SG10201706671WA - Pseudomonas antigens and antigen combinations - Google Patents

Pseudomonas antigens and antigen combinations

Info

Publication number
SG10201706671WA
SG10201706671WA SG10201706671WA SG10201706671WA SG10201706671WA SG 10201706671W A SG10201706671W A SG 10201706671WA SG 10201706671W A SG10201706671W A SG 10201706671WA SG 10201706671W A SG10201706671W A SG 10201706671WA SG 10201706671W A SG10201706671W A SG 10201706671WA
Authority
SG
Singapore
Prior art keywords
antigen combinations
pseudomonas antigens
pseudomonas
antigens
antigen
Prior art date
Application number
SG10201706671WA
Inventor
Vega Masignani
Maria Scarselli
Roberto Petracca
Irene Bianconi
Alessandra Bragonzi
Franco Beatriz Alcala'
Original Assignee
Glaxosmithkline Biologicals Sa
Ospedale San Raffaele Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa, Ospedale San Raffaele Srl filed Critical Glaxosmithkline Biologicals Sa
Publication of SG10201706671WA publication Critical patent/SG10201706671WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/104Pseudomonadales, e.g. Pseudomonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087Polysaccharides; Lipopolysaccharides [LPS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
SG10201706671WA 2012-11-30 2013-11-27 Pseudomonas antigens and antigen combinations SG10201706671WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB201221638 2012-11-30

Publications (1)

Publication Number Publication Date
SG10201706671WA true SG10201706671WA (en) 2017-09-28

Family

ID=49681020

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201504258RA SG11201504258RA (en) 2012-11-30 2013-11-27 Pseudomonas antigens and antigen combinations
SG10201706671WA SG10201706671WA (en) 2012-11-30 2013-11-27 Pseudomonas antigens and antigen combinations

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201504258RA SG11201504258RA (en) 2012-11-30 2013-11-27 Pseudomonas antigens and antigen combinations

Country Status (24)

Country Link
US (3) US9987344B2 (en)
EP (2) EP2925355B1 (en)
JP (2) JP6340011B2 (en)
KR (1) KR20150100665A (en)
CN (2) CN105142666A (en)
AU (2) AU2013351182C1 (en)
BR (1) BR112015012762A2 (en)
CA (1) CA2892688A1 (en)
CY (1) CY1119912T1 (en)
DK (1) DK2925355T3 (en)
ES (2) ES2656510T3 (en)
HR (1) HRP20180039T1 (en)
HU (1) HUE036158T2 (en)
IL (2) IL238987B (en)
LT (1) LT2925355T (en)
MX (2) MX366876B (en)
NO (1) NO2925355T3 (en)
PL (1) PL2925355T3 (en)
PT (1) PT2925355T (en)
RS (1) RS56886B1 (en)
RU (2) RU2018137673A (en)
SG (2) SG11201504258RA (en)
SI (1) SI2925355T1 (en)
WO (1) WO2014083060A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013007146A (en) * 2010-12-23 2013-11-01 Intercell Austria Ag Oprf/i agents and their use in hospitalized and other patients.
EP3317295B1 (en) * 2015-07-04 2022-05-18 Evaxion Biotech A/S Proteins and nucleic acids useful in vaccines targeting pseudomonas aeruginosa
CN105732778A (en) * 2016-03-02 2016-07-06 中国人民解放军第三军医大学 Pseudomonas aeruginosa recombinant protein OprL as well as preparation method and application thereof
CN110922455B (en) * 2019-12-28 2023-01-13 重庆艾力彼生物科技有限公司 Pseudomonas aeruginosa vaccine recombinant protein repILA-FliC, and preparation method and application thereof

Family Cites Families (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4057685A (en) 1972-02-02 1977-11-08 Abbott Laboratories Chemically modified endotoxin immunizing agent
US4356170A (en) 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4673574A (en) 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
SE8205892D0 (en) 1982-10-18 1982-10-18 Bror Morein IMMUNOGENT MEMBRANE PROTEIN COMPLEX, SET FOR PREPARATION AND USE THEREOF
US4459286A (en) 1983-01-31 1984-07-10 Merck & Co., Inc. Coupled H. influenzae type B vaccine
US4663160A (en) 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
US4761283A (en) 1983-07-05 1988-08-02 The University Of Rochester Immunogenic conjugates
US6090406A (en) 1984-04-12 2000-07-18 The Liposome Company, Inc. Potentiation of immune responses with liposomal adjuvants
US5916588A (en) 1984-04-12 1999-06-29 The Liposome Company, Inc. Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
US4882317A (en) 1984-05-10 1989-11-21 Merck & Co., Inc. Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency
US4695624A (en) 1984-05-10 1987-09-22 Merck & Co., Inc. Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency
US4808700A (en) 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
US4680338A (en) 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
US5011828A (en) 1985-11-15 1991-04-30 Michael Goodman Immunostimulating guanine derivatives, compositions and methods
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
DE3718591A1 (en) 1987-06-03 1988-12-15 Behringwerke Ag AEUSSERES MEMBRANE PROTEIN F BY PSEUDOMONAS AERUGINOSA
US5206152A (en) 1988-04-08 1993-04-27 Arch Development Corporation Cloning and expression of early growth regulatory protein genes
US5422120A (en) 1988-05-30 1995-06-06 Depotech Corporation Heterovesicular liposomes
NL8802046A (en) 1988-08-18 1990-03-16 Gen Electric POLYMER MIXTURE WITH POLYESTER AND ALKANE SULFONATE, OBJECTS THEREFORE.
DE3841091A1 (en) 1988-12-07 1990-06-13 Behringwerke Ag SYNTHETIC ANTIGENS, METHOD FOR THEIR PRODUCTION AND THEIR USE
CA2006700A1 (en) 1989-01-17 1990-07-17 Antonello Pessi Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines
EP0454781B1 (en) 1989-01-23 1998-12-16 Chiron Corporation Recombinant cells for therapies of infection and hyperproliferative disorders and preparation thereof
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
HU212924B (en) 1989-05-25 1996-12-30 Chiron Corp Adjuvant formulation comprising a submicron oil droplet emulsion
EP0482068A1 (en) 1989-07-14 1992-04-29 American Cyanamid Company Cytokine and hormone carriers for conjugate vaccines
SE466259B (en) 1990-05-31 1992-01-20 Arne Forsgren PROTEIN D - AN IGD BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE, AND THE USE OF THIS FOR ANALYSIS, VACCINES AND PURPOSE
US5149655A (en) 1990-06-21 1992-09-22 Agracetus, Inc. Apparatus for genetic transformation
DK0872478T3 (en) 1991-03-01 2003-03-31 Minnesota Mining & Mfg Intermediates for the preparation of 1-substituted, 2-substituted 1H-imidazo [4,5-c] quinoline-4-amines
DE69233013T2 (en) 1991-08-20 2004-03-04 The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer ADENOVIRUS MEDIATED GENTRANSFER INTO THE GASTROINTESTINAL TRACT
US5936076A (en) 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
IT1262896B (en) 1992-03-06 1996-07-22 CONJUGATE COMPOUNDS FORMED FROM HEAT SHOCK PROTEIN (HSP) AND OLIGO-POLY-SACCHARIDES, THEIR USE FOR THE PRODUCTION OF VACCINES.
JP3755890B2 (en) 1992-06-25 2006-03-15 スミスクライン・ビーチャム・バイオロジカルス(ソシエテ・アノニム) Adjuvant-containing vaccine composition
GB2269175A (en) 1992-07-31 1994-02-02 Imperial College Retroviral vectors
AU680459B2 (en) 1992-12-03 1997-07-31 Genzyme Corporation Gene therapy for cystic fibrosis
CN1087176C (en) 1993-03-23 2002-07-10 史密斯克莱·比奇曼生物公司 Vaccine compositions containing 3-O deacylated monophosphoryl lipid A
US6015686A (en) 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
ATE437942T1 (en) 1993-09-15 2009-08-15 Novartis Vaccines & Diagnostic RECOMBINANT ALPHAVIRUS VECTORS
WO1995011700A1 (en) 1993-10-29 1995-05-04 Pharmos Corp. Submicron emulsions as vaccine adjuvants
CA2176712C (en) 1993-11-16 2000-05-23 Mantripragada Sankaram Synthetic membrane vesicles with controlled release of encapsulated biologically active substances
GB9326174D0 (en) 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
GB9326253D0 (en) 1993-12-23 1994-02-23 Smithkline Beecham Biolog Vaccines
ATE190657T1 (en) * 1994-12-16 2000-04-15 Chiron Behring Gmbh & Co IMMUNOGENIC HYBRID PROTEIN OPRF-OPRL AVAILABLE FROM MEMBRANE PROTEINS OF PSEUDOMONAS AERUGINOSA
UA56132C2 (en) 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Vaccine composition (variants), method for stabilizing qs21 providing resistance against hydrolysis (variants), method for manufacturing vaccine
GB9513261D0 (en) 1995-06-29 1995-09-06 Smithkline Beecham Biolog Vaccines
US6818222B1 (en) 1997-03-21 2004-11-16 Chiron Corporation Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
US6080725A (en) 1997-05-20 2000-06-27 Galenica Pharmaceuticals, Inc. Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof
GB9713156D0 (en) 1997-06-20 1997-08-27 Microbiological Res Authority Vaccines
ES2298316T3 (en) 1997-09-05 2008-05-16 Glaxosmithkline Biologicals S.A. WATER OIL EMULSIONS CONTAINING SAPONINS.
GB9725084D0 (en) 1997-11-28 1998-01-28 Medeva Europ Ltd Vaccine compositions
EP1053015A2 (en) 1998-02-12 2000-11-22 American Cyanamid Company Pneumococcal and meningococcal vaccines formulated with interleukin-12
US6551795B1 (en) * 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
PL354714A1 (en) 1998-04-09 2004-02-09 Smithkline Beecham Biologicals S.A. Adjuvant compositions
JP2002513773A (en) 1998-05-07 2002-05-14 コリクサ コーポレイション Adjuvant composition and use thereof
US6562798B1 (en) 1998-06-05 2003-05-13 Dynavax Technologies Corp. Immunostimulatory oligonucleotides with modified bases and methods of use thereof
GB9817052D0 (en) 1998-08-05 1998-09-30 Smithkline Beecham Biolog Vaccine
WO2000010599A2 (en) 1998-08-19 2000-03-02 North American Vaccine, Inc. IMMUNOGENIC β-PROPIONAMIDO-LINKED POLYSACCHARIDE PROTEIN CONJUGATE USEFUL AS A VACCINE PRODUCED USING AN N-ACRYLOYLATED POLYSACCHARIDE
EP2266604A3 (en) 1998-10-16 2011-05-11 GlaxoSmithKline Biologicals S.A. Adjuvant systems and vaccines
WO2000033882A1 (en) 1998-12-04 2000-06-15 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services A vi-repa conjugate vaccine for immunization against salmonella typhi
US6551600B2 (en) 1999-02-01 2003-04-22 Eisai Co., Ltd. Immunological adjuvant compounds compositions and methods of use thereof
ES2228467T3 (en) 1999-02-03 2005-04-16 Biosante Pharmaceuticals, Inc. THERAPEUTIC PARTICLES OF CALCIUM PHOSPHATE AND METHODS OF MANUFACTURE AND ITS USE.
WO2000061761A2 (en) 1999-04-09 2000-10-19 Techlab, Inc. Recombinant clostridium toxin a protein carrier for polysaccharide conjugate vaccines
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
EP1221971A2 (en) 1999-09-24 2002-07-17 SmithKline Beecham Biologics SA Use of the combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines
BR0014285A (en) 1999-09-24 2002-05-21 Smithkline Beecham Biolog Adjuvants comprising a polyoxyethylene alkyl ester or ether and at least one nonionic surfactant
RU2245149C2 (en) 1999-09-25 2005-01-27 Юниверсити Оф Айова Рисерч Фаундейшн Immunostimulating nucleic acids
GB0007432D0 (en) 2000-03-27 2000-05-17 Microbiological Res Authority Proteins for use as carriers in conjugate vaccines
US6551759B2 (en) 2000-06-13 2003-04-22 Agfa-Gevaert Direct-to-plate flexographic printing plate precursor
CZ304344B6 (en) 2000-09-11 2014-03-19 Novartis Vaccines & Diagnostics, Inc. Quinolinone derivatives and their use as well as pharmaceutical compositions in which the derivatives are comprised
AU2001294750C1 (en) 2000-09-26 2008-09-18 Idera Pharmaceuticals, Inc. Modulation of immunostimulatory activity of immunostimulatory oligonucleotide analogs by positional chemical changes
AU2002309706A1 (en) 2001-05-11 2002-11-25 Aventis Pasteur, Inc. Novel meningitis conjugate vaccine
US7321033B2 (en) 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
DE60234376D1 (en) 2001-11-27 2009-12-24 Anadys Pharmaceuticals Inc 3-BETA-D-RIBOFURANOSYLTHIAZOLO (4,5-DELTA) PYRIDIMINE NUCLEOSIDE AND ITS USE
NZ535985A (en) 2002-03-29 2007-04-27 Chiron Corp Substituted benzazoles and use thereof as RAF kinase inhibitors
ATE477251T1 (en) 2002-08-23 2010-08-15 Novartis Vaccines & Diagnostic PYRROLE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 INHIBITORS
WO2004060308A2 (en) 2002-12-27 2004-07-22 Chiron Corporation Thiosemicarbazones as anti-virals and immunopotentiators
WO2004064759A2 (en) 2003-01-21 2004-08-05 Chiron Corporation Use of tryptanthrin compounds for immune potentiation
GB0301554D0 (en) 2003-01-23 2003-02-26 Molecularnature Ltd Immunostimulatory compositions
WO2004087153A2 (en) 2003-03-28 2004-10-14 Chiron Corporation Use of organic compounds for immunopotentiation
KR20090051129A (en) 2004-04-05 2009-05-20 화이자 프로덕츠 인코포레이티드 Microfluidized oil-in-water emulsions and vaccine compositions
US20060228369A1 (en) 2005-04-11 2006-10-12 Program For Appropriate Technology In Health Stabilization and preservation of temperature-sensitive vaccines
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
HUE031380T2 (en) 2005-06-27 2017-07-28 Glaxosmithkline Biologicals Sa Process for manufacturing vaccines
US8703095B2 (en) 2005-07-07 2014-04-22 Sanofi Pasteur S.A. Immuno-adjuvant emulsion
FR2896162B1 (en) 2006-01-13 2008-02-15 Sanofi Pasteur Sa EMULSION OIL IN THERMOREVERSIBLE WATER
ES2397714T3 (en) 2006-10-12 2013-03-08 Glaxosmithkline Biologicals S.A. Vaccine comprising an oil-in-water emulsion adjuvant
JP2008133206A (en) * 2006-11-28 2008-06-12 Yokohama City Univ Pharmaceutical composition capable of inducing phylactic ability against pseudomonas aeruginosa
CN101878302A (en) 2007-06-29 2010-11-03 明治制果株式会社 Pseudomonas aeruginosa outer membrane protein PA4710
WO2010107778A1 (en) 2009-03-18 2010-09-23 Wake Forest University Health Sciences Flagellin fusion proteins and use thereof to induce immune responses against pseudomonas aeruginosa
MX2013007146A (en) 2010-12-23 2013-11-01 Intercell Austria Ag Oprf/i agents and their use in hospitalized and other patients.

Also Published As

Publication number Publication date
CY1119912T1 (en) 2018-06-27
IL238987A0 (en) 2015-07-30
SG11201504258RA (en) 2015-07-30
PT2925355T (en) 2018-02-05
CN111249455A (en) 2020-06-09
EP2925355A2 (en) 2015-10-07
JP6340011B2 (en) 2018-06-06
AU2013351182A1 (en) 2015-06-18
SI2925355T1 (en) 2018-04-30
NO2925355T3 (en) 2018-04-14
CA2892688A1 (en) 2014-06-05
US9987344B2 (en) 2018-06-05
AU2018203852B2 (en) 2020-02-27
AU2013351182C1 (en) 2018-11-08
MX2015006791A (en) 2016-01-14
EP3345617A1 (en) 2018-07-11
RU2018137673A (en) 2019-03-22
RU2015125699A (en) 2017-01-11
HUE036158T2 (en) 2018-06-28
AU2013351182B2 (en) 2018-03-08
BR112015012762A2 (en) 2017-09-12
PL2925355T3 (en) 2018-06-29
WO2014083060A2 (en) 2014-06-05
ES2656510T3 (en) 2018-02-27
EP3345617B1 (en) 2020-08-26
US20200360504A1 (en) 2020-11-19
AU2018203852A1 (en) 2018-06-21
IL238987B (en) 2019-08-29
WO2014083060A3 (en) 2014-08-28
CN105142666A (en) 2015-12-09
ES2826555T3 (en) 2021-05-18
IL267657A (en) 2019-08-29
US20180256701A1 (en) 2018-09-13
HRP20180039T1 (en) 2018-04-06
JP2018135388A (en) 2018-08-30
US20150322116A1 (en) 2015-11-12
JP2016502533A (en) 2016-01-28
RS56886B1 (en) 2018-04-30
KR20150100665A (en) 2015-09-02
LT2925355T (en) 2018-03-26
MX366876B (en) 2019-07-29
MX2019008779A (en) 2019-09-10
DK2925355T3 (en) 2018-01-15
EP2925355B1 (en) 2017-11-15

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