DE69434760D1 - Teilchenverabreichung von therapeutischen Mitteln im pulverisierten Zustand - Google Patents

Teilchenverabreichung von therapeutischen Mitteln im pulverisierten Zustand

Info

Publication number
DE69434760D1
DE69434760D1 DE69434760T DE69434760T DE69434760D1 DE 69434760 D1 DE69434760 D1 DE 69434760D1 DE 69434760 T DE69434760 T DE 69434760T DE 69434760 T DE69434760 T DE 69434760T DE 69434760 D1 DE69434760 D1 DE 69434760D1
Authority
DE
Germany
Prior art keywords
therapeutic agents
powdered state
particle administration
particles
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69434760T
Other languages
English (en)
Other versions
DE69434760T2 (de
Inventor
Brian John Bellhouse
David Francis Sarphie
John Christopher Greenford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Powderject Research Ltd
Original Assignee
Powderject Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939307459A external-priority patent/GB9307459D0/en
Priority claimed from GB939318407A external-priority patent/GB9318407D0/en
Priority claimed from GB939321356A external-priority patent/GB9321356D0/en
Priority claimed from GB939326069A external-priority patent/GB9326069D0/en
Application filed by Powderject Research Ltd filed Critical Powderject Research Ltd
Publication of DE69434760D1 publication Critical patent/DE69434760D1/de
Application granted granted Critical
Publication of DE69434760T2 publication Critical patent/DE69434760T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
    • C12N15/895—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection using biolistic methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/42—Reducing noise
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
DE69434760T 1993-04-08 1994-04-08 Teilchenverabreichung von therapeutischen Mitteln im pulverisierten Zustand Expired - Lifetime DE69434760T2 (de)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB939307459A GB9307459D0 (en) 1993-04-08 1993-04-08 Particle delivery apparatus
GB9307459 1993-04-08
GB939318407A GB9318407D0 (en) 1993-09-06 1993-09-06 Particle delivery apparatus
GB9318407 1993-09-06
GB939321356A GB9321356D0 (en) 1993-10-15 1993-10-15 Particle delivery apparatus
GB9321356 1993-10-15
GB939326069A GB9326069D0 (en) 1993-12-21 1993-12-21 Particle delivery apparatus
GB9326069 1993-12-21

Publications (2)

Publication Number Publication Date
DE69434760D1 true DE69434760D1 (de) 2006-07-20
DE69434760T2 DE69434760T2 (de) 2007-05-16

Family

ID=27451010

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69401651T Expired - Lifetime DE69401651T2 (de) 1993-04-08 1994-04-08 Nadellose spritze unter anwendung eines gasstroms mit überschallgeschwindigkeit zur verabreichung von partikeln
DE69434760T Expired - Lifetime DE69434760T2 (de) 1993-04-08 1994-04-08 Teilchenverabreichung von therapeutischen Mitteln im pulverisierten Zustand

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69401651T Expired - Lifetime DE69401651T2 (de) 1993-04-08 1994-04-08 Nadellose spritze unter anwendung eines gasstroms mit überschallgeschwindigkeit zur verabreichung von partikeln

Country Status (32)

Country Link
US (5) US5630796A (de)
EP (4) EP0693119B1 (de)
JP (4) JP3260375B2 (de)
KR (1) KR100332147B1 (de)
CN (1) CN1109102C (de)
AT (2) ATE148497T1 (de)
AU (1) AU674742B2 (de)
BG (1) BG61993B1 (de)
BR (1) BR9406455A (de)
CA (1) CA2159452C (de)
CZ (1) CZ290476B6 (de)
DE (2) DE69401651T2 (de)
DK (2) DK0734737T3 (de)
ES (2) ES2267106T3 (de)
FI (1) FI120671B (de)
GR (1) GR3022939T3 (de)
HK (1) HK1000351A1 (de)
HU (2) HU216308B (de)
LV (1) LV11833B (de)
NO (1) NO314570B1 (de)
NZ (1) NZ263606A (de)
OA (1) OA10234A (de)
PL (1) PL174974B1 (de)
PT (1) PT734737E (de)
RO (1) RO118569B1 (de)
RU (1) RU2129021C1 (de)
SI (2) SI0693119T1 (de)
SK (1) SK283855B6 (de)
TJ (1) TJ248B (de)
TW (2) TW360548B (de)
UA (1) UA41360C2 (de)
WO (1) WO1994024263A1 (de)

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TW360548B (en) 1999-06-11
DE69401651D1 (de) 1997-03-13
ATE148497T1 (de) 1997-02-15
EP0734737B1 (de) 2006-06-07
BR9406455A (pt) 1996-01-02
SI0734737T1 (sl) 2006-10-31
HK1000351A1 (en) 1998-03-06
PL311005A1 (en) 1996-01-22
TJ248B (en) 1999-12-23
US6168587B1 (en) 2001-01-02
JP4430636B2 (ja) 2010-03-10
HU228144B1 (en) 2012-12-28
EP0951917A3 (de) 2000-01-05
EP1637173A3 (de) 2007-09-05
NO314570B1 (no) 2003-04-14
US20070299390A1 (en) 2007-12-27
AU674742B2 (en) 1997-01-09
US7942846B2 (en) 2011-05-17
US6881200B2 (en) 2005-04-19
EP1637173A2 (de) 2006-03-22
SK124895A3 (en) 1997-01-08
HU9502911D0 (en) 1995-12-28
PL174974B1 (pl) 1998-10-30
EP0693119B1 (de) 1997-01-29
CA2159452C (en) 2000-11-21
LV11833A (lv) 1997-08-20
DK0734737T3 (da) 2006-10-09
HU216308B (hu) 1999-06-28
DE69401651T2 (de) 1997-05-15
AU6435194A (en) 1994-11-08
US20050165348A1 (en) 2005-07-28
JPH08509604A (ja) 1996-10-15
US20020188248A1 (en) 2002-12-12
BG100047A (bg) 1996-04-30
EP1637173B1 (de) 2014-05-21
CA2159452A1 (en) 1994-10-27
BG61993B1 (bg) 1998-12-30
CN1109102C (zh) 2003-05-21
NO953994L (no) 1995-10-06
DK0693119T3 (da) 1997-07-28
NZ263606A (en) 1997-08-22
CZ290476B6 (cs) 2002-07-17
CN1120852A (zh) 1996-04-17
LV11833B (en) 1997-12-20
FI120671B (fi) 2010-01-29
ES2267106T3 (es) 2007-03-01
US7618394B2 (en) 2009-11-17
DE69434760T2 (de) 2007-05-16
FI954788A (fi) 1995-10-06
EP0693119A1 (de) 1996-01-24
SI0693119T1 (en) 1997-10-31
GR3022939T3 (en) 1997-06-30
JP2006320737A (ja) 2006-11-30
US5630796A (en) 1997-05-20
JP2002179557A (ja) 2002-06-26
OA10234A (en) 1997-10-07
KR100332147B1 (ko) 2002-08-14
TW404844B (en) 2000-09-11
RO118569B1 (ro) 2003-07-30
ATE329006T1 (de) 2006-06-15
EP0951917A2 (de) 1999-10-27
HUT73516A (en) 1996-08-28
ES2098131T3 (es) 1997-04-16
SK283855B6 (sk) 2004-03-02
EP0734737A3 (de) 1997-03-12
JP3260375B2 (ja) 2002-02-25
UA41360C2 (uk) 2001-09-17
JP2007051160A (ja) 2007-03-01
CZ260895A3 (en) 1996-05-15
NO953994D0 (no) 1995-10-06
WO1994024263A1 (en) 1994-10-27
RU2129021C1 (ru) 1999-04-20
HU9802714D0 (en) 1999-01-28
FI954788A0 (fi) 1995-10-06
PT734737E (pt) 2006-09-29

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