NO20030515L - Fremgangsmåte for fremstilling av dinapsolin - Google Patents

Fremgangsmåte for fremstilling av dinapsolin

Info

Publication number
NO20030515L
NO20030515L NO20030515A NO20030515A NO20030515L NO 20030515 L NO20030515 L NO 20030515L NO 20030515 A NO20030515 A NO 20030515A NO 20030515 A NO20030515 A NO 20030515A NO 20030515 L NO20030515 L NO 20030515L
Authority
NO
Norway
Prior art keywords
dinapsoline
preparation
Prior art date
Application number
NO20030515A
Other languages
English (en)
Other versions
NO20030515D0 (no
Inventor
Sing-Yuen Sit
Swanee Jacutin-Porte
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of NO20030515D0 publication Critical patent/NO20030515D0/no
Publication of NO20030515L publication Critical patent/NO20030515L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/18Ring systems of four or more rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO20030515A 2000-08-11 2003-02-03 Fremgangsmåte for fremstilling av dinapsolin NO20030515L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22496800P 2000-08-11 2000-08-11
PCT/US2001/025265 WO2002013827A1 (en) 2000-08-11 2001-08-10 Process for the preparation of dinapsoline

Publications (2)

Publication Number Publication Date
NO20030515D0 NO20030515D0 (no) 2003-02-03
NO20030515L true NO20030515L (no) 2003-03-31

Family

ID=22842980

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030515A NO20030515L (no) 2000-08-11 2003-02-03 Fremgangsmåte for fremstilling av dinapsolin

Country Status (12)

Country Link
US (1) US6645975B1 (no)
EP (1) EP1320367A4 (no)
JP (1) JP2004506014A (no)
KR (1) KR20030027020A (no)
CN (1) CN1473045A (no)
AU (2) AU2001288242B2 (no)
BR (1) BR0113170A (no)
CA (1) CA2417807A1 (no)
MX (1) MXPA03001272A (no)
NO (1) NO20030515L (no)
NZ (1) NZ524212A (no)
WO (1) WO2002013827A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60220800D1 (de) 2001-08-10 2007-08-02 Purdue Research Foundation Chirales dinapsolin
FR3017868A1 (fr) * 2014-02-21 2015-08-28 Servier Lab Derives d'isoquinoleine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JOP20200114A1 (ar) 2017-11-24 2020-05-17 H Lundbeck As عقاقير أولية جديدة من الكاتيكولامين للاستخدام في علاج مرض باركنسون
US11130775B2 (en) 2019-05-20 2021-09-28 H. Lundbeck A/S Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11111263B2 (en) 2019-05-20 2021-09-07 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11104697B2 (en) 2019-05-20 2021-08-31 H. Lundbeck A/S Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
US11168056B2 (en) 2019-05-20 2021-11-09 H. Lundbeck A/S Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK297275A (da) * 1974-08-07 1976-02-08 Aspro Nicholas Ltd Isoquinolinderivater
CA1033358A (en) * 1974-09-03 1978-06-20 Ayerst, Mckenna And Harrison Limited Benzo(4,5)(1,2,3-ij)isoquinolines and process therefor
IL122974A (en) * 1995-08-18 2000-11-21 Purdue Research Foundation Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them
EP0883609A1 (en) * 1996-02-23 1998-12-16 Pharmeco Laboratories, Inc. Selective d1 dopamine receptor agonists and partial agonists/antagonists

Also Published As

Publication number Publication date
US6645975B1 (en) 2003-11-11
AU8824201A (en) 2002-02-25
BR0113170A (pt) 2004-01-06
AU2001288242B2 (en) 2005-11-17
WO2002013827A1 (en) 2002-02-21
EP1320367A1 (en) 2003-06-25
NO20030515D0 (no) 2003-02-03
MXPA03001272A (es) 2004-04-02
JP2004506014A (ja) 2004-02-26
EP1320367A4 (en) 2007-01-17
CA2417807A1 (en) 2002-02-21
NZ524212A (en) 2004-07-30
CN1473045A (zh) 2004-02-04
KR20030027020A (ko) 2003-04-03

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application