NO20062152L - Fremstilling av 3-azabicyklo [3.1.0.]heksanderivater - Google Patents

Fremstilling av 3-azabicyklo [3.1.0.]heksanderivater

Info

Publication number
NO20062152L
NO20062152L NO20062152A NO20062152A NO20062152L NO 20062152 L NO20062152 L NO 20062152L NO 20062152 A NO20062152 A NO 20062152A NO 20062152 A NO20062152 A NO 20062152A NO 20062152 L NO20062152 L NO 20062152L
Authority
NO
Norway
Prior art keywords
azabicyclo
preparation
hexane derivatives
formula
compound
Prior art date
Application number
NO20062152A
Other languages
English (en)
Inventor
Derek Lawrence Tickner
Jotham Wadsworth Coe
Stanton Furst Mchardy
John Anthony Ragan
Brian Clement Vanderplas
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20062152L publication Critical patent/NO20062152L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Foreliggende oppfinnelse angår en ny og forbedret reduktiv amineringsfremgangsmåte for fremstilling av 3-azabisyklo [3.1.0] hexan derivater med formel I som innbefatter omsetning av en forbindelse med formel II med en forbindelse med formel III
NO20062152A 2003-10-16 2006-05-12 Fremstilling av 3-azabicyklo [3.1.0.]heksanderivater NO20062152L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51188903P 2003-10-16 2003-10-16
PCT/IB2004/003261 WO2005037790A1 (en) 2003-10-16 2004-10-06 Preparation of 3-azabicyclo [3.1.0] hexane derivatives

Publications (1)

Publication Number Publication Date
NO20062152L true NO20062152L (no) 2006-05-12

Family

ID=34465290

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062152A NO20062152L (no) 2003-10-16 2006-05-12 Fremstilling av 3-azabicyklo [3.1.0.]heksanderivater

Country Status (17)

Country Link
US (1) US7129263B2 (no)
EP (1) EP1675829A1 (no)
JP (1) JP2007508367A (no)
KR (1) KR20060096038A (no)
CN (1) CN1867548A (no)
AR (1) AR046592A1 (no)
AU (1) AU2004281229A1 (no)
BR (1) BRPI0415459A (no)
CA (1) CA2540860A1 (no)
CO (1) CO5680416A2 (no)
IL (1) IL174596A0 (no)
MX (1) MXPA06004278A (no)
NO (1) NO20062152L (no)
RU (1) RU2006112576A (no)
TW (1) TW200524866A (no)
WO (1) WO2005037790A1 (no)
ZA (1) ZA200601964B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006510673A (ja) 2002-12-10 2006-03-30 ワイス プラスミノゲンアクティベータインヒビター１（ｐａｉ−１）のインヒビターとしての、アリール、アリールオキシ、および、アルキルオキシ置換１ｈ−インドール−３−イルグリオキシル酸誘導体
KR20060095865A (ko) * 2003-10-14 2006-09-04 화이자 프로덕츠 인크. 글리신 수송 억제제로서의 비시클릭 [3.1.0] 유도체
WO2008075162A2 (en) * 2006-12-15 2008-06-26 Pfizer Limited Selective mu opioid receptor antagonists for the treatment of female sexual dysfunction
WO2012042539A2 (en) 2010-09-28 2012-04-05 Panacea Biotec Ltd Novel bicyclic compounds
EP2919788A4 (en) 2012-11-14 2016-05-25 Univ Johns Hopkins METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
KR102305244B1 (ko) 2013-11-20 2021-09-27 우베 고산 가부시키가이샤 신규 3-아자비사이클로[3.1.0]헥산 유도체 및 그 의약 용도
JP6087035B1 (ja) * 2015-05-20 2017-03-01 株式会社三和化学研究所 新規３−アザビシクロ［３．１．０］ヘキサン誘導体の塩の結晶及びその医薬用途
US20210051958A1 (en) * 2018-03-05 2021-02-25 E. I. Du Pont De Nemours And Company Process and intermidiates for the preparation of certain mesoionic pesticides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
BR0213464A (pt) * 2001-10-22 2004-11-09 Pfizer Prod Inc Derivados de 3-azabiciclo[3.1.0]hexano como antagonistas receptores de opióide

Also Published As

Publication number Publication date
CO5680416A2 (es) 2006-09-29
TW200524866A (en) 2005-08-01
IL174596A0 (en) 2006-08-20
EP1675829A1 (en) 2006-07-05
CN1867548A (zh) 2006-11-22
US7129263B2 (en) 2006-10-31
BRPI0415459A (pt) 2006-12-19
AR046592A1 (es) 2005-12-14
AU2004281229A1 (en) 2005-04-28
JP2007508367A (ja) 2007-04-05
ZA200601964B (en) 2007-04-25
MXPA06004278A (es) 2006-06-28
WO2005037790A1 (en) 2005-04-28
RU2006112576A (ru) 2006-08-27
KR20060096038A (ko) 2006-09-05
US20050113437A1 (en) 2005-05-26
CA2540860A1 (en) 2005-04-28

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