EE200300442A - Meetod imidasoolühendite valmistamiseks - Google Patents

Meetod imidasoolühendite valmistamiseks

Info

Publication number
EE200300442A
EE200300442A EEP200300442A EEP200300442A EE200300442A EE 200300442 A EE200300442 A EE 200300442A EE P200300442 A EEP200300442 A EE P200300442A EE P200300442 A EEP200300442 A EE P200300442A EE 200300442 A EE200300442 A EE 200300442A
Authority
EE
Estonia
Prior art keywords
preparation
imidazole compounds
imidazole
compounds
Prior art date
Application number
EEP200300442A
Other languages
English (en)
Inventor
Ferdinand Maria Filliers Walter
Laurent Maria Broeckx Rudy
Marcel Herman Leurs Stefan
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE200300442A publication Critical patent/EE200300442A/et
Publication of EE05247B1 publication Critical patent/EE05247B1/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Resins (AREA)
EEP200300442A 2001-03-12 2002-03-05 Meetod imidasoolhendite valmistamiseks EE05247B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200928 2001-03-12
PCT/EP2002/002459 WO2002072574A1 (en) 2001-03-12 2002-03-05 Process for the preparation of imidazole compounds

Publications (2)

Publication Number Publication Date
EE200300442A true EE200300442A (et) 2003-12-15
EE05247B1 EE05247B1 (et) 2009-12-15

Family

ID=8180004

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200300442A EE05247B1 (et) 2001-03-12 2002-03-05 Meetod imidasoolhendite valmistamiseks

Country Status (32)

Country Link
US (1) US6844439B2 (et)
EP (1) EP1373255B1 (et)
JP (1) JP4257698B2 (et)
KR (1) KR100849042B1 (et)
CN (1) CN1246318C (et)
AR (1) AR035944A1 (et)
AT (1) ATE287882T1 (et)
AU (1) AU2002253101B2 (et)
BR (1) BRPI0208075B8 (et)
CA (1) CA2438421C (et)
CZ (1) CZ300622B6 (et)
DE (1) DE60202755T2 (et)
DK (1) DK1373255T3 (et)
EA (1) EA006770B1 (et)
EE (1) EE05247B1 (et)
ES (1) ES2236505T3 (et)
HK (1) HK1063315A1 (et)
HR (1) HRP20030695B1 (et)
HU (1) HU230282B1 (et)
IL (2) IL157839A0 (et)
MX (1) MXPA03008205A (et)
MY (1) MY124838A (et)
NO (1) NO324954B1 (et)
NZ (1) NZ528620A (et)
PL (1) PL208238B1 (et)
PT (1) PT1373255E (et)
SI (1) SI1373255T1 (et)
SK (1) SK287807B6 (et)
TW (1) TWI249532B (et)
UA (1) UA74871C2 (et)
WO (1) WO2002072574A1 (et)
ZA (1) ZA200307117B (et)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2291455T3 (es) 2001-03-12 2008-03-01 Avanir Pharmaceuticals Compuestos de bencimidazol para modular ige e inhibir la proliferacion celular.
TWI276631B (en) 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
JP2007538004A (ja) * 2004-03-18 2007-12-27 ザ ブライハム アンド ウイメンズ ホスピタル, インコーポレイテッド シヌクレイノパチーを治療する方法
US7524961B2 (en) 2004-05-03 2009-04-28 Janssen Pharmaceutica, N.V. Diastereoselective addition of lithiated N-methylimidazole on sulfinimines
JP4917022B2 (ja) * 2004-05-03 2012-04-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 6−ブロモ−4−(3−クロロフェニル)−2−メトキシ−キノリンを用いるジアステレオ選択的合成方法
ATE397600T1 (de) 2004-05-03 2008-06-15 Janssen Pharmaceutica Nv Diastereoselektives syntheseverfahren zur herstellung vn imidazolverbindungen
EP1968591A4 (en) 2005-12-23 2010-02-17 Link Medicine Corp TREATMENT OF SYNUCLEINOPATHIES
US8232402B2 (en) * 2008-03-12 2012-07-31 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
KR101044430B1 (ko) * 2009-09-25 2011-06-27 듀오백코리아 주식회사 요추받이를 포함하는 의자의 등 지지 장치
KR101107900B1 (ko) * 2009-10-21 2012-01-25 성용기업 주식회사 의자용 허리지지장치
PT3277842T (pt) 2015-08-17 2019-09-05 Kura Oncology Inc Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase
EP3838275A1 (en) 2016-11-03 2021-06-23 Kura Oncology, Inc. Farnesyltransferase inhibitors for use in methods of treating cancer
US10954210B2 (en) 2016-12-08 2021-03-23 Hangzhou Solipharma Co., Ltd. Crystal form of tipifarnib and preparation method and pharmaceutical composition thereof
AU2019270163A1 (en) * 2018-05-18 2020-12-03 Kura Oncology, Inc. Synthesis of tipifarnib

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW349948B (en) 1995-10-31 1999-01-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 2-quinolone derivatives
SI1162201T1 (sl) * 1995-12-08 2006-08-31 Janssen Pharmaceutica Nv (Imidazol-5-il)metil-2-kinolinonski derivati kot inhibitorji farnezil protein transferaze
TW591030B (en) 1997-03-10 2004-06-11 Janssen Pharmaceutica Nv Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles
CA2288140C (en) 1997-04-25 2007-04-03 Janssen Pharmaceutica N.V. Farnesyltransferase inhibiting quinazolinones
JP3495706B2 (ja) * 1998-08-27 2004-02-09 ファイザー・プロダクツ・インク 抗癌薬として有用なアルキニル置換キノリン−2−オン誘導体
ES2237125T3 (es) 1998-08-27 2005-07-16 Pfizer Products Inc. Derivados de quinolin-2-ona utiles como agentes anticancerigenos.

Also Published As

Publication number Publication date
CN1496363A (zh) 2004-05-12
CZ300622B6 (cs) 2009-07-01
NO20034003L (no) 2003-10-22
WO2002072574A1 (en) 2002-09-19
EA200300998A1 (ru) 2004-02-26
MY124838A (en) 2006-07-31
US20040138256A1 (en) 2004-07-15
SK12462003A3 (sk) 2004-06-08
MXPA03008205A (es) 2004-01-29
BRPI0208075B8 (pt) 2021-05-25
KR20030079971A (ko) 2003-10-10
HK1063315A1 (en) 2004-12-24
ZA200307117B (en) 2004-09-13
CA2438421A1 (en) 2002-09-19
PT1373255E (pt) 2005-05-31
HRP20030695B1 (en) 2011-07-31
NO20034003D0 (no) 2003-09-10
HRP20030695A2 (en) 2005-02-28
SI1373255T1 (et) 2005-08-31
SK287807B6 (sk) 2011-10-04
HUP0303443A3 (en) 2012-09-28
TWI249532B (en) 2006-02-21
NO324954B1 (no) 2008-01-14
CZ20032704A3 (en) 2004-03-17
AR035944A1 (es) 2004-07-28
HUP0303443A2 (hu) 2004-01-28
AU2002253101B2 (en) 2007-08-09
CA2438421C (en) 2010-05-18
IL157839A (en) 2008-07-08
PL363263A1 (en) 2004-11-15
IL157839A0 (en) 2004-03-28
EP1373255A1 (en) 2004-01-02
JP2004523575A (ja) 2004-08-05
DE60202755D1 (de) 2005-03-03
EP1373255B1 (en) 2005-01-26
BR0208075A (pt) 2004-03-02
CN1246318C (zh) 2006-03-22
PL208238B1 (pl) 2011-04-29
DK1373255T3 (da) 2005-05-23
EE05247B1 (et) 2009-12-15
KR100849042B1 (ko) 2008-07-29
ES2236505T3 (es) 2005-07-16
ATE287882T1 (de) 2005-02-15
BRPI0208075B1 (pt) 2018-02-14
US6844439B2 (en) 2005-01-18
DE60202755T2 (de) 2006-03-30
JP4257698B2 (ja) 2009-04-22
NZ528620A (en) 2005-01-28
UA74871C2 (en) 2006-02-15
EA006770B1 (ru) 2006-04-28
HU230282B1 (hu) 2015-12-28

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Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20101231