|
US3361306A
(en)
|
1966-03-31 |
1968-01-02 |
Merck & Co Inc |
Aerosol unit dispensing uniform amounts of a medically active ingredient
|
|
US3565070A
(en)
|
1969-02-28 |
1971-02-23 |
Riker Laboratories Inc |
Inhalation actuable aerosol dispenser
|
|
FR2224175B1
(es)
|
1973-04-04 |
1978-04-14 |
Isf Spa |
|
|
US4069819A
(en)
|
1973-04-13 |
1978-01-24 |
Societa Farmaceutici S.P.A. |
Inhalation device
|
|
IT1017153B
(it)
|
1974-07-15 |
1977-07-20 |
Isf Spa |
Apparecchio per inalazioni
|
|
SE438261B
(sv)
|
1981-07-08 |
1985-04-15 |
Draco Ab |
Anvendning i dosinhalator av ett perforerat membran
|
|
US4805811A
(en)
|
1985-03-29 |
1989-02-21 |
Aktiebolaget Draco |
Dosage device
|
|
SE448277B
(sv)
|
1985-04-12 |
1987-02-09 |
Draco Ab |
Indikeringsanordning vid en doseringsanordning for lekemedel
|
|
US4965288A
(en)
|
1988-02-25 |
1990-10-23 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5021456A
(en)
|
1988-02-25 |
1991-06-04 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5252608A
(en)
|
1988-02-25 |
1993-10-12 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5182297A
(en)
|
1988-02-25 |
1993-01-26 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US4943593A
(en)
|
1988-02-25 |
1990-07-24 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5059714A
(en)
|
1988-02-25 |
1991-10-22 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
US5120764A
(en)
|
1988-11-01 |
1992-06-09 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
|
IT1228459B
(it)
|
1989-02-23 |
1991-06-19 |
Phidea S R L |
Inalatore con svuotamento regolare e completo della capsula.
|
|
US4955371A
(en)
|
1989-05-08 |
1990-09-11 |
Transtech Scientific, Inc. |
Disposable inhalation activated, aerosol device for pulmonary medicine
|
|
US4997854A
(en)
|
1989-08-25 |
1991-03-05 |
Trustees Of Boston University |
Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates
|
|
US20030125519A1
(en)
|
1990-08-27 |
2003-07-03 |
Peter Besmer |
Ligand for the c-kit receptor and methods of use thereof
|
|
US6319494B1
(en)
|
1990-12-14 |
2001-11-20 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
|
DE4205148A1
(de)
|
1991-05-25 |
1993-01-21 |
Boehringer Mannheim Gmbh |
Monoklonale antikoerper gegen c-kit
|
|
KR100246082B1
(ko)
|
1991-07-02 |
2000-04-01 |
인헤일, 인코오포레이티드 |
에어로졸화된약제를전달하는방법및장치
|
|
IL104570A0
(en)
|
1992-03-18 |
1993-05-13 |
Yeda Res & Dev |
Chimeric genes and cells transformed therewith
|
|
US5261538A
(en)
|
1992-04-21 |
1993-11-16 |
Glaxo Inc. |
Aerosol testing method
|
|
US5785049A
(en)
|
1994-09-21 |
1998-07-28 |
Inhale Therapeutic Systems |
Method and apparatus for dispersion of dry powder medicaments
|
|
US5388572A
(en)
|
1993-10-26 |
1995-02-14 |
Tenax Corporation (A Connecticut Corp.) |
Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
|
|
US5522385A
(en)
|
1994-09-27 |
1996-06-04 |
Aradigm Corporation |
Dynamic particle size control for aerosolized drug delivery
|
|
US5874540A
(en)
|
1994-10-05 |
1999-02-23 |
Immunomedics, Inc. |
CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
|
|
US5622163A
(en)
|
1994-11-29 |
1997-04-22 |
Iep Group, Inc. |
Counter for fluid dispensers
|
|
US5544647A
(en)
|
1994-11-29 |
1996-08-13 |
Iep Group, Inc. |
Metered dose inhalator
|
|
WO1997027873A1
(en)
|
1996-01-30 |
1997-08-07 |
Brigham & Women's Hospital, Inc. |
Antibodies for modulating cd47-mediated neutrophil transmigration
|
|
CA2226962A1
(en)
|
1998-02-16 |
1999-08-16 |
Marie Sarfati |
Use of binding agents to cd47 and its ligands in the treatment or the prophylaxis of various inflammatory, autoimmune and allergic diseases and in the treatment of graft rejection
|
|
US6116234A
(en)
|
1999-02-01 |
2000-09-12 |
Iep Pharmaceutical Devices Inc. |
Metered dose inhaler agitator
|
|
EP1244707A1
(de)
|
1999-11-30 |
2002-10-02 |
Eberhard-Karls-Universität Tübingen Universitätsklinikum |
Antikörper gegen signal-regulator-proteine
|
|
AU7306201A
(en)
|
2000-06-30 |
2002-01-14 |
American Home Prod |
Substituted-triazolopyrimidines as anticancer agents
|
|
AU2002315052A1
(en)
|
2001-05-15 |
2002-11-25 |
Emory University |
Polynucleotides and polypeptides relating to the modulation of sirp alpha-cd47
|
|
FR2828206B1
(fr)
|
2001-08-03 |
2004-09-24 |
Centre Nat Rech Scient |
Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
|
|
US8435529B2
(en)
|
2002-06-14 |
2013-05-07 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
ATE417067T1
(de)
|
2002-03-01 |
2008-12-15 |
Immunomedics Inc |
Rs7 antikörper
|
|
JPWO2004080462A1
(ja)
|
2003-03-10 |
2006-06-08 |
エーザイ株式会社 |
ｃ−Ｋｉｔキナーゼ阻害剤
|
|
WO2005020921A2
(en)
|
2003-08-29 |
2005-03-10 |
Exelixis, Inc. |
C-kit modulators and methods of use
|
|
CA2545166A1
(en)
|
2003-11-11 |
2005-05-19 |
Chugai Seiyaku Kabushiki Kaisha |
Humanized anti-cd47 antibody
|
|
US8435539B2
(en)
|
2004-02-13 |
2013-05-07 |
Immunomedics, Inc. |
Delivery system for cytotoxic drugs by bispecific antibody pretargeting
|
|
SI3153514T1
(sl)
|
2004-05-13 |
2022-02-28 |
Icos Corporation |
Kinazolinoni kot zaviralci človeške fosfatidilinozitol 3-kinaze delta
|
|
DE602005011617D1
(de)
|
2004-05-19 |
2009-01-22 |
Medigene Ltd |
Hochaffiner ny-eso-t-zellen-rezeptor
|
|
CA2570817A1
(en)
|
2004-06-17 |
2006-01-26 |
Plexxikon, Inc. |
Azaindoles modulating c-kit activity and uses therefor
|
|
CA2591724C
(en)
|
2004-12-17 |
2014-08-05 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1h-phenantrho[9,10-d]imidazoles as mpges-1 inhibitors
|
|
US7442716B2
(en)
|
2004-12-17 |
2008-10-28 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors
|
|
US9707302B2
(en)
|
2013-07-23 |
2017-07-18 |
Immunomedics, Inc. |
Combining anti-HLA-DR or anti-Trop-2 antibodies with microtubule inhibitors, PARP inhibitors, bruton kinase inhibitors or phosphoinositide 3-kinase inhibitors significantly improves therapeutic outcome in cancer
|
|
JP5214252B2
(ja)
|
2005-03-03 |
2013-06-19 |
イミューノメディクス、インコーポレイテッド |
ヒト化ｌ２４３抗体
|
|
US20090142345A1
(en)
|
2005-03-15 |
2009-06-04 |
Takeda Pharmaceutical Company Limited |
Prophylactic/therapeutic agent for cancer
|
|
US20130039861A1
(en)
|
2005-04-06 |
2013-02-14 |
Immunomedics, Inc. |
Dye Conjugated Peptides for Fluorescent Imaging
|
|
EP1881981A1
(en)
|
2005-05-18 |
2008-01-30 |
Wyeth |
4, 6-diamino-[1,7] naphthyridine-3-carbonitrile inhibitors of tpl2 kinase and methods of making and using the same
|
|
WO2006124692A2
(en)
|
2005-05-18 |
2006-11-23 |
Wyeth |
3-cyanoquinoline inhibitors of tpl2 kinase and methods of making and using the same
|
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之８-經取代苯并氮雜呯
|
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體（ｔｏｌｌ-ｌｉｋｅ ｒｅｃｅｐｔｏｒ）調節劑之胺基二氮雜呯
|
|
WO2007032255A1
(ja)
|
2005-09-13 |
2007-03-22 |
Mie University |
Ｔ細胞レセプター及び該レセプターをコードする核酸
|
|
KR100788161B1
(ko)
|
2006-01-06 |
2007-12-21 |
(주)아모레퍼시픽 |
벤즈이미다졸 아민 유도체 또는 아미노퀴놀린 유도체를 함유하는 피부 미백용 조성물
|
|
TW200740776A
(en)
|
2006-02-06 |
2007-11-01 |
Osi Pharm Inc |
N-phenylbenzotriazolyl c-kit inhibitors
|
|
US7420040B2
(en)
|
2006-02-24 |
2008-09-02 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of TROP-2
|
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之ｃ-ｋｉｔ抗體
|
|
EP2019675A4
(en)
|
2006-05-02 |
2011-03-02 |
Merck Frosst Canada Ltd |
METHODS FOR TREATING OR PREVENTING NEOPLASIA
|
|
WO2007133811A2
(en)
|
2006-05-15 |
2007-11-22 |
Viral Logic Systems Technology Corp. |
Cd47 related compositions and methods for treating immunological diseases and disorders
|
|
IN2013MN00601A
(es)
|
2006-05-22 |
2015-06-12 |
Univ California |
|
|
ITMI20061053A1
(it)
|
2006-05-30 |
2007-11-30 |
Manuli Rubber Ind Spa |
Raccordo per tubi flessibili per applicazioni oleodinamiche,industriali e aria condizionata,avente caratteristiche di tenuta migliorate.
|
|
WO2008005877A2
(en)
|
2006-06-30 |
2008-01-10 |
Board Of Regents, The University Of Texas System |
Inhibitors of c-kit and uses thereof
|
|
DE102006058450A1
(de)
|
2006-12-12 |
2008-06-19 |
Eberhard-Karls-Universität Tübingen |
Zubereitungen zur Hemmung der Prostaglandin E2 Synthese
|
|
JP5395068B2
(ja)
|
2007-06-29 |
2014-01-22 |
ギリアード サイエンシーズ， インコーポレイテッド |
トール様受容体７の調節物質としてのプリン誘導体およびその使用
|
|
CN105330743B
(zh)
|
2007-08-02 |
2019-05-28 |
吉利德生物制剂公司 |
Lox和loxl2抑制剂及其应用
|
|
US20100239578A1
(en)
|
2007-10-11 |
2010-09-23 |
University Health Network |
Modulation of sirp-alpha - cd47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor
|
|
TW200930369A
(en)
|
2007-11-15 |
2009-07-16 |
Astrazeneca Ab |
Bis-(sulfonylamino) derivatives in therapy
|
|
TW200930368A
(en)
|
2007-11-15 |
2009-07-16 |
Astrazeneca Ab |
Bis-(sulfonylamino) derivatives in therapy
|
|
US20090163586A1
(en)
|
2007-12-20 |
2009-06-25 |
Astrazeneca Ab |
Bis-(Sulfonylamino) Derivatives in Therapy 205
|
|
US20100324086A1
(en)
|
2008-02-19 |
2010-12-23 |
Novasaid Ab |
Compounds and methods
|
|
WO2009117987A2
(de)
|
2008-03-26 |
2009-10-01 |
Universität Tübingen |
Verwendung von boswelliasäuren und synthetischen boswelliasäurederivaten zur hemmung der mikrosomalen prostaglandin e2 synthase und des cathepsin g
|
|
WO2009130242A1
(en)
|
2008-04-23 |
2009-10-29 |
Novasaid Ab |
Low molecular weight derivatives and use thereof in treatment of prostaglandin e synthase related diseases
|
|
EP2119705A1
(en)
|
2008-05-14 |
2009-11-18 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. |
3-Aminocarbozole compound, pharmaceutical composition containing it and preparation method therefor
|
|
DE102008027331A1
(de)
|
2008-06-07 |
2009-12-10 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Verwendung von Indol-3-carbonsäureestern zur Hemmung der mikrosomalen Prostaglandin E2 Synthase
|
|
DE102008015432A1
(de)
|
2008-06-12 |
2009-12-17 |
Eberhard-Karls-Universität Tübingen |
Verwendung von Pirinixinsäure-Derivaten zur Hemmung der Prostaglandin E2 Synthese
|
|
EP2313111B1
(en)
|
2008-08-01 |
2013-09-04 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
|
US8652843B2
(en)
|
2008-08-12 |
2014-02-18 |
Oncomed Pharmaceuticals, Inc. |
DDR1-binding agents and methods of use thereof
|
|
UY32138A
(es)
|
2008-09-25 |
2010-04-30 |
Boehringer Ingelheim Int |
Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables
|
|
US8450321B2
(en)
|
2008-12-08 |
2013-05-28 |
Gilead Connecticut, Inc. |
6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
|
|
RS53347B
(en)
|
2008-12-09 |
2014-10-31 |
Gilead Sciences, Inc. |
TOLL-SIMILAR RECEPTOR MODULATORS
|
|
EA201100947A1
(ru)
|
2008-12-19 |
2012-02-28 |
Новартис Аг |
Растворимые полипептиды, предназначенные для применения при лечении аутоиммунных и воспалительных нарушений
|
|
WO2010083253A2
(en)
|
2009-01-14 |
2010-07-22 |
Viral Logic Systems Technology Corp. |
Cd47 related compositions and methods for treating immunological diseases and disorders
|
|
TR201910848T4
(tr)
|
2009-02-13 |
2019-08-21 |
Immunomedics Inc |
İntraselüler olarak ayrilabi̇len bi̇r bağa sahi̇p i̇mmunokonjugatlar
|
|
UY32470A
(es)
|
2009-03-05 |
2010-10-29 |
Boehringer Ingelheim Int |
Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones
|
|
TWI491606B
(zh)
|
2009-07-13 |
2015-07-11 |
Gilead Sciences Inc |
調節細胞凋亡信號之激酶的抑制劑
|
|
DK2467377T3
(en)
|
2009-08-18 |
2017-04-03 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS
|
|
BR112012003703A2
(pt)
|
2009-08-18 |
2020-12-08 |
Ventrix Phramaceuticals, INC. |
Benzoazepinas substituídas como moduladores do receptor tipo toll
|
|
IN2012DN03112A
(es)
*
|
2009-09-11 |
2015-09-18 |
Cylene Pharamaceuticals Inc |
|
|
PT2491035T
(pt)
|
2009-10-22 |
2017-10-30 |
Gilead Sciences Inc |
Derivados de purina ou deazapurina úteis para o tratamento de (entre outros) infeções virais
|
|
EP2491007B1
(en)
|
2009-10-23 |
2013-09-25 |
Boehringer Ingelheim International GmbH |
Inhibitors of the microsomal prostaglandin E2 synthase-1
|
|
EP3018146A1
(en)
|
2009-11-18 |
2016-05-11 |
MannKind Corporation |
Monoclonal antibodies and diagnostic uses thereof
|
|
IN2012DN03354A
(es)
|
2009-12-02 |
2015-10-23 |
Immunomedics Inc |
|
|
JP2013514795A
(ja)
|
2009-12-22 |
2013-05-02 |
ノバルティス アーゲー |
治療における使用のための四価ｃｄ４７抗体定常領域融合タンパク質
|
|
SG181947A1
(en)
|
2009-12-30 |
2012-07-30 |
Arqule Inc |
Substituted imidazopyridinyl-aminopyridine compounds
|
|
CN105622757A
(zh)
|
2010-02-04 |
2016-06-01 |
吉联亚生物科技有限公司 |
结合赖氨酰氧化酶样2（loxl2）的抗体和其使用方法
|
|
EP2566479B1
(en)
|
2010-05-07 |
2014-12-24 |
GlaxoSmithKline LLC |
Azaindazoles
|
|
AU2011252851B2
(en)
|
2010-05-14 |
2016-10-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Humanized and chimeric monoclonal antibodies to CD47
|
|
WO2011146862A1
(en)
|
2010-05-21 |
2011-11-24 |
Bellicum Pharmaceuticals, Inc. |
Methods for inducing selective apoptosis
|
|
US8586604B2
(en)
|
2010-08-20 |
2013-11-19 |
Boehringer Ingelheim International Gmbh |
Inhibitors of the microsomal prostaglandin E2 synthase-1
|
|
US8759537B2
(en)
|
2010-08-20 |
2014-06-24 |
Boehringer Ingelheim International Gmbh |
3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
|
|
SG10201506703VA
(en)
|
2010-08-27 |
2015-10-29 |
Gilead Biologics Inc |
Antibodies To Matrix Metalloproteinase 9
|
|
JP6092107B2
(ja)
|
2010-10-01 |
2017-03-08 |
ベンティアールエックス ファーマシューティカルズ， インコーポレイテッドＶｅｎｔｉＲｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． |
アレルギー性疾患の治療方法
|
|
SG189071A1
(en)
|
2010-10-01 |
2013-05-31 |
Ventirx Pharmaceuticals Inc |
Therapeutic use of a tlr agonist and combination therapy
|
|
WO2012054825A1
(en)
|
2010-10-22 |
2012-04-26 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mage-a3 t cell receptors and related materials and methods of use
|
|
EA027153B1
(ru)
|
2010-12-09 |
2017-06-30 |
Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания |
Применение модифицированных t-клеток с химерными антигенными рецепторами для лечения злокачественных новообразований
|
|
UY33779A
(es)
|
2010-12-10 |
2012-07-31 |
Boehringer Ingelheim Int |
?2-(fenilamino)-1H-bencimidazol-5-carboxamidas novedosas?
|
|
US8466186B2
(en)
|
2010-12-10 |
2013-06-18 |
Boehringer Ingelheim International Gmbh |
Compounds
|
|
WO2012082647A2
(en)
|
2010-12-13 |
2012-06-21 |
The Regents Of The University Of California |
PYRAZOLE INHIBITORS OF COX-2 AND sEH
|
|
AR084174A1
(es)
|
2010-12-21 |
2013-04-24 |
Lilly Co Eli |
Compuestos de imidazol-2-benzamida utiles para el tratamiento de osteoartritis y una composicion farmaceutica
|
|
AU2012205486B2
(en)
|
2011-01-12 |
2017-02-02 |
Array Biopharma, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
|
DK2663555T3
(en)
|
2011-01-12 |
2017-03-27 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS
|
|
AU2012238564A1
(en)
|
2011-04-08 |
2013-09-26 |
Janssen Sciences Ireland Uc |
Pyrimidine derivatives for the treatment of viral infections
|
|
AR086044A1
(es)
|
2011-05-12 |
2013-11-13 |
Imclone Llc |
Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos
|
|
EA028254B1
(ru)
|
2011-05-18 |
2017-10-31 |
Янссен Сайенсиз Айрлэнд Юси |
Хиназолиновые производные для лечения вирусных инфекций и дальнейших заболеваний
|
|
AR086254A1
(es)
|
2011-05-26 |
2013-11-27 |
Lilly Co Eli |
Derivados de imidazol utiles para el tratamiento de artritis
|
|
WO2012170250A1
(en)
|
2011-06-07 |
2012-12-13 |
Radiation Control Technologies, Inc. |
Morpholino oligonucleotides capable of inhibiting cd47-mediated cellular damage and uses thereof
|
|
MY166866A
(en)
|
2011-08-18 |
2018-07-24 |
Nippon Shinyaku Co Ltd |
Heterocyclic derivative and pharmaceutical drug
|
|
US9550835B2
(en)
|
2011-08-23 |
2017-01-24 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-DDR1 antibody having anti-tumor activity
|
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
|
US20140378389A1
(en)
|
2011-09-15 |
2014-12-25 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
T cell receptors recognizing hla-a1- or hla-cw7-restricted mage
|
|
WO2013041865A1
(en)
|
2011-09-22 |
2013-03-28 |
Immunocore Limited |
T cell receptors
|
|
EP2763994A4
(en)
|
2011-10-04 |
2015-08-26 |
Gilead Calistoga Llc |
NEW QUINOXALINE INHIBITORS OF THE PI3K PATH
|
|
US20140242095A1
(en)
|
2011-10-19 |
2014-08-28 |
University Health Network |
Antibodies and antibody fragments targeting sirp-alpha and their use in treating hematologic cancers
|
|
CN104053672A
(zh)
|
2011-11-11 |
2014-09-17 |
瑞纳神经科学公司 |
Trop-2特异性抗体及其用途
|
|
WO2013072825A1
(en)
|
2011-11-16 |
2013-05-23 |
Glenmark Pharmaceuticals S.A. |
Phtalazinone derivatives as mpegs -1 inhibitors
|
|
US9427464B2
(en)
|
2011-11-22 |
2016-08-30 |
Chiome Bioscience Inc. |
Anti-human TROP-2 antibody having an antitumor activity in vivo
|
|
EA037918B1
(ru)
|
2011-12-21 |
2021-06-07 |
Новира Терапьютикс, Инк. |
Противовирусные агенты против гепатита в
|
|
JP6460796B2
(ja)
|
2012-01-17 |
2019-01-30 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
高親和性ｓｉｒｐ−アルファ試薬
|
|
UY34573A
(es)
|
2012-01-27 |
2013-06-28 |
Gilead Sciences Inc |
Inhibidor de la quinasa que regula la señal de la apoptosis
|
|
WO2013116562A1
(en)
|
2012-02-03 |
2013-08-08 |
Gilead Calistoga Llc |
Compositions and methods of treating a disease with (s)-4 amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile
|
|
PT2812443T
(pt)
|
2012-02-06 |
2019-09-05 |
Inhibrx Inc |
Anticorpos cd47 e métodos de utilização dos mesmos
|
|
JP6283320B2
(ja)
|
2012-02-08 |
2018-02-21 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染の治療のためのピペリジノ−ピリミジン誘導体
|
|
WO2013153535A1
(en)
|
2012-04-13 |
2013-10-17 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
|
TWI568722B
(zh)
|
2012-06-15 |
2017-02-01 |
葛蘭馬克製藥公司 |
作爲ｍＰＧＥＳ－１抑制劑之三唑酮化合物
|
|
MX369417B
(es)
|
2012-08-10 |
2019-11-07 |
Janssen Sciences Ireland Uc |
Derivados de alquilpirimidina para el tratamiento de infecciones víricas y otras enfermedades.
|
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
|
CN104981247A
(zh)
|
2012-09-06 |
2015-10-14 |
普莱希科公司 |
用于激酶调节的化合物和方法及其适应症
|
|
UY35044A
(es)
|
2012-09-24 |
2014-04-30 |
Gilead Sciences Inc |
ANTICUERPOS ANTI-dDr1
|
|
UA115677C2
(uk)
|
2012-10-10 |
2017-12-11 |
ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі |
ПОХІДНІ ПІРОЛО[3,2-d]ПІРИМІДИНУ ДЛЯ ЛІКУВАННЯ ВІРУСНИХ ІНФЕКЦІЙ ТА ІНШИХ ЗАХВОРЮВАНЬ
|
|
US20150297573A1
(en)
|
2012-10-24 |
2015-10-22 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING Beta-CELL SURVIVAL
|
|
NZ748345A
(en)
|
2012-11-16 |
2020-04-24 |
Janssen Sciences Ireland Uc |
Heterocyclic substituted 2-amino-quinazoline derivatives for the treatment of viral infections
|
|
ES2784631T3
(es)
|
2012-12-03 |
2020-09-29 |
Novimmune Sa |
Anticuerpos anti-CD47 y métodos de uso de los mismos
|
|
EP2931751B1
(en)
|
2012-12-12 |
2020-02-05 |
Arch Oncology, Inc. |
Therapeutic cd47 antibodies
|
|
US10413539B2
(en)
|
2012-12-13 |
2019-09-17 |
Immunomedics, Inc. |
Therapy for metastatic urothelial cancer with the antibody-drug conjugate, sacituzumab govitecan (IMMU-132)
|
|
US10744129B2
(en)
|
2012-12-13 |
2020-08-18 |
Immunomedics, Inc. |
Therapy of small-cell lung cancer (SCLC) with a topoisomerase-I inhibiting antibody-drug conjugate (ADC) targeting Trop-2
|
|
US9492566B2
(en)
|
2012-12-13 |
2016-11-15 |
Immunomedics, Inc. |
Antibody-drug conjugates and uses thereof
|
|
RU2666146C2
(ru)
|
2012-12-21 |
2018-09-06 |
Плексксикон Инк. |
Соединения и способы модулирования киназы и показания к их применению
|
|
AU2013364068B2
(en)
|
2012-12-21 |
2016-10-20 |
Gilead Calistoga Llc |
Substituted pyrimidine aminoalkyl-quinazolones as phosphatidylinositol 3-kinase inhibitors
|
|
ES2685568T3
(es)
|
2012-12-21 |
2018-10-10 |
Gilead Calistoga Llc |
Inhibidores de la isoquinolinona o quinazolinona fosfatidilinositol 3-quinasa
|
|
EP2951202B1
(en)
|
2013-01-29 |
2020-04-08 |
Max Delbrück Centrum für Molekulare Medizin (MDC) Berlin-Buch; |
High avidity binding molecules recognizing mage-a1
|
|
EP2958900B1
(en)
|
2013-02-21 |
2019-04-10 |
Janssen Sciences Ireland Unlimited Company |
2-aminopyrimidine derivatives for the treatment of viral infections
|
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
|
JP6361039B2
(ja)
|
2013-04-03 |
2018-07-25 |
アイビーシー ファーマスーティカルズ，インコーポレイテッド |
疾患に対する免疫反応を誘導するための併用療法
|
|
WO2014167444A1
(en)
|
2013-04-08 |
2014-10-16 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
|
US9221795B2
(en)
|
2013-06-14 |
2015-12-29 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|
|
GB201313377D0
(en)
|
2013-07-26 |
2013-09-11 |
Adaptimmune Ltd |
T cell receptors
|
|
WO2015059618A1
(en)
|
2013-10-22 |
2015-04-30 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS
|
|
US9290505B2
(en)
|
2013-12-23 |
2016-03-22 |
Gilead Sciences, Inc. |
Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
|
|
SG10201902571VA
(en)
|
2013-12-25 |
2019-04-29 |
Daiichi Sankyo Co Ltd |
Anti-trop2 antibody-drug conjugate
|
|
WO2015134536A1
(en)
|
2014-03-04 |
2015-09-11 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
EP3116544A4
(en)
|
2014-03-11 |
2017-08-23 |
The Board of Trustees of the Leland Stanford Junior University |
Anti sirp-alpha antibodies and bi-specific macrophage enhancing antibodies
|
|
BR112016021641A2
(pt)
|
2014-03-27 |
2017-08-15 |
Eicosis Llc |
Potentes inibidores da epóxido hidrolase solúveis
|
|
NZ725081A
(en)
|
2014-04-10 |
2018-02-23 |
Univ Washington |
Production of engineered t-cells by sleeping beauty transposon coupled with methotrexate selection
|
|
US10081629B2
(en)
|
2014-04-14 |
2018-09-25 |
Jiangsu Hengrui Medicine Co., Ltd. |
Amide derivatives and pharmaceutically acceptable salts thereof, preparation method thereof and medicinal application thereof
|
|
CA2957531A1
(en)
|
2014-08-08 |
2016-02-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Sirp alpha-antibody fusion proteins
|
|
TWI702228B
(zh)
|
2014-08-08 |
2020-08-21 |
美商Ａｌｘ腫瘤技術股份有限公司 |
信號調節蛋白α（ｓｉｇｎａｌ-ｒｅｇｕｌａｔｏｒｙ ｐｒｏｔｅｉｎ α， ＳＩＲＰ-α）變體構築物及其用途
|
|
AU2015303135B2
(en)
|
2014-08-15 |
2021-05-20 |
Merck Patent Gmbh |
SIRP-alpha immunoglobulin fusion proteins
|
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
|
JO3474B1
(ar)
|
2014-08-29 |
2020-07-05 |
Amgen Inc |
مشتقات تيتراهيدرونافثالين التي تثبط بروتين mcl-1
|
|
IL294043B1
(en)
|
2014-09-28 |
2024-06-01 |
Univ California |
Modulation of stimulatory and non-stimulatory myeloid cells
|
|
GB201417803D0
(en)
|
2014-10-08 |
2014-11-19 |
Adaptimmune Ltd |
T cell receptors
|
|
JO3581B1
(ar)
|
2014-10-29 |
2020-07-05 |
Lilly Co Eli |
مركبات ميثيل-بيبيريدين جديدة مفيدة لتثبيط إنزيم سينثاز -1 بروستاجلاندين e2 ميكروسومي
|
|
TW201627299A
(zh)
|
2014-10-29 |
2016-08-01 |
美國禮來大藥廠 |
用於抑制微粒體前列腺素ｅ合成酶１之新穎羧酸化合物
|
|
MX2017006485A
(es)
|
2014-11-18 |
2018-03-23 |
Janssen Pharmaceutica Nv |
Anticuerpos anti-cd47, metodos y usos.
|
|
CN107406508B
(zh)
|
2014-12-04 |
2022-04-05 |
地中海治疗诊断有限公司 |
人源化的抗trop-2单克隆抗体及其应用
|
|
US20160158360A1
(en)
|
2014-12-05 |
2016-06-09 |
Genentech, Inc. |
Methods and compositions for treating cancer using pd-1 axis antagonists and hpk1 antagonists
|
|
US20160166613A1
(en)
|
2014-12-15 |
2016-06-16 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlled elimination of therapeutic cells
|
|
KR102489471B1
(ko)
|
2014-12-30 |
2023-01-18 |
셀진 코포레이션 |
항-cd47 항체 및 그 용도
|
|
JP6643350B2
(ja)
|
2015-03-04 |
2020-02-12 |
ソレント・セラピューティクス・インコーポレイテッド |
Ｃｄ４７に結合する抗体医薬
|
|
WO2016142783A2
(en)
|
2015-03-10 |
2016-09-15 |
Leiden University Medical Center |
T-cell receptors directed against the preferentially expressed antigen of melanoma and uses thereof
|
|
CN107580499A
(zh)
|
2015-03-17 |
2018-01-12 |
欧姆尼奥克斯公司 |
通过蛋白质介导的o2递送调节肿瘤免疫性
|
|
US10358472B2
(en)
|
2015-05-06 |
2019-07-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
High affinity CD47 analogs
|
|
CN106188275A
(zh)
|
2015-05-06 |
2016-12-07 |
广州市香雪制药股份有限公司 |
识别ny-eso-1抗原短肽的t细胞受体
|
|
MX2017014188A
(es)
|
2015-05-07 |
2018-04-10 |
Agenus Inc |
Anticuerpos anti-ox40 y metodos para su uso.
|
|
CA2986713A1
(en)
|
2015-05-22 |
2016-12-01 |
Memorial Sloan-Kettering Cancer Center |
T cell receptor-like antibodies specific for a prame peptide
|
|
CN104804093A
(zh)
|
2015-05-27 |
2015-07-29 |
江苏春申堂药业有限公司 |
一种针对cd47的单域抗体
|
|
CA2986060A1
(en)
|
2015-05-29 |
2016-12-08 |
Valerie Odegard |
Composition and methods for regulating inhibitory interactions in genetically engineered cells
|
|
WO2016205042A1
(en)
|
2015-06-16 |
2016-12-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
SIRPα AGONIST ANTIBODY
|
|
EP3313873A4
(en)
|
2015-06-24 |
2019-04-24 |
Eureka Therapeutics, Inc. |
CONSTRUCTS TARGETING NY-ESO-1 / MHC PEPTIDE COMPLEXES AND USES THEREOF
|
|
US10195175B2
(en)
|
2015-06-25 |
2019-02-05 |
Immunomedics, Inc. |
Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
|
|
BR122023006150B1
(pt)
|
2015-06-25 |
2023-12-12 |
University Health Network |
Compostos inibidores de hpk1, seu uso, e composição farmacêutica que os compreende
|
|
JP6787890B2
(ja)
|
2015-06-29 |
2020-11-18 |
第一三共株式会社 |
抗体−薬物コンジュゲートの選択的製造方法
|
|
LT3331902T
(lt)
|
2015-08-07 |
2021-08-10 |
ALX Oncology Inc. |
Konstruktai, turintys sirp-alfa domeną arba jo variantą
|
|
EP3347374A1
(en)
|
2015-09-09 |
2018-07-18 |
Immune Design Corp. |
Ny-eso-1 specific tcrs and methods of use thereof
|
|
SG10202110257UA
(en)
|
2015-09-17 |
2021-10-28 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
RU2748401C2
(ru)
|
2015-09-18 |
2021-05-25 |
Арч Онколоджи, Инк. |
Терапевтические антитела к CD47
|
|
GB2558131B
(en)
|
2015-09-21 |
2021-05-19 |
Surface Oncology Inc |
Anti-CD47 antibodies and methods of use
|
|
MA43389A
(fr)
|
2015-12-02 |
2021-05-12 |
Agenus Inc |
Anticorps anti-ox40 et leurs procédés d'utilisation
|
|
SG11201804265XA
(en)
|
2015-12-02 |
2018-06-28 |
Agenus Inc |
Antibodies and methods of use thereof
|
|
WO2017096276A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
|
MA43387A
(fr)
|
2015-12-02 |
2018-10-10 |
Agenus Inc |
Anticorps anti-gitr et leurs méthodes d'utilisation
|
|
WO2017096182A1
(en)
|
2015-12-03 |
2017-06-08 |
Agenus Inc. |
Anti-ox40 antibodies and methods of use thereof
|
|
GB201522592D0
(en)
|
2015-12-22 |
2016-02-03 |
Immunocore Ltd |
T cell receptors
|
|
CA3177526A1
(en)
|
2016-01-11 |
2017-07-20 |
Forty Seven, Inc. |
Humanized, mouse or chimeric anti-cd47 monoclonal antibodies
|
|
CA3011372A1
(en)
|
2016-02-10 |
2017-08-17 |
Immunomedics, Inc. |
Combination of abcg2 inhibitors with sacituzumab govitecan (immu-132) overcomes resistance to sn-38 in trop-2 expressing cancers
|
|
WO2017147410A1
(en)
|
2016-02-25 |
2017-08-31 |
Amgen Inc. |
Compounds that inhibit mcl-1 protein
|
|
US10858338B2
(en)
|
2016-03-15 |
2020-12-08 |
The Regents Of The University Of California |
Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH)
|
|
CN107286077B
(zh)
|
2016-04-01 |
2021-04-02 |
合肥中科普瑞昇生物医药科技有限公司 |
一种选择性的c-kit激酶抑制剂
|
|
WO2017174822A1
(en)
|
2016-04-08 |
2017-10-12 |
Adaptimmune Limited |
T cell receptors
|
|
WO2017174823A1
(en)
|
2016-04-08 |
2017-10-12 |
Adaptimmune Limited |
T cell receptors
|
|
MX2018012269A
(es)
|
2016-04-08 |
2019-05-30 |
Adaptimmune Ltd |
Receptores de celulas t.
|
|
JP7254519B2
(ja)
|
2016-04-08 |
2023-04-10 |
イムノコア リミテッド |
Ｔ細胞レセプター
|
|
CN109071664B
(zh)
|
2016-04-14 |
2023-02-21 |
Ose免疫疗法 |
新型抗-SIRPa抗体及其治疗应用
|
|
DK3448882T3
(da)
|
2016-04-26 |
2022-02-21 |
Us Health |
Anti-kk-lc-1-t-cellereceptorer
|
|
WO2017196793A1
(en)
|
2016-05-09 |
2017-11-16 |
Celgene Corporation |
Cd47 antibodies and methods of use thereof
|
|
EP3243522A1
(en)
|
2016-05-10 |
2017-11-15 |
Université Pierre et Marie Curie (Paris 6) |
Agonist agents of cd47 inducing programmed cell death and their use in the treatments of diseases associated with defects in programmed cell death
|
|
CN114539273A
(zh)
|
2016-06-07 |
2022-05-27 |
北京加科思新药研发有限公司 |
可用作shp2抑制剂的新型杂环衍生物
|
|
CN106084052B
(zh)
|
2016-06-17 |
2019-12-27 |
长春金赛药业股份有限公司 |
抗cd47单克隆抗体及其应用
|
|
AU2017289158C1
(en)
|
2016-06-30 |
2020-07-23 |
Gilead Sciences, Inc. |
4,6-diaminoquinazolines as Cot modulators and methods of use thereof
|
|
KR20230142658A
(ko)
|
2016-08-03 |
2023-10-11 |
더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 |
항-SIRPalpha 항체 요법의 대식세포 증진 효능에서 Fc 수용체 참여의 붕괴
|
|
CN106297966A
(zh)
|
2016-08-22 |
2017-01-04 |
广东纳路纳米科技有限公司 |
一种金属纳米线‑抗氧化材料复合的透明导电膜及其制备
|
|
US10280164B2
(en)
|
2016-09-09 |
2019-05-07 |
Incyte Corporation |
Pyrazolopyridone compounds and uses thereof
|
|
WO2018049214A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
|
TW201811799A
(zh)
|
2016-09-09 |
2018-04-01 |
美商英塞特公司 |
吡唑并嘧啶化合物及其用途
|
|
CN115819417A
(zh)
|
2016-09-09 |
2023-03-21 |
因赛特公司 |
作为hpk1调节剂的吡唑并吡啶衍生物及其用于治疗癌症的用途
|
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
|
KR102423086B1
(ko)
|
2016-10-20 |
2022-07-20 |
아이-맵 바이오파마 유에스 리미티드 |
새로운 cd47 단일클론 항체 및 그 용도
|
|
EP3529276A4
(en)
|
2016-10-21 |
2020-06-17 |
Arch Oncology, Inc. |
CD47 THERAPEUTIC ANTIBODIES
|
|
US11352425B2
(en)
|
2016-11-08 |
2022-06-07 |
Absos, Llc |
Anti-CD47 antibodies
|
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
|
WO2018097951A1
(en)
|
2016-11-22 |
2018-05-31 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mage-a3/a6 antibodies
|
|
US10899768B2
(en)
|
2016-11-22 |
2021-01-26 |
Dana-Farber Cancer Institute, Inc. |
Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use
|
|
CN108779179B
(zh)
|
2016-11-28 |
2022-02-08 |
江苏恒瑞医药股份有限公司 |
Cd47抗体、其抗原结合片段及其医药用途
|
|
US11180482B2
(en)
|
2016-11-30 |
2021-11-23 |
Ariad Pharmaceuticals, Inc. |
Anilinopyrimidines as haematopoietic progenitor kinase 1 (HPK1) inhibitors
|
|
SG10201912879YA
(en)
|
2016-12-09 |
2020-02-27 |
Alector Llc |
Anti-sirp-alpha antibodies and methods of use thereof
|
|
CN116178343A
(zh)
|
2016-12-15 |
2023-05-30 |
阿瑞雅德制药公司 |
作为c-kit抑制剂的苯并咪唑化合物
|
|
IL312378A
(en)
|
2016-12-15 |
2024-06-01 |
Ariad Pharma Inc |
Aminothiazole compounds as C-KIT inhibitors
|
|
BR112019012878A2
(pt)
|
2016-12-23 |
2019-11-26 |
Arvinas Operations Inc |
compostos e métodos para a degradação alvo de polipeptídos de fibrossarcoma rapidamente acelerados
|
|
JP2020503883A
(ja)
|
2017-01-13 |
2020-02-06 |
アジェナス インコーポレイテッド |
Ｎｙ−ｅｓｏ−１に結合するｔ細胞受容体およびその使用方法
|
|
US11267885B2
(en)
|
2017-01-26 |
2022-03-08 |
Zlip Holding Limited |
CD47 antigen binding unit and uses thereof
|
|
CN110612294B
(zh)
|
2017-01-31 |
2024-01-16 |
阿尔维纳斯运营股份有限公司 |
人小脑蛋白配体和包含其的双官能化合物
|
|
WO2018167147A1
(en)
|
2017-03-15 |
2018-09-20 |
F. Hoffmann-La Roche Ag |
Azaindoles as inhibitors of hpk1
|
|
EP3595708A4
(en)
|
2017-03-15 |
2020-12-16 |
Fred Hutchinson Cancer Research Center |
HIGHLY POTENTIAL MAGE-A1 SPECIFIC TCRS AND USES
|
|
DE102017106305A1
(de)
|
2017-03-23 |
2018-09-27 |
Immatics Biotechnologies Gmbh |
Neue T-Zellrezeptoren und deren Verwendung in Immuntherapien gegen prame-positive Krebsarten
|
|
CA3057582C
(en)
|
2017-03-23 |
2024-01-09 |
Jacobio Pharmaceuticals Co., Ltd. |
Novel heterocyclic derivatives useful as shp2 inhibitors
|
|
WO2018183041A1
(en)
|
2017-03-27 |
2018-10-04 |
Immunomedics, Inc. |
Treatment of trop-2 expressing triple negative breast cancer with sacituzumab govitecan and a rad51 inhibitor
|
|
CN110709392B
(zh)
|
2017-03-30 |
2023-09-29 |
豪夫迈·罗氏有限公司 |
作为hpk1抑制剂的异喹啉
|
|
JP6453507B2
(ja)
|
2017-03-30 |
2019-01-16 |
アムジエン・インコーポレーテツド |
Ｍｃｌ−１タンパク質を阻害する化合物
|
|
JP7154221B2
(ja)
|
2017-03-30 |
2022-10-17 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｈｐｋ１の阻害剤としてのナフチリジン
|
|
EP3609922A2
(en)
|
2017-04-13 |
2020-02-19 |
Aduro Biotech Holdings, Europe B.V. |
Anti-sirp alpha antibodies
|
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
|
CA3063622A1
(en)
|
2017-05-16 |
2018-11-22 |
Synthon Biopharmaceuticals B.V. |
Anti-sirp.alpha. antibodies
|
|
WO2018217227A1
(en)
|
2017-05-24 |
2018-11-29 |
Immunomedics, Inc. |
Novel anti-pd-1 checkpoint inhibitor antibodies that block binding of pd-l1 to pd-1
|
|
WO2018223909A1
(zh)
|
2017-06-05 |
2018-12-13 |
成都海创药业有限公司 |
一种嵌合分子及其制备和应用
|
|
JP7202512B2
(ja)
|
2017-06-05 |
2023-01-12 |
国立大学法人三重大学 |
Ｍａｇｅ－ａ４由来ペプチドを認識する抗原結合性タンパク質
|
|
US20180353501A1
(en)
|
2017-06-09 |
2018-12-13 |
Arvinas, Inc. |
Modulators of proteolysis and associated methods of use
|
|
CN109096395B
(zh)
|
2017-06-20 |
2022-06-24 |
华兰生物工程股份有限公司 |
阻断型cd47纳米抗体及其用途
|
|
GB201709866D0
(en)
|
2017-06-20 |
2017-08-02 |
Immunocore Ltd |
T cell receptors
|
|
EP3641762A4
(en)
|
2017-06-20 |
2021-03-10 |
C4 Therapeutics, Inc. |
N / O BONDED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION
|
|
CN111448210B
(zh)
|
2017-07-26 |
2024-05-14 |
四十七公司 |
抗SIRP-α抗体及相关方法
|
|
US11401329B2
(en)
|
2017-08-02 |
2022-08-02 |
Phanes Therapeutics, Inc. |
Anti-CD47 antibodies and uses thereof
|
|
JP7267280B2
(ja)
|
2017-08-08 |
2023-05-01 |
パイオニア イミュノセラピューティクス インコーポレイテッド |
Ｔｒｅｍ１を発現する骨髄細胞を無能化させるための組成物および方法
|
|
CN107446050A
(zh)
|
2017-08-11 |
2017-12-08 |
百奥泰生物科技(广州)有限公司 |
Trop2阳性疾病治疗的化合物及方法
|
|
AU2018316742A1
(en)
|
2017-08-18 |
2020-03-19 |
Centessa Pharmaceuticals (Uk) Limited |
Binding agents
|
|
TWI793151B
(zh)
|
2017-08-23 |
2023-02-21 |
瑞士商諾華公司 |
3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
|
|
CN109422811A
(zh)
|
2017-08-29 |
2019-03-05 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
|
CN108503708B
(zh)
|
2017-09-01 |
2021-07-30 |
北京智仁美博生物科技有限公司 |
抗人cd47抗体及其用途
|
|
EP3679028A1
(en)
|
2017-09-04 |
2020-07-15 |
C4 Therapeutics, Inc. |
Dihydroquinolinones
|
|
WO2019043217A1
(en)
|
2017-09-04 |
2019-03-07 |
F. Hoffmann-La Roche Ag |
DIHYDROBENZIMIDAZOLONES
|
|
CN109422726B
(zh)
|
2017-09-04 |
2022-10-28 |
华东理工大学 |
CD47/SIRPα的阻断剂及其应用
|
|
WO2019067733A1
(en)
|
2017-09-27 |
2019-04-04 |
Vividion Therapeutics, Inc. |
COMPOUNDS AND METHODS FOR MODULATING PROTEIN DEGRADATION
|
|
WO2019079701A1
(en)
|
2017-10-20 |
2019-04-25 |
Dana-Farber Cancer Institute, Inc. |
HETEROBIFUNCTIONAL COMPOUNDS HAVING IMPROVED SPECIFICITY FOR BRD4 BROMODOMAINE
|
|
WO2019084030A1
(en)
|
2017-10-24 |
2019-05-02 |
Genentech, Inc. |
(4-HYDROXYPYRROLIDIN-2-YL) -HYDROXAMATE COMPOUNDS AND METHODS OF USE
|
|
EP3700901A1
(en)
|
2017-10-24 |
2020-09-02 |
Genentech, Inc. |
(4-hydroxypyrrolidin-2-yl)-heterocyclic compounds and methods of use thereof
|
|
WO2019084538A1
(en)
|
2017-10-27 |
2019-05-02 |
Board Of Regents, The University Of Texas System |
TUMOR SPECIFIC ANTIBODIES, T CELL RECEPTORS AND METHODS OF IDENTIFICATION THEREOF
|
|
CN111417653A
(zh)
|
2017-11-01 |
2020-07-14 |
蜂鸟生物科技控股私人有限公司 |
Cd47抗原结合分子
|
|
EP3710443A1
(en)
|
2017-11-17 |
2020-09-23 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 4 polypeptides
|
|
WO2019103203A1
(ko)
|
2017-11-24 |
2019-05-31 |
주식회사 젬백스앤카엘 |
신규 펩티드 및 이를 포함한 조성물
|
|
CA3083946A1
(en)
|
2017-12-01 |
2019-06-06 |
Seattle Genetics, Inc. |
Cd47 antibodies and uses thereof for treating cancer
|
|
CN109879957B
(zh)
|
2017-12-06 |
2022-03-18 |
香雪生命科学技术（广东）有限公司 |
针对prame的高亲和力t细胞受体
|
|
EP3723803A4
(en)
|
2017-12-12 |
2021-09-15 |
Pionyr Immunotherapeutics, Inc. |
ANTI-TREM2 ANTIBODIES AND RELATED METHODS
|
|
JP7438955B2
(ja)
|
2018-01-12 |
2024-02-27 |
オーリジーン オンコロジー リミテッド |
Ｃｄ４７シグナル伝達経路の阻害剤としての１，２，４－オキサジアゾール化合物
|
|
TW201932493A
(zh)
|
2018-01-24 |
2019-08-16 |
大陸商南京傳奇生物科技有限公司 |
不致顯著紅血球凝集的抗－ｃｄ４７抗體
|
|
GB201802201D0
(en)
|
2018-02-09 |
2018-03-28 |
Ultrahuman Five Ltd |
Binding agents
|
|
KR102445054B1
(ko)
|
2018-02-13 |
2022-09-22 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
CN110144009B
(zh)
|
2018-02-14 |
2020-01-21 |
上海洛启生物医药技术有限公司 |
Cd47单域抗体及其用途
|
|
US11267864B2
(en)
|
2018-02-26 |
2022-03-08 |
Medigene Immunotherapies Gmbh |
Nyeso tcr
|
|
TWI702954B
(zh)
|
2018-03-01 |
2020-09-01 |
美商美國禮來大藥廠 |
Cd73抑制劑
|
|
TWI823906B
(zh)
|
2018-03-09 |
2023-12-01 |
美商艾吉納斯公司 |
抗-cd73 抗體及其使用方法
|
|
US11884723B2
(en)
|
2018-03-13 |
2024-01-30 |
Ose Immunotherapeutics |
Use of anti-human SIRPa v1 antibodies and method for producing anti-SIRPa v1 antibodies
|
|
WO2019179366A1
(en)
|
2018-03-20 |
2019-09-26 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-cd47 antibodies
|
|
EP3768314A4
(en)
|
2018-03-21 |
2022-01-05 |
ALX Oncology Inc. |
ANTIBODIES AGAINST ALPHA SIGNAL REGULATING PROTEIN AND METHODS OF USE
|
|
GB201804860D0
(en)
|
2018-03-27 |
2018-05-09 |
Ultrahuman Two Ltd |
CD47 Binding agents
|
|
CN110305212A
(zh)
|
2018-03-27 |
2019-10-08 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
|
CN110386984B
(zh)
|
2018-04-17 |
2022-04-22 |
杭州尚健生物技术有限公司 |
结合cd47蛋白的融合蛋白及其应用
|
|
CN112236447B
(zh)
|
2018-04-19 |
2023-10-20 |
得克萨斯州大学系统董事会 |
具有mage-b2特异性的t细胞受体及其用途
|
|
CN110577597B
(zh)
|
2018-06-11 |
2021-10-22 |
康诺亚生物医药科技（成都）有限公司 |
一种阻断CD47和SIRPα相互作用的抗体
|
|
CN112566662A
(zh)
|
2018-06-15 |
2021-03-26 |
阿库鲁斯生物科学公司 |
针对cd47的阻断抗体及其使用方法
|
|
CN112601544A
(zh)
|
2018-07-05 |
2021-04-02 |
三钰生物科技股份有限公司 |
人类抗cd47抗体及其用途
|
|
CN114573699A
(zh)
|
2018-07-09 |
2022-06-03 |
启德医药科技（苏州）有限公司 |
滋养层细胞表面抗原2(trop2)特异性抗体
|
|
JP7368809B2
(ja)
|
2018-07-10 |
2023-10-25 |
国立大学法人神戸大学 |
抗ＳＩＲＰα抗体
|
|
LT3820573T
(lt)
|
2018-07-10 |
2023-11-10 |
Novartis Ag |
3-(5-hidroksi-1-oksoizoindolin-2-il)piperidin-2,6-diono dariniai ir jų naudojimas gydyti nuo ikaros šeimos cinko pirštų 2 (ikzf2) priklausomas ligas
|
|
US10774071B2
(en)
|
2018-07-13 |
2020-09-15 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
WO2020019135A1
(zh)
|
2018-07-23 |
2020-01-30 |
中国科学院微生物研究所 |
一种抗cd47抗体及其应用
|
|
EP3836960A4
(en)
|
2018-08-13 |
2022-05-11 |
Arch Oncology, Inc. |
THERAPEUTIC CD47 ANTIBODIES
|
|
JP2021535743A
(ja)
|
2018-08-31 |
2021-12-23 |
南京聖和薬業股▲ふん▼有限公司Nanjing Sanhome Pharmaceutical Co., Ltd. |
抗ｃｄ４７抗体及びその応用
|
|
EP3847265A4
(en)
|
2018-09-05 |
2023-02-15 |
The Regents of University of California |
COMPOSITION OF NY-ESO-1 SPECIFIC T LYMPHOCYTE RECEPTORS LIMITED ON MULTIPLE MOLECULES OF THE MAJOR HISTOCOMPATIBILITY COMPLEX
|
|
CN110950949B
(zh)
|
2018-09-26 |
2022-04-05 |
香雪生命科学技术（广东）有限公司 |
一种识别ssx2抗原的t细胞受体
|
|
BR112021005585A2
(pt)
|
2018-09-27 |
2021-06-29 |
Celgene Corporation |
proteínas de ligação a sirpa e métodos de uso das mesmas
|
|
KR20200040407A
(ko)
|
2018-10-10 |
2020-04-20 |
주식회사 노벨티노빌리티 |
신규 항-c-KIT 항체
|
|
EP3870602A1
(en)
|
2018-10-23 |
2021-09-01 |
Regeneron Pharmaceuticals, Inc. |
Ny-eso-1 t cell receptors and methods of use thereof
|
|
CN117105933A
(zh)
|
2018-10-31 |
2023-11-24 |
吉利德科学公司 |
具有hpk1抑制活性的取代的6-氮杂苯并咪唑化合物
|
|
HRP20240541T1
(hr)
|
2018-10-31 |
2024-07-05 |
Gilead Sciences, Inc. |
Supstituirani spojevi 6-azabenzimidazola kao inhibitori hpk1
|
|
WO2020094670A1
(en)
|
2018-11-05 |
2020-05-14 |
Synaffix B.V. |
Antibody-conjugates for targeting of tumours expressing trop-2
|
|
JP2022510313A
(ja)
|
2018-12-03 |
2022-01-26 |
ダナ－ファーバー キャンサー インスティテュート，インコーポレイテッド |
Ｈｅｌｉｏｓの低分子分解誘導剤および使用方法
|
|
SG11202106635WA
(en)
|
2018-12-21 |
2021-07-29 |
Daiichi Sankyo Co Ltd |
Combination of antibody-drug conjugate and kinase inhibitor
|
|
CA3124332A1
(en)
|
2018-12-27 |
2020-07-02 |
Shionogi & Co., Ltd. |
Novel anti-ccr8 antibody
|
|
KR20220015445A
(ko)
|
2019-05-29 |
2022-02-08 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 접합체의 투약
|
|
WO2020249063A1
(en)
|
2019-06-13 |
2020-12-17 |
Bio-Thera Solutions, Ltd. |
Methods for the treatment of trop2 positive diseases
|
|
US20220257632A1
(en)
|
2019-06-20 |
2022-08-18 |
Fred Hutchinson Cancer Research Center |
Microlumenal targeting of cancer cells
|
|
WO2020263830A1
(en)
|
2019-06-25 |
2020-12-30 |
Gilead Sciences, Inc. |
Flt3l-fc fusion proteins and methods of use
|
|
US20210093730A1
(en)
|
2019-10-01 |
2021-04-01 |
Immunomedics, Inc. |
Biomarkers for antibody-drug conjugate monotherapy or combination therapy
|
|
KR20220103753A
(ko)
|
2019-11-19 |
2022-07-22 |
브리스톨-마이어스 스큅 컴퍼니 |
헬리오스 단백질의 억제제로서 유용한 화합물
|
|
BR112022012625A2
(pt)
|
2019-12-24 |
2022-09-06 |
Carna Biosciences Inc |
Compostos moduladores de diacilglicerol quinase
|
|
CN117964757A
(zh)
|
2020-02-14 |
2024-05-03 |
吉利德科学公司 |
与ccr8结合的抗体和融合蛋白及其用途
|
|
CN111534585A
(zh)
|
2020-03-23 |
2020-08-14 |
至本医疗科技（上海）有限公司 |
一种非小细胞肺癌（nsclc）患者免疫疗法预后的方法
|
|
US20240043427A1
(en)
*
|
2020-05-01 |
2024-02-08 |
Gilead Sciences, Inc. |
Cd73 compounds
|
|
TW202216771A
(zh)
|
2020-06-26 |
2022-05-01 |
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