DK1326862T3 - Krystallinsk monohydrat af tiotropiumbromid, fremgangsmåde til fremstilling deraf og anvendelse deraf til fremstilling af et lægemiddel - Google Patents

Krystallinsk monohydrat af tiotropiumbromid, fremgangsmåde til fremstilling deraf og anvendelse deraf til fremstilling af et lægemiddel

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Publication number
DK1326862T3
DK1326862T3 DK01983510T DK01983510T DK1326862T3 DK 1326862 T3 DK1326862 T3 DK 1326862T3 DK 01983510 T DK01983510 T DK 01983510T DK 01983510 T DK01983510 T DK 01983510T DK 1326862 T3 DK1326862 T3 DK 1326862T3
Authority
DK
Denmark
Prior art keywords
drug
manufacture
preparation
tiotropium bromide
crystalline monohydrate
Prior art date
Application number
DK01983510T
Other languages
Danish (da)
English (en)
Inventor
Michael Trunk
Rolf Banholzer
Peter Sieger
Peter Specht
Andreas Mathes
Christian Kulinna
Manfred Ludwig August Graulich
Helmut Meissner
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1326862(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Application granted granted Critical
Publication of DK1326862T3 publication Critical patent/DK1326862T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK01983510T 2000-10-12 2001-09-28 Krystallinsk monohydrat af tiotropiumbromid, fremgangsmåde til fremstilling deraf og anvendelse deraf til fremstilling af et lægemiddel DK1326862T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10050621 2000-10-12
PCT/EP2001/011225 WO2002030928A1 (de) 2000-10-12 2001-09-28 Kristallines monohydrat, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels

Publications (1)

Publication Number Publication Date
DK1326862T3 true DK1326862T3 (da) 2004-11-22

Family

ID=7659568

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01983510T DK1326862T3 (da) 2000-10-12 2001-09-28 Krystallinsk monohydrat af tiotropiumbromid, fremgangsmåde til fremstilling deraf og anvendelse deraf til fremstilling af et lægemiddel

Country Status (47)

Country Link
EP (2) EP1468998A1 (sr)
JP (1) JP3764422B2 (sr)
KR (1) KR100823860B1 (sr)
CN (2) CN1221549C (sr)
AP (1) AP1572A (sr)
AR (2) AR034389A1 (sr)
AT (1) ATE276253T1 (sr)
AU (2) AU1499602A (sr)
BG (1) BG66161B1 (sr)
BR (1) BR0114584A (sr)
CA (1) CA2425539C (sr)
CR (1) CR6938A (sr)
CZ (1) CZ301841B6 (sr)
DE (1) DE50103666D1 (sr)
DK (1) DK1326862T3 (sr)
DZ (1) DZ3478A1 (sr)
EA (1) EA004381B1 (sr)
EC (1) ECSP034540A (sr)
EE (1) EE04567B1 (sr)
EG (1) EG24142A (sr)
ES (1) ES2228965T3 (sr)
GE (1) GEP20063905B (sr)
HK (2) HK1060567A1 (sr)
HR (1) HRP20030276B1 (sr)
HU (1) HU226830B1 (sr)
IL (2) IL155335A0 (sr)
IS (1) IS2339B (sr)
MA (1) MA25842A1 (sr)
ME (2) ME00243B (sr)
MX (1) MXPA03003221A (sr)
MY (1) MY126931A (sr)
NO (1) NO328465B1 (sr)
NZ (1) NZ525733A (sr)
OA (1) OA12403A (sr)
PE (1) PE20020422A1 (sr)
PL (1) PL207870B1 (sr)
PT (1) PT1326862E (sr)
RS (1) RS50218B (sr)
SA (1) SA01220412B1 (sr)
SI (1) SI1326862T1 (sr)
SK (1) SK287009B6 (sr)
TR (1) TR200402579T4 (sr)
TW (1) TW589313B (sr)
UA (1) UA74215C2 (sr)
UY (2) UY26962A1 (sr)
WO (1) WO2002030928A1 (sr)
ZA (1) ZA200302500B (sr)

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EA200300457A1 (ru) 2003-10-30
HUP0301022A2 (hu) 2003-10-28
CR6938A (es) 2004-10-28
AU2002214996B2 (en) 2007-03-15
ES2228965T3 (es) 2005-04-16
ATE276253T1 (de) 2004-10-15
GEP20063905B (en) 2006-08-25
IL155335A0 (en) 2003-11-23
EG24142A (en) 2008-08-06
ZA200302500B (en) 2004-04-22
CN1221549C (zh) 2005-10-05
EE200300171A (et) 2003-06-16
DE50103666D1 (de) 2004-10-21
PT1326862E (pt) 2004-11-30
CA2425539C (en) 2007-04-03
AP2003002775A0 (en) 2003-03-31
NO20031694L (no) 2003-04-11
YU27303A (sh) 2006-05-25
MEP40008A (en) 2011-02-10
EP1468998A1 (de) 2004-10-20
HUP0301022A3 (en) 2005-12-28
CN1733761A (zh) 2006-02-15
NO328465B1 (no) 2010-02-22
CN100519558C (zh) 2009-07-29
PE20020422A1 (es) 2002-06-28
BG66161B1 (bg) 2011-09-30
KR100823860B1 (ko) 2008-04-21
EA004381B1 (ru) 2004-04-29
MA25842A1 (fr) 2003-07-01
EP1326862B1 (de) 2004-09-15
CN1469877A (zh) 2004-01-21
PL207870B1 (pl) 2011-02-28
AR034389A1 (es) 2004-02-25
HK1086557A1 (en) 2006-09-22
SK287009B6 (sk) 2009-09-07
KR20030042008A (ko) 2003-05-27
EP1326862A1 (de) 2003-07-16
CA2425539A1 (en) 2003-04-11
UY26962A1 (es) 2002-06-20
HRP20030276B1 (en) 2006-02-28
ECSP034540A (es) 2003-07-25
UA74215C2 (uk) 2005-11-15
IS6772A (is) 2003-04-09
UY34901A (es) 2015-02-27
HK1060567A1 (en) 2004-08-13
IL155335A (en) 2009-02-11
BG107687A (bg) 2003-09-30
AR068527A2 (es) 2009-11-18
WO2002030928A1 (de) 2002-04-18
CZ301841B6 (cs) 2010-07-07
MXPA03003221A (es) 2004-12-03
HU226830B1 (en) 2009-11-30
JP3764422B2 (ja) 2006-04-05
HRP20030276A2 (en) 2005-02-28
DZ3478A1 (fr) 2002-04-18
PL366041A1 (en) 2005-01-24
JP2004526668A (ja) 2004-09-02
IS2339B (is) 2008-02-15
NO20031694D0 (no) 2003-04-11
AU1499602A (en) 2002-04-22
AP1572A (en) 2006-02-13
ME00243B (me) 2011-05-10
TW589313B (en) 2004-06-01
RS50218B (sr) 2009-07-15
OA12403A (en) 2006-04-18
MY126931A (en) 2006-10-31
SK4362003A3 (en) 2003-08-05
SA01220412B1 (ar) 2006-11-05
NZ525733A (en) 2005-01-28
BR0114584A (pt) 2003-08-26
TR200402579T4 (tr) 2004-12-21
EE04567B1 (et) 2005-12-15
SI1326862T1 (en) 2005-02-28

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