DE60202755D1 - Verfahren zur herstellung von imidazolverbindungen - Google Patents
Verfahren zur herstellung von imidazolverbindungenInfo
- Publication number
- DE60202755D1 DE60202755D1 DE60202755T DE60202755T DE60202755D1 DE 60202755 D1 DE60202755 D1 DE 60202755D1 DE 60202755 T DE60202755 T DE 60202755T DE 60202755 T DE60202755 T DE 60202755T DE 60202755 D1 DE60202755 D1 DE 60202755D1
- Authority
- DE
- Germany
- Prior art keywords
- imidazole compounds
- producing imidazole
- producing
- compounds
- imidazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Resins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01200928 | 2001-03-12 | ||
| EP01200928 | 2001-03-12 | ||
| PCT/EP2002/002459 WO2002072574A1 (en) | 2001-03-12 | 2002-03-05 | Process for the preparation of imidazole compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60202755D1 true DE60202755D1 (de) | 2005-03-03 |
| DE60202755T2 DE60202755T2 (de) | 2006-03-30 |
Family
ID=8180004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60202755T Expired - Lifetime DE60202755T2 (de) | 2001-03-12 | 2002-03-05 | Verfahren zur herstellung von imidazolverbindungen |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6844439B2 (de) |
| EP (1) | EP1373255B1 (de) |
| JP (1) | JP4257698B2 (de) |
| KR (1) | KR100849042B1 (de) |
| CN (1) | CN1246318C (de) |
| AR (1) | AR035944A1 (de) |
| AT (1) | ATE287882T1 (de) |
| AU (1) | AU2002253101B2 (de) |
| BR (1) | BRPI0208075B8 (de) |
| CA (1) | CA2438421C (de) |
| CZ (1) | CZ300622B6 (de) |
| DE (1) | DE60202755T2 (de) |
| DK (1) | DK1373255T3 (de) |
| EA (1) | EA006770B1 (de) |
| EE (1) | EE05247B1 (de) |
| ES (1) | ES2236505T3 (de) |
| HK (1) | HK1063315A1 (de) |
| HR (1) | HRP20030695B1 (de) |
| HU (1) | HU230282B1 (de) |
| IL (2) | IL157839A0 (de) |
| MX (1) | MXPA03008205A (de) |
| MY (1) | MY124838A (de) |
| NO (1) | NO324954B1 (de) |
| NZ (1) | NZ528620A (de) |
| PL (1) | PL208238B1 (de) |
| PT (1) | PT1373255E (de) |
| SI (1) | SI1373255T1 (de) |
| SK (1) | SK287807B6 (de) |
| TW (1) | TWI249532B (de) |
| UA (1) | UA74871C2 (de) |
| WO (1) | WO2002072574A1 (de) |
| ZA (1) | ZA200307117B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1368028E (pt) | 2001-03-12 | 2007-11-26 | Avanir Pharmaceuticals | Compostos de benzimidazole para modulação de ige e inibição da proliferação celular |
| TWI276631B (en) | 2002-09-12 | 2007-03-21 | Avanir Pharmaceuticals | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation |
| WO2004024655A2 (en) | 2002-09-12 | 2004-03-25 | Avanir Pharmaceuticals | Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation |
| US20060106060A1 (en) * | 2004-03-18 | 2006-05-18 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies (Lansbury) |
| JP4917021B2 (ja) * | 2004-05-03 | 2012-04-18 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | スルフィンイミン類に対するリチオ化されたｎ−メチルイミダゾールのジアステレオ選択的付加 |
| DE602005021878D1 (de) * | 2004-05-03 | 2010-07-29 | Janssen Pharmaceutica Nv | Diastereoselektives syntheseverfahren mit 6-brom-4-(3-chlorphenyl)-2-methoxychinolin |
| CA2563807C (en) | 2004-05-03 | 2012-11-20 | Janssen Pharmaceutica N.V. | Diastereoselective synthesis process for the preparation of imidazole compounds |
| WO2007075923A2 (en) | 2005-12-23 | 2007-07-05 | Link Medicine Corporation | Treatment of synucleinopathies |
| WO2009151683A2 (en) * | 2008-03-12 | 2009-12-17 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
| KR101044430B1 (ko) * | 2009-09-25 | 2011-06-27 | 듀오백코리아 주식회사 | 요추받이를 포함하는 의자의 등 지지 장치 |
| KR101107900B1 (ko) * | 2009-10-21 | 2012-01-25 | 성용기업 주식회사 | 의자용 허리지지장치 |
| PT3640345T (pt) | 2015-08-17 | 2021-12-29 | Kura Oncology Inc | Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase |
| DK3534885T3 (da) | 2016-11-03 | 2021-04-12 | Kura Oncology Inc | Farnesyltransferase-inhibitorer til anvendelse i behandling af kræft |
| WO2018103027A1 (zh) | 2016-12-08 | 2018-06-14 | 杭州领业医药科技有限公司 | 替吡法尼的晶型及其制备方法及药物组合物 |
| MX2020012305A (es) * | 2018-05-18 | 2021-03-25 | Kura Oncology Inc | Sintesis de tipifarnib. |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW349948B (en) | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
| TR199800825T2 (xx) | 1995-12-08 | 1998-08-21 | Janssen Pharmaceutica N.V. | Farnesil protein transferini inhibe eden (imidazol-5-il) metil-2-kinolinon t�revleri. |
| TW591030B (en) | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| CN1094937C (zh) * | 1997-04-25 | 2002-11-27 | 詹森药业有限公司 | 具抑制法呢基转化酶作用的喹唑啉酮类 |
| JP3494409B2 (ja) | 1998-08-27 | 2004-02-09 | ファイザー・プロダクツ・インク | 抗がん剤として有用なアルキニル置換キノリン−２−オン誘導体 |
| SK2442001A3 (en) * | 1998-08-27 | 2002-10-08 | Pfizer Prod Inc | Alkynyl-substituted quinolin-2-ones, pharmaceutical compositions, their use in the treatment and method for producing thereof |
-
2002
- 2002-03-05 DK DK02722184T patent/DK1373255T3/da active
- 2002-03-05 AU AU2002253101A patent/AU2002253101B2/en not_active Expired
- 2002-03-05 HU HU0303443A patent/HU230282B1/hu unknown
- 2002-03-05 KR KR1020037010091A patent/KR100849042B1/ko active IP Right Grant
- 2002-03-05 PT PT02722184T patent/PT1373255E/pt unknown
- 2002-03-05 EA EA200300998A patent/EA006770B1/ru not_active IP Right Cessation
- 2002-03-05 MX MXPA03008205A patent/MXPA03008205A/es active IP Right Grant
- 2002-03-05 NZ NZ528620A patent/NZ528620A/en not_active IP Right Cessation
- 2002-03-05 SK SK1246-2003A patent/SK287807B6/sk unknown
- 2002-03-05 SI SI200230100T patent/SI1373255T1/xx unknown
- 2002-03-05 AT AT02722184T patent/ATE287882T1/de active
- 2002-03-05 CZ CZ20032704A patent/CZ300622B6/cs not_active IP Right Cessation
- 2002-03-05 IL IL15783902A patent/IL157839A0/xx unknown
- 2002-03-05 CA CA2438421A patent/CA2438421C/en not_active Expired - Lifetime
- 2002-03-05 PL PL363263A patent/PL208238B1/pl unknown
- 2002-03-05 EE EEP200300442A patent/EE05247B1/xx unknown
- 2002-03-05 JP JP2002571490A patent/JP4257698B2/ja not_active Expired - Lifetime
- 2002-03-05 EP EP02722184A patent/EP1373255B1/de not_active Expired - Lifetime
- 2002-03-05 CN CNB02806335XA patent/CN1246318C/zh not_active Expired - Lifetime
- 2002-03-05 ES ES02722184T patent/ES2236505T3/es not_active Expired - Lifetime
- 2002-03-05 DE DE60202755T patent/DE60202755T2/de not_active Expired - Lifetime
- 2002-03-05 WO PCT/EP2002/002459 patent/WO2002072574A1/en active IP Right Grant
- 2002-03-05 BR BR0208075-3 patent/BRPI0208075B8/pt not_active IP Right Cessation
- 2002-03-05 US US10/471,215 patent/US6844439B2/en not_active Expired - Lifetime
- 2002-03-11 AR ARP020100873A patent/AR035944A1/es active IP Right Grant
- 2002-03-11 TW TW091104444A patent/TWI249532B/zh not_active IP Right Cessation
- 2002-03-11 MY MYPI20020866A patent/MY124838A/en unknown
- 2002-05-03 UA UA2003087776A patent/UA74871C2/uk unknown
-
2003
- 2003-09-01 HR HR20030695A patent/HRP20030695B1/xx not_active IP Right Cessation
- 2003-09-10 IL IL157839A patent/IL157839A/en unknown
- 2003-09-10 NO NO20034003A patent/NO324954B1/no not_active IP Right Cessation
- 2003-09-11 ZA ZA200307117A patent/ZA200307117B/en unknown
-
2004
- 2004-08-12 HK HK04106065A patent/HK1063315A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |