CN102264903A - 有效跳跃人杜兴肌营养不良前mRNA外显子45的方法和手段 - Google Patents
有效跳跃人杜兴肌营养不良前mRNA外显子45的方法和手段 Download PDFInfo
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Abstract
Description
Claims (15)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07119351 | 2007-10-26 | ||
NLPCT/NL2008/050673 | 2008-10-27 | ||
PCT/NL2008/050673 WO2009054725A2 (en) | 2007-10-26 | 2008-10-27 | Means and methods for counteracting muscle disorders |
PCT/NL2009/050006 WO2010050801A1 (en) | 2008-10-27 | 2009-01-13 | Methods and means for efficient skipping of exon 45 in duchenne muscular dystrophy pre-mrna |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102264903A true CN102264903A (zh) | 2011-11-30 |
CN102264903B CN102264903B (zh) | 2015-01-07 |
Family
ID=39045623
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610053552.8A Active CN105641700B (zh) | 2007-10-26 | 2008-10-27 | 对抗肌肉病症的方式和方法 |
CN200880120198XA Pending CN101896186A (zh) | 2007-10-26 | 2008-10-27 | 对抗肌肉病症的方式和方法 |
CN200980152464.1A Active CN102264903B (zh) | 2007-10-26 | 2009-01-13 | 有效跳跃人杜兴肌营养不良前mRNA外显子45的方法和手段 |
CN2009801519198A Pending CN102256606A (zh) | 2007-10-26 | 2009-03-11 | 有效跳跃人杜兴肌营养不良基因外显子43、46、50-53中至少一个的方法和手段 |
CN201510825064.XA Pending CN105647921A (zh) | 2007-10-26 | 2009-03-11 | 有效跳跃人杜兴肌营养不良基因外显子43、46、50-53中至少一个的方法和手段 |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610053552.8A Active CN105641700B (zh) | 2007-10-26 | 2008-10-27 | 对抗肌肉病症的方式和方法 |
CN200880120198XA Pending CN101896186A (zh) | 2007-10-26 | 2008-10-27 | 对抗肌肉病症的方式和方法 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009801519198A Pending CN102256606A (zh) | 2007-10-26 | 2009-03-11 | 有效跳跃人杜兴肌营养不良基因外显子43、46、50-53中至少一个的方法和手段 |
CN201510825064.XA Pending CN105647921A (zh) | 2007-10-26 | 2009-03-11 | 有效跳跃人杜兴肌营养不良基因外显子43、46、50-53中至少一个的方法和手段 |
Country Status (17)
Country | Link |
---|---|
US (18) | US9243245B2 (zh) |
EP (4) | EP2203173B1 (zh) |
JP (6) | JP5600064B2 (zh) |
CN (5) | CN105641700B (zh) |
AU (1) | AU2008317566B2 (zh) |
CA (1) | CA2704049A1 (zh) |
CY (2) | CY1117286T1 (zh) |
DK (1) | DK2203173T3 (zh) |
ES (5) | ES2564563T3 (zh) |
HK (2) | HK1185098A1 (zh) |
HR (1) | HRP20160025T1 (zh) |
HU (2) | HUE028662T2 (zh) |
IL (4) | IL205322A (zh) |
NZ (2) | NZ584793A (zh) |
PL (1) | PL2203173T3 (zh) |
PT (1) | PT2203173E (zh) |
WO (1) | WO2009054725A2 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110257379A (zh) * | 2012-07-03 | 2019-09-20 | 马林生物科技有限公司 | 用于治疗肌肉萎缩症患者的寡核苷酸 |
Families Citing this family (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1191097A1 (en) * | 2000-09-21 | 2002-03-27 | Leids Universitair Medisch Centrum | Induction of exon skipping in eukaryotic cells |
CA2524255C (en) | 2003-03-21 | 2014-02-11 | Academisch Ziekenhuis Leiden | Modulation of exon recognition in pre-mrna by interfering with the secondary rna structure |
HUE059464T2 (hu) | 2003-04-11 | 2022-11-28 | Ptc Therapeutics Inc | 1,2,4-Oxadiazolbenzoesav-vegyületek és ezek alkalmazása nonsense szuppresszióhoz és betegségek kezelésére |
EP4272748A3 (en) | 2004-06-28 | 2024-03-27 | The University Of Western Australia | Antisense oligonucleotides for inducing exon skipping and methods of use thereof |
USRE48960E1 (en) | 2004-06-28 | 2022-03-08 | The University Of Western Australia | Antisense oligonucleotides for inducing exon skipping and methods of use thereof |
CA2596506C (en) | 2005-02-09 | 2021-04-06 | Avi Biopharma, Inc. | Antisense composition and method for treating muscle atrophy |
DK2049664T3 (da) | 2006-08-11 | 2012-01-02 | Prosensa Technologies Bv | Enkeltstrengede oligonukleotider, som er komplementære til repetitive elementer, til behandling af med DNA-repetitiv-ustabilitet associerede lidelser |
EP2203173B1 (en) | 2007-10-26 | 2015-12-23 | Academisch Ziekenhuis Leiden | Means and methods for counteracting muscle disorders |
EP2119783A1 (en) | 2008-05-14 | 2009-11-18 | Prosensa Technologies B.V. | Method for efficient exon (44) skipping in Duchenne Muscular Dystrophy and associated means |
US8084601B2 (en) | 2008-09-11 | 2011-12-27 | Royal Holloway And Bedford New College Royal Holloway, University Of London | Oligomers |
JP5864257B2 (ja) | 2008-10-24 | 2016-02-17 | サレプタ セラピューティクス, インコーポレイテッド | Dmdのための複数のエキソンスキッピング組成物 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110257379A (zh) * | 2012-07-03 | 2019-09-20 | 马林生物科技有限公司 | 用于治疗肌肉萎缩症患者的寡核苷酸 |
CN110257379B (zh) * | 2012-07-03 | 2023-08-11 | 马林生物科技有限公司 | 用于治疗肌肉萎缩症患者的寡核苷酸 |
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