DK1381605T3 - Mercaptoacetylamidderivater, en fremgangsmåde til deres fremstilling og deres anvendelse - Google Patents

Mercaptoacetylamidderivater, en fremgangsmåde til deres fremstilling og deres anvendelse

Info

Publication number
DK1381605T3
DK1381605T3 DK02732549T DK02732549T DK1381605T3 DK 1381605 T3 DK1381605 T3 DK 1381605T3 DK 02732549 T DK02732549 T DK 02732549T DK 02732549 T DK02732549 T DK 02732549T DK 1381605 T3 DK1381605 T3 DK 1381605T3
Authority
DK
Denmark
Prior art keywords
preparation
mercaptoacetylamide derivatives
mercaptoacetylamide
derivatives
Prior art date
Application number
DK02732549T
Other languages
English (en)
Inventor
Shujaath Mehdi
Jack Roger Koehl
Barbara Ann Anderson
Manfred Gerken
Bernd Jablonka
Werner Seiz
Bernhard Seuring
Gary A Flynn
Heinz-Werner Kleemann
Wolfgang Linz
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Priority claimed from PCT/EP2002/003668 external-priority patent/WO2002083671A1/en
Application granted granted Critical
Publication of DK1381605T3 publication Critical patent/DK1381605T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DK02732549T 2001-04-12 2002-04-03 Mercaptoacetylamidderivater, en fremgangsmåde til deres fremstilling og deres anvendelse DK1381605T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28330501P 2001-04-12 2001-04-12
GBGB0119305.1A GB0119305D0 (en) 2001-04-12 2001-08-08 Mercaptoacetylamide derivatives,a process for their preparation and their use
PCT/EP2002/003668 WO2002083671A1 (en) 2001-04-12 2002-04-03 Mercaptoacetylamide derivatives, a process for their preparation and their use
EP02732549A EP1381605B1 (en) 2001-04-12 2002-04-03 Mercaptoacetylamide derivatives, a process for their preparation and their use

Publications (1)

Publication Number Publication Date
DK1381605T3 true DK1381605T3 (da) 2005-05-09

Family

ID=23085405

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02732549T DK1381605T3 (da) 2001-04-12 2002-04-03 Mercaptoacetylamidderivater, en fremgangsmåde til deres fremstilling og deres anvendelse

Country Status (17)

Country Link
US (1) US6602866B2 (da)
KR (1) KR100910929B1 (da)
AR (1) AR034307A1 (da)
CR (1) CR7074A (da)
DK (1) DK1381605T3 (da)
EC (1) ECSP034782A (da)
GB (1) GB0119305D0 (da)
GT (1) GT200200069A (da)
IL (1) IL158289A (da)
MY (1) MY128226A (da)
PE (1) PE20021079A1 (da)
RS (1) RS50919B (da)
TN (1) TNSN03083A1 (da)
TW (1) TWI319764B (da)
UA (1) UA75647C2 (da)
UY (1) UY27255A1 (da)
ZA (1) ZA200307096B (da)

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NZ723772A (en) 2012-06-08 2017-06-30 Theravance Biopharma R&D Ip Llc Neprilysin inhibitors
CN104470521B (zh) 2012-06-08 2017-04-12 施万生物制药研发Ip有限责任公司 脑啡肽酶抑制剂
EP2882716B9 (en) 2012-08-08 2018-12-26 Theravance Biopharma R&D IP, LLC Neprilysin inhibitors
SI2964616T1 (sl) 2013-03-05 2017-08-31 Theravance Biopharma R&D Ip, Llc Zaviralci neprilizina
RU2016135057A (ru) 2014-01-30 2018-03-12 ТЕРЕВАНС БАЙОФАРМА Ар энд Ди АйПи, ЭлЭлСи Производные 5-бифенил-4-гетероарилкарбониламинопентановой кислоты в качестве ингибиторов неприлизина
US9593110B2 (en) 2014-01-30 2017-03-14 Theravence Biopharma R&D IP, LLC Neprilysin inhibitors
CN107257785B (zh) 2015-02-11 2020-07-07 施万生物制药研发Ip有限责任公司 作为脑啡肽酶抑制剂的(2s,4r)-5-(5’-氯-2’-氟联苯-4-基)-4-(乙氧基草酰基氨基)-2-羟甲基-2-甲基戊酸
EP3259255B1 (en) 2015-02-19 2020-10-21 Theravance Biopharma R&D IP, LLC (2r,4r)-5-(5'-chloro-2'-fluorobiphenyl-4-yl)-2-hydroxy-4-[(5-methyloxazole-2-carbonyl)amino]pentanoic acid
CN108779084A (zh) 2016-03-08 2018-11-09 施万生物制药研发Ip有限责任公司 结晶型(2s,4r)-5-(5′-氯-2′-氟-[1,1′-联苯]-4-基)-2-(乙氧基甲基)-4-(3-羟基异恶唑-5-甲酰氨基)-2-甲基戊酸和其用途

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Also Published As

Publication number Publication date
MY128226A (en) 2007-01-31
UY27255A1 (es) 2002-07-31
ECSP034782A (es) 2003-12-01
GT200200069A (es) 2002-12-17
KR20040008153A (ko) 2004-01-28
RS50919B (sr) 2010-08-31
US6602866B2 (en) 2003-08-05
UA75647C2 (en) 2006-05-15
TWI319764B (en) 2010-01-21
PE20021079A1 (es) 2003-02-19
ZA200307096B (en) 2004-09-06
CR7074A (es) 2007-12-04
US20020193589A1 (en) 2002-12-19
IL158289A (en) 2010-11-30
KR100910929B1 (ko) 2009-08-06
GB0119305D0 (en) 2001-10-03
TNSN03083A1 (en) 2005-12-23
AR034307A1 (es) 2004-02-18
YU78703A (sh) 2006-05-25

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