MXPA03001272A - Procedimiento para la preparacion de dinapsolina. - Google Patents
Procedimiento para la preparacion de dinapsolina.Info
- Publication number
- MXPA03001272A MXPA03001272A MXPA03001272A MXPA03001272A MXPA03001272A MX PA03001272 A MXPA03001272 A MX PA03001272A MX PA03001272 A MXPA03001272 A MX PA03001272A MX PA03001272 A MXPA03001272 A MX PA03001272A MX PA03001272 A MXPA03001272 A MX PA03001272A
- Authority
- MX
- Mexico
- Prior art keywords
- preparation
- dinapsoline
- fornula
- compounds
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La presente invencion se refiere a un procedimiento novedoso para la preparacion de compuestos de formula (IX); (ver formula) en donde R1, R2, R4, R5, R6 y A son como se definen en la presente, y a ciertas derivaciones de la formula (IX) que son utiles para el tratamiento de trastornos del movimiento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22496800P | 2000-08-11 | 2000-08-11 | |
PCT/US2001/025265 WO2002013827A1 (en) | 2000-08-11 | 2001-08-10 | Process for the preparation of dinapsoline |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03001272A true MXPA03001272A (es) | 2004-04-02 |
Family
ID=22842980
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03001272A MXPA03001272A (es) | 2000-08-11 | 2001-08-10 | Procedimiento para la preparacion de dinapsolina. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6645975B1 (es) |
EP (1) | EP1320367A4 (es) |
JP (1) | JP2004506014A (es) |
KR (1) | KR20030027020A (es) |
CN (1) | CN1473045A (es) |
AU (2) | AU2001288242B2 (es) |
BR (1) | BR0113170A (es) |
CA (1) | CA2417807A1 (es) |
MX (1) | MXPA03001272A (es) |
NO (1) | NO20030515L (es) |
NZ (1) | NZ524212A (es) |
WO (1) | WO2002013827A1 (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7091212B2 (en) | 2001-08-10 | 2006-08-15 | Purdue Research Foundation | Chiral dinapsoline |
FR3017868A1 (fr) | 2014-02-21 | 2015-08-28 | Servier Lab | Derives d'isoquinoleine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
PE20211290A1 (es) | 2017-11-24 | 2021-07-20 | H Lundbeck As | Nuevos profarmacos de catecolamina para uso en el tratamiento de la enfermedad del parkinson |
US11168056B2 (en) | 2019-05-20 | 2021-11-09 | H. Lundbeck A/S | Process for the manufacturing of (6aR,10aR)-7-propyl-6,6a,7,8,9,10,10a,11-octahydro-[1,3]dioxolo[4′,5′:5,6]benzo[1,2-G]quinoline and (4aR,10aR)-1-propyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[G]quinoline-6,7-diol |
US11111263B2 (en) | 2019-05-20 | 2021-09-07 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11130775B2 (en) | 2019-05-20 | 2021-09-28 | H. Lundbeck A/S | Solid forms of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4aR,10aR)-7-hydroxy-1-propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
US11104697B2 (en) | 2019-05-20 | 2021-08-31 | H. Lundbeck A/S | Process for the manufacture of (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((4AR,10AR)-7-hydroxy-1- propyl-1,2,3,4,4A,5,10,10A-octahydrobenzo[g]quinolin-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK297275A (da) * | 1974-08-07 | 1976-02-08 | Aspro Nicholas Ltd | Isoquinolinderivater |
CA1033358A (en) * | 1974-09-03 | 1978-06-20 | Ayerst, Mckenna And Harrison Limited | Benzo(4,5)(1,2,3-ij)isoquinolines and process therefor |
ES2169257T3 (es) * | 1995-08-18 | 2002-07-01 | Purdue Research Foundation | Nuevas isoquinolinas fusionadas como ligandos del receptor de la dopamina. |
JP2000506832A (ja) * | 1996-02-23 | 2000-06-06 | ファーム―エコ ラボラトリーズ,インコーポレイテッド | 選択的なd1ドーパミンレセプターアゴニスト及び部分的アゴニスト/アンタゴニスト |
-
2001
- 2001-08-10 MX MXPA03001272A patent/MXPA03001272A/es not_active Application Discontinuation
- 2001-08-10 CN CNA018166903A patent/CN1473045A/zh active Pending
- 2001-08-10 CA CA002417807A patent/CA2417807A1/en not_active Abandoned
- 2001-08-10 EP EP01967963A patent/EP1320367A4/en not_active Withdrawn
- 2001-08-10 NZ NZ524212A patent/NZ524212A/en unknown
- 2001-08-10 AU AU2001288242A patent/AU2001288242B2/en not_active Ceased
- 2001-08-10 AU AU8824201A patent/AU8824201A/xx active Pending
- 2001-08-10 BR BR0113170-2A patent/BR0113170A/pt not_active Application Discontinuation
- 2001-08-10 WO PCT/US2001/025265 patent/WO2002013827A1/en not_active Application Discontinuation
- 2001-08-10 KR KR10-2003-7001975A patent/KR20030027020A/ko not_active Application Discontinuation
- 2001-08-10 JP JP2002518970A patent/JP2004506014A/ja not_active Withdrawn
- 2001-08-10 US US10/343,037 patent/US6645975B1/en not_active Expired - Fee Related
-
2003
- 2003-02-03 NO NO20030515A patent/NO20030515L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2001288242B2 (en) | 2005-11-17 |
NO20030515L (no) | 2003-03-31 |
US6645975B1 (en) | 2003-11-11 |
BR0113170A (pt) | 2004-01-06 |
CA2417807A1 (en) | 2002-02-21 |
AU8824201A (en) | 2002-02-25 |
JP2004506014A (ja) | 2004-02-26 |
EP1320367A1 (en) | 2003-06-25 |
WO2002013827A1 (en) | 2002-02-21 |
CN1473045A (zh) | 2004-02-04 |
KR20030027020A (ko) | 2003-04-03 |
NZ524212A (en) | 2004-07-30 |
EP1320367A4 (en) | 2007-01-17 |
NO20030515D0 (no) | 2003-02-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB0325956D0 (en) | Novel compounds | |
MY135841A (en) | Novel benzodioxoles | |
NO20071642L (no) | N-Benzensulfonylsubstituerte anilino-pyrimidinanaloger | |
IL159418A0 (en) | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | |
YU63703A (sh) | 6-supstituisani pirido-pirimidini | |
YU78303A (sh) | Postupak za dobijanje 1,3-supstituisanih indena i azapolicikličnih jedinjenja sa pripojenim arilom | |
HK1155146A1 (zh) | 作為藥物活性劑的茚衍生物 | |
PL371127A1 (en) | 6-aminomorphinane derivatives, method for the production and use thereof | |
MXPA03011954A (es) | Nuevos derivados de acido sulfonico. | |
MXPA04006041A (es) | Antivirales de piridoquinoxalina. | |
WO2005060693A3 (en) | 9-desoxoerythromycin compounds as prokinetic agents | |
GB0322510D0 (en) | Novel compounds | |
NO20062152L (no) | Fremstilling av 3-azabicyklo [3.1.0.]heksanderivater | |
MXPA03001272A (es) | Procedimiento para la preparacion de dinapsolina. | |
SE0101082D0 (sv) | Novel use | |
MXPA04003544A (es) | Benzotriazepinas como ligandos del receptor de gastrina y colecistocinina. | |
TR200302288T2 (tr) | Terapi için yeni bileşikler ve metotlar. | |
MXPA04005151A (es) | Compuestos terapeuticos. | |
PT1206452E (pt) | Processo de preparacao de compostos benzoper-hidroisoindole | |
MXPA03010498A (es) | Proceso para la preparacion de imipenem. | |
ATE419238T1 (de) | Arylsulfanyl und heteroarylsulfanyl-derivate zur behandlung von schmerz | |
MXPA04004980A (es) | Antagonistas del receptor ccr-3. | |
IL156768A0 (en) | Process for preparing (+/-) trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine | |
DK0703232T3 (da) | 2,3-Dihydro-1H-isoindolderivater, fremgangsmåde til deres fremstilling og deres anvendelse som hæmmere af serotoningenoptagelsen | |
YU22802A (sh) | Izonipekotamidi za lečenje poremećaja nastalih posredstvom integrina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |