MXPA04005151A - Compuestos terapeuticos. - Google Patents

Compuestos terapeuticos.

Info

Publication number
MXPA04005151A
MXPA04005151A MXPA04005151A MXPA04005151A MXPA04005151A MX PA04005151 A MXPA04005151 A MX PA04005151A MX PA04005151 A MXPA04005151 A MX PA04005151A MX PA04005151 A MXPA04005151 A MX PA04005151A MX PA04005151 A MXPA04005151 A MX PA04005151A
Authority
MX
Mexico
Prior art keywords
compounds
therapeutic compounds
formula
well
provides
Prior art date
Application number
MXPA04005151A
Other languages
English (en)
Inventor
Fu Jian-Min
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of MXPA04005151A publication Critical patent/MXPA04005151A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0468—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K51/047—Benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Abstract

La presente invencion proporciona compuestos de formula (I):(ver formula I)en donde X, R1, R2, R3, R4, R5 y R6 tienen cualquiera de los valores definidos en la especificacion, asi como tambien composiciones farmaceuticas que comprenden los compuestos. La invencion tambien proporciona metodos terapeuticos asi como tambien procesos e intermediarios utiles para prepara compuestos de Formula (I).
MXPA04005151A 2001-11-28 2002-11-26 Compuestos terapeuticos. MXPA04005151A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33401201P 2001-11-28 2001-11-28
PCT/US2002/037715 WO2003045940A2 (en) 2001-11-28 2002-11-26 Benzazepine derivatives and their use as 5-ht ligands

Publications (1)

Publication Number Publication Date
MXPA04005151A true MXPA04005151A (es) 2004-08-11

Family

ID=23305178

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04005151A MXPA04005151A (es) 2001-11-28 2002-11-26 Compuestos terapeuticos.

Country Status (8)

Country Link
US (1) US6861420B2 (es)
EP (1) EP1451176A2 (es)
JP (1) JP2005535560A (es)
AU (1) AU2002346507A1 (es)
BR (1) BR0214529A (es)
CA (1) CA2468010A1 (es)
MX (1) MXPA04005151A (es)
WO (1) WO2003045940A2 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2475254A1 (en) * 2002-03-04 2003-09-18 Pharmacia & Upjohn Company Pyridinyloxy derivatives as 5-ht receptor ligands
TW200510324A (en) * 2003-08-11 2005-03-16 Lilly Co Eli 6-(2,2,2-trifluoroethylamino)-7-chiloro-2, 3, 4, 5-tetrahydro-1h-benzo[d]azepine as a 5-ht2c receptor agonist
CN1934088A (zh) 2004-02-25 2007-03-21 伊莱利利公司 作为5－HT<sub>2c</sub>受体激动剂的6－取代的2,3,4,5－四氢－1H－苯并[d]氮杂䓬
WO2006117218A2 (en) * 2005-05-04 2006-11-09 Charite Universitätsmedizin - Berlin Serotonin-transport-protein binding radiopharmaceutical for the production of a diagnostic medicament for the diagnosis of headache
EP1728520A1 (de) * 2005-05-04 2006-12-06 Charité - Universitätsmedizin Berlin Verwendung von spezifisch an das Serotonin-Transport-Protein (SERT) bindenden Radiopharmaka zur Herstellung eines Diagnostikums zur Untersuchung von Kopfschmerzerkrankungen
WO2007028083A2 (en) 2005-09-01 2007-03-08 Eli Lilly And Company 6-arylalkylamino- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
US7981882B2 (en) 2005-09-01 2011-07-19 Eli Lilly And Company 6-N-linked heterocycle-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists
EP1924560B1 (en) * 2005-09-01 2009-08-05 Eli Lilly And Company 6-substituted- 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
JP5237810B2 (ja) 2005-09-01 2013-07-17 イーライ リリー アンド カンパニー ５−ＨＴ２Ｃ受容体アゴニストとしての６−置換された２，３，４，５−テトラヒドロ−１Ｈ−ベンゾ［ｄ］アゼピン

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132311A (en) * 1990-06-27 1992-07-21 G. D. Searle & Co. Cyanoquanidine type III antiarrhythmic agents and use
GB9612885D0 (en) 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
GB9612883D0 (en) 1996-06-20 1996-08-21 Smithkline Beecham Plc Novel compounds
AU2001264376A1 (en) * 2000-06-15 2001-12-24 Chaconne Nsi Co., Ltd. Urea derivative useful as an anti-cancer agent and process for preparing same

Also Published As

Publication number Publication date
CA2468010A1 (en) 2003-06-05
WO2003045940A2 (en) 2003-06-05
BR0214529A (pt) 2006-05-30
US6861420B2 (en) 2005-03-01
WO2003045940A3 (en) 2003-09-12
AU2002346507A1 (en) 2003-06-10
AU2002346507A8 (en) 2003-06-10
EP1451176A2 (en) 2004-09-01
JP2005535560A (ja) 2005-11-24
US20030149024A1 (en) 2003-08-07

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