DK413180A - Fremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolo (3,2-a)pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt mellemprodukter ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolo (3,2-a)pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt mellemprodukter ved fremgangsmaaden

Info

Publication number
DK413180A
DK413180A DK413180A DK413180A DK413180A DK 413180 A DK413180 A DK 413180A DK 413180 A DK413180 A DK 413180A DK 413180 A DK413180 A DK 413180A DK 413180 A DK413180 A DK 413180A
Authority
DK
Denmark
Prior art keywords
thiazolo
tetrazolyl
oxo
procedure
preparation
Prior art date
Application number
DK413180A
Other languages
English (en)
Other versions
DK151811B (da
DK151811C (da
Inventor
S B Kadin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK413180A publication Critical patent/DK413180A/da
Priority to DK13184A priority Critical patent/DK13184A/da
Publication of DK151811B publication Critical patent/DK151811B/da
Application granted granted Critical
Publication of DK151811C publication Critical patent/DK151811C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK413180A 1979-11-23 1980-09-30 Analogifremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolooe3,2-aaa-pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt 1-oxo-1h-thiazolooe3,2-aaapyrimidin-2-carboxylsyrer til anvendelse som udgangsmaterialer ved fremgangsmaaden DK151811C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK13184A DK13184A (da) 1979-11-23 1984-01-12 Analogifremgangsmaade til fremstilling af 1-oxo-1h-thiazolo(3,2-a)pyrimidin-2-carboxylsyrer eller farmaceutisk acceptable kationsalte deraf samt 1-oxo-1h-thiazolo(3,2-a)pyrimidin-2-carboxylsyreestere til anvendelse som mellemprodukter ved fremgangsmaaden

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9663179A 1979-11-23 1979-11-23
US9663179 1979-11-23

Publications (3)

Publication Number Publication Date
DK413180A true DK413180A (da) 1981-05-24
DK151811B DK151811B (da) 1988-01-04
DK151811C DK151811C (da) 1988-06-06

Family

ID=22258306

Family Applications (1)

Application Number Title Priority Date Filing Date
DK413180A DK151811C (da) 1979-11-23 1980-09-30 Analogifremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolooe3,2-aaa-pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt 1-oxo-1h-thiazolooe3,2-aaapyrimidin-2-carboxylsyrer til anvendelse som udgangsmaterialer ved fremgangsmaaden

Country Status (35)

Country Link
JP (1) JPS5687586A (da)
KR (1) KR830004322A (da)
AR (2) AR228859A1 (da)
AT (1) AT380883B (da)
AU (1) AU520995B2 (da)
BE (1) BE886319A (da)
CA (1) CA1143731A (da)
CH (1) CH649299A5 (da)
CS (1) CS241476B2 (da)
DD (1) DD154608A5 (da)
DE (2) DE3043979C2 (da)
DK (1) DK151811C (da)
EG (1) EG14929A (da)
ES (1) ES8203363A1 (da)
FI (1) FI67706C (da)
FR (1) FR2470132A1 (da)
GB (1) GB2063862B (da)
GR (1) GR72132B (da)
GT (1) GT198066458A (da)
HU (1) HU179091B (da)
IE (1) IE50404B1 (da)
IL (1) IL61535A (da)
IN (1) IN154926B (da)
IT (1) IT1209373B (da)
LU (1) LU82950A1 (da)
NL (1) NL182565C (da)
NO (1) NO803521L (da)
NZ (1) NZ195596A (da)
PH (1) PH16666A (da)
PL (1) PL132354B1 (da)
PT (1) PT72090B (da)
SE (1) SE448732B (da)
SU (1) SU1042620A3 (da)
YU (1) YU41953B (da)
ZA (1) ZA807293B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8300728D0 (en) * 1983-01-12 1983-02-16 Erba Farmitalia Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives
US4457932A (en) * 1983-07-22 1984-07-03 Bristol-Myers Company Anti-ulcer agents
GB8422916D0 (en) * 1984-09-11 1984-10-17 May & Baker Ltd Compositions of matter
JP2690742B2 (ja) * 1987-03-30 1997-12-17 第一製薬株式会社 複素環アミン誘導体
NZ228447A (en) * 1988-03-28 1990-08-28 Janssen Pharmaceutica Nv Cosmetic or pharmaceutical composition possessing serotonin antogonistic activity
TWI500623B (zh) * 2009-10-13 2015-09-21 Torrent Pharmaceuticals Ltd 新穎稠合噻唑及噁唑嘧啶酮

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1331059A (en) 1971-04-19 1973-09-19 Lilly Industries Ltd Pyrimidotriazinone compounds
US4041163A (en) * 1976-03-29 1977-08-09 Pfizer Inc. N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents
DE2810863A1 (de) * 1978-03-13 1979-09-27 Boehringer Mannheim Gmbh 1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones

Also Published As

Publication number Publication date
ATA570780A (de) 1985-12-15
CS782080A2 (en) 1985-06-13
NL8006362A (nl) 1981-06-16
HU179091B (en) 1982-08-28
ZA807293B (en) 1981-12-30
IN154926B (da) 1984-12-22
NL182565B (nl) 1987-11-02
FR2470132A1 (fr) 1981-05-29
IL61535A0 (en) 1980-12-31
IE50404B1 (en) 1986-04-16
CS241476B2 (en) 1986-03-13
DK151811B (da) 1988-01-04
GB2063862B (en) 1983-06-22
DE3043979C2 (de) 1986-08-21
AT380883B (de) 1986-07-25
NO803521L (no) 1981-05-25
IE802418L (en) 1981-05-23
ES497066A0 (es) 1982-04-01
KR830004322A (ko) 1983-07-09
PH16666A (en) 1983-12-13
JPS617432B2 (da) 1986-03-06
YU295080A (en) 1983-06-30
SE448732B (sv) 1987-03-16
AU6459580A (en) 1981-05-28
CH649299A5 (fr) 1985-05-15
PT72090B (en) 1981-09-29
AR228859A1 (es) 1983-04-29
PT72090A (en) 1980-12-01
FR2470132B1 (da) 1983-07-29
IT1209373B (it) 1989-07-16
FI67706C (fi) 1985-05-10
FI803628L (fi) 1981-05-24
PL132354B1 (en) 1985-02-28
LU82950A1 (fr) 1981-06-04
NZ195596A (en) 1984-05-31
BE886319A (fr) 1981-05-25
GB2063862A (en) 1981-06-10
DE3050491C2 (de) 1985-10-10
SU1042620A3 (ru) 1983-09-15
SE8008189L (sv) 1981-05-24
ES8203363A1 (es) 1982-04-01
EG14929A (en) 1989-01-30
PL228008A1 (da) 1981-12-11
IL61535A (en) 1984-06-29
DK151811C (da) 1988-06-06
GR72132B (da) 1983-09-19
IT8026176A0 (it) 1980-11-21
NL182565C (nl) 1988-04-05
AR231296A1 (es) 1984-10-31
AU520995B2 (en) 1982-03-11
GT198066458A (es) 1982-05-15
CA1143731A (en) 1983-03-29
JPS5687586A (en) 1981-07-16
DE3043979A1 (de) 1981-09-03
DD154608A5 (de) 1982-04-07
YU41953B (en) 1988-02-29
FI67706B (fi) 1985-01-31

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