IL147162A0 - Process for the preparation of pure citalopram - Google Patents

Process for the preparation of pure citalopram

Info

Publication number
IL147162A0
IL147162A0 IL14716201A IL14716201A IL147162A0 IL 147162 A0 IL147162 A0 IL 147162A0 IL 14716201 A IL14716201 A IL 14716201A IL 14716201 A IL14716201 A IL 14716201A IL 147162 A0 IL147162 A0 IL 147162A0
Authority
IL
Israel
Prior art keywords
preparation
pure citalopram
citalopram
pure
Prior art date
Application number
IL14716201A
Other languages
English (en)
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of IL147162A0 publication Critical patent/IL147162A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL14716201A 2000-12-28 2001-03-07 Process for the preparation of pure citalopram IL147162A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001943 2000-12-28
PCT/DK2001/000148 WO2001047877A2 (en) 2000-12-28 2001-03-07 Process for the preparation of pure citalopram

Publications (1)

Publication Number Publication Date
IL147162A0 true IL147162A0 (en) 2002-08-14

Family

ID=8159933

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14716201A IL147162A0 (en) 2000-12-28 2001-03-07 Process for the preparation of pure citalopram

Country Status (41)

Country Link
US (2) US6855834B2 (xx)
EP (1) EP1181272B1 (xx)
JP (1) JP2003519121A (xx)
KR (1) KR100430746B1 (xx)
CN (1) CN1366526A (xx)
AR (1) AR029898A1 (xx)
AT (2) ATE222899T1 (xx)
AU (3) AU2001100399B4 (xx)
BE (2) BE1013417A6 (xx)
BG (1) BG106219A (xx)
BR (1) BR0106271A (xx)
CA (1) CA2359810C (xx)
CH (1) CH691536A5 (xx)
CZ (1) CZ293140B6 (xx)
DE (1) DE60100016T2 (xx)
DK (1) DK1181272T3 (xx)
EA (1) EA003459B1 (xx)
ES (2) ES2181663T3 (xx)
FI (2) FI108640B (xx)
FR (1) FR2818977B1 (xx)
GB (2) GB2356199B (xx)
GR (1) GR20010100131A (xx)
HK (1) HK1049332A1 (xx)
HR (1) HRP20020005A2 (xx)
HU (2) HU0101028D0 (xx)
IE (2) IES20010253A2 (xx)
IL (1) IL147162A0 (xx)
IS (1) IS5884A (xx)
IT (1) ITMI20010604A1 (xx)
MX (1) MXPA01013336A (xx)
NL (1) NL1017534C1 (xx)
NO (1) NO313047B1 (xx)
NZ (1) NZ516299A (xx)
PL (1) PL353369A1 (xx)
PT (1) PT1181272E (xx)
SE (1) SE0103044L (xx)
SK (1) SK284418B6 (xx)
TR (1) TR200200018T1 (xx)
UA (1) UA71635C2 (xx)
WO (1) WO2001047877A2 (xx)
ZA (1) ZA200110133B (xx)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
ATE237604T1 (de) * 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
HUP0200169A3 (en) 1999-10-25 2002-11-28 Lundbeck & Co As H Method for the preparation of citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
WO2001047909A1 (en) 1999-12-28 2001-07-05 H. Lundbeck A/S Method for the preparation of citalopram
PL198803B1 (pl) 1999-12-30 2008-07-31 Lundbeck & Co As H Sposób wytwarzania 5-cyjano-3H-izobenzofuran-1-onu
ES2206177T3 (es) 2000-01-14 2004-05-16 H. Lundbeck A/S Metodo para la preparacion de 5-cianoftalida.
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
BR0109176A (pt) 2000-03-13 2003-04-22 Lundbeck & Co As H Método para preparação de citalopram e composto da fórmula
CA2402553A1 (en) 2000-03-13 2001-09-20 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
EP1274699A1 (en) * 2000-03-16 2003-01-15 H. Lundbeck A/S Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354880C (en) 2000-08-18 2003-06-03 H. Lundbeck A/S Method for the preparation of citalopram
IL147226A (en) 2000-12-22 2006-04-10 Lundbeck & Co As H Process for the preparation of pure cithalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro
GB2376945A (en) * 2001-06-27 2002-12-31 Cipla Ltd Citalopram preparation
AU2003222435A1 (en) 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
ES2194597B2 (es) * 2002-01-25 2004-08-01 Esteve Quimica, S.A. Procedimiento para la obtencion de citalopram.
GB0204607D0 (en) 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL135959C (xx) 1964-12-23
GB1143702A (xx) 1965-03-18
DE1619713A1 (de) * 1967-03-29 1970-12-17 Leybold Heraeus Gmbh & Co Kg Vorrichtung zur Vakuum- und Kurzwegdestillation
DE2135085C3 (de) 1971-07-14 1981-12-03 Basf Ag, 6700 Ludwigshafen Verfahren zur Wiedergewinnung von Caprolactam aus einem Gemisch, das Caprolactam und dessen Oligomere enthält
DE2442426C2 (de) 1974-09-05 1983-04-07 Bayer Ag, 5090 Leverkusen Diisocyanatodiketene, Verfahren zu deren Herstellung und deren Verwendung
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
IT8020902A0 (it) 1980-03-25 1980-03-25 Snia Viscosa Procedimento ed apparecchiatura per la separazione continua per via termica di miscele liquide dicomposti termolabili.
JPS6082101A (ja) 1983-10-13 1985-05-10 Mitsui Toatsu Chem Inc 高沸点重合性化合物の薄膜蒸留による精製方法
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
FR2656305B1 (fr) 1989-12-22 1992-04-10 Norsolor Sa Procede de purification du (meth)acrylate de glycidyle.
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
US5582692A (en) 1994-10-07 1996-12-10 Artisan Industries, Inc. Method for the purification of vitamin E
DE69725717T2 (de) 1996-05-21 2004-07-29 Exxonmobil Chemical Patents Inc., Baytown Reinigung von glycidylestern durch dünnschichtverdampfung
US6136991A (en) * 1996-05-21 2000-10-24 Exxon Chemical Patents Inc. Glycidyl ester adducts having increased glass transition temperatures
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
JP3526581B2 (ja) 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
DE19734673A1 (de) 1997-08-11 1999-02-18 Rwe Dea Ag Verfahren zur Herstellung von metallfreien Guerbetalkoholen
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CZ292911B6 (cs) 1997-11-11 2004-01-14 H. Lundbeck A/S Způsob výroby citalopramu
DE69920329T3 (de) 1998-06-19 2009-07-09 Shin-Etsu Chemical Co., Ltd. Destillationsverfahren für (Meth)acryloxysilane
PL199423B1 (pl) * 1998-10-20 2008-09-30 Lundbeck & Co As H Sposób wytwarzania citalopramu
TR200101796T2 (tr) 1998-12-23 2001-11-21 H. Lundbeck A/S 5-Siyanofitalitin preparasyonuna yönelik metot
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
ATE237604T1 (de) 1999-04-14 2003-05-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
GB2360281B (en) 1999-10-25 2002-01-16 Lundbeck & Co As H Method for the preparation of citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL147226A (en) 2000-12-22 2006-04-10 Lundbeck & Co As H Process for the preparation of pure cithalopram
PT1181272E (pt) 2000-12-28 2003-01-31 Lundbeck & Co As H Processo para a preparacao de citalopram puro
US6781003B1 (en) * 2003-06-09 2004-08-24 Aurobindo Pharma Ltd. Preparation of pure citalopram

Also Published As

Publication number Publication date
FR2818977B1 (fr) 2003-12-05
HUP0102818A3 (en) 2003-07-28
ES2181663T3 (es) 2003-03-01
BE1013316A6 (fr) 2001-11-06
SE0103044L (sv) 2002-06-29
NZ516299A (en) 2002-12-20
WO2001047877A2 (en) 2001-07-05
BG106219A (en) 2002-08-30
NO20011272L (no) 2002-07-01
CH691536A5 (de) 2001-08-15
PT1181272E (pt) 2003-01-31
AU2001100399B4 (en) 2002-03-21
EP1181272B1 (en) 2002-08-28
HUP0102818A2 (hu) 2001-12-28
EP1181272A2 (en) 2002-02-27
IES20010632A2 (en) 2002-03-06
DE60100016D1 (de) 2002-10-02
JP2003519121A (ja) 2003-06-17
ATE222899T1 (de) 2002-09-15
HRP20020005A2 (en) 2003-04-30
ES2170733A1 (es) 2002-08-01
CN1366526A (zh) 2002-08-28
EA003459B1 (ru) 2003-06-26
AT4368U1 (de) 2001-06-25
GB0105981D0 (en) 2001-05-02
HU0102818D0 (en) 2001-09-28
CZ2001891A3 (cs) 2002-08-14
SK18472001A3 (sk) 2002-05-09
AU3920201A (en) 2001-07-09
NO313047B1 (no) 2002-08-05
BR0106271A (pt) 2002-05-21
KR100430746B1 (ko) 2004-05-10
FI20010501A0 (fi) 2001-03-13
GB2356199A (en) 2001-05-16
PL353369A1 (en) 2003-11-17
AR029898A1 (es) 2003-07-23
HK1049332A1 (zh) 2003-05-09
GB0117095D0 (en) 2001-09-05
KR20020073379A (ko) 2002-09-26
WO2001047877A3 (en) 2001-12-27
HU0101028D0 (en) 2001-05-28
IS5884A (is) 2002-06-28
IES20010253A2 (en) 2002-03-06
US20020087012A1 (en) 2002-07-04
NL1017534C1 (nl) 2001-04-26
ITMI20010604A1 (it) 2002-09-22
SE0103044D0 (sv) 2001-09-14
GB2361697A (en) 2001-10-31
CA2359810C (en) 2002-11-05
BE1013417A6 (fr) 2001-12-04
NO20011272D0 (no) 2001-03-13
UA71635C2 (uk) 2004-12-15
ZA200110133B (en) 2003-01-13
FR2818977A1 (fr) 2002-07-05
AU750006B1 (en) 2002-07-11
ITMI20010604A0 (it) 2001-03-22
ES2170733B1 (es) 2003-12-16
EA200200016A1 (ru) 2002-04-25
AU2001100399A4 (en) 2001-11-01
US6855834B2 (en) 2005-02-15
TR200200018T1 (tr) 2002-06-21
FI20011578A0 (fi) 2001-07-26
MXPA01013336A (es) 2002-07-09
DE60100016T2 (de) 2003-04-17
GB2356199B (en) 2001-10-03
CA2359810A1 (en) 2001-07-05
CZ293140B6 (cs) 2004-02-18
SK284418B6 (sk) 2005-04-01
DK1181272T3 (da) 2002-12-30
GR20010100131A (el) 2002-10-09
FI108640B (fi) 2002-02-28
US20030178295A1 (en) 2003-09-25

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