NO20011271A - Fremgangsmåte for fremstilling av ren citalopram - Google Patents

Fremgangsmåte for fremstilling av ren citalopram

Info

Publication number
NO20011271A
NO20011271A NO20011271A NO20011271A NO20011271A NO 20011271 A NO20011271 A NO 20011271A NO 20011271 A NO20011271 A NO 20011271A NO 20011271 A NO20011271 A NO 20011271A NO 20011271 A NO20011271 A NO 20011271A
Authority
NO
Norway
Prior art keywords
preparation
pure citalopram
citalopram
pure
Prior art date
Application number
NO20011271A
Other languages
English (en)
Other versions
NO20011271D0 (no
NO312462B1 (no
Inventor
Robert Dancer
Marco Villa
Federico Sbrogiò
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of NO20011271D0 publication Critical patent/NO20011271D0/no
Publication of NO312462B1 publication Critical patent/NO312462B1/no
Publication of NO20011271A publication Critical patent/NO20011271A/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO20011271A 2000-12-22 2001-03-13 Fremgangsmåte for fremstilling av ren citalopram NO20011271A (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200001929 2000-12-22

Publications (3)

Publication Number Publication Date
NO20011271D0 NO20011271D0 (no) 2001-03-13
NO312462B1 NO312462B1 (no) 2002-05-13
NO20011271A true NO20011271A (no) 2002-05-13

Family

ID=8159922

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20011271A NO20011271A (no) 2000-12-22 2001-03-13 Fremgangsmåte for fremstilling av ren citalopram

Country Status (43)

Country Link
US (1) US6455710B1 (no)
EP (2) EP1462447A3 (no)
JP (1) JP3798982B2 (no)
KR (1) KR100439329B1 (no)
CN (1) CN1282648C (no)
AR (1) AR030056A1 (no)
AT (2) ATE277920T1 (no)
AU (2) AU2001100405B4 (no)
BE (2) BE1013212A6 (no)
BG (1) BG65131B1 (no)
BR (1) BR0106272A (no)
CA (1) CA2360303C (no)
CH (1) CH691535A5 (no)
CZ (1) CZ292200B6 (no)
DE (2) DE60105926T2 (no)
DK (1) DK1181713T3 (no)
EA (1) EA003581B1 (no)
ES (2) ES2228824T3 (no)
FI (2) FI108639B (no)
FR (1) FR2812877B1 (no)
GB (1) GB2357763B (no)
GR (1) GR1003874B (no)
HK (1) HK1048812B (no)
HR (1) HRP20020004A2 (no)
HU (2) HU0101029D0 (no)
IE (1) IES20010254A2 (no)
IL (1) IL147226A (no)
IS (1) IS2060B (no)
IT (1) ITMI20010602A1 (no)
MX (1) MXPA01013151A (no)
NL (2) NL1017525C1 (no)
NO (1) NO20011271A (no)
NZ (1) NZ516298A (no)
PL (1) PL205724B1 (no)
PT (1) PT1181713E (no)
SE (1) SE517623C2 (no)
SG (1) SG167655A1 (no)
SI (1) SI1181713T1 (no)
SK (2) SK284428B6 (no)
TR (1) TR200201166T1 (no)
UA (1) UA71634C2 (no)
WO (1) WO2001045483A2 (no)
ZA (1) ZA200110179B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
SK287139B6 (sk) 1999-10-25 2010-01-07 H. Lundbeck A/S Spôsob prípravy citalopramu
AU778751B2 (en) 1999-12-28 2004-12-16 H. Lundbeck A/S Method for the preparation of citalopram
EP1246813B1 (en) 1999-12-30 2003-11-05 H. Lundbeck A/S Method for the preparation of citalopram
EA005134B1 (ru) 2000-01-14 2004-12-30 Х.Лундбекк А/С Способ получения 5-цианофталида
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EA200200969A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Способ получения циталопрама
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
TR200202195T2 (tr) 2000-03-13 2002-12-23 H. Lundbeck A/S 5-Yer değiştirmiş 1-(4-florofenil)-1,3- dihidroizobenzofuran'ın adım adım alkillenmesi
ES2214400T3 (es) 2000-03-14 2004-09-16 H. Lundbeck A/S Metodo para la preparacion de citalopram.
JP2003527388A (ja) * 2000-03-16 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット ５−シアノ−１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフランの製造方法
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
CA2359810C (en) 2000-12-28 2002-11-05 H. Lundbeck A/S Process for the preparation of pure citalopram
GB0105627D0 (en) * 2001-03-07 2001-04-25 Cipla Ltd Preparation of phthalanes
EP1370545A4 (en) * 2001-03-09 2005-03-16 Ranbaxy Lab Ltd PROCESS FOR THE PREPARATION OF CITALOPRAM
US6967259B2 (en) * 2001-09-24 2005-11-22 Pharmachem Technologies Limited Process for the preparation of Citalopram intermediate
BR0213949A (pt) * 2001-11-08 2004-08-31 Sepracor Inc Métodos para o tratamento de depressão e outros distúrbios do snc utilizando metabólitos desmetila e didesmetila de citalopram enanciomericamente enriquecidos
AU2003222435A1 (en) * 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
KR20050086560A (ko) * 2002-11-15 2005-08-30 아크조 노벨 엔.브이. 지방 니트릴용 정제/탈색 처리 방법
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en) * 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
WO2005042473A1 (en) * 2003-10-28 2005-05-12 Wockhardt Limited Improved process for the manufacture of citalopram hydrobromide
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
CN114763343A (zh) * 2021-01-14 2022-07-19 浙江华海药业股份有限公司 一种西酞普兰或s-西酞普兰的纯化方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE536169C (de) * 1926-08-21 1931-10-20 British Dyestuffs Corp Ltd Verfahren zur Gewinnung von tertiaeren aromatischen Aminen aus ihren Gemischen mit sekundaeren und primaeren aromatischen Aminen
US1992111A (en) * 1931-06-20 1935-02-19 Du Pont Separation of secondary and tertiary amines
DE1032261B (de) * 1955-03-08 1958-06-19 Leda Chemicals Ltd Verfahren zur Abtrennung sekundaerer Amine aus einer primaeres und sekundaeres Amin enthaltenden Mischung
GB1143702A (no) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
US4302399A (en) * 1978-09-28 1981-11-24 Dynapol Acetylation of crude reaction products containing polymeric colorants
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
US4943591A (en) 1984-10-17 1990-07-24 Glaxo Group Limited Dichloroaniline derivatives
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
DK213290D0 (da) * 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
AU4655597A (en) * 1997-06-30 1999-01-19 Beloit Technologies, Inc. Method and apparatus for the high speed application of coating to a traveling paper web
JP3526581B2 (ja) * 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CA2291072C (en) * 1997-11-11 2002-08-20 H. Lundbeck A/S Method for the preparation of citalopram
DK1123284T3 (da) 1998-10-20 2003-04-28 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
SI1140886T1 (en) 1998-12-23 2003-08-31 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991486A1 (it) * 1999-07-06 2001-01-06 Vis Farmaceutici S P A Processo per la sintesi di citalopram
SK287139B6 (sk) 1999-10-25 2010-01-07 H. Lundbeck A/S Spôsob prípravy citalopramu
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
CA2359810C (en) 2000-12-28 2002-11-05 H. Lundbeck A/S Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
AT4367U1 (de) 2001-06-25
DK1181713T3 (da) 2005-01-31
PL205724B1 (pl) 2010-05-31
BG65131B1 (bg) 2007-03-30
GB0105983D0 (en) 2001-05-02
KR100439329B1 (ko) 2004-07-07
BE1013212A6 (fr) 2001-10-02
MXPA01013151A (es) 2002-08-12
BR0106272A (pt) 2004-06-15
HUP0102817A2 (hu) 2001-12-28
JP3798982B2 (ja) 2006-07-19
AU2001100405A4 (en) 2001-11-01
US20020120005A1 (en) 2002-08-29
IS5883A (is) 2001-06-20
NL1017525C1 (nl) 2001-04-26
EP1462447A2 (en) 2004-09-29
FI20011577A0 (fi) 2001-07-26
HRP20020004A2 (en) 2003-04-30
SK284428B6 (sk) 2005-04-01
HU0102817D0 (en) 2001-09-28
NO20011271D0 (no) 2001-03-13
KR20020065345A (ko) 2002-08-13
CA2360303A1 (en) 2001-06-28
ES2170732B2 (es) 2003-09-16
NZ516298A (en) 2002-12-20
NO312462B1 (no) 2002-05-13
IES20010254A2 (en) 2002-03-06
EP1181713B1 (en) 2004-09-29
ZA200110179B (en) 2002-12-11
PT1181713E (pt) 2005-02-28
FR2812877B1 (fr) 2003-04-04
EP1181713A2 (en) 2002-02-27
DE60105926T2 (de) 2005-11-24
EA200200018A1 (ru) 2002-04-25
JP2003517484A (ja) 2003-05-27
CN1366525A (zh) 2002-08-28
US6455710B1 (en) 2002-09-24
SI1181713T1 (en) 2005-02-28
CH691535A5 (de) 2001-08-15
ITMI20010602A0 (it) 2001-03-22
EP1462447A3 (en) 2004-11-17
BG106203A (en) 2002-08-30
SE0103045D0 (sv) 2001-09-14
GR1003874B (el) 2002-04-24
SE517623C2 (sv) 2002-06-25
IL147226A (en) 2006-04-10
NL1018360C1 (nl) 2001-10-04
HK1048812B (zh) 2007-06-01
ES2228824T3 (es) 2005-04-16
SK18482001A3 (sk) 2002-05-09
ES2170732A1 (es) 2002-08-01
ATE277920T1 (de) 2004-10-15
PL353398A1 (en) 2003-11-17
FI108639B (fi) 2002-02-28
BE1013213A6 (fr) 2001-10-02
ITMI20010602A1 (it) 2002-09-22
WO2001045483A3 (en) 2001-12-27
AU2001100405B4 (en) 2002-03-21
HU0101029D0 (en) 2001-05-28
GB2357763A (en) 2001-07-04
EA003581B1 (ru) 2003-06-26
IS2060B (is) 2005-11-15
AU3920101A (en) 2001-07-03
CN1282648C (zh) 2006-11-01
CZ2001890A3 (cs) 2002-08-14
SG167655A1 (en) 2011-01-28
CA2360303C (en) 2003-08-12
WO2001045483A2 (en) 2001-06-28
DE10112829C1 (de) 2002-07-25
TR200201166T1 (tr) 2002-10-21
FI20010500A0 (fi) 2001-03-13
SK286283B6 (sk) 2008-06-06
DE60105926D1 (de) 2004-11-04
HUP0102817A3 (en) 2003-07-28
AR030056A1 (es) 2003-08-13
SE0103045L (sv) 2002-06-23
IL147226A0 (en) 2002-08-14
FR2812877A1 (fr) 2002-02-15
CZ292200B6 (cs) 2003-08-13
UA71634C2 (uk) 2004-12-15
GB2357763B (en) 2002-01-16
HK1048812A1 (en) 2003-04-17

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