DE60031793T2 - Doxorubicin- und daunorubicin-enthaltende, zytotoxische mittel und deren therapeutische anwendung - Google Patents

Doxorubicin- und daunorubicin-enthaltende, zytotoxische mittel und deren therapeutische anwendung Download PDF

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Publication number
DE60031793T2
DE60031793T2 DE60031793T DE60031793T DE60031793T2 DE 60031793 T2 DE60031793 T2 DE 60031793T2 DE 60031793 T DE60031793 T DE 60031793T DE 60031793 T DE60031793 T DE 60031793T DE 60031793 T2 DE60031793 T2 DE 60031793T2
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cell
linker group
binding agent
daunorubicin
group
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Expired - Lifetime
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DE60031793D1 (de
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V. Ravi Newton CHARI
A. Walter Brookline BLATTLER
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Immunogen Inc
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Immunogen Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
DE60031793T 1999-12-29 2000-12-19 Doxorubicin- und daunorubicin-enthaltende, zytotoxische mittel und deren therapeutische anwendung Expired - Lifetime DE60031793T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17349799P 1999-12-29 1999-12-29
US173497P 1999-12-29
PCT/US2000/033276 WO2001049698A1 (en) 1999-12-29 2000-12-19 Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use

Publications (2)

Publication Number Publication Date
DE60031793D1 DE60031793D1 (de) 2006-12-21
DE60031793T2 true DE60031793T2 (de) 2007-08-23

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DE60031793T Expired - Lifetime DE60031793T2 (de) 1999-12-29 2000-12-19 Doxorubicin- und daunorubicin-enthaltende, zytotoxische mittel und deren therapeutische anwendung

Country Status (12)

Country Link
US (1) US6630579B2 (enExample)
EP (1) EP1242438B1 (enExample)
JP (1) JP2003531821A (enExample)
AT (1) ATE344801T1 (enExample)
AU (1) AU767394C (enExample)
CA (1) CA2395660A1 (enExample)
DE (1) DE60031793T2 (enExample)
DK (1) DK1242438T3 (enExample)
ES (1) ES2274823T3 (enExample)
NZ (1) NZ518764A (enExample)
PT (1) PT1242438E (enExample)
WO (1) WO2001049698A1 (enExample)

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