IL155335A0 - Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament - Google Patents

Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Info

Publication number
IL155335A0
IL155335A0 IL15533501A IL15533501A IL155335A0 IL 155335 A0 IL155335 A0 IL 155335A0 IL 15533501 A IL15533501 A IL 15533501A IL 15533501 A IL15533501 A IL 15533501A IL 155335 A0 IL155335 A0 IL 155335A0
Authority
IL
Israel
Prior art keywords
medicament
producing
production
same
crystalline monohydrate
Prior art date
Application number
IL15533501A
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7659568&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL155335(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL155335A0 publication Critical patent/IL155335A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
IL15533501A 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament IL155335A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10050621 2000-10-12
PCT/EP2001/011225 WO2002030928A1 (en) 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament

Publications (1)

Publication Number Publication Date
IL155335A0 true IL155335A0 (en) 2003-11-23

Family

ID=7659568

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15533501A IL155335A0 (en) 2000-10-12 2001-09-28 Crystalline monohydrate, method for producing the same and the use thereof in the production of a medicament
IL155335A IL155335A (en) 2000-10-12 2003-04-10 Crystalline monohydrate of tiotropium bromide, method for producing the same and the use thereof in the production of a medicament

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL155335A IL155335A (en) 2000-10-12 2003-04-10 Crystalline monohydrate of tiotropium bromide, method for producing the same and the use thereof in the production of a medicament

Country Status (47)

Country Link
EP (2) EP1326862B1 (en)
JP (1) JP3764422B2 (en)
KR (1) KR100823860B1 (en)
CN (2) CN1221549C (en)
AP (1) AP1572A (en)
AR (2) AR034389A1 (en)
AT (1) ATE276253T1 (en)
AU (2) AU2002214996B2 (en)
BG (1) BG66161B1 (en)
BR (1) BR0114584A (en)
CA (1) CA2425539C (en)
CR (1) CR6938A (en)
CZ (1) CZ301841B6 (en)
DE (1) DE50103666D1 (en)
DK (1) DK1326862T3 (en)
DZ (1) DZ3478A1 (en)
EA (1) EA004381B1 (en)
EC (1) ECSP034540A (en)
EE (1) EE04567B1 (en)
EG (1) EG24142A (en)
ES (1) ES2228965T3 (en)
GE (1) GEP20063905B (en)
HK (2) HK1060567A1 (en)
HR (1) HRP20030276B1 (en)
HU (1) HU226830B1 (en)
IL (2) IL155335A0 (en)
IS (1) IS2339B (en)
MA (1) MA25842A1 (en)
ME (2) ME00243B (en)
MX (1) MXPA03003221A (en)
MY (1) MY126931A (en)
NO (1) NO328465B1 (en)
NZ (1) NZ525733A (en)
OA (1) OA12403A (en)
PE (1) PE20020422A1 (en)
PL (1) PL207870B1 (en)
PT (1) PT1326862E (en)
RS (1) RS50218B (en)
SA (1) SA01220412B1 (en)
SI (1) SI1326862T1 (en)
SK (1) SK287009B6 (en)
TR (1) TR200402579T4 (en)
TW (1) TW589313B (en)
UA (1) UA74215C2 (en)
UY (2) UY26962A1 (en)
WO (1) WO2002030928A1 (en)
ZA (1) ZA200302500B (en)

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US7244415B2 (en) 2002-03-28 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations of an anhydrate
US7311894B2 (en) 2002-03-28 2007-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations containing an anticholinergic
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US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
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JP5165244B2 (en) 2003-11-03 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Method for producing tiotropium salt, tiotropium salt and pharmaceutical composition containing the same
RS20060291A (en) * 2003-11-03 2008-06-05 Boehringer Ingelheim International Gmbh., Novel crystalline anhydride with anticholinergic effect
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ATE427108T1 (en) 2004-08-11 2009-04-15 Boehringer Ingelheim Pharma MEDICINAL PRODUCTS CONTAINING ANTICHOLINERGICS FOR THE TREATMENT OF DISEASES OF THE URINARY TRACT
US20060079544A1 (en) * 2004-08-13 2006-04-13 Boehringer Ingelheim International Gmbh Medicaments for the prevention or treatment of alveolar pneumonia comprising an anticholinergic
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AU2006243238B2 (en) 2005-05-02 2012-05-24 Boehringer Ingelheim International Gmbh Novel crystalline forms of tiotropium bromide
CN101203513A (en) * 2005-05-02 2008-06-18 贝林格尔·英格海姆国际有限公司 Novel crystalline forms of tiotropium bromide
CA2611902C (en) * 2005-06-15 2013-08-27 Boehringer Ingelheim International Gmbh Tiotropium salts, compositions thereof, and processes for preparing same via tiotropium bicarbonate reacted with an acid
DE102005030733A1 (en) 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg New drug combinations for the treatment of respiratory diseases containing long-acting beta-2 agonists and at least one other active ingredient
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ES2530991T3 (en) 2005-08-15 2015-03-09 Boehringer Ingelheim Int Procedure for obtaining betamimetics
US20070086957A1 (en) 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
US7423146B2 (en) 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
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CA2627729A1 (en) * 2005-12-19 2007-07-05 Sicor Inc. Novel forms of tiotropium bromide and processes for preparation thereof
MX2007009987A (en) * 2005-12-19 2007-10-02 Sicor Inc Pure and stable tiotropium bromide.
ME01205B (en) * 2006-01-04 2013-03-20 Boehringer Ingelheim Int Use of tiotropium salts in the treatment of moderate persistent asthma
MX2007012313A (en) 2006-04-19 2007-11-21 Boehringer Ingelheim Int Dihydrothienopyrimidines for the treatment of inflammatory diseases.
EP1847543A1 (en) 2006-04-19 2007-10-24 Boehringer Ingelheim Pharma GmbH & Co. KG Dihydrothienopyrimidines for the treatment of inflammatory diseases
US20080051582A1 (en) 2006-07-10 2008-02-28 Sicor Inc. Process for the preparation of tiotropium bromide
EP2051714B1 (en) 2006-08-07 2011-04-13 Boehringer Ingelheim International GmbH Drug combinations for the treatment of respiratory tract diseases
UY30550A1 (en) 2006-08-22 2008-03-31 Boehringer Ingelheim Int NEW BETA-AGANISTAS ENANTIOMÉRICAMENTE PUROS, PROCEDURES FOR ITS PREPARATION AND ITS USE AS MEDICATIONS
EP1923393A1 (en) * 2006-11-17 2008-05-21 Boehringer Ingelheim Pharma GmbH & Co. KG Crystalline form of tiotropium bromide and urea
EP1925295A1 (en) 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stable powder formulation containing a new antichinolinergic agent
GB0716026D0 (en) * 2007-08-16 2007-09-26 Norton Healthcare Ltd An inhalable medicament
WO2009050248A1 (en) 2007-10-19 2009-04-23 Boehringer Ingelheim International Gmbh Substituted piperidino-dihydrothienopyrimidines
EP2093219A1 (en) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Crystalline enantiomer free salt form of a betamimetic and its use as medicine
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ES2551557T3 (en) 2008-12-19 2015-11-19 Boehringer Ingelheim International Gmbh Cyclic pyrimidin-4-carboxamides as CCR2 receptor antagonists for the treatment of inflammations, asthma and COPD
EP2201934A1 (en) 2008-12-23 2010-06-30 CHIESI FARMACEUTICI S.p.A. Tiotropium aerosol formulation products with improved chemical stability
EP2403851B1 (en) 2009-03-06 2015-06-17 Mahmut Bilgic New crystalline forms of tiotropium bromide
WO2011015883A1 (en) 2009-08-07 2011-02-10 Generics [Uk] Limited Dichloromethane solvate of tiotropium bromide and its use
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EP2513086B1 (en) 2009-12-17 2015-04-29 Boehringer Ingelheim International GmbH Novel antagonists for ccr2 and uses thereof
ES2524829T3 (en) 2009-12-17 2014-12-12 Boehringer Ingelheim International Gmbh New CCR2 receptor antagonists and uses thereof
EP2528915B1 (en) 2010-01-29 2015-10-28 Boehringer Ingelheim International GmbH Substituted naphthyridines and their use as syk kinase inhibitors
JP5646736B2 (en) 2010-05-12 2014-12-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Novel CCR2 receptor antagonists, methods for their preparation, and their use as drugs
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Also Published As

Publication number Publication date
OA12403A (en) 2006-04-18
MXPA03003221A (en) 2004-12-03
CN100519558C (en) 2009-07-29
PE20020422A1 (en) 2002-06-28
HU226830B1 (en) 2009-11-30
CZ301841B6 (en) 2010-07-07
AU2002214996B2 (en) 2007-03-15
HUP0301022A3 (en) 2005-12-28
CA2425539C (en) 2007-04-03
NO20031694L (en) 2003-04-11
CR6938A (en) 2004-10-28
NO328465B1 (en) 2010-02-22
RS50218B (en) 2009-07-15
ATE276253T1 (en) 2004-10-15
NZ525733A (en) 2005-01-28
HRP20030276A2 (en) 2005-02-28
EA004381B1 (en) 2004-04-29
DE50103666D1 (en) 2004-10-21
PL366041A1 (en) 2005-01-24
PT1326862E (en) 2004-11-30
UA74215C2 (en) 2005-11-15
KR100823860B1 (en) 2008-04-21
AU1499602A (en) 2002-04-22
MY126931A (en) 2006-10-31
NO20031694D0 (en) 2003-04-11
CN1733761A (en) 2006-02-15
EA200300457A1 (en) 2003-10-30
EP1326862A1 (en) 2003-07-16
HK1086557A1 (en) 2006-09-22
YU27303A (en) 2006-05-25
SK4362003A3 (en) 2003-08-05
UY26962A1 (en) 2002-06-20
EP1326862B1 (en) 2004-09-15
BG66161B1 (en) 2011-09-30
AR034389A1 (en) 2004-02-25
HRP20030276B1 (en) 2006-02-28
PL207870B1 (en) 2011-02-28
ES2228965T3 (en) 2005-04-16
CA2425539A1 (en) 2003-04-11
SI1326862T1 (en) 2005-02-28
AR068527A2 (en) 2009-11-18
ME00243B (en) 2011-05-10
CN1469877A (en) 2004-01-21
AP2003002775A0 (en) 2003-03-31
BG107687A (en) 2003-09-30
WO2002030928A1 (en) 2002-04-18
IS2339B (en) 2008-02-15
EP1468998A1 (en) 2004-10-20
SK287009B6 (en) 2009-09-07
IL155335A (en) 2009-02-11
EE04567B1 (en) 2005-12-15
TR200402579T4 (en) 2004-12-21
SA01220412B1 (en) 2006-11-05
DZ3478A1 (en) 2002-04-18
HUP0301022A2 (en) 2003-10-28
GEP20063905B (en) 2006-08-25
HK1060567A1 (en) 2004-08-13
BR0114584A (en) 2003-08-26
IS6772A (en) 2003-04-09
DK1326862T3 (en) 2004-11-22
TW589313B (en) 2004-06-01
JP2004526668A (en) 2004-09-02
JP3764422B2 (en) 2006-04-05
ECSP034540A (en) 2003-07-25
CN1221549C (en) 2005-10-05
EE200300171A (en) 2003-06-16
KR20030042008A (en) 2003-05-27
MEP40008A (en) 2011-02-10
AP1572A (en) 2006-02-13
ZA200302500B (en) 2004-04-22
EG24142A (en) 2008-08-06
MA25842A1 (en) 2003-07-01
UY34901A (en) 2015-02-27

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