MEP40008A - Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament - Google Patents

Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Info

Publication number
MEP40008A
MEP40008A MEP-400/08A MEP40008A MEP40008A ME P40008 A MEP40008 A ME P40008A ME P40008 A MEP40008 A ME P40008A ME P40008 A MEP40008 A ME P40008A
Authority
ME
Montenegro
Prior art keywords
medicament
producing
production
same
crystalline monohydrate
Prior art date
Application number
MEP-400/08A
Other languages
Bosnian (bs)
Inventor
Rolf Banholzer
Peter Sieger
Christian Kulinna
Michael Trunk
Manfred Ludwig August Graulich
Peter Specht
Helmut Meissner
Andreas Mathes
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MEP40008(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MEP40008A publication Critical patent/MEP40008A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Pronalazak se odnosi na kristalni monohidrat (1α,2ß,4β,5α,7β)-7-[(hidroksi-2-tienilacetil)oksi]-9,9-dimetil-3-oksa-9-azoniatriciklo-[3.3.1.02,4]nonan-bromida, na postupak za njegovo pripremanje, kao i na njegovu primjenu za pripremanje lijekq, naročito za pripremanje lijeka sa antiholinergijskim dejstvom.The invention relates to crystalline monohydrate (1α, 2ß, 4β, 5α, 7β) -7 - [(hydroxy-2-thienylacetyl) oxy] -9,9-dimethyl-3-oxa-9-azoniatricyclo- [3.3.1.02, 4] nonan bromide, to a process for its preparation as well as to its use for the preparation of medicaments, in particular for the preparation of a medicament with anticholinergic action.

MEP-400/08A 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament MEP40008A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10050621 2000-10-12
YU27303A RS50218B (en) 2000-10-12 2001-09-28 Crystalline monohydrate,method for producing the same and the use thereof in the production of a medicament
PCT/EP2001/011225 WO2002030928A1 (en) 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Publications (1)

Publication Number Publication Date
MEP40008A true MEP40008A (en) 2011-02-10

Family

ID=7659568

Family Applications (2)

Application Number Title Priority Date Filing Date
MEP-400/08A MEP40008A (en) 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament
MEP-2008-400A ME00243B (en) 2000-10-12 2001-09-28 Crystalline monohydrate of tiotropiumbromide, method for producing the same and the use thereof in the production of a medicament

Family Applications After (1)

Application Number Title Priority Date Filing Date
MEP-2008-400A ME00243B (en) 2000-10-12 2001-09-28 Crystalline monohydrate of tiotropiumbromide, method for producing the same and the use thereof in the production of a medicament

Country Status (47)

Country Link
EP (2) EP1326862B1 (en)
JP (1) JP3764422B2 (en)
KR (1) KR100823860B1 (en)
CN (2) CN1221549C (en)
AP (1) AP1572A (en)
AR (2) AR034389A1 (en)
AT (1) ATE276253T1 (en)
AU (2) AU1499602A (en)
BG (1) BG66161B1 (en)
BR (1) BR0114584A (en)
CA (1) CA2425539C (en)
CR (1) CR6938A (en)
CZ (1) CZ301841B6 (en)
DE (1) DE50103666D1 (en)
DK (1) DK1326862T3 (en)
DZ (1) DZ3478A1 (en)
EA (1) EA004381B1 (en)
EC (1) ECSP034540A (en)
EE (1) EE04567B1 (en)
EG (1) EG24142A (en)
ES (1) ES2228965T3 (en)
GE (1) GEP20063905B (en)
HK (2) HK1060567A1 (en)
HR (1) HRP20030276B1 (en)
HU (1) HU226830B1 (en)
IL (2) IL155335A0 (en)
IS (1) IS2339B (en)
MA (1) MA25842A1 (en)
ME (2) MEP40008A (en)
MX (1) MXPA03003221A (en)
MY (1) MY126931A (en)
NO (1) NO328465B1 (en)
NZ (1) NZ525733A (en)
OA (1) OA12403A (en)
PE (1) PE20020422A1 (en)
PL (1) PL207870B1 (en)
PT (1) PT1326862E (en)
RS (1) RS50218B (en)
SA (1) SA01220412B1 (en)
SI (1) SI1326862T1 (en)
SK (1) SK287009B6 (en)
TR (1) TR200402579T4 (en)
TW (1) TW589313B (en)
UA (1) UA74215C2 (en)
UY (2) UY26962A1 (en)
WO (1) WO2002030928A1 (en)
ZA (1) ZA200302500B (en)

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JP3764422B2 (en) 2006-04-05
CA2425539C (en) 2007-04-03
IS2339B (en) 2008-02-15
NO328465B1 (en) 2010-02-22
TW589313B (en) 2004-06-01
AP1572A (en) 2006-02-13
MA25842A1 (en) 2003-07-01
PL366041A1 (en) 2005-01-24
HU226830B1 (en) 2009-11-30
DK1326862T3 (en) 2004-11-22
IL155335A (en) 2009-02-11
NO20031694L (en) 2003-04-11
CZ301841B6 (en) 2010-07-07
UA74215C2 (en) 2005-11-15
IL155335A0 (en) 2003-11-23
AU1499602A (en) 2002-04-22
HUP0301022A2 (en) 2003-10-28
UY26962A1 (en) 2002-06-20
CN1733761A (en) 2006-02-15
CN100519558C (en) 2009-07-29
BR0114584A (en) 2003-08-26
NZ525733A (en) 2005-01-28
OA12403A (en) 2006-04-18
CA2425539A1 (en) 2003-04-11
DZ3478A1 (en) 2002-04-18
BG107687A (en) 2003-09-30
DE50103666D1 (en) 2004-10-21
CN1221549C (en) 2005-10-05
EE200300171A (en) 2003-06-16
GEP20063905B (en) 2006-08-25
PE20020422A1 (en) 2002-06-28
AU2002214996B2 (en) 2007-03-15
ECSP034540A (en) 2003-07-25
YU27303A (en) 2006-05-25
PT1326862E (en) 2004-11-30
MY126931A (en) 2006-10-31
AP2003002775A0 (en) 2003-03-31
IS6772A (en) 2003-04-09
EA200300457A1 (en) 2003-10-30
MXPA03003221A (en) 2004-12-03
KR20030042008A (en) 2003-05-27
RS50218B (en) 2009-07-15
HUP0301022A3 (en) 2005-12-28
HRP20030276B1 (en) 2006-02-28
ME00243B (en) 2011-05-10
SA01220412B1 (en) 2006-11-05
PL207870B1 (en) 2011-02-28
CR6938A (en) 2004-10-28
CN1469877A (en) 2004-01-21
BG66161B1 (en) 2011-09-30
AR068527A2 (en) 2009-11-18
EG24142A (en) 2008-08-06
HRP20030276A2 (en) 2005-02-28
HK1060567A1 (en) 2004-08-13
AR034389A1 (en) 2004-02-25
WO2002030928A1 (en) 2002-04-18
SK287009B6 (en) 2009-09-07
ZA200302500B (en) 2004-04-22
EE04567B1 (en) 2005-12-15
SI1326862T1 (en) 2005-02-28
SK4362003A3 (en) 2003-08-05
UY34901A (en) 2015-02-27
ES2228965T3 (en) 2005-04-16
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TR200402579T4 (en) 2004-12-21
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JP2004526668A (en) 2004-09-02
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