ATE513561T1 - Veränderung des th1/th2-gleichgewichts in spalt- grippeimpfstoffen mit adjuvantien - Google Patents
Veränderung des th1/th2-gleichgewichts in spalt- grippeimpfstoffen mit adjuvantienInfo
- Publication number
- ATE513561T1 ATE513561T1 AT06808431T AT06808431T ATE513561T1 AT E513561 T1 ATE513561 T1 AT E513561T1 AT 06808431 T AT06808431 T AT 06808431T AT 06808431 T AT06808431 T AT 06808431T AT E513561 T1 ATE513561 T1 AT E513561T1
- Authority
- AT
- Austria
- Prior art keywords
- adjuvants
- alteration
- clip
- balance
- flu vaccines
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73402605P | 2005-11-04 | 2005-11-04 | |
US81247506P | 2006-06-08 | 2006-06-08 | |
PCT/GB2006/004136 WO2007052059A2 (en) | 2005-11-04 | 2006-11-06 | Changing th1/th2 balance in split influenza vaccines with adjuvants |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE513561T1 true ATE513561T1 (de) | 2011-07-15 |
Family
ID=37897441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06808431T ATE513561T1 (de) | 2005-11-04 | 2006-11-06 | Veränderung des th1/th2-gleichgewichts in spalt- grippeimpfstoffen mit adjuvantien |
Country Status (12)
Country | Link |
---|---|
US (1) | US20090047353A1 (de) |
EP (1) | EP1951300B1 (de) |
JP (1) | JP5363107B2 (de) |
AT (1) | ATE513561T1 (de) |
AU (1) | AU2006310340B2 (de) |
CA (1) | CA2628397C (de) |
CY (1) | CY1112895T1 (de) |
DK (1) | DK1951300T3 (de) |
NZ (1) | NZ568212A (de) |
PL (1) | PL1951300T3 (de) |
PT (1) | PT1951300E (de) |
WO (1) | WO2007052059A2 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2420829T3 (es) * | 2005-11-04 | 2013-08-27 | Novartis Vaccines And Diagnostics S.R.L. | Vacunas adyuvantadas con antígeno de no virión preparadas a partir de virus de la gripe cultivados en cultivo celular |
EP2014279A1 (de) * | 2007-06-22 | 2009-01-14 | Pevion Biotech AG | Virosomen enthaltend Haemagglutinin, das von über Zelllinien hergestellten Influenza-Viren stammt, Zusammensetzungen, Herstellungsverfahren, Verwendung davon |
EP2268309B1 (de) | 2008-03-18 | 2015-01-21 | Novartis AG | Verbesserungen der herstellung von grippevirus-impstoff-antigenen |
DK2396032T3 (en) | 2009-02-10 | 2016-12-19 | Seqirus Uk Ltd | Influenza vaccines with reduced amounts of squalene |
EP2207031A1 (de) * | 2009-05-18 | 2010-07-14 | Abbott Biologicals B.V. | Hilfsstoffprüfung für Impfstoffzubereitungen |
PL2569267T5 (pl) | 2010-05-12 | 2017-10-31 | Novartis Ag | Ulepszone sposoby otrzymywania skwalenu |
MX2020004501A (es) | 2010-06-03 | 2021-11-09 | Pharmacyclics Llc | El uso de inhibidores de la tirosina quinasa de bruton (btk). |
GB201009273D0 (en) * | 2010-06-03 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel vaccine |
US9821051B1 (en) | 2010-10-28 | 2017-11-21 | Seqirus UK Limited | Reducing hospitalization in elderly influenza vaccine recipients |
BR112015001690A2 (pt) | 2012-07-24 | 2017-11-07 | Pharmacyclics Inc | mutações associadas com a resistência a inibidores da tirosina quinase de bruton (btk) |
WO2014071231A1 (en) | 2012-11-02 | 2014-05-08 | Pharmacyclics, Inc. | Tec family kinase inhibitor adjuvant therapy |
US9885086B2 (en) | 2014-03-20 | 2018-02-06 | Pharmacyclics Llc | Phospholipase C gamma 2 and resistance associated mutations |
WO2016001907A1 (en) * | 2014-07-02 | 2016-01-07 | Prendergast Patrick T | Mogroside iv and mogroside v as agonist/stimulator/un-blocking agent for toll-like receptor 4 and adjuvant for use in human/animal vaccine and to stimulate immunity against disease agents. |
US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1124013A (zh) * | 1993-02-19 | 1996-06-05 | 史密丝克莱恩比彻姆公司 | 含3-邻位-脱酰基的单磷酰基脂质a的流感疫苗组合物 |
ES2370937T3 (es) * | 1993-09-13 | 2011-12-23 | Protein Sciences Corporation | Un método para producir vacunas antigripales polivalentes a base de hemaglutinina. |
CN1285753A (zh) * | 1997-12-02 | 2001-02-28 | 鲍德杰克特疫苗公司 | 透皮给药微粒疫苗组合物 |
DE60020677T2 (de) * | 1999-02-26 | 2006-05-04 | Chiron Corp., Emeryville | Mikroemulsionen mit adsorbierten makromolekülen und mikropartikeln |
ES2228497T3 (es) * | 1999-04-19 | 2005-04-16 | Glaxosmithkline Biologicals S.A. | Composicion adyuvante que comprende saponina y un oligonucleotido inmunoestimulante. |
GB9923176D0 (en) | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
US20040109874A1 (en) * | 1999-11-10 | 2004-06-10 | Powderject Vaccines, Inc. | Induction of mucosal immunity by vaccination via the skin route |
JP2004508290A (ja) * | 2000-04-26 | 2004-03-18 | バイオベクター セラピューティクス | 免疫調節における粒状ベクターの使用 |
CA2406100C (en) * | 2000-04-28 | 2010-11-02 | St. Jude Children's Research Hospital | Dna transfection system for the generation of infectious influenza virus |
GB0025577D0 (en) * | 2000-10-18 | 2000-12-06 | Smithkline Beecham Biolog | Vaccine |
WO2004075829A2 (en) * | 2003-01-30 | 2004-09-10 | Chiron Corporation | Adjuvanted influenza vaccine |
US20070041998A1 (en) * | 2003-03-24 | 2007-02-22 | Intercell Ag | Use of alum and a th1 immune response inducing adjuvant for enhancing immune responses |
CA2565500A1 (en) * | 2004-05-28 | 2005-12-15 | Glaxosmithkline Biologicals S.A. | Vaccine compositions comprising virosomes and a saponin adjuvant |
WO2006060710A2 (en) * | 2004-12-02 | 2006-06-08 | Becton, Dickinson And Company | Vaccine formulations for intradermal delivery comprising adjuvants and antigenic agents |
EP1861122A1 (de) | 2005-03-23 | 2007-12-05 | GlaxoSmithKline Biologicals S.A. | Zusammensetzung |
-
2006
- 2006-11-06 US US12/092,146 patent/US20090047353A1/en not_active Abandoned
- 2006-11-06 DK DK06808431.8T patent/DK1951300T3/da active
- 2006-11-06 WO PCT/GB2006/004136 patent/WO2007052059A2/en active Application Filing
- 2006-11-06 JP JP2008538421A patent/JP5363107B2/ja active Active
- 2006-11-06 AU AU2006310340A patent/AU2006310340B2/en not_active Ceased
- 2006-11-06 AT AT06808431T patent/ATE513561T1/de active
- 2006-11-06 CA CA2628397A patent/CA2628397C/en not_active Expired - Fee Related
- 2006-11-06 NZ NZ568212A patent/NZ568212A/en not_active IP Right Cessation
- 2006-11-06 EP EP06808431A patent/EP1951300B1/de not_active Not-in-force
- 2006-11-06 PT PT06808431T patent/PT1951300E/pt unknown
- 2006-11-06 PL PL06808431T patent/PL1951300T3/pl unknown
-
2011
- 2011-09-15 CY CY20111100896T patent/CY1112895T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP5363107B2 (ja) | 2013-12-11 |
NZ568212A (en) | 2012-03-30 |
AU2006310340B2 (en) | 2011-02-10 |
EP1951300A2 (de) | 2008-08-06 |
JP2009514842A (ja) | 2009-04-09 |
EP1951300B1 (de) | 2011-06-22 |
PL1951300T3 (pl) | 2012-03-30 |
PT1951300E (pt) | 2011-09-05 |
AU2006310340A1 (en) | 2007-05-10 |
WO2007052059A2 (en) | 2007-05-10 |
CA2628397C (en) | 2013-08-20 |
WO2007052059A3 (en) | 2007-08-30 |
US20090047353A1 (en) | 2009-02-19 |
CA2628397A1 (en) | 2007-05-10 |
DK1951300T3 (da) | 2011-10-03 |
CY1112895T1 (el) | 2016-04-13 |
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