EA202092858A1 - ПРОИЗВОДНЫЕ ПИРРОЛО[1,2-b]ПИРИДАЗИНА - Google Patents

ПРОИЗВОДНЫЕ ПИРРОЛО[1,2-b]ПИРИДАЗИНА

Info

Publication number
EA202092858A1
EA202092858A1 EA202092858A EA202092858A EA202092858A1 EA 202092858 A1 EA202092858 A1 EA 202092858A1 EA 202092858 A EA202092858 A EA 202092858A EA 202092858 A EA202092858 A EA 202092858A EA 202092858 A1 EA202092858 A1 EA 202092858A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pyrrolo
pyridazine derivatives
compositions
compounds
compound
Prior art date
Application number
EA202092858A
Other languages
English (en)
Inventor
Стивен Амманн
Элизабет М. Бейкон
Гедиминас Брызгис
Элберт Чин
Чиньхун Чоу
Джероми Дж. Коттелл
Мэрилин Ндукве
Джеймс Г. Тэйлор
Натан И. Райт
Чжэн-Юй Ян
Шейла М. Зипфель
Original Assignee
Джилид Сайэнс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=67480334&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA202092858(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Джилид Сайэнс, Инк. filed Critical Джилид Сайэнс, Инк.
Publication of EA202092858A1 publication Critical patent/EA202092858A1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Соединение формулы (I)его фармацевтически приемлемые соли, его дейтерированные аналоги, их композиции и способы лечения заболеваний с применением соединений, при этом вариабельные заместители раскрыты в настоящем документе.
EA202092858A 2018-07-13 2019-07-11 ПРОИЗВОДНЫЕ ПИРРОЛО[1,2-b]ПИРИДАЗИНА EA202092858A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862697533P 2018-07-13 2018-07-13
PCT/US2019/041382 WO2020014468A1 (en) 2018-07-13 2019-07-11 Pyrrolo[1,2-b] pyridazine derivatives

Publications (1)

Publication Number Publication Date
EA202092858A1 true EA202092858A1 (ru) 2021-04-23

Family

ID=67480334

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202092858A EA202092858A1 (ru) 2018-07-13 2019-07-11 ПРОИЗВОДНЫЕ ПИРРОЛО[1,2-b]ПИРИДАЗИНА

Country Status (30)

Country Link
US (3) US10875866B2 (ru)
EP (2) EP3820872B1 (ru)
JP (2) JP7167298B2 (ru)
KR (2) KR20230144100A (ru)
CN (2) CN112513044B (ru)
AR (1) AR115731A1 (ru)
AU (3) AU2019302732B2 (ru)
BR (1) BR112020026675A2 (ru)
CA (1) CA3105485C (ru)
CL (1) CL2021000086A1 (ru)
CO (1) CO2021000153A2 (ru)
CR (1) CR20210014A (ru)
DK (1) DK3820872T3 (ru)
EA (1) EA202092858A1 (ru)
ES (1) ES2981798T3 (ru)
FI (1) FI3820872T3 (ru)
HR (1) HRP20240811T8 (ru)
IL (2) IL279654B2 (ru)
LT (1) LT3820872T (ru)
MX (1) MX2021000462A (ru)
NZ (1) NZ771681A (ru)
PE (1) PE20210404A1 (ru)
PH (1) PH12020552283A1 (ru)
PL (1) PL3820872T3 (ru)
PT (1) PT3820872T (ru)
SG (1) SG11202013003VA (ru)
TW (2) TWI721483B (ru)
UA (1) UA127506C2 (ru)
WO (1) WO2020014468A1 (ru)
ZA (1) ZA202100259B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI721483B (zh) * 2018-07-13 2021-03-11 美商基利科學股份有限公司 吡咯并[1,2-b]嗒𠯤衍生物
JP2023529877A (ja) * 2020-06-10 2023-07-12 シクソン エービー 結晶形のラベキシモドの調製方法
KR20240048010A (ko) 2021-08-18 2024-04-12 누릭스 테라퓨틱스 인코포레이티드 인터루킨-1 수용체 관련 키나제의 이작용성 분해제 및 이의 치료 용도

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