CN1990457A - 作为cxc－趋化因子受体配体的3,4－二取代的环丁烯－1,2－二酮 - Google Patents

作为cxc－趋化因子受体配体的3,4－二取代的环丁烯－1,2－二酮 Download PDF

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Publication number
CN1990457A
CN1990457A CNA2006101374093A CN200610137409A CN1990457A CN 1990457 A CN1990457 A CN 1990457A CN A2006101374093 A CNA2006101374093 A CN A2006101374093A CN 200610137409 A CN200610137409 A CN 200610137409A CN 1990457 A CN1990457 A CN 1990457A
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substituted
unsubstituted
compound
alkyl
formula
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CNA2006101374093A
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English (en)
Chinese (zh)
Inventor
A·G·塔维拉斯
C·J·阿基
R·W·邦德
巢健萍
M·德怀尔
J·A·费雷拉
曹建华
郁友农
J·J·巴尔德温
B·凯泽
李革
J·R·默里特
K·H·内尔森
L·L·罗科斯兹
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Pharmacopeia Drug Discovery Inc
Merck Sharp and Dohme LLC
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Pharmacopeia Drug Discovery Inc
Schering Corp
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Publication of CN1990457A publication Critical patent/CN1990457A/zh
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
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  • Dermatology (AREA)
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  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
CNA2006101374093A 2001-04-16 2002-04-15 作为cxc－趋化因子受体配体的3,4－二取代的环丁烯－1,2－二酮 Pending CN1990457A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28402601P 2001-04-16 2001-04-16
US60/284026 2001-04-16

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CNB028119797A Division CN1289471C (zh) 2001-04-16 2002-04-15 作为cxc－趋化因子受体配体的3,4－二取代的环丁烯－1,2－二酮

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CNA2006101374093A Pending CN1990457A (zh) 2001-04-16 2002-04-15 作为cxc－趋化因子受体配体的3,4－二取代的环丁烯－1,2－二酮

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103382192A (zh) * 2012-05-04 2013-11-06 同创医药(苏州)有限公司 N-单取代哌嗪衍生物的制备
CN110041309A (zh) * 2019-04-04 2019-07-23 广东工业大学 一种2-羧基哌嗪连接的他克林-8-氨基（羟基）喹啉衍生物及制备与应用

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US7132445B2 (en) 2001-04-16 2006-11-07 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
US20040106794A1 (en) 2001-04-16 2004-06-03 Schering Corporation 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
JP2005505595A (ja) 2001-10-12 2005-02-24 シェーリング　コーポレイション Ｃｘｃ−ケモカインレセプターアンタゴニストとしての３，４−二置換マレイミド化合物
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