HK1220610A1 - 噠嗪酮化合物和用於治療囊腫狀纖維化的方法 - Google Patents
噠嗪酮化合物和用於治療囊腫狀纖維化的方法Info
- Publication number
- HK1220610A1 HK1220610A1 HK16108633.8A HK16108633A HK1220610A1 HK 1220610 A1 HK1220610 A1 HK 1220610A1 HK 16108633 A HK16108633 A HK 16108633A HK 1220610 A1 HK1220610 A1 HK 1220610A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatment
- methods
- cystic fibrosis
- pyridazinone compounds
- pyridazinone
- Prior art date
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- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361778870P | 2013-03-13 | 2013-03-13 | |
PCT/US2014/026623 WO2014160440A1 (en) | 2013-03-13 | 2014-03-13 | Pyridazinone compounds and methods for the treatment of cystic fibrosis |
Publications (1)
Publication Number | Publication Date |
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HK1220610A1 true HK1220610A1 (zh) | 2017-05-12 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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HK16108633.8A HK1220610A1 (zh) | 2013-03-13 | 2016-07-20 | 噠嗪酮化合物和用於治療囊腫狀纖維化的方法 |
Country Status (12)
Country | Link |
---|---|
US (8) | US8937178B2 (zh) |
EP (1) | EP2968323A4 (zh) |
JP (1) | JP6545148B2 (zh) |
KR (1) | KR101943490B1 (zh) |
CN (1) | CN105307655B (zh) |
AU (1) | AU2014243818B2 (zh) |
BR (1) | BR112015023328A2 (zh) |
CA (2) | CA3044766A1 (zh) |
HK (1) | HK1220610A1 (zh) |
MX (1) | MX365950B (zh) |
NZ (1) | NZ712180A (zh) |
WO (1) | WO2014160440A1 (zh) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE049976T2 (hu) | 2005-12-28 | 2020-11-30 | Vertex Pharma | N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid amorf alakjának gyógyászati kompozíciói |
US8937178B2 (en) * | 2013-03-13 | 2015-01-20 | Flatley Discovery Lab | Phthalazinone compounds and methods for the treatment of cystic fibrosis |
CA2952862A1 (en) | 2014-06-19 | 2015-12-23 | Proteostasis Therapeutics, Inc. | Compounds, compositions and methods of increasing cftr activity |
WO2016023877A1 (en) | 2014-08-14 | 2016-02-18 | F. Hoffmann-La Roche Ag | Novel pyridazones and triazinones for the treatment and prophylaxis of hepatitis b virus infection |
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KR20170063954A (ko) | 2014-10-07 | 2017-06-08 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 막횡단 전도도 조절자의 조정제의 공-결정 |
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2014
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- 2014-03-13 KR KR1020157027647A patent/KR101943490B1/ko active IP Right Grant
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- 2014-03-13 EP EP14773937.9A patent/EP2968323A4/en not_active Withdrawn
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- 2014-03-13 BR BR112015023328A patent/BR112015023328A2/pt not_active Application Discontinuation
- 2014-03-13 CN CN201480021457.9A patent/CN105307655B/zh not_active Expired - Fee Related
- 2014-03-13 WO PCT/US2014/026623 patent/WO2014160440A1/en active Application Filing
- 2014-03-13 MX MX2015012866A patent/MX365950B/es active IP Right Grant
- 2014-03-13 AU AU2014243818A patent/AU2014243818B2/en not_active Ceased
-
2015
- 2015-01-19 US US14/599,998 patent/US9682969B2/en active Active
-
2016
- 2016-07-20 HK HK16108633.8A patent/HK1220610A1/zh unknown
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2017
- 2017-06-06 US US15/615,466 patent/US10280160B2/en active Active
- 2017-10-06 US US15/726,813 patent/US10370366B2/en active Active
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2019
- 2019-04-30 US US16/398,680 patent/US10889576B2/en active Active
- 2019-07-15 US US16/511,315 patent/US20200017486A1/en not_active Abandoned
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