CR10064A - Virus quimericos que presentan proteinas de superficie no nativas y usos de los mismos - Google Patents

Virus quimericos que presentan proteinas de superficie no nativas y usos de los mismos

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Publication number
CR10064A
CR10064A CR10064A CR10064A CR10064A CR 10064 A CR10064 A CR 10064A CR 10064 A CR10064 A CR 10064A CR 10064 A CR10064 A CR 10064A CR 10064 A CR10064 A CR 10064A
Authority
CR
Costa Rica
Prior art keywords
chemical
same
surface proteins
viruses
native surface
Prior art date
Application number
CR10064A
Other languages
English (en)
Inventor
Palese Peter
Garcia-Sastre Adolfo
Original Assignee
Nariko Ohara
Mount Sinai Medical Ct Of New York University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38092581&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR10064(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nariko Ohara, Mount Sinai Medical Ct Of New York University filed Critical Nariko Ohara
Publication of CR10064A publication Critical patent/CR10064A/es

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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
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    • A61K2039/552—Veterinary vaccine
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    • C07K2319/00—Fusion polypeptide
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16141—Use of virus, viral particle or viral elements as a vector
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    • C12N2760/16011—Orthomyxoviridae
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18141—Use of virus, viral particle or viral elements as a vector
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
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Abstract

La presente invención proporciona virus de RNA de cadena negativa quiméricos que permiten a un sujeto, por ejemplo, un ave, estar inmunizado contra dos agentes infecciosos mediante la utilización de un solo virus quimérico de la invención. En particular, la presente invención ofrece virus de influenza quiméricos manipulados para expresar e incorporar en sus viriones una proteína de fusión que comprende un ectodominio de una proteína de un agente infeccioso y el dominio de transmembrana y dominio citoplásmico de una proteína de virus de influenza.
CR10064A 2005-12-02 2008-06-11 Virus quimericos que presentan proteinas de superficie no nativas y usos de los mismos CR10064A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74183305P 2005-12-02 2005-12-02
US80286406P 2006-05-22 2006-05-22

Publications (1)

Publication Number Publication Date
CR10064A true CR10064A (es) 2008-09-08

Family

ID=38092581

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Application Number Title Priority Date Filing Date
CR10064A CR10064A (es) 2005-12-02 2008-06-11 Virus quimericos que presentan proteinas de superficie no nativas y usos de los mismos

Country Status (27)

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US (2) US9387242B2 (es)
EP (3) EP2251034B1 (es)
JP (1) JP5603012B2 (es)
KR (1) KR101492643B1 (es)
CN (1) CN101365479B (es)
AP (1) AP2911A (es)
AU (1) AU2006320490A1 (es)
CA (1) CA2631812C (es)
CL (1) CL2006003348A1 (es)
CR (1) CR10064A (es)
EA (1) EA016217B1 (es)
EC (1) ECSP088599A (es)
ES (2) ES2668464T3 (es)
GB (1) GB2447187C (es)
GE (1) GEP20135924B (es)
HK (1) HK1127731A1 (es)
HU (2) HUE037460T2 (es)
IL (1) IL191835A (es)
MX (1) MX2008007056A (es)
MY (1) MY147379A (es)
NO (1) NO20082743L (es)
NZ (1) NZ595736A (es)
PL (2) PL2251034T3 (es)
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