DK1911839T3 - Peptiddannende enzymgen, peptiddannende enzym og dipeptidproducerende fremgangsmåde - Google Patents
Peptiddannende enzymgen, peptiddannende enzym og dipeptidproducerende fremgangsmådeInfo
- Publication number
- DK1911839T3 DK1911839T3 DK08000584.6T DK08000584T DK1911839T3 DK 1911839 T3 DK1911839 T3 DK 1911839T3 DK 08000584 T DK08000584 T DK 08000584T DK 1911839 T3 DK1911839 T3 DK 1911839T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptide
- dipeptide
- forming enzyme
- amino acid
- producing method
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001226568 | 2001-07-26 | ||
JP2001310547 | 2001-10-05 | ||
EP02751741A EP1411116B1 (en) | 2001-07-26 | 2002-07-26 | Peptide synthase gene, peptide synthase and process for producing dipeptide |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1911839T3 true DK1911839T3 (da) | 2011-12-05 |
Family
ID=26619355
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08000584.6T DK1911839T3 (da) | 2001-07-26 | 2002-07-26 | Peptiddannende enzymgen, peptiddannende enzym og dipeptidproducerende fremgangsmåde |
DK02751741T DK1411116T3 (da) | 2001-07-26 | 2002-07-26 | Peptidsyntasegen, peptidsyntase samt fremgangsmåde til fremstilling af dipeptid |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02751741T DK1411116T3 (da) | 2001-07-26 | 2002-07-26 | Peptidsyntasegen, peptidsyntase samt fremgangsmåde til fremstilling af dipeptid |
Country Status (9)
Country | Link |
---|---|
US (5) | US7037673B2 (da) |
EP (4) | EP1411116B1 (da) |
JP (3) | JP4289151B2 (da) |
KR (2) | KR100635803B1 (da) |
CN (4) | CN1268742C (da) |
DE (1) | DE60226243T2 (da) |
DK (2) | DK1911839T3 (da) |
RU (3) | RU2279440C2 (da) |
WO (3) | WO2003010307A1 (da) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2279440C2 (ru) | 2001-07-26 | 2006-07-10 | Адзиномото Ко., Инк. | Способ получения l-аланил-l-глутамина |
EP2298908B1 (en) | 2002-07-26 | 2014-08-20 | Ajinomoto Co., Inc. | Novel peptide-forming enzyme gene |
WO2004011652A1 (ja) | 2002-07-26 | 2004-02-05 | Ajinomoto Co., Inc. | トリペプチド以上のペプチドの製造方法 |
JP2005040037A (ja) | 2003-07-25 | 2005-02-17 | Ajinomoto Co Inc | ジペプチドの製造方法、それに用いるペプチド生成酵素、およびペプチド生成酵素の製造方法 |
US20050106703A1 (en) * | 2003-11-05 | 2005-05-19 | Kyowa Hakko Kogyo Co., Ltd. | Microorganisms producing dipeptides and process for producing dipeptides using the microorganisms |
US20050148048A1 (en) * | 2003-11-27 | 2005-07-07 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing dipeptides |
US20070128687A1 (en) * | 2003-11-28 | 2007-06-07 | Hajime Ikeda | Process for producing dipeptides |
JP2005168405A (ja) * | 2003-12-11 | 2005-06-30 | Ajinomoto Co Inc | ジペプチドの製造方法 |
JP4507618B2 (ja) * | 2004-02-05 | 2010-07-21 | 味の素株式会社 | 変異型微生物およびこれを用いたペプチドの製造方法 |
EP1767628A4 (en) * | 2004-06-25 | 2008-08-27 | Kyowa Hakko Kogyo Kk | PROCESS FOR THE PREPARATION OF DIPEPTIDES OR DIPEPTIDE DERIVATIVES |
CN1320099C (zh) * | 2005-02-04 | 2007-06-06 | 南京工业大学 | 利用北里孢菌PL6-3制备ε-聚赖氨酸及其盐的方法 |
US8685914B2 (en) * | 2005-03-29 | 2014-04-01 | Kyowa Hakko Bio Co., Ltd. | L-alanyl-L-glutamine crystal |
US20090197303A1 (en) * | 2005-12-27 | 2009-08-06 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing dipeptides |
JP2007319063A (ja) * | 2006-05-31 | 2007-12-13 | Okayama Prefecture | ジペプチドの製造方法 |
US20090306340A1 (en) * | 2006-06-28 | 2009-12-10 | Kyowa Hakko Bio Co., Ltd. | Method for purification of oligopeptides |
WO2008086466A1 (en) * | 2007-01-11 | 2008-07-17 | Danisco Us Inc., Genencor Division | Enzyme production in culture medium comprising raw glycerol |
EP2143786B1 (en) | 2007-04-06 | 2014-12-10 | Kyowa Hakko Bio Co., Ltd. | Method for producing dipeptide |
US8104191B2 (en) | 2008-07-31 | 2012-01-31 | Electrolux Home Products, Inc. | Laundry dryer providing moisture application during tumbling and reduced airflow |
US8946164B2 (en) | 2010-04-07 | 2015-02-03 | Kyoto University | Bioactive peptide |
KR101144987B1 (ko) * | 2010-04-12 | 2012-05-11 | 목원대학교 산학협력단 | 크리세오박테리움 fbf-7 균주 배양물 및 이를 함유하는 뿌리혹선충 방제용 조성물 |
RU2012129311A (ru) | 2012-07-11 | 2014-01-20 | Закрытое акционерное общество " Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | Днк, кодирующая дипептид-синтезирующий фермер (варианты), бактерия рода escherichia и способ получения дипептидов с ее использованием |
CN103114068B (zh) * | 2013-03-15 | 2014-06-11 | 江苏南资环保科技有限公司 | 一株哌嗪降解无色杆菌菌mbpq-cg及其应用 |
RU2560980C2 (ru) * | 2013-07-11 | 2015-08-20 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") | ДНК, КОДИРУЮЩАЯ ДИПЕПТИД-СИНТЕЗИРУЮЩИЙ ФЕРМЕНТ (ВАРИАНТЫ), БАКТЕРИЯ РОДА Escherichia И СПОСОБ ПОЛУЧЕНИЯ ДИПЕПТИДОВ С ЕЕ ИСПОЛЬЗОВАНИЕМ |
CN104480172A (zh) * | 2014-11-19 | 2015-04-01 | 江南大学 | 一种利用重组大肠杆菌生产l-丙氨酰-l-谷氨酰胺的方法 |
WO2016140277A1 (ja) | 2015-03-02 | 2016-09-09 | 国立大学法人京都大学 | ペプチド |
CN106565822A (zh) * | 2016-10-17 | 2017-04-19 | 湖北泓肽生物科技有限公司 | 手性l‑丙氨酰‑苯丙氨酸的制备方法 |
KR102183558B1 (ko) * | 2016-12-30 | 2020-11-26 | 이노바이오 코오포레이션 리미티드 | L-알라닐-l-글루타민 생합성 효소를 코딩하는 유전자 및 그 용도 |
FR3076992B1 (fr) | 2018-01-23 | 2022-10-14 | Samirath Adeyendju Akanke Alli | Dispositif de protection vulvaire, kit de protection vulvaire et anale et procede d'installation d'une telle protection |
US20220073958A1 (en) * | 2018-12-18 | 2022-03-10 | Patheon Austria Gmbh & Co Kg | Single step biocatalytic amidation |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5392729A (en) | 1977-01-27 | 1978-08-15 | Toyo Soda Mfg Co Ltd | Adduct of dipeptide derivatives and amino acid derivatives and process for their preparation |
JPS5836387A (ja) | 1981-08-24 | 1983-03-03 | Seikagaku Kogyo Co Ltd | プロリンイミノペプチダ−ゼおよびその製造法 |
JPH0640832B2 (ja) | 1985-05-10 | 1994-06-01 | 味の素株式会社 | インタ−ロイキン2ポリペプチドの回収方法 |
DK72587D0 (da) | 1987-02-13 | 1987-02-13 | Carlsberg Biotechnology Ltd | Fremgangsmaade til enzymatisk fremstilling af dipeptider |
JPH0832717B2 (ja) | 1987-10-07 | 1996-03-29 | 味の素株式会社 | グルタミン誘導体の製造方法 |
JPH01215288A (ja) | 1988-02-25 | 1989-08-29 | Yakult Honsha Co Ltd | プロリンイミノペプチダーゼおよびその製造方法 |
DK163435C (da) | 1988-08-12 | 1992-07-20 | Carlsberg Biotechnology Ltd | Fremgangsmaade til enzymatisk fremstilling af dipeptider og derivater deraf |
JPH02113887A (ja) | 1988-10-21 | 1990-04-26 | Ajinomoto Co Inc | プロリンイミノペプチダーゼをコードする遺伝子を有する組換えdna及び該組換えdnaを有する細胞を用いるプロリンイミノペプチダーゼの製造法 |
JPH0313391A (ja) | 1989-06-13 | 1991-01-22 | Canon Inc | 感熱転写材 |
JP2897274B2 (ja) | 1989-08-30 | 1999-05-31 | 東ソー株式会社 | ジペプチド類の製造方法 |
JPH03133391A (ja) | 1989-10-17 | 1991-06-06 | Kyowa Hakko Kogyo Co Ltd | ジペプチドの製造法 |
JP2907479B2 (ja) | 1990-02-28 | 1999-06-21 | 輝彦 別府 | ニトリルヒドラターゼ活性を有するポリペプチドをコードする遺伝子dna、これを含有する形質転換体及びアミド類の製造法 |
KR930002966B1 (ko) | 1990-11-24 | 1993-04-16 | 주식회사 미 원 | 디펩티드의 제조방법 |
JPH0638769A (ja) | 1992-02-21 | 1994-02-15 | Q洋紡績株式会社 | プロリンイミノペプチダーゼの遺伝情報を有するdna断片およびその用途 |
JP3473976B2 (ja) | 1992-10-29 | 2003-12-08 | 協和醗酵工業株式会社 | アラニルグルタミンの製造法 |
JP2972903B2 (ja) | 1992-12-25 | 1999-11-08 | 農林水産省食品総合研究所長 | ジペプチドの製造法 |
JPH09503642A (ja) | 1993-05-18 | 1997-04-15 | ユニリーバー・ナームローゼ・ベンノートシャープ | プロリンイミノペプチダーゼ、その生産方法並びに食品組成物の風味付けに対する使用 |
JP3528205B2 (ja) * | 1993-07-30 | 2004-05-17 | 味の素株式会社 | L−3,4−ジヒドロキシフェニルアラニンの製造方法 |
JPH08231586A (ja) * | 1994-12-28 | 1996-09-10 | Ajinomoto Co Inc | α−L−アスパルチルジペプチドアミド誘導体の製造法 |
FR2728905A1 (fr) * | 1994-12-29 | 1996-07-05 | Rhone Poulenc Nutrition Animal | Nouvelle acide amine amidohydrolase, sequence nuclotidique correspondant et leurs utilisations |
JP3012493B2 (ja) | 1995-08-07 | 2000-02-21 | 農林水産省食品総合研究所長 | 成分分離方法 |
JPH09121860A (ja) | 1995-10-31 | 1997-05-13 | Rikagaku Kenkyusho | プロリンイミノペプチダーゼ |
JPH09248197A (ja) | 1996-03-12 | 1997-09-22 | Natl Food Res Inst | ジペプチドエステルの製造方法 |
US5837483A (en) | 1996-10-15 | 1998-11-17 | Holland Sweetener Company V.O.F. | Enzymatic method for producing N-formyl-α-L-aspartyl-L-phenylalanine methyl ester |
JPH10174597A (ja) | 1996-10-15 | 1998-06-30 | Tosoh Corp | N−ホルミル−α−L−アスパルチル−L−フェニルアラニンメチルエステルの酵素合成法 |
JPH10136992A (ja) | 1996-11-07 | 1998-05-26 | Ajinomoto Co Inc | α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造方法 |
US6380370B1 (en) * | 1997-08-14 | 2002-04-30 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics |
JP2000078971A (ja) * | 1998-09-04 | 2000-03-21 | Kanegafuchi Chem Ind Co Ltd | D−、l−アミノ酸エステルよりオリゴペプチドを合成する新規酵素およびこれを生産する微生物 |
EP2302058A1 (en) | 1999-06-25 | 2011-03-30 | Paik Kwang Industrial Co., Ltd. | Corynebacterium glutamicum genes encoding proteins involved in homeostasis and adaptation |
JP4623825B2 (ja) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
RU2279440C2 (ru) | 2001-07-26 | 2006-07-10 | Адзиномото Ко., Инк. | Способ получения l-аланил-l-глутамина |
US20050148048A1 (en) * | 2003-11-27 | 2005-07-07 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing dipeptides |
-
2002
- 2002-07-26 RU RU2003137001/13A patent/RU2279440C2/ru not_active IP Right Cessation
- 2002-07-26 CN CNB028189892A patent/CN1268742C/zh not_active Expired - Fee Related
- 2002-07-26 JP JP2003515546A patent/JP4289151B2/ja not_active Expired - Fee Related
- 2002-07-26 KR KR1020047001175A patent/KR100635803B1/ko not_active IP Right Cessation
- 2002-07-26 CN CNB028148452A patent/CN100422207C/zh not_active Expired - Fee Related
- 2002-07-26 DK DK08000584.6T patent/DK1911839T3/da active
- 2002-07-26 WO PCT/JP2002/007635 patent/WO2003010307A1/ja active IP Right Grant
- 2002-07-26 US US10/481,087 patent/US7037673B2/en not_active Expired - Fee Related
- 2002-07-26 KR KR1020037015497A patent/KR100602808B1/ko not_active IP Right Cessation
- 2002-07-26 RU RU2004105652/13A patent/RU2280077C2/ru not_active IP Right Cessation
- 2002-07-26 CN CNA02812670XA patent/CN1529712A/zh active Pending
- 2002-07-26 WO PCT/JP2002/007633 patent/WO2003010187A1/ja active Application Filing
- 2002-07-26 JP JP2003515658A patent/JP4239819B2/ja not_active Expired - Fee Related
- 2002-07-26 EP EP02751741A patent/EP1411116B1/en not_active Expired - Lifetime
- 2002-07-26 CN CN2008100924127A patent/CN101982546A/zh active Pending
- 2002-07-26 EP EP02751739A patent/EP1411060A4/en not_active Withdrawn
- 2002-07-26 US US10/476,885 patent/US7754466B2/en not_active Expired - Fee Related
- 2002-07-26 WO PCT/JP2002/007634 patent/WO2003010189A1/ja not_active Application Discontinuation
- 2002-07-26 DE DE60226243T patent/DE60226243T2/de not_active Expired - Lifetime
- 2002-07-26 JP JP2003515548A patent/JP4273967B2/ja not_active Expired - Lifetime
- 2002-07-26 EP EP08000584A patent/EP1911839B1/en not_active Expired - Lifetime
- 2002-07-26 EP EP02751740A patent/EP1411062A4/en not_active Withdrawn
- 2002-07-26 DK DK02751741T patent/DK1411116T3/da active
-
2004
- 2004-01-26 US US10/763,249 patent/US7288388B2/en not_active Expired - Fee Related
-
2005
- 2005-10-14 US US11/249,429 patent/US20070042459A1/en not_active Abandoned
- 2005-12-12 RU RU2005138717/13A patent/RU2316596C2/ru not_active IP Right Cessation
-
2006
- 2006-10-31 US US11/589,842 patent/US7618796B2/en not_active Expired - Fee Related
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