CN102665715A - 治疗囊性纤维化和其他慢性疾病的组合物 - Google Patents
治疗囊性纤维化和其他慢性疾病的组合物 Download PDFInfo
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- CN102665715A CN102665715A CN2010800578878A CN201080057887A CN102665715A CN 102665715 A CN102665715 A CN 102665715A CN 2010800578878 A CN2010800578878 A CN 2010800578878A CN 201080057887 A CN201080057887 A CN 201080057887A CN 102665715 A CN102665715 A CN 102665715A
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- 0 CC*C(C)([C@]1(*C)*=CC)C1(C(Nc1c(*)cc2[n](*)c(C(C)(C)C*)cc2c1*)=O)c1cc(*)c(*)cc1 Chemical compound CC*C(C)([C@]1(*C)*=CC)C1(C(Nc1c(*)cc2[n](*)c(C(C)(C)C*)cc2c1*)=O)c1cc(*)c(*)cc1 0.000 description 4
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- Diabetes (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25418009P | 2009-10-22 | 2009-10-22 | |
| US61/254,180 | 2009-10-22 | ||
| PCT/US2010/053852 WO2011050325A1 (en) | 2009-10-22 | 2010-10-22 | Compositions for treatment of cystic fibrosis and other chronic diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102665715A true CN102665715A (zh) | 2012-09-12 |
Family
ID=43478427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010800578878A Pending CN102665715A (zh) | 2009-10-22 | 2010-10-22 | 治疗囊性纤维化和其他慢性疾病的组合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20110098311A1 (enExample) |
| EP (2) | EP2490687A1 (enExample) |
| JP (1) | JP2013508414A (enExample) |
| CN (1) | CN102665715A (enExample) |
| AU (1) | AU2010310449A1 (enExample) |
| CA (1) | CA2777245A1 (enExample) |
| MX (1) | MX2012004792A (enExample) |
| WO (1) | WO2011050325A1 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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- 2010-10-22 AU AU2010310449A patent/AU2010310449A1/en not_active Abandoned
- 2010-10-22 EP EP10773489A patent/EP2490687A1/en not_active Withdrawn
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104030981A (zh) * | 2013-03-06 | 2014-09-10 | 上海特化医药科技有限公司 | Ivacaftor的制备方法及其中间体 |
| WO2014135096A1 (zh) * | 2013-03-06 | 2014-09-12 | 上海特化医药科技有限公司 | Ivacaftor 的制备方法及其中间体 |
| CN105130949A (zh) * | 2015-09-02 | 2015-12-09 | 阜新奥瑞凯新材料有限公司 | 1-(2,2-二氟苯并[d][1,3]二氧杂环戊烯-5-基)环丙基腈的制备方法 |
| CN106478606A (zh) * | 2016-09-21 | 2017-03-08 | 沈阳药科大学 | N‑取代吲哚类衍生物及其应用 |
| CN106478606B (zh) * | 2016-09-21 | 2019-05-10 | 沈阳药科大学 | N-取代吲哚类衍生物及其应用 |
| CN107982260A (zh) * | 2017-12-12 | 2018-05-04 | 南京市儿童医院 | VX-809在制备治疗Bartter综合征药物中的应用 |
| CN111187197A (zh) * | 2020-01-13 | 2020-05-22 | 苏州旺山旺水生物医药有限公司 | 一种Tezacaftor中间体的合成方法 |
| CN111187197B (zh) * | 2020-01-13 | 2021-10-01 | 苏州旺山旺水生物医药有限公司 | 一种Tezacaftor中间体的合成方法 |
| CN113880735A (zh) * | 2021-11-08 | 2022-01-04 | 湖北九宁化学科技有限公司 | 一种双氟磺酰二乙胺锂的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20150150879A2 (en) | 2015-06-04 |
| AU2010310449A1 (en) | 2012-05-03 |
| WO2011050325A1 (en) | 2011-04-28 |
| EP2490687A1 (en) | 2012-08-29 |
| US20140121208A1 (en) | 2014-05-01 |
| US20110098311A1 (en) | 2011-04-28 |
| MX2012004792A (es) | 2013-02-01 |
| US20140329814A2 (en) | 2014-11-06 |
| JP2013508414A (ja) | 2013-03-07 |
| EP2813227A1 (en) | 2014-12-17 |
| CA2777245A1 (en) | 2011-04-28 |
| US20150231142A1 (en) | 2015-08-20 |
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