CN103180326B - 杂环化合物及其用途 - Google Patents

杂环化合物及其用途 Download PDF

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Publication number
CN103180326B
CN103180326B CN201180048970.3A CN201180048970A CN103180326B CN 103180326 B CN103180326 B CN 103180326B CN 201180048970 A CN201180048970 A CN 201180048970A CN 103180326 B CN103180326 B CN 103180326B
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alkyl
group
halogen atom
optionally substituted
optionally
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CN103180326A (zh
Inventor
郡正城
今枝稔博
中村信二
丰福昌志
本多荣治
浅野恭臣
宇治川治
望月伦代
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Takeda Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CN201180048970.3A 2010-08-10 2011-08-09 杂环化合物及其用途 Active CN103180326B (zh)

Priority Applications (1)

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CN201510259936.0A CN104926837A (zh) 2010-08-10 2011-08-09 杂环化合物及其用途

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JP2010179577 2010-08-10
JP2010-179577 2010-08-10
PCT/JP2011/068497 WO2012020848A1 (en) 2010-08-10 2011-08-09 Heterocyclic compound and use thereof

Related Child Applications (1)

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CN103180326B true CN103180326B (zh) 2015-06-10

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US10875838B2 (en) 2017-03-21 2020-12-29 Fmc Corporation Pyrrolidinones and a process to prepare them
MX2019011090A (es) 2017-03-21 2019-11-18 Fmc Corp Mezcla herbicida, composición y método.
AR111839A1 (es) 2017-05-30 2019-08-21 Fmc Corp Lactamas 3-sustituidas herbicidas
AR111967A1 (es) 2017-05-30 2019-09-04 Fmc Corp Amidas herbicidas
EP3693368B1 (en) * 2017-10-06 2023-12-06 Takeda Pharmaceutical Company Limited Heterocyclic compound
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TWI504604B (zh) 2015-10-21
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AU2011290126A1 (en) 2013-03-07
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CN104926837A (zh) 2015-09-23
JP2013535408A (ja) 2013-09-12
US20130184266A1 (en) 2013-07-18
CO6680700A2 (es) 2013-05-31
CA2807460C (en) 2018-09-18
PT2603513T (pt) 2020-06-08
MA34509B1 (fr) 2013-09-02
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BR112013002250B1 (pt) 2020-10-27
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HRP20200844T1 (hr) 2020-08-21
US20130190291A1 (en) 2013-07-25
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US8575154B2 (en) 2013-11-05
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US20190263832A1 (en) 2019-08-29
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US8916551B2 (en) 2014-12-23
US20150073137A1 (en) 2015-03-12
AU2011290126B2 (en) 2016-01-07
ECSP13012478A (es) 2013-04-30
KR101852215B1 (ko) 2018-04-25
CN103180326A (zh) 2013-06-26
MX349470B (es) 2017-07-31
JP2016006080A (ja) 2016-01-14
SI2603513T1 (sl) 2020-07-31
UA111594C2 (uk) 2016-05-25
SG187656A1 (en) 2013-03-28
US20180162875A1 (en) 2018-06-14
US10654874B2 (en) 2020-05-19
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US9884875B2 (en) 2018-02-06
EA022078B1 (ru) 2015-10-30
EA201390222A1 (ru) 2013-08-30
US20200317692A1 (en) 2020-10-08
US20140080817A1 (en) 2014-03-20
WO2012020848A8 (en) 2012-09-27
KR20130138738A (ko) 2013-12-19
PE20131116A1 (es) 2013-10-24
US20120077799A1 (en) 2012-03-29
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JP6113789B2 (ja) 2017-04-12
MY165908A (en) 2018-05-18
GEP20156216B (en) 2015-01-12
PL2603513T3 (pl) 2020-07-27
US20240360156A1 (en) 2024-10-31
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US8778934B2 (en) 2014-07-15
BR112013002250A2 (pt) 2016-05-24
IL224452A (en) 2017-11-30
US20170022222A1 (en) 2017-01-26
EP2603513A1 (en) 2013-06-19
AR082618A1 (es) 2012-12-19
TW201217386A (en) 2012-05-01
US11279713B2 (en) 2022-03-22
US9499568B2 (en) 2016-11-22
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CA2807460A1 (en) 2012-02-16

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