DK1411116T3 - Peptidsyntasegen, peptidsyntase samt fremgangsmåde til fremstilling af dipeptid - Google Patents

Peptidsyntasegen, peptidsyntase samt fremgangsmåde til fremstilling af dipeptid

Info

Publication number
DK1411116T3
DK1411116T3 DK02751741T DK02751741T DK1411116T3 DK 1411116 T3 DK1411116 T3 DK 1411116T3 DK 02751741 T DK02751741 T DK 02751741T DK 02751741 T DK02751741 T DK 02751741T DK 1411116 T3 DK1411116 T3 DK 1411116T3
Authority
DK
Denmark
Prior art keywords
peptide synthase
dipeptide
amino acid
producing
culture
Prior art date
Application number
DK02751741T
Other languages
English (en)
Inventor
Naoto Tonouchi
Sonoko Suzuki
Kenzo Yokozeki
Hiroyuki Nozaki
Masakazu Sugiyama
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Application granted granted Critical
Publication of DK1411116T3 publication Critical patent/DK1411116T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02751741T 2001-07-26 2002-07-26 Peptidsyntasegen, peptidsyntase samt fremgangsmåde til fremstilling af dipeptid DK1411116T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2001226568 2001-07-26
JP2001310547 2001-10-05
PCT/JP2002/007635 WO2003010307A1 (en) 2001-07-26 2002-07-26 Peptide synthase gene, peptide synthase and process for producing dipeptide

Publications (1)

Publication Number Publication Date
DK1411116T3 true DK1411116T3 (da) 2008-08-25

Family

ID=26619355

Family Applications (2)

Application Number Title Priority Date Filing Date
DK08000584.6T DK1911839T3 (da) 2001-07-26 2002-07-26 Peptiddannende enzymgen, peptiddannende enzym og dipeptidproducerende fremgangsmåde
DK02751741T DK1411116T3 (da) 2001-07-26 2002-07-26 Peptidsyntasegen, peptidsyntase samt fremgangsmåde til fremstilling af dipeptid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK08000584.6T DK1911839T3 (da) 2001-07-26 2002-07-26 Peptiddannende enzymgen, peptiddannende enzym og dipeptidproducerende fremgangsmåde

Country Status (9)

Country Link
US (5) US7037673B2 (da)
EP (4) EP1411116B1 (da)
JP (3) JP4239819B2 (da)
KR (2) KR100635803B1 (da)
CN (4) CN100422207C (da)
DE (1) DE60226243T2 (da)
DK (2) DK1911839T3 (da)
RU (3) RU2280077C2 (da)
WO (3) WO2003010187A1 (da)

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EP1541688B1 (en) 2002-07-26 2012-09-05 Ajinomoto Co., Inc. Peptide synthase gene
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US20050148048A1 (en) * 2003-11-27 2005-07-07 Kyowa Hakko Kogyo Co., Ltd. Process for producing dipeptides
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CN1320099C (zh) * 2005-02-04 2007-06-06 南京工业大学 利用北里孢菌PL6－3制备ε－聚赖氨酸及其盐的方法
CN101151369B (zh) * 2005-03-29 2017-02-15 协和发酵生化株式会社 二肽的结晶及其制备方法
WO2007074858A1 (ja) * 2005-12-27 2007-07-05 Kyowa Hakko Kogyo Co., Ltd. ジペプチドの製造法
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RU2470996C2 (ru) * 2007-01-11 2012-12-27 ДАНИСКО ЮЭс ИНК., ДЖЕНЕНКОР ДИВИЖН Способ получения белка
CN101715484B (zh) 2007-04-06 2014-02-19 协和发酵生化株式会社 二肽的制造方法
US8104191B2 (en) 2008-07-31 2012-01-31 Electrolux Home Products, Inc. Laundry dryer providing moisture application during tumbling and reduced airflow
US8946164B2 (en) 2010-04-07 2015-02-03 Kyoto University Bioactive peptide
KR101144987B1 (ko) * 2010-04-12 2012-05-11 목원대학교 산학협력단 크리세오박테리움 ｆｂｆ-7 균주 배양물 및 이를 함유하는 뿌리혹선충 방제용 조성물
RU2012129311A (ru) 2012-07-11 2014-01-20 Закрытое акционерное общество " Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Днк, кодирующая дипептид-синтезирующий фермер (варианты), бактерия рода escherichia и способ получения дипептидов с ее использованием
CN103114068B (zh) * 2013-03-15 2014-06-11 江苏南资环保科技有限公司 一株哌嗪降解无色杆菌菌mbpq-cg及其应用
RU2560980C2 (ru) * 2013-07-11 2015-08-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") ДНК, КОДИРУЮЩАЯ ДИПЕПТИД-СИНТЕЗИРУЮЩИЙ ФЕРМЕНТ (ВАРИАНТЫ), БАКТЕРИЯ РОДА Escherichia И СПОСОБ ПОЛУЧЕНИЯ ДИПЕПТИДОВ С ЕЕ ИСПОЛЬЗОВАНИЕМ
CN104480172A (zh) * 2014-11-19 2015-04-01 江南大学 一种利用重组大肠杆菌生产l-丙氨酰-l-谷氨酰胺的方法
JP6667781B2 (ja) 2015-03-02 2020-03-18 国立大学法人京都大学 ペプチド
CN106565822A (zh) * 2016-10-17 2017-04-19 湖北泓肽生物科技有限公司 手性l‑丙氨酰‑苯丙氨酸的制备方法
ES2908806T3 (es) * 2016-12-30 2022-05-04 Innobio Corporation Ltd Gen que codifica la enzima biosintética del dipéptido de alanil-glutamina y aplicación del mismo
FR3076992B1 (fr) 2018-01-23 2022-10-14 Samirath Adeyendju Akanke Alli Dispositif de protection vulvaire, kit de protection vulvaire et anale et procede d'installation d'une telle protection
CN113302310B (zh) * 2018-12-18 2024-05-03 帕西昂奥地利有限两合公司 单步生物催化酰胺化

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Also Published As

Publication number Publication date
US20070042459A1 (en) 2007-02-22
KR20040026658A (ko) 2004-03-31
EP1411062A1 (en) 2004-04-21
JPWO2003010187A1 (ja) 2004-11-18
EP1911839B1 (en) 2011-10-26
KR100635803B1 (ko) 2006-10-19
JP4289151B2 (ja) 2009-07-01
EP1411062A4 (en) 2006-09-13
WO2003010187A1 (fr) 2003-02-06
KR20040023686A (ko) 2004-03-18
WO2003010307A1 (en) 2003-02-06
WO2003010189A1 (en) 2003-02-06
CN1529712A (zh) 2004-09-15
JPWO2003010307A1 (ja) 2004-11-18
US20040137558A1 (en) 2004-07-15
CN101982546A (zh) 2011-03-02
US20070048838A1 (en) 2007-03-01
CN1558947A (zh) 2004-12-29
JPWO2003010189A1 (ja) 2004-11-18
EP1411116A1 (en) 2004-04-21
US20050054067A1 (en) 2005-03-10
CN100422207C (zh) 2008-10-01
RU2004105652A (ru) 2005-04-27
US7618796B2 (en) 2009-11-17
US7754466B2 (en) 2010-07-13
EP1911839A1 (en) 2008-04-16
EP1411060A1 (en) 2004-04-21
EP1411060A4 (en) 2006-09-13
CN1535279A (zh) 2004-10-06
US7288388B2 (en) 2007-10-30
RU2316596C2 (ru) 2008-02-10
CN1268742C (zh) 2006-08-09
EP1411116B1 (en) 2008-04-23
JP4239819B2 (ja) 2009-03-18
RU2003137001A (ru) 2005-05-27
DK1911839T3 (da) 2011-12-05
DE60226243T2 (de) 2009-05-14
US7037673B2 (en) 2006-05-02
DE60226243D1 (de) 2008-06-05
US20050037453A1 (en) 2005-02-17
RU2280077C2 (ru) 2006-07-20
EP1411116A4 (en) 2005-08-24
RU2005138717A (ru) 2007-06-20
KR100602808B1 (ko) 2006-07-20
JP4273967B2 (ja) 2009-06-03
RU2279440C2 (ru) 2006-07-10

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