DE69838992T2 - Öl-in-Wasser Emulsionen mit Saponinen - Google Patents
Öl-in-Wasser Emulsionen mit Saponinen Download PDFInfo
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- DE69838992T2 DE69838992T2 DE1998638992 DE69838992T DE69838992T2 DE 69838992 T2 DE69838992 T2 DE 69838992T2 DE 1998638992 DE1998638992 DE 1998638992 DE 69838992 T DE69838992 T DE 69838992T DE 69838992 T2 DE69838992 T2 DE 69838992T2
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9718902.1A GB9718902D0 (en) | 1997-09-05 | 1997-09-05 | Vaccine |
| GB9718902 | 1997-09-05 | ||
| GBGB9720982.9A GB9720982D0 (en) | 1997-10-02 | 1997-10-02 | Vaccine |
| GB9720982 | 1997-10-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69838992D1 DE69838992D1 (de) | 2008-02-21 |
| DE69838992T2 true DE69838992T2 (de) | 2008-12-24 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| DE1998638992 Expired - Lifetime DE69838992T2 (de) | 1997-09-05 | 1998-09-02 | Öl-in-Wasser Emulsionen mit Saponinen |
| DE1998615692 Expired - Lifetime DE69815692T2 (de) | 1997-09-05 | 1998-09-02 | Öl in wasser emulsionen mit saponinen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE1998615692 Expired - Lifetime DE69815692T2 (de) | 1997-09-05 | 1998-09-02 | Öl in wasser emulsionen mit saponinen |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7323182B2 (enExample) |
| EP (2) | EP1009382B1 (enExample) |
| JP (1) | JP4426091B2 (enExample) |
| AU (1) | AU1145699A (enExample) |
| CA (1) | CA2302554C (enExample) |
| DE (2) | DE69838992T2 (enExample) |
| ES (2) | ES2201551T3 (enExample) |
| WO (1) | WO1999011241A1 (enExample) |
Families Citing this family (290)
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| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| DE69737413T2 (de) | 1996-01-04 | 2007-10-31 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Bakterioferritin aus helicobacter pylori |
| US6913749B2 (en) | 1998-11-02 | 2005-07-05 | Resistentia Pharmaceuticals Ab | Immunogenic polypeptides for inducing anti-self IgE responses |
| EP1574210B1 (en) | 1999-02-26 | 2016-04-06 | Novartis Vaccines and Diagnostics, Inc. | Microemulsions with adsorbed macromolecules |
| CN1365286A (zh) * | 1999-06-22 | 2002-08-21 | 希龙公司 | 治疗慢性乙型肝炎病毒感染的方法 |
| GB9915204D0 (en) * | 1999-06-29 | 1999-09-01 | Smithkline Beecham Biolog | Vaccine |
| GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
| DE60039715D1 (de) * | 1999-11-19 | 2008-09-11 | Csl Ltd | Hcv-impfstoff zusammensetzungen |
| IT1307281B1 (it) * | 1999-11-25 | 2001-10-30 | Simonelli Giuseppe | Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, |
| PT2266603E (pt) | 2000-10-18 | 2012-11-02 | Glaxosmithkline Biolog Sa | Vacinas tumorais |
| ES2330083T3 (es) | 2000-10-27 | 2009-12-04 | Novartis Vaccines And Diagnostics S.R.L. | Acidos nucleicos y proteinas de estreptococos de los grupos a y b. |
| EP2336368A1 (en) | 2000-12-07 | 2011-06-22 | Novartis Vaccines and Diagnostics, Inc. | Endogenous retroviruses up-regulated in prostate cancer |
| MY134424A (en) | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| US8481043B2 (en) | 2001-06-22 | 2013-07-09 | Cpex Pharmaceuticals, Inc. | Nasal immunization |
| CZ20033515A3 (cs) | 2001-06-29 | 2005-01-12 | Chiron Corporation | Kompozice vakcíny HCV E1E2 |
| GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
| US20030138434A1 (en) * | 2001-08-13 | 2003-07-24 | Campbell Robert L. | Agents for enhancing the immune response |
| US20030119774A1 (en) * | 2001-09-25 | 2003-06-26 | Marianna Foldvari | Compositions and methods for stimulating an immune response |
| US7501134B2 (en) | 2002-02-20 | 2009-03-10 | Novartis Vaccines And Diagnostics, Inc. | Microparticles with adsorbed polypeptide-containing molecules |
| GB0210682D0 (en) * | 2002-05-09 | 2002-06-19 | Glaxosmithkline Biolog Sa | Novel use |
| AU2008200068B2 (en) * | 2002-06-10 | 2009-10-29 | Novartis Ag | Combinations comprising epothilones and pharmaceutical uses thereof |
| ATE545651T1 (de) | 2002-06-13 | 2012-03-15 | Novartis Vaccines & Diagnostic | Vektoren zur expression von hml-2-polypeptiden |
| JP4726485B2 (ja) * | 2002-08-02 | 2011-07-20 | 大日本住友製薬株式会社 | 細菌細胞壁骨格成分製剤 |
| HRP20090271A2 (en) * | 2002-08-26 | 2009-11-30 | Pfizer Products Inc. | Vaccine for respiratory and reproductive system infections in cattle |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| MXPA05003863A (es) | 2002-10-11 | 2005-09-08 | Chiron Srl | Vacunas polipeptidicas para amplia proteccion contra lineas hipervirulentas de meningococos. |
| PL376792A1 (pl) | 2002-10-23 | 2006-01-09 | Glaxosmithkline Biologicals S.A. | Sposoby szczepienia przeciwko malarii |
| ATE466875T1 (de) | 2002-11-15 | 2010-05-15 | Novartis Vaccines & Diagnostic | Unerwartete oberflächenproteine in neisseria meningitidis |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| JP2006520746A (ja) | 2002-12-27 | 2006-09-14 | カイロン コーポレイション | リン脂質を含む免疫原性組成物 |
| JP4827726B2 (ja) | 2003-01-30 | 2011-11-30 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 複数の髄膜炎菌血清群に対する注射可能ワクチン |
| WO2004087153A2 (en) | 2003-03-28 | 2004-10-14 | Chiron Corporation | Use of organic compounds for immunopotentiation |
| CA2521051C (en) | 2003-04-04 | 2012-03-20 | Pfizer Products Inc. | Microfluidized oil-in-water emulsions and vaccine compositions |
| GB0308198D0 (en) | 2003-04-09 | 2003-05-14 | Chiron Srl | ADP-ribosylating bacterial toxin |
| ATE437633T2 (de) | 2003-06-02 | 2009-08-15 | Novartis Vaccines & Diagnostic | Immunogene zusammensetzungen auf basis von biologisch abbaubaren mikroteilchen enthaltend ein diphtherie- und ein tetanustoxoid |
| US20060035242A1 (en) | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
| GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
| ES2397923T3 (es) | 2003-10-02 | 2013-03-12 | Novartis Ag | Vacunas líquidas para múltiples serogrupos meningocócicos |
| DE202005022108U1 (de) | 2004-03-09 | 2013-11-12 | Novartis Vaccines And Diagnostics, Inc. | Influenza-Virus-Impfstoffe |
| KR20110132416A (ko) * | 2004-04-05 | 2011-12-07 | 화이자 프로덕츠 인코포레이티드 | 미세유체화된 수중유 유화액 및 백신 조성물 |
| EP1741438A4 (en) * | 2004-04-22 | 2009-08-26 | Dainippon Sumitomo Pharma Co | PHARMACEUTICAL PREPARATION CONTAINING SKELETAL COMPONENT OF BACTERIAL CELL WALL |
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| NZ550533A (en) | 2004-04-30 | 2010-02-26 | Novartis Vaccines & Diagnostic | Meningococcal conjugate vaccination comprising N. meningitidis and diphtheria toxin |
| GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| WO2006078294A2 (en) | 2004-05-21 | 2006-07-27 | Novartis Vaccines And Diagnostics Inc. | Alphavirus vectors for respiratory pathogen vaccines |
| EP2583678A3 (en) | 2004-06-24 | 2013-11-13 | Novartis Vaccines and Diagnostics, Inc. | Small molecule immunopotentiators and assays for their detection |
| JP2008504292A (ja) | 2004-06-24 | 2008-02-14 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド | 免疫増強用の化合物 |
| CA2575548A1 (en) | 2004-07-29 | 2006-07-27 | John L. Telford | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
| GB0417494D0 (en) | 2004-08-05 | 2004-09-08 | Glaxosmithkline Biolog Sa | Vaccine |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| EP1855715B1 (en) | 2005-01-27 | 2013-03-13 | Children's Hospital & Research Center at Oakland | Gna1870-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis |
| GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
| GB0503337D0 (en) | 2005-02-17 | 2005-03-23 | Glaxosmithkline Biolog Sa | Compositions |
| NZ561042A (en) | 2005-02-18 | 2011-03-31 | Novartis Vaccines & Diagnostic | Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli - SEQ ID: 7052 |
| EP2298795A1 (en) | 2005-02-18 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Immunogens from uropathogenic escherichia coli |
| GB0504436D0 (en) | 2005-03-03 | 2005-04-06 | Glaxosmithkline Biolog Sa | Vaccine |
| KR20160064249A (ko) * | 2005-03-23 | 2016-06-07 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Ｃｄ4 ｔ－세포 및/또는 개선된 ｂ－메모리 세포 반응을 유도하는 인플루엔자 바이러스 및 수중유 에멀젼 애주번트의 용도 |
| GB0513421D0 (en) | 2005-06-30 | 2005-08-03 | Glaxosmithkline Biolog Sa | Vaccines |
| JP4667507B2 (ja) * | 2005-10-07 | 2011-04-13 | ファイザー・プロダクツ・インク | イヌインフルエンザを治療するワクチンおよび方法 |
| JP2009511636A (ja) | 2005-10-18 | 2009-03-19 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド | アルファウイルスレプリコン粒子による粘膜免疫および全身免疫 |
| US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
| ES2792398T3 (es) | 2005-11-04 | 2020-11-11 | Seqirus Uk Ltd | Vacunas adyuvantadas con antígenos de no virión preparadas a partir de virus de la gripe cultivados en cultivo celular |
| GB0522765D0 (en) | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
| US7527801B2 (en) | 2005-11-22 | 2009-05-05 | Novartis Vaccines And Diagnostics, Inc. | Norovirus and Sapovirus antigens |
| GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| DK2384765T3 (en) | 2005-12-22 | 2017-01-09 | Glaxosmithkline Biologicals Sa | Vaccine against Streptococcus pneumoniae. |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| US8173657B2 (en) | 2006-03-23 | 2012-05-08 | Novartis Ag | Imidazoquinoxaline compounds as immunomodulators |
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| US10138279B2 (en) | 2006-04-13 | 2018-11-27 | Regents Of The University Of Michigan | Compositions and methods for Bacillus anthracis vaccination |
| US9839685B2 (en) | 2006-04-13 | 2017-12-12 | The Regents Of The University Of Michigan | Methods of inducing human immunodeficiency virus-specific immune responses in a host comprising nasally administering compositions comprising a naonemulsion and recombinant GP120 immunogen |
| PT2054431E (pt) | 2006-06-09 | 2011-11-03 | Novartis Ag | Confórmeros de adesinas bacterianas |
| PL2043682T3 (pl) | 2006-07-17 | 2014-09-30 | Glaxosmithkline Biologicals Sa | Szczepionka przeciw grypie |
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| US9452209B2 (en) | 2007-04-20 | 2016-09-27 | Glaxosmithkline Biologicals Sa | Influenza vaccine |
| EP2687228B1 (en) | 2007-06-26 | 2017-07-19 | GlaxoSmithKline Biologicals S.A. | Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates |
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| SU991634A1 (ru) * | 1980-06-05 | 1995-06-09 | Всесоюзный научно-исследовательский ящурный институт | Способ приготовления противовирусных вакцин |
| JPS591405A (ja) * | 1982-06-28 | 1984-01-06 | Shiseido Co Ltd | 乳化組成物 |
| US5057540A (en) * | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| GB8819209D0 (en) * | 1988-08-12 | 1988-09-14 | Research Corp Ltd | Polypeptide & dna encoding same |
| DK0454735T3 (da) * | 1989-01-23 | 1996-10-07 | Auspharm Int Ltd | Vaccine sammensætning |
| US5178862A (en) * | 1989-12-01 | 1993-01-12 | Parhelion Corporation | Canine distemper virus vaccine and method of preparation |
| BR9206310A (pt) | 1991-07-25 | 1995-04-25 | Idec Pharma Corp | Indução de respostas citotóxicas de linfócitos T. |
| FR2713906B1 (fr) | 1993-12-20 | 1996-08-30 | Moulinex Sa | Distributeur automatique de mouture. |
| GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| JPH08605A (ja) | 1994-06-16 | 1996-01-09 | Hitachi Medical Corp | Ｘ線断層像撮像装置 |
| JP3308397B2 (ja) | 1994-07-07 | 2002-07-29 | 住友ベークライト株式会社 | 半導体封止用エポキシ樹脂組成物 |
| UA56132C2 (uk) * | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| EP0879060B1 (en) * | 1996-02-09 | 2008-03-26 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Vaccines against varicella zoster virus gene 63 product |
| GB9718901D0 (en) * | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
-
1998
- 1998-09-02 EP EP19980954264 patent/EP1009382B1/en not_active Expired - Lifetime
- 1998-09-02 JP JP2000508344A patent/JP4426091B2/ja not_active Expired - Fee Related
- 1998-09-02 DE DE1998638992 patent/DE69838992T2/de not_active Expired - Lifetime
- 1998-09-02 CA CA 2302554 patent/CA2302554C/en not_active Expired - Fee Related
- 1998-09-02 DE DE1998615692 patent/DE69815692T2/de not_active Expired - Lifetime
- 1998-09-02 AU AU11456/99A patent/AU1145699A/en not_active Abandoned
- 1998-09-02 ES ES98954264T patent/ES2201551T3/es not_active Expired - Lifetime
- 1998-09-02 ES ES02018002T patent/ES2298316T3/es not_active Expired - Lifetime
- 1998-09-02 WO PCT/EP1998/005715 patent/WO1999011241A1/en not_active Ceased
- 1998-09-02 EP EP20020018002 patent/EP1279401B1/en not_active Expired - Lifetime
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2002
- 2002-05-06 US US10/139,815 patent/US7323182B2/en not_active Expired - Fee Related
-
2008
- 2008-01-28 US US12/020,719 patent/US20080160047A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69815692T2 (de) | 2004-04-29 |
| EP1009382B1 (en) | 2003-06-18 |
| US7323182B2 (en) | 2008-01-29 |
| JP2001514208A (ja) | 2001-09-11 |
| DE69838992D1 (de) | 2008-02-21 |
| JP4426091B2 (ja) | 2010-03-03 |
| ES2201551T3 (es) | 2004-03-16 |
| AU1145699A (en) | 1999-03-22 |
| ES2298316T3 (es) | 2008-05-16 |
| CA2302554A1 (en) | 1999-03-11 |
| DE69815692D1 (de) | 2003-07-24 |
| EP1279401A1 (en) | 2003-01-29 |
| US20080160047A1 (en) | 2008-07-03 |
| CA2302554C (en) | 2007-04-10 |
| EP1279401B1 (en) | 2008-01-09 |
| US20030095974A1 (en) | 2003-05-22 |
| WO1999011241A1 (en) | 1999-03-11 |
| EP1009382A1 (en) | 2000-06-21 |
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