AR057225A1 - Vacunas marcadas contra el virus de la diarrea virica bovina - Google Patents

Vacunas marcadas contra el virus de la diarrea virica bovina

Info

Publication number
AR057225A1
AR057225A1 ARP060105386A ARP060105386A AR057225A1 AR 057225 A1 AR057225 A1 AR 057225A1 AR P060105386 A ARP060105386 A AR P060105386A AR P060105386 A ARP060105386 A AR P060105386A AR 057225 A1 AR057225 A1 AR 057225A1
Authority
AR
Argentina
Prior art keywords
virus
virica
bovina
vaccines
marked against
Prior art date
Application number
ARP060105386A
Other languages
English (en)
Inventor
Chichi Huang
Xuemei Cao
Michael G Sheppard
Gabriele Zybarth
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR057225A1 publication Critical patent/AR057225A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/18—Togaviridae; Flaviviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un virus de la diarrea vírica bovina que compende al menos una mutacion de aminoácido en el dominio helicasa en el que la mutacion en el dominio helicasa de NS3 produce una pérdida de reconocimiento por un anticuerpo monoclonal producido contra NS3 de tipo silvestre, pero en el que la replicacion de ARN viral y la generacion de virus infeccioso se mantiene. Se utiliza por ejemplo, para producir una vacuna marcada contra el virus de la diarrea vírica bovina o para diferenciar entre animales vacunados e infectados o no vacunados.
ARP060105386A 2005-12-07 2006-12-06 Vacunas marcadas contra el virus de la diarrea virica bovina AR057225A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74831205P 2005-12-07 2005-12-07

Publications (1)

Publication Number Publication Date
AR057225A1 true AR057225A1 (es) 2007-11-21

Family

ID=38123251

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060105386A AR057225A1 (es) 2005-12-07 2006-12-06 Vacunas marcadas contra el virus de la diarrea virica bovina

Country Status (17)

Country Link
US (2) US20080305130A1 (es)
EP (1) EP1973565B1 (es)
JP (1) JP2009519014A (es)
KR (2) KR101097547B1 (es)
CN (1) CN101355963B (es)
AR (1) AR057225A1 (es)
AU (1) AU2006323028B2 (es)
BR (1) BRPI0619566A2 (es)
CA (1) CA2639074C (es)
HK (1) HK1121698A1 (es)
NO (1) NO20081909L (es)
NZ (1) NZ567668A (es)
RU (1) RU2394594C2 (es)
TW (1) TW200734463A (es)
UA (1) UA95619C2 (es)
WO (1) WO2007066188A2 (es)
ZA (1) ZA200803558B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2130912A1 (en) 2008-06-04 2009-12-09 Institut für Viruskrankeiten und Immunprophylaxe Pestivirus replicons providing an RNA-based viral vector system
CN102517260A (zh) * 2011-12-29 2012-06-27 中国人民解放军军事医学科学院野战输血研究所 携带牛病毒性腹泻病毒非结构蛋白ns3优势区的融合蛋白及其重组表达方法与应用
MX2015002688A (es) * 2012-08-29 2015-05-12 Intervet Int Bv Vacuna indicadora.
US9480739B2 (en) * 2013-03-15 2016-11-01 Intervet Inc. Bovine virus vaccines that are liquid stable
CN103197082B (zh) * 2013-04-16 2015-07-15 深圳出入境检验检疫局动植物检验检疫技术中心 牛病毒性腹泻病毒抗体快速检测试纸条
EA025263B1 (ru) * 2014-06-23 2016-12-30 Общество С Ограниченной Ответственностью "Научно-Производственный Центр Пробиотех" Разбавитель-адъювант для сухой живой вакцины против трихофитии крупного рогатого скота
CN110554187B (zh) * 2018-05-30 2022-07-05 内蒙古元山生物科技有限公司 一种用于检测牛病毒性腹泻病毒抗体的表达蛋白、elisa试剂盒及其制备方法和应用
KR102434714B1 (ko) * 2021-02-16 2022-08-23 바디텍메드(주) 중화 항체 및 인터페론-감마 생성 여부를 이용한 능동 면역 진단을 위한 정보 제공 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593873A (en) 1986-01-27 1997-01-14 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5709865A (en) 1994-11-10 1998-01-20 Biostar Inc. Immunogenic composition against Bovine Viral Diarrhea Virus II glycoprotein 53 (BVDV-II gp53)
US6001613A (en) * 1996-05-24 1999-12-14 Board Of Regents Of University Of Nebraska Plasmid bearing a cDNA copy of the genome of bovine viral diarrhea virus, chimeric derivatives thereof, and method of producing an infectious bovine viral diarrhea virus using said plasmid
US6060457A (en) 1996-06-20 2000-05-09 Universite De Montreal DNA plasmid vaccine for immunization of animals against BVDV
US6168942B1 (en) * 1998-11-10 2001-01-02 Pfizer Inc. Attenuated forms of bovine viral diarrhea virus
JP4864661B2 (ja) * 2006-11-22 2012-02-01 東京エレクトロン株式会社 太陽電池の製造方法及び太陽電池の製造装置
KR20190058575A (ko) 2016-09-30 2019-05-29 광동 오포 모바일 텔레커뮤니케이션즈 코포레이션 리미티드 신호 전송 방법 및 장치

Also Published As

Publication number Publication date
KR20080065696A (ko) 2008-07-14
TW200734463A (en) 2007-09-16
AU2006323028B2 (en) 2010-02-25
US20120021001A1 (en) 2012-01-26
JP2009519014A (ja) 2009-05-14
KR20110045072A (ko) 2011-05-03
ZA200803558B (en) 2009-09-30
KR101097547B1 (ko) 2011-12-22
CN101355963A (zh) 2009-01-28
WO2007066188A3 (en) 2008-06-05
AU2006323028A1 (en) 2007-06-14
NZ567668A (en) 2011-07-29
BRPI0619566A2 (pt) 2011-10-04
EP1973565A2 (en) 2008-10-01
CA2639074A1 (en) 2007-06-14
HK1121698A1 (en) 2009-04-30
WO2007066188A2 (en) 2007-06-14
RU2394594C2 (ru) 2010-07-20
CN101355963B (zh) 2012-03-21
US20080305130A1 (en) 2008-12-11
EP1973565B1 (en) 2013-05-15
RU2008120331A (ru) 2010-01-20
UA95619C2 (ru) 2011-08-25
NO20081909L (no) 2008-05-21
KR101045165B1 (ko) 2011-06-30
CA2639074C (en) 2013-10-08

Similar Documents

Publication Publication Date Title
AR057225A1 (es) Vacunas marcadas contra el virus de la diarrea virica bovina
CY1118492T1 (el) Φαρμακοτεχνικες μορφες εμβολιου norovirus
CY1121215T1 (el) Αντιικα εμβολια με βελτιωμενη κυτταρικη ανοσογονικοτητα
ECSP088599A (es) Virus quiméricos que presentan proteínas de superficie no nativas y usos de los mismos
ATE513561T1 (de) Veränderung des th1/th2-gleichgewichts in spalt- grippeimpfstoffen mit adjuvantien
DE60121136D1 (de) Proteasom-influenzavirus-impfstoffzusammensetzung
WO2007024941A3 (en) Polyvalent vaccine
SI1951296T2 (sl) Iz celic izpeljana virusna cepiva z nizko stopnjo preostale celiäśne dna z obdelavo z betapropiolaktonom
EA200900784A1 (ru) Вакцины, включающие антиген из четырех штаммов вируса гриппа
MY163972A (en) Attenuated recombinant newcastle disease virus and vaccine containing the same
AR071220A1 (es) Astrovirus aviario depositado bajo el nuero cncm i-3895
CY1109036T1 (el) Εμβολιο περιλαμβανον εναν εξασθενημενο ιο πανωλης
ME01140B (me) Virus goveđe virusne dijareje s modifikovanim erns proteinom
EA201071086A1 (ru) Усовершенствованный способ получения вакцинных антигенов вируса гриппа
Van Hoeven et al. A novel synthetic TLR-4 agonist adjuvant increases the protective response to a clinical-stage West Nile virus vaccine antigen in multiple formulations
AR047581A1 (es) Vacunas de calicivirus felino
AR067439A1 (es) Virus quimericos antigenicos de virus de encefalitis de st. louis/virus dengue tipo 4
DK1578959T3 (da) Immunisering af fisk mod virusinfektion
ATE494377T1 (de) Vakzine gegen ipnv die aus hefezellen isoliert werden
AR041515A1 (es) Vacuna a dna contra el virus de papiloma humano
UY31574A1 (es) Vacunas contra la malaria
ECSP11010772A (es) Inhibidor de infección
NO20060395L (no) Antigenholdig dyrevaksine
MX2010007876A (es) Vectores virales recombinantes y composicion de vacuna para leishmaniasis.
CL2012001093A1 (es) Vacuna de adn basada en la region que codifica la envoltura del virus de la fiebre amarilla fusionada a lamp; y antigeno de vacuna.

Legal Events

Date Code Title Description
FA Abandonment or withdrawal