GEP20063905B - Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament - Google Patents

Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Info

Publication number
GEP20063905B
GEP20063905B GE5214A GEAP2001005214A GEP20063905B GE P20063905 B GEP20063905 B GE P20063905B GE 5214 A GE5214 A GE 5214A GE AP2001005214 A GEAP2001005214 A GE AP2001005214A GE P20063905 B GEP20063905 B GE P20063905B
Authority
GE
Georgia
Prior art keywords
producing
production
same
medicament
crystalline monohydrate
Prior art date
Application number
GE5214A
Inventor
Rolf Banholzer
Peter Sieger
Christian Kulinna
Michael Trunk
Manfred Ludwig August Graulich
Peter Specht
Helmut Meissner
Andreas Mathes
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GEP20063905(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of GEP20063905B publication Critical patent/GEP20063905B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to a crystalline mono¬hydrate of thiotropium-bromide, to a method for producing the same, inhalation powder on its base. The use of crystalline monohydrate of thi¬otro¬pium-bromide in the production of a medi¬cament, especially for producing a medi¬cament that has an anticholinergic effect.
GE5214A 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament GEP20063905B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10050621 2000-10-12

Publications (1)

Publication Number Publication Date
GEP20063905B true GEP20063905B (en) 2006-08-25

Family

ID=7659568

Family Applications (1)

Application Number Title Priority Date Filing Date
GE5214A GEP20063905B (en) 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Country Status (47)

Country Link
EP (2) EP1468998A1 (en)
JP (1) JP3764422B2 (en)
KR (1) KR100823860B1 (en)
CN (2) CN1221549C (en)
AP (1) AP1572A (en)
AR (2) AR034389A1 (en)
AT (1) ATE276253T1 (en)
AU (2) AU1499602A (en)
BG (1) BG66161B1 (en)
BR (1) BR0114584A (en)
CA (1) CA2425539C (en)
CR (1) CR6938A (en)
CZ (1) CZ301841B6 (en)
DE (1) DE50103666D1 (en)
DK (1) DK1326862T3 (en)
DZ (1) DZ3478A1 (en)
EA (1) EA004381B1 (en)
EC (1) ECSP034540A (en)
EE (1) EE04567B1 (en)
EG (1) EG24142A (en)
ES (1) ES2228965T3 (en)
GE (1) GEP20063905B (en)
HK (2) HK1060567A1 (en)
HR (1) HRP20030276B1 (en)
HU (1) HU226830B1 (en)
IL (2) IL155335A0 (en)
IS (1) IS2339B (en)
MA (1) MA25842A1 (en)
ME (2) MEP40008A (en)
MX (1) MXPA03003221A (en)
MY (1) MY126931A (en)
NO (1) NO328465B1 (en)
NZ (1) NZ525733A (en)
OA (1) OA12403A (en)
PE (1) PE20020422A1 (en)
PL (1) PL207870B1 (en)
PT (1) PT1326862E (en)
RS (1) RS50218B (en)
SA (1) SA01220412B1 (en)
SI (1) SI1326862T1 (en)
SK (1) SK287009B6 (en)
TR (1) TR200402579T4 (en)
TW (1) TW589313B (en)
UA (1) UA74215C2 (en)
UY (2) UY26962A1 (en)
WO (1) WO2002030928A1 (en)
ZA (1) ZA200302500B (en)

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ES2322148T3 (en) 2004-08-11 2009-06-17 BOEHRINGER INGELHEIM PHARMA GMBH &amp; CO. KG MEDICINES CONTAINING ANTI-POLINERGIC FOR TREATMENT IN URINARY ROADS.
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TR200402579T4 (en) 2004-12-21
BG107687A (en) 2003-09-30
PE20020422A1 (en) 2002-06-28
EP1468998A1 (en) 2004-10-20
SA01220412B1 (en) 2006-11-05
NO328465B1 (en) 2010-02-22
EP1326862A1 (en) 2003-07-16
MEP40008A (en) 2011-02-10
SK287009B6 (en) 2009-09-07
MY126931A (en) 2006-10-31
ES2228965T3 (en) 2005-04-16
CN1469877A (en) 2004-01-21
HRP20030276B1 (en) 2006-02-28
KR20030042008A (en) 2003-05-27
AR034389A1 (en) 2004-02-25
MA25842A1 (en) 2003-07-01
NZ525733A (en) 2005-01-28
AU2002214996B2 (en) 2007-03-15
IL155335A0 (en) 2003-11-23
NO20031694D0 (en) 2003-04-11
UY26962A1 (en) 2002-06-20
YU27303A (en) 2006-05-25
TW589313B (en) 2004-06-01
CZ301841B6 (en) 2010-07-07
HRP20030276A2 (en) 2005-02-28
MXPA03003221A (en) 2004-12-03
ECSP034540A (en) 2003-07-25
JP3764422B2 (en) 2006-04-05
UY34901A (en) 2015-02-27
IL155335A (en) 2009-02-11
SI1326862T1 (en) 2005-02-28
WO2002030928A1 (en) 2002-04-18
AP2003002775A0 (en) 2003-03-31
CA2425539C (en) 2007-04-03
EA200300457A1 (en) 2003-10-30
NO20031694L (en) 2003-04-11
CN1733761A (en) 2006-02-15
CA2425539A1 (en) 2003-04-11
EG24142A (en) 2008-08-06
CR6938A (en) 2004-10-28
PT1326862E (en) 2004-11-30
DZ3478A1 (en) 2002-04-18
HU226830B1 (en) 2009-11-30
BG66161B1 (en) 2011-09-30
IS2339B (en) 2008-02-15
AR068527A2 (en) 2009-11-18
AP1572A (en) 2006-02-13
OA12403A (en) 2006-04-18
HUP0301022A3 (en) 2005-12-28
IS6772A (en) 2003-04-09
HK1060567A1 (en) 2004-08-13
AU1499602A (en) 2002-04-22
RS50218B (en) 2009-07-15
SK4362003A3 (en) 2003-08-05
ME00243B (en) 2011-05-10
CN100519558C (en) 2009-07-29
KR100823860B1 (en) 2008-04-21
CN1221549C (en) 2005-10-05
EE200300171A (en) 2003-06-16
PL207870B1 (en) 2011-02-28
ATE276253T1 (en) 2004-10-15
HK1086557A1 (en) 2006-09-22
BR0114584A (en) 2003-08-26
DE50103666D1 (en) 2004-10-21
ZA200302500B (en) 2004-04-22
EP1326862B1 (en) 2004-09-15
JP2004526668A (en) 2004-09-02
HUP0301022A2 (en) 2003-10-28
UA74215C2 (en) 2005-11-15
DK1326862T3 (en) 2004-11-22
EA004381B1 (en) 2004-04-29
PL366041A1 (en) 2005-01-24
EE04567B1 (en) 2005-12-15

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