DK1261603T3 - Flavonderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel - Google Patents

Flavonderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel

Info

Publication number
DK1261603T3
DK1261603T3 DK01909906T DK01909906T DK1261603T3 DK 1261603 T3 DK1261603 T3 DK 1261603T3 DK 01909906 T DK01909906 T DK 01909906T DK 01909906 T DK01909906 T DK 01909906T DK 1261603 T3 DK1261603 T3 DK 1261603T3
Authority
DK
Denmark
Prior art keywords
drug
processes
preparation
flavone derivatives
flavone
Prior art date
Application number
DK01909906T
Other languages
English (en)
Other versions
DK1261603T5 (da
Inventor
Jean-Luc Haesslein
Jidong Zhang
Dominique Lefrancois
Eric Uridat
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of DK1261603T3 publication Critical patent/DK1261603T3/da
Application granted granted Critical
Publication of DK1261603T5 publication Critical patent/DK1261603T5/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK01909906T 2000-02-29 2001-02-27 Flavonderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel DK1261603T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0002528A FR2805538B1 (fr) 2000-02-29 2000-02-29 Nouveaux derives de flavones, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
PCT/FR2001/000561 WO2001064673A1 (fr) 2000-02-29 2001-02-27 Derives de flavones, leur procede de preparation, leur application a titre de medicaments

Publications (2)

Publication Number Publication Date
DK1261603T3 true DK1261603T3 (da) 2006-12-27
DK1261603T5 DK1261603T5 (da) 2007-07-09

Family

ID=8847520

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01909906T DK1261603T5 (da) 2000-02-29 2001-02-27 Flavonderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemiddel

Country Status (16)

Country Link
US (1) US20030119816A1 (da)
EP (1) EP1261603B1 (da)
JP (1) JP5118282B2 (da)
AR (1) AR029479A1 (da)
AT (1) ATE336490T1 (da)
AU (1) AU783663B2 (da)
CA (1) CA2403424C (da)
CY (1) CY1105786T1 (da)
DE (1) DE60122295T2 (da)
DK (1) DK1261603T5 (da)
ES (1) ES2270984T3 (da)
FR (1) FR2805538B1 (da)
MY (1) MY159418A (da)
PT (1) PT1261603E (da)
TW (1) TWI282338B (da)
WO (1) WO2001064673A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2493871T3 (da) * 2009-10-30 2014-11-10 Prestwick Chemical Sas Nye oximderivater samt deres anvendelse som allosteriske modulatorer af metabotropiske glutamatreceptorer
CN103896895A (zh) * 2013-12-31 2014-07-02 浙江工业大学 一种香豆素衍生物的制备方法
WO2018094275A1 (en) * 2016-11-18 2018-05-24 Tolero Pharmaceuticals, Inc. Alvocidib prodrugs and their use as protein kinase inhibitors
US11497756B2 (en) 2017-09-12 2022-11-15 Sumitomo Pharma Oncology, Inc. Treatment regimen for cancers that are insensitive to BCL-2 inhibitors using the MCL-1 inhibitor alvocidib
CN113490499A (zh) 2018-12-04 2021-10-08 大日本住友制药肿瘤公司 用作治疗癌症的活性剂的cdk9抑制剂及其多晶型物
US11793802B2 (en) 2019-03-20 2023-10-24 Sumitomo Pharma Oncology, Inc. Treatment of acute myeloid leukemia (AML) with venetoclax failure
CN111057035B (zh) * 2019-11-05 2021-10-26 中国人民解放军第二军医大学 一种黄芩素衍生物及其制备方法与应用
GB202104122D0 (en) * 2021-03-24 2021-05-05 Floratek Pharma Ag Compounds and their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN164232B (da) * 1986-04-11 1989-02-04 Hoechst India
DE3836676A1 (de) * 1988-10-28 1990-05-03 Hoechst Ag Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
US5733920A (en) * 1995-10-31 1998-03-31 Mitotix, Inc. Inhibitors of cyclin dependent kinases
US5908934A (en) * 1996-09-26 1999-06-01 Bristol-Myers Squibb Company Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

Also Published As

Publication number Publication date
JP5118282B2 (ja) 2013-01-16
ATE336490T1 (de) 2006-09-15
ES2270984T3 (es) 2007-04-16
MY159418A (en) 2017-01-13
FR2805538A1 (fr) 2001-08-31
EP1261603A1 (fr) 2002-12-04
DE60122295D1 (de) 2006-09-28
US20030119816A1 (en) 2003-06-26
CA2403424C (fr) 2011-02-01
TWI282338B (en) 2007-06-11
AR029479A1 (es) 2003-07-02
PT1261603E (pt) 2007-01-31
DE60122295T2 (de) 2007-11-15
EP1261603B1 (fr) 2006-08-16
CY1105786T1 (el) 2011-02-02
WO2001064673A1 (fr) 2001-09-07
JP2003525290A (ja) 2003-08-26
AU3750101A (en) 2001-09-12
AU783663B2 (en) 2005-11-24
FR2805538B1 (fr) 2006-08-04
DK1261603T5 (da) 2007-07-09
CA2403424A1 (fr) 2001-09-07

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