DD154608A5 - Verfahren zur herstellung von 1x oxo-1h-thiazolo-[3,2-a]pyrimidin-carboxamiden u.deren zwischenstufen - Google Patents
Verfahren zur herstellung von 1x oxo-1h-thiazolo-[3,2-a]pyrimidin-carboxamiden u.deren zwischenstufen Download PDFInfo
- Publication number
- DD154608A5 DD154608A5 DD80225391A DD22539180A DD154608A5 DD 154608 A5 DD154608 A5 DD 154608A5 DD 80225391 A DD80225391 A DD 80225391A DD 22539180 A DD22539180 A DD 22539180A DD 154608 A5 DD154608 A5 DD 154608A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- oxo
- pyrimidine
- ethyl
- compound
- mmol
- Prior art date
Links
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- 230000008569 process Effects 0.000 title claims abstract description 11
- 238000002360 preparation method Methods 0.000 title claims abstract description 6
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- 125000004432 carbon atom Chemical group C* 0.000 claims abstract description 19
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 14
- 125000002947 alkylene group Chemical group 0.000 claims abstract description 6
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- 238000010438 heat treatment Methods 0.000 claims description 29
- ULRPISSMEBPJLN-UHFFFAOYSA-N 2h-tetrazol-5-amine Chemical compound NC1=NN=NN1 ULRPISSMEBPJLN-UHFFFAOYSA-N 0.000 claims description 28
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- ZFCHNZDUMIOWFV-UHFFFAOYSA-N pyrimidine-2-carboxylic acid Chemical class OC(=O)C1=NC=CC=N1 ZFCHNZDUMIOWFV-UHFFFAOYSA-N 0.000 description 63
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9663179A | 1979-11-23 | 1979-11-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD154608A5 true DD154608A5 (de) | 1982-04-07 |
Family
ID=22258306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD80225391A DD154608A5 (de) | 1979-11-23 | 1980-11-21 | Verfahren zur herstellung von 1x oxo-1h-thiazolo-[3,2-a]pyrimidin-carboxamiden u.deren zwischenstufen |
Country Status (35)
| Country | Link |
|---|---|
| JP (1) | JPS5687586A (cs) |
| KR (1) | KR830004322A (cs) |
| AR (2) | AR228859A1 (cs) |
| AT (1) | AT380883B (cs) |
| AU (1) | AU520995B2 (cs) |
| BE (1) | BE886319A (cs) |
| CA (1) | CA1143731A (cs) |
| CH (1) | CH649299A5 (cs) |
| CS (1) | CS241476B2 (cs) |
| DD (1) | DD154608A5 (cs) |
| DE (2) | DE3050491C2 (cs) |
| DK (1) | DK151811C (cs) |
| EG (1) | EG14929A (cs) |
| ES (1) | ES497066A0 (cs) |
| FI (1) | FI67706C (cs) |
| FR (1) | FR2470132A1 (cs) |
| GB (1) | GB2063862B (cs) |
| GR (1) | GR72132B (cs) |
| GT (1) | GT198066458A (cs) |
| HU (1) | HU179091B (cs) |
| IE (1) | IE50404B1 (cs) |
| IL (1) | IL61535A (cs) |
| IN (1) | IN154926B (cs) |
| IT (1) | IT1209373B (cs) |
| LU (1) | LU82950A1 (cs) |
| NL (1) | NL182565C (cs) |
| NO (1) | NO803521L (cs) |
| NZ (1) | NZ195596A (cs) |
| PH (1) | PH16666A (cs) |
| PL (1) | PL132354B1 (cs) |
| PT (1) | PT72090B (cs) |
| SE (1) | SE448732B (cs) |
| SU (1) | SU1042620A3 (cs) |
| YU (1) | YU41953B (cs) |
| ZA (1) | ZA807293B (cs) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8300728D0 (en) * | 1983-01-12 | 1983-02-16 | Erba Farmitalia | Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives |
| US4457932A (en) * | 1983-07-22 | 1984-07-03 | Bristol-Myers Company | Anti-ulcer agents |
| GB8422916D0 (en) * | 1984-09-11 | 1984-10-17 | May & Baker Ltd | Compositions of matter |
| JP2690742B2 (ja) * | 1987-03-30 | 1997-12-17 | 第一製薬株式会社 | 複素環アミン誘導体 |
| DE68926473T2 (de) * | 1988-03-28 | 1996-10-02 | Janssen Pharmaceutica Nv | Mittel zur Konservierung oder Wiederherstellung der gesunden Haut |
| TWI500623B (zh) * | 2009-10-13 | 2015-09-21 | Torrent Pharmaceuticals Ltd | 新穎稠合噻唑及噁唑嘧啶酮 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1331059A (en) | 1971-04-19 | 1973-09-19 | Lilly Industries Ltd | Pyrimidotriazinone compounds |
| US4041163A (en) * | 1976-03-29 | 1977-08-09 | Pfizer Inc. | N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents |
| DE2810863A1 (de) * | 1978-03-13 | 1979-09-27 | Boehringer Mannheim Gmbh | 1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung |
| US4223031A (en) * | 1978-05-05 | 1980-09-16 | Mead Johnson & Company | Azolopyrimidinones |
-
1980
- 1980-09-30 DK DK413180A patent/DK151811C/da not_active IP Right Cessation
- 1980-10-15 IN IN760/DEL/80A patent/IN154926B/en unknown
- 1980-11-17 SU SU803212053A patent/SU1042620A3/ru active
- 1980-11-18 HU HU80802755A patent/HU179091B/hu not_active IP Right Cessation
- 1980-11-18 AR AR283276A patent/AR228859A1/es active
- 1980-11-18 GB GB8036904A patent/GB2063862B/en not_active Expired
- 1980-11-18 CS CS807820A patent/CS241476B2/cs unknown
- 1980-11-19 EG EG723/80A patent/EG14929A/xx active
- 1980-11-19 CH CH8567/80A patent/CH649299A5/fr not_active IP Right Cessation
- 1980-11-20 YU YU2950/80A patent/YU41953B/xx unknown
- 1980-11-20 GR GR63413A patent/GR72132B/el unknown
- 1980-11-20 NZ NZ195596A patent/NZ195596A/en unknown
- 1980-11-21 DE DE3050491A patent/DE3050491C2/de not_active Expired
- 1980-11-21 JP JP16450280A patent/JPS5687586A/ja active Granted
- 1980-11-21 NL NLAANVRAGE8006362,A patent/NL182565C/xx not_active IP Right Cessation
- 1980-11-21 DD DD80225391A patent/DD154608A5/de not_active IP Right Cessation
- 1980-11-21 ZA ZA00807293A patent/ZA807293B/xx unknown
- 1980-11-21 AU AU64595/80A patent/AU520995B2/en not_active Ceased
- 1980-11-21 NO NO803521A patent/NO803521L/no unknown
- 1980-11-21 IL IL61535A patent/IL61535A/xx unknown
- 1980-11-21 PT PT72090A patent/PT72090B/pt not_active IP Right Cessation
- 1980-11-21 CA CA000365258A patent/CA1143731A/en not_active Expired
- 1980-11-21 AT AT0570780A patent/AT380883B/de not_active IP Right Cessation
- 1980-11-21 LU LU82950A patent/LU82950A1/fr unknown
- 1980-11-21 ES ES497066A patent/ES497066A0/es active Granted
- 1980-11-21 SE SE8008189A patent/SE448732B/sv not_active IP Right Cessation
- 1980-11-21 FR FR8024822A patent/FR2470132A1/fr active Granted
- 1980-11-21 GT GT198066458A patent/GT198066458A/es unknown
- 1980-11-21 FI FI803628A patent/FI67706C/fi not_active IP Right Cessation
- 1980-11-21 IE IE2418/80A patent/IE50404B1/en unknown
- 1980-11-21 IT IT8026176A patent/IT1209373B/it active
- 1980-11-21 PH PH24891A patent/PH16666A/en unknown
- 1980-11-21 DE DE3043979A patent/DE3043979C2/de not_active Expired
- 1980-11-22 KR KR1019800004474A patent/KR830004322A/ko not_active Ceased
- 1980-11-22 PL PL1980228008A patent/PL132354B1/pl unknown
- 1980-11-24 BE BE0/202915A patent/BE886319A/fr not_active IP Right Cessation
-
1982
- 1982-09-13 AR AR290628A patent/AR231296A1/es active
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