DE60220800D1 - Chirales dinapsolin - Google Patents
Chirales dinapsolinInfo
- Publication number
- DE60220800D1 DE60220800D1 DE60220800T DE60220800T DE60220800D1 DE 60220800 D1 DE60220800 D1 DE 60220800D1 DE 60220800 T DE60220800 T DE 60220800T DE 60220800 T DE60220800 T DE 60220800T DE 60220800 D1 DE60220800 D1 DE 60220800D1
- Authority
- DE
- Germany
- Prior art keywords
- dinapsolin
- chiral
- napth
- isoquinoline
- tetrahydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31161401P | 2001-08-10 | 2001-08-10 | |
PCT/US2002/025267 WO2003013532A1 (en) | 2001-08-10 | 2002-08-08 | Chiral dinapsoline |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60220800D1 true DE60220800D1 (de) | 2007-08-02 |
Family
ID=23207674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60220800T Expired - Lifetime DE60220800D1 (de) | 2001-08-10 | 2002-08-08 | Chirales dinapsolin |
Country Status (6)
Country | Link |
---|---|
US (1) | US7091212B2 (de) |
EP (1) | EP1414457B1 (de) |
JP (1) | JP2005504758A (de) |
AT (1) | ATE365040T1 (de) |
DE (1) | DE60220800D1 (de) |
WO (1) | WO2003013532A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112019014981A2 (pt) | 2017-11-24 | 2020-04-07 | H Lundbeck As | composto, sal farmaceuticamente aceitável, uso dos mesmos e composição farmacêutica |
US11104697B2 (en) | 2019-05-20 | 2021-08-31 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11168056B2 (en) | 2019-05-20 | 2021-11-09 | H. Lundbeck A/S | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol |
US11111263B2 (en) | 2019-05-20 | 2021-09-07 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11130775B2 (en) | 2019-05-20 | 2021-09-28 | H. Lundbeck A/S | Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5047536A (en) * | 1989-03-17 | 1991-09-10 | Purdue Research Foundation | Hexahydrobenzo(A)phenanthridine compounds |
DE69334206D1 (de) * | 1992-05-26 | 2008-04-03 | Purdue Research Foundation | Substituierte hexahydrobenzo(a) phenanthridine |
CA2195239A1 (en) * | 1994-07-15 | 1996-02-01 | David E. Nichols | Optically active isomers of dihydrexidine and its substituted analogs |
JPH11508997A (ja) | 1995-07-05 | 1999-08-03 | モトローラ・インコーポレイテッド | 共形電源 |
WO1997006798A2 (en) | 1995-08-12 | 1997-02-27 | Smithkline Beecham Plc | Pharmaceutical formulations |
IL122974A (en) | 1995-08-18 | 2000-11-21 | Purdue Research Foundation | Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them |
AU8824201A (en) * | 2000-08-11 | 2002-02-25 | Bristol Myers Squibb Co | Process for the preparation of dinapsoline |
-
2002
- 2002-08-08 US US10/398,116 patent/US7091212B2/en not_active Expired - Fee Related
- 2002-08-08 DE DE60220800T patent/DE60220800D1/de not_active Expired - Lifetime
- 2002-08-08 EP EP02765964A patent/EP1414457B1/de not_active Expired - Lifetime
- 2002-08-08 JP JP2003518541A patent/JP2005504758A/ja active Pending
- 2002-08-08 AT AT02765964T patent/ATE365040T1/de not_active IP Right Cessation
- 2002-08-08 WO PCT/US2002/025267 patent/WO2003013532A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP1414457A4 (de) | 2004-12-29 |
JP2005504758A (ja) | 2005-02-17 |
EP1414457A1 (de) | 2004-05-06 |
WO2003013532A1 (en) | 2003-02-20 |
ATE365040T1 (de) | 2007-07-15 |
US20040063741A1 (en) | 2004-04-01 |
US7091212B2 (en) | 2006-08-15 |
EP1414457B1 (de) | 2007-06-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |