX (1) MXPA01013336A (is)
NL (1) NL1017534C1 (is)
NO (1) NO313047B1 (is)
NZ (1) NZ516299A (is)
PL (1) PL353369A1 (is)
PT (1) PT1181272E (is)
SE (1) SE0103044L (is)
SK (1) SK284418B6 (is)
TR (1) TR200200018T1 (is)
UA (1) UA71635C2 (is)
WO (1) WO2001047877A2 (is)
ZA (1) ZA200110133B (is)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
IL145615A0 (en) * 1999-04-14 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
HK1043129B (zh) 1999-10-25 2004-10-21 H‧隆德贝克有限公司 西酞普蘭的製備方法
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
NZ519739A (en) 1999-12-28 2004-03-26 H Method for the preparation of citalopram
PT1246813E (pt) 1999-12-30 2004-02-27 Lundbeck & Co As H Metodo para a preparacao de citalopram
WO2001051477A1 (en) 2000-01-14 2001-07-19 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
SK14602002A3 (sk) 2000-03-13 2003-02-04 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
BR0109364A (pt) 2000-03-13 2002-12-24 Lundbeck & Co As H Métodos para fabricação de citalopram através de alquilação escalonada de 5-substituìda 1- (4-fluorofenil) - 1,3- diidroisobenzofuranos e citalopram
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
TR200202168T2 (tr) * 2000-03-16 2002-12-23 H. Lundbeck A/S 5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
TR200201166T1 (tr) 2000-12-22 2002-10-21 H.Lundbecks A/S Saf sitalopram hazırlanması için yöntem
JP2003519121A (ja) 2000-12-28 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット 純粋なシタロプラムの製造方法
GB2376945A (en) * 2001-06-27 2002-12-31 Cipla Ltd Citalopram preparation
WO2003057132A2 (en) 2002-01-07 2003-07-17 Sun Pharmaceutical Industries Limited Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
ES2194597B2 (es) * 2002-01-25 2004-08-01 Esteve Quimica, S.A. Procedimiento para la obtencion de citalopram.
GB0204607D0 (en) 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
EP1486492A3 (en) * 2003-06-10 2005-02-23 Sun Pharmaceuticals Industries Ltd. A process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran.
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
CN120097946B (zh) * 2025-02-28 2026-06-19 浙江工业大学 一种应用脱水膜强化5-氰二醇盐酸盐醚化制西酞普兰溴酸盐的方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL135959C (is) 1964-12-23
GB1143703A (is) 1965-03-18
DE1619713A1 (de) * 1967-03-29 1970-12-17 Leybold Heraeus Gmbh & Co Kg Vorrichtung zur Vakuum- und Kurzwegdestillation
DE2135085C3 (de) 1971-07-14 1981-12-03 Basf Ag, 6700 Ludwigshafen Verfahren zur Wiedergewinnung von Caprolactam aus einem Gemisch, das Caprolactam und dessen Oligomere enthält
DE2442426C2 (de) 1974-09-05 1983-04-07 Bayer Ag, 5090 Leverkusen Diisocyanatodiketene, Verfahren zu deren Herstellung und deren Verwendung
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
IT8020902A0 (it) 1980-03-25 1980-03-25 Snia Viscosa Procedimento ed apparecchiatura per la separazione continua per via termica di miscele liquide dicomposti termolabili.
JPS6082101A (ja) 1983-10-13 1985-05-10 Mitsui Toatsu Chem Inc 高沸点重合性化合物の薄膜蒸留による精製方法
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
FR2656305B1 (fr) 1989-12-22 1992-04-10 Norsolor Sa Procede de purification du (meth)acrylate de glycidyle.
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
US5582692A (en) 1994-10-07 1996-12-10 Artisan Industries, Inc. Method for the purification of vitamin E
US6136991A (en) * 1996-05-21 2000-10-24 Exxon Chemical Patents Inc. Glycidyl ester adducts having increased glass transition temperatures
WO1997044335A1 (en) 1996-05-21 1997-11-27 Exxon Chemical Patents Inc. Purification of glycidyl esters by thin film evaporation
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
JP3526581B2 (ja) 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
DE19734673A1 (de) 1997-08-11 1999-02-18 Rwe Dea Ag Verfahren zur Herstellung von metallfreien Guerbetalkoholen
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CN1286687A (zh) 1997-11-11 2001-03-07 H·隆德贝克有限公司 制备西酞普兰的方法
EP0965593B2 (en) 1998-06-19 2008-12-03 Shin-Etsu Chemical Co., Ltd. Distillation of (meth)acryloxybearing alkoxysilane
WO2000023431A1 (en) * 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
HK1043130B (zh) 1998-12-23 2005-03-04 H‧隆德贝克有限公司 制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
IL145615A0 (en) 1999-04-14 2002-06-30 Lundbeck & Co As H Method for the preparation of citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
TR200201166T1 (tr) 2000-12-22 2002-10-21 H.Lundbecks A/S Saf sitalopram hazırlanması için yöntem
JP2003519121A (ja) 2000-12-28 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット 純粋なシタロプラムの製造方法
US6781003B1 (en) * 2003-06-09 2004-08-24 Aurobindo Pharma Ltd. Preparation of pure citalopram

Also Published As

Publication number Publication date
FR2818977A1 (fr) 2002-07-05
SE0103044L (sv) 2002-06-29
KR100430746B1 (ko) 2004-05-10
FI109023B (fi) 2002-05-15
JP2003519121A (ja) 2003-06-17
IES20010632A2 (en) 2002-03-06
KR20020073379A (ko) 2002-09-26
PL353369A1 (pl) 2003-11-17
GB0117095D0 (en) 2001-09-05
MXPA01013336A (es) 2002-07-09
AU2001100399B4 (en) 2002-03-21
HUP0102818A2 (hu) 2001-12-28
GB2361697A (en) 2001-10-31
NO20011272D0 (no) 2001-03-13
UA71635C2 (uk) 2004-12-15
AU3920201A (en) 2001-07-09
ES2181663T3 (es) 2003-03-01
NO20011272L (no) 2002-07-01
GB0105981D0 (en) 2001-05-02
FI20011578A0 (fi) 2001-07-26
SE0103044D0 (sv) 2001-09-14
EP1181272B1 (en) 2002-08-28
BR0106271A (pt) 2002-05-21
HUP0102818A3 (en) 2003-07-28
CN1366526A (zh) 2002-08-28
DE60100016T2 (de) 2003-04-17
HRP20020005A2 (en) 2003-04-30
DK1181272T3 (da) 2002-12-30
AU750006B1 (en) 2002-07-11
US20030178295A1 (en) 2003-09-25
ZA200110133B (en) 2003-01-13
IES20010253A2 (en) 2002-03-06
FI20010501A0 (fi) 2001-03-13
GB2356199A (en) 2001-05-16
TR200200018T1 (tr) 2002-06-21
ATE222899T1 (de) 2002-09-15
BG106219A (bg) 2002-08-30
EA200200016A1 (ru) 2002-04-25
BE1013417A6 (fr) 2001-12-04
CA2359810A1 (en) 2001-07-05
WO2001047877A3 (en) 2001-12-27
HU0101028D0 (en) 2001-05-28
PT1181272E (pt) 2003-01-31
BE1013316A6 (fr) 2001-11-06
CZ2001891A3 (cs) 2002-08-14
FI108640B (fi) 2002-02-28
CH691536A5 (de) 2001-08-15
SK18472001A3 (sk) 2002-05-09
DE60100016D1 (de) 2002-10-02
NL1017534C1 (nl) 2001-04-26
US20020087012A1 (en) 2002-07-04
CA2359810C (en) 2002-11-05
EP1181272A2 (en) 2002-02-27
HK1049332A1 (zh) 2003-05-09
ES2170733B1 (es) 2003-12-16
US6855834B2 (en) 2005-02-15
IL147162A0 (en) 2002-08-14
FR2818977B1 (fr) 2003-12-05
ITMI20010604A0 (it) 2001-03-22
NZ516299A (en) 2002-12-20
ITMI20010604A1 (it) 2002-09-22
SK284418B6 (sk) 2005-04-01
ES2170733A1 (es) 2002-08-01
HU0102818D0 (en) 2001-09-28
CZ293140B6 (cs) 2004-02-18
WO2001047877A2 (en) 2001-07-05
AU2001100399A4 (en) 2001-11-01
AT4368U1 (de) 2001-06-25
GR20010100131A (el) 2002-10-09
EA003459B1 (ru) 2003-06-26
GB2356199B (en) 2001-10-03
AR029898A1 (es) 2003-07-23
NO313047B1 (no) 2002-08-05

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