DE602005024502D1 - Anti-glypican-3-antikörper - Google Patents

Anti-glypican-3-antikörper

Info

Publication number
DE602005024502D1
DE602005024502D1 DE602005024502T DE602005024502T DE602005024502D1 DE 602005024502 D1 DE602005024502 D1 DE 602005024502D1 DE 602005024502 T DE602005024502 T DE 602005024502T DE 602005024502 T DE602005024502 T DE 602005024502T DE 602005024502 D1 DE602005024502 D1 DE 602005024502D1
Authority
DE
Germany
Prior art keywords
antibody
glypican
disclosed
agent
cancers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005024502T
Other languages
English (en)
Inventor
Kiyotaka Nakano
Takeshi Yoshino
Jun-Ichi Nezu
Hiroyuki Tsunoda
Tomoyuki Igawa
Hiroko Konishi
Megumi Tanaka
Izumi Sugo
Shigeto Kawai
Takahiro Ishiguro
Yasuko Kinoshita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35784028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE602005024502(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DE602005024502D1 publication Critical patent/DE602005024502D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
DE602005024502T 2004-07-09 2005-07-08 Anti-glypican-3-antikörper Active DE602005024502D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004203637 2004-07-09
PCT/JP2005/013103 WO2006006693A1 (ja) 2004-07-09 2005-07-08 抗グリピカン３抗体

Publications (1)

Publication Number Publication Date
DE602005024502D1 true DE602005024502D1 (de) 2010-12-16

Family

ID=35784028

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005024502T Active DE602005024502D1 (de) 2004-07-09 2005-07-08 Anti-glypican-3-antikörper

Country Status (26)

Country Link
US (3) US7919086B2 (de)
EP (4) EP2314317A3 (de)
JP (3) JP4011100B2 (de)
KR (2) KR101300545B1 (de)
CN (4) CN111925445A (de)
AT (1) ATE486610T1 (de)
AU (1) AU2005256113B2 (de)
BR (1) BRPI0506125B8 (de)
CA (1) CA2544692C (de)
CY (1) CY1111649T1 (de)
DE (1) DE602005024502D1 (de)
DK (1) DK1674111T3 (de)
ES (1) ES2353967T3 (de)
HK (1) HK1092161A1 (de)
IL (1) IL172938A (de)
MX (1) MXPA06002890A (de)
MY (1) MY145073A (de)
NO (1) NO343105B1 (de)
NZ (2) NZ579543A (de)
PL (1) PL1674111T3 (de)
PT (1) PT1674111E (de)
RU (2) RU2427588C2 (de)
SI (1) SI1674111T1 (de)
TW (1) TWI455946B (de)
UA (1) UA94019C2 (de)
WO (1) WO2006006693A1 (de)

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ES2353967T3 (es) 2011-03-08
BRPI0506125B8 (pt) 2021-05-25
CY1111649T1 (el) 2015-10-07
EP1674111A1 (de) 2006-06-28
CN102702353A (zh) 2012-10-03
EP1674111B1 (de) 2010-11-03
NO343105B1 (no) 2018-11-05
CN105820249A (zh) 2016-08-03
UA94019C2 (ru) 2011-04-11
ATE486610T1 (de) 2010-11-15
TWI455946B (zh) 2014-10-11
AU2005256113B2 (en) 2011-02-10
EP2314317A3 (de) 2011-06-29
AU2005256113A8 (en) 2008-09-11
KR20070034448A (ko) 2007-03-28
EP2216046A3 (de) 2010-12-22
IL172938A0 (en) 2006-06-11
HK1092161A1 (en) 2007-02-02
MY145073A (en) 2011-12-15
JPWO2006006693A1 (ja) 2008-05-01
RU2006104842A (ru) 2007-08-27
JP2013039131A (ja) 2013-02-28
KR101413402B1 (ko) 2014-06-27
PL1674111T3 (pl) 2011-04-29
EP1674111A4 (de) 2008-03-19
BRPI0506125B1 (pt) 2019-10-15
AU2005256113A1 (en) 2006-03-30
US7919086B2 (en) 2011-04-05
IL172938A (en) 2013-09-30
US20070190599A1 (en) 2007-08-16
EP2216046A2 (de) 2010-08-11
TW200617022A (en) 2006-06-01
CN1842540A (zh) 2006-10-04
RU2611751C2 (ru) 2017-02-28
EP2898897A2 (de) 2015-07-29
EP2898897A3 (de) 2015-10-14
CA2544692C (en) 2014-04-01
KR20130014698A (ko) 2013-02-08
CA2544692A1 (en) 2006-01-19
NO20063539L (no) 2007-01-09
US20100248359A1 (en) 2010-09-30
PT1674111E (pt) 2010-12-15
JP5715603B2 (ja) 2015-05-07
NZ579543A (en) 2011-07-29
BRPI0506125A (pt) 2006-10-24
JP2009232848A (ja) 2009-10-15
RU2011115845A (ru) 2012-10-27
MXPA06002890A (es) 2006-06-05
CN1842540B (zh) 2012-07-04
KR101300545B1 (ko) 2013-09-02
DK1674111T3 (da) 2011-02-07
EP2314317A2 (de) 2011-04-27
SI1674111T1 (sl) 2011-02-28
JP4011100B2 (ja) 2007-11-21
WO2006006693A1 (ja) 2006-01-19
CN111925445A (zh) 2020-11-13
NZ545720A (en) 2010-01-29

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