DD248584A5 - Verfahren zur herstellung von (3s)-3-amino-2-oxo-4,4-dimethyl-1-azetidinylsulfat und seinen salzen mit basen - Google Patents
Verfahren zur herstellung von (3s)-3-amino-2-oxo-4,4-dimethyl-1-azetidinylsulfat und seinen salzen mit basen Download PDFInfo
- Publication number
- DD248584A5 DD248584A5 DD86292943A DD29294386A DD248584A5 DD 248584 A5 DD248584 A5 DD 248584A5 DD 86292943 A DD86292943 A DD 86292943A DD 29294386 A DD29294386 A DD 29294386A DD 248584 A5 DD248584 A5 DD 248584A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- amino
- compound
- general formula
- dimethyl
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/18—Salts thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/695,775 US4638061A (en) | 1985-01-28 | 1985-01-28 | [3S(Z)]-2-[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy] acetic acid and intermediate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD248584A5 true DD248584A5 (de) | 1987-08-12 |
Family
ID=24794413
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD86292943A DD248584A5 (de) | 1985-01-28 | 1986-01-28 | Verfahren zur herstellung von (3s)-3-amino-2-oxo-4,4-dimethyl-1-azetidinylsulfat und seinen salzen mit basen |
| DD86286545A DD241600A5 (de) | 1985-01-28 | 1986-01-28 | Verfahren zur herstellung von 4,4-dialkyl-2-azetidinon-verbindungen |
| DD86292942A DD248592A5 (de) | 1985-01-28 | 1986-01-28 | Verfahren zur herstellung der [3s(z)]-2-[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfoxy)-3-azetidinyl]-amino]-2-oxoaethyliden]-aminooxyessigsaeure und ihrer salze |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD86286545A DD241600A5 (de) | 1985-01-28 | 1986-01-28 | Verfahren zur herstellung von 4,4-dialkyl-2-azetidinon-verbindungen |
| DD86292942A DD248592A5 (de) | 1985-01-28 | 1986-01-28 | Verfahren zur herstellung der [3s(z)]-2-[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfoxy)-3-azetidinyl]-amino]-2-oxoaethyliden]-aminooxyessigsaeure und ihrer salze |
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US4638061A (he) |
| JP (2) | JPH0780840B2 (he) |
| KR (1) | KR900000675B1 (he) |
| CN (1) | CN1014894B (he) |
| AR (1) | AR242024A1 (he) |
| AT (1) | AT389511B (he) |
| AU (1) | AU588017B2 (he) |
| BE (1) | BE904121A (he) |
| CA (2) | CA1283924C (he) |
| CH (3) | CH670825A5 (he) |
| CS (1) | CS253740B2 (he) |
| DD (3) | DD248584A5 (he) |
| DE (1) | DE3602347A1 (he) |
| DK (1) | DK39486A (he) |
| EG (1) | EG17682A (he) |
| ES (3) | ES8706112A1 (he) |
| FI (1) | FI85022C (he) |
| FR (1) | FR2576596B1 (he) |
| GB (2) | GB2170201B (he) |
| GR (1) | GR860239B (he) |
| HU (1) | HU196367B (he) |
| IE (2) | IE59629B1 (he) |
| IL (1) | IL77661A (he) |
| IT (1) | IT1190604B (he) |
| LU (1) | LU86262A1 (he) |
| NL (1) | NL8600136A (he) |
| NO (1) | NO170014C (he) |
| NZ (1) | NZ214836A (he) |
| PH (3) | PH22425A (he) |
| PL (3) | PL257668A1 (he) |
| PT (1) | PT81914B (he) |
| RO (1) | RO93483B (he) |
| SE (3) | SE467824B (he) |
| YU (2) | YU45760B (he) |
| ZA (1) | ZA86302B (he) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4751220A (en) * | 1986-12-19 | 1988-06-14 | E. R. Squibb & Sons, Inc. | Crystalline salts of [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy]acetic acid |
| US5143913A (en) * | 1988-04-04 | 1992-09-01 | E. R. Squibb & Sons, Inc. | [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate |
| EP0336667A3 (en) * | 1988-04-04 | 1991-04-10 | E.R. Squibb & Sons, Inc. | [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]-amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate |
| US4973747A (en) * | 1989-08-15 | 1990-11-27 | E. R. Squibb & Sons, Inc. | Process for preparing 3-hydroxy 2-keto acids |
| CN103724330B (zh) * | 2005-12-07 | 2015-08-19 | 巴斯利尔药物股份公司 | 单环-内酰胺类抗生素与β-内酰胺酶抑制剂的有效的联合应用 |
| US10047077B2 (en) | 2016-04-13 | 2018-08-14 | Skyline Antiinfectives, Inc. | Deuterated O-sulfated beta-lactam hydroxamic acids and deuterated N-sulfated beta-lactams |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4337197A (en) * | 1980-10-31 | 1982-06-29 | E. R. Squibb & Sons, Inc. | O-sulfated β-lactam hydroxamic acids and intermediates |
| JPS58113174A (ja) * | 1981-12-26 | 1983-07-05 | Toyama Chem Co Ltd | 新規なアゼチジン誘導体またはその塩類を含有する抗菌剤 |
| JPS58194856A (ja) * | 1982-05-10 | 1983-11-12 | Yamanouchi Pharmaceut Co Ltd | 新規２−アゼチジノン誘導体 |
| JPS58206589A (ja) * | 1982-05-26 | 1983-12-01 | Yamanouchi Pharmaceut Co Ltd | ２−アゼチジノン誘導体 |
| US4565654A (en) * | 1983-03-28 | 1986-01-21 | University Of Notre Dame Du Lac | N-Acyloxy monocyclic β-lactams |
-
1985
- 1985-01-28 US US06/695,775 patent/US4638061A/en not_active Expired - Fee Related
-
1986
- 1986-01-15 ZA ZA86302A patent/ZA86302B/xx unknown
- 1986-01-15 CA CA000499611A patent/CA1283924C/en not_active Expired - Lifetime
- 1986-01-15 GB GB08600825A patent/GB2170201B/en not_active Expired
- 1986-01-15 NZ NZ214836A patent/NZ214836A/xx unknown
- 1986-01-16 YU YU5886A patent/YU45760B/sh unknown
- 1986-01-16 PH PH33290A patent/PH22425A/en unknown
- 1986-01-17 FR FR868600631A patent/FR2576596B1/fr not_active Expired
- 1986-01-17 AU AU52460/86A patent/AU588017B2/en not_active Ceased
- 1986-01-20 FI FI860247A patent/FI85022C/fi not_active IP Right Cessation
- 1986-01-21 IL IL77661A patent/IL77661A/xx not_active IP Right Cessation
- 1986-01-22 LU LU86262A patent/LU86262A1/fr unknown
- 1986-01-22 NL NL8600136A patent/NL8600136A/xx not_active Application Discontinuation
- 1986-01-24 IE IE20586A patent/IE59629B1/en not_active IP Right Cessation
- 1986-01-24 IE IE930750A patent/IE930750L/xx unknown
- 1986-01-26 EG EG35/86A patent/EG17682A/xx active
- 1986-01-27 DE DE19863602347 patent/DE3602347A1/de not_active Ceased
- 1986-01-27 RO RO122011A patent/RO93483B/ro unknown
- 1986-01-27 NO NO860273A patent/NO170014C/no unknown
- 1986-01-27 DK DK39486A patent/DK39486A/da not_active Application Discontinuation
- 1986-01-27 SE SE8600355A patent/SE467824B/sv not_active IP Right Cessation
- 1986-01-27 CH CH2358/88A patent/CH670825A5/fr not_active IP Right Cessation
- 1986-01-27 PT PT81914A patent/PT81914B/pt not_active IP Right Cessation
- 1986-01-27 KR KR1019860000501A patent/KR900000675B1/ko not_active IP Right Cessation
- 1986-01-27 CH CH305/86A patent/CH667872A5/fr not_active IP Right Cessation
- 1986-01-27 ES ES551252A patent/ES8706112A1/es not_active Expired
- 1986-01-27 CH CH2357/88A patent/CH670824A5/fr not_active IP Right Cessation
- 1986-01-27 HU HU86375A patent/HU196367B/hu not_active IP Right Cessation
- 1986-01-28 DD DD86292943A patent/DD248584A5/de unknown
- 1986-01-28 PL PL25766886A patent/PL257668A1/xx unknown
- 1986-01-28 PL PL1986262317A patent/PL149156B1/pl unknown
- 1986-01-28 IT IT19206/86A patent/IT1190604B/it active
- 1986-01-28 GR GR860239A patent/GR860239B/el unknown
- 1986-01-28 PL PL1986262318A patent/PL262318A1/xx unknown
- 1986-01-28 DD DD86286545A patent/DD241600A5/de not_active IP Right Cessation
- 1986-01-28 CS CS86625A patent/CS253740B2/cs unknown
- 1986-01-28 AT AT0020386A patent/AT389511B/de not_active IP Right Cessation
- 1986-01-28 JP JP61017708A patent/JPH0780840B2/ja not_active Expired - Lifetime
- 1986-01-28 DD DD86292942A patent/DD248592A5/de unknown
- 1986-01-28 CN CN86100736A patent/CN1014894B/zh not_active Expired
- 1986-01-28 AR AR86302968A patent/AR242024A1/es active
- 1986-01-28 BE BE0/216191A patent/BE904121A/fr not_active IP Right Cessation
- 1986-09-09 ES ES557057A patent/ES8801917A1/es not_active Expired
- 1986-09-09 ES ES557056A patent/ES8800897A1/es not_active Expired
-
1987
- 1987-02-18 PH PH34872A patent/PH23093A/en unknown
- 1987-02-18 PH PH34871A patent/PH23084A/en unknown
- 1987-09-08 YU YU01670/87A patent/YU167087A/xx unknown
-
1988
- 1988-01-08 GB GB08800425A patent/GB2198133B/en not_active Expired
-
1989
- 1989-11-24 CA CA000615565A patent/CA1279322C/en not_active Expired - Lifetime
-
1990
- 1990-07-03 SE SE9002337A patent/SE502442C2/sv not_active IP Right Cessation
- 1990-07-03 SE SE9002338A patent/SE468896B/sv not_active IP Right Cessation
-
1995
- 1995-02-21 JP JP7032368A patent/JPH0853404A/ja active Pending
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