FI20010927A - Menetelmä terapeuttisesti aktiivisen yhdisteen valmistamiseksi - Google Patents

Menetelmä terapeuttisesti aktiivisen yhdisteen valmistamiseksi Download PDF

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Publication number
FI20010927A
FI20010927A FI20010927A FI20010927A FI20010927A FI 20010927 A FI20010927 A FI 20010927A FI 20010927 A FI20010927 A FI 20010927A FI 20010927 A FI20010927 A FI 20010927A FI 20010927 A FI20010927 A FI 20010927A
Authority
FI
Finland
Prior art keywords
preparation
active compound
therapeutically active
therapeutically
compound
Prior art date
Application number
FI20010927A
Other languages
English (en)
Swedish (sv)
Other versions
FI111710B (fi
FI20010927A0 (fi
Inventor
Arja Marketta Kalapudas
Marja Soedervall
Original Assignee
Hormos Medical Oy Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hormos Medical Oy Ltd filed Critical Hormos Medical Oy Ltd
Priority to FI20010927A priority Critical patent/FI111710B/fi
Publication of FI20010927A0 publication Critical patent/FI20010927A0/fi
Priority to CA002443784A priority patent/CA2443784C/en
Priority to US10/474,717 priority patent/US6891070B2/en
Priority to JP2002587388A priority patent/JP4163963B2/ja
Priority to PCT/FI2002/000235 priority patent/WO2002090305A1/en
Priority to EP02708390A priority patent/EP1383724A1/en
Publication of FI20010927A publication Critical patent/FI20010927A/fi
Application granted granted Critical
Publication of FI111710B publication Critical patent/FI111710B/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI20010927A 2001-05-04 2001-05-04 Menetelmä terapeuttisesti aktiivisen yhdisteen valmistamiseksi FI111710B (fi)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FI20010927A FI111710B (fi) 2001-05-04 2001-05-04 Menetelmä terapeuttisesti aktiivisen yhdisteen valmistamiseksi
CA002443784A CA2443784C (en) 2001-05-04 2002-03-21 A new method for the preparation of 2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy}ethanol and its isomers
US10/474,717 US6891070B2 (en) 2001-05-04 2002-03-21 Method for the preparation of 2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy}ethanol and its isomers
JP2002587388A JP4163963B2 (ja) 2001-05-04 2002-03-21 2−{2−[4−(4−クロロ−1,2−ジフェニルブト−1−エニル)フェノキシ]エトキシ}エタノールおよびその異性体の新規製造方法
PCT/FI2002/000235 WO2002090305A1 (en) 2001-05-04 2002-03-21 A new method for the preparation of 2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy}ethanol and its isomers
EP02708390A EP1383724A1 (en) 2001-05-04 2002-03-21 A new method for the preparation of 2- 2- 4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]ethoxy ethanol and its isomers

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20010927A FI111710B (fi) 2001-05-04 2001-05-04 Menetelmä terapeuttisesti aktiivisen yhdisteen valmistamiseksi
FI20010927 2001-05-04

Publications (3)

Publication Number Publication Date
FI20010927A0 FI20010927A0 (fi) 2001-05-04
FI20010927A true FI20010927A (fi) 2002-11-05
FI111710B FI111710B (fi) 2003-09-15

Family

ID=8561118

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20010927A FI111710B (fi) 2001-05-04 2001-05-04 Menetelmä terapeuttisesti aktiivisen yhdisteen valmistamiseksi

Country Status (6)

Country Link
US (1) US6891070B2 (fi)
EP (1) EP1383724A1 (fi)
JP (1) JP4163963B2 (fi)
CA (1) CA2443784C (fi)
FI (1) FI111710B (fi)
WO (1) WO2002090305A1 (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
KR101510646B1 (ko) 2007-02-14 2015-04-10 호르모스 메디칼 리미티드 치료적으로 유용한 트리페닐부텐 유도체의 제조 방법
US7504530B2 (en) * 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
US9321712B2 (en) 2012-10-19 2016-04-26 Fermion Oy Process for the preparation of ospemifene

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77839C (fi) 1982-05-27 1989-05-10 Farmos Oy Foerfarande foer framstaellning av nya terapeutiskt effektiva trifenylalkan- och alkenderivat.
US5491173A (en) 1982-06-25 1996-02-13 Orion-Yhtyma Oy Tri-phenyl alkene derivatives and their preparation and use
TW593256B (en) 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators

Also Published As

Publication number Publication date
FI111710B (fi) 2003-09-15
EP1383724A1 (en) 2004-01-28
WO2002090305A1 (en) 2002-11-14
US6891070B2 (en) 2005-05-10
US20040116538A1 (en) 2004-06-17
JP2004526799A (ja) 2004-09-02
FI20010927A0 (fi) 2001-05-04
CA2443784C (en) 2008-10-14
CA2443784A1 (en) 2002-11-14
JP4163963B2 (ja) 2008-10-08

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Owner name: HORMOS MEDICAL LTD.

Free format text: HORMOS MEDICAL LTD.

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