CL2013001252A1 - Capsula para administracion oral que comprende n-terc-butil-3-[(5-metil-2-{[4-(2-pirrolidin-1-iletoxi)fenil]amino}pirimidin-4-il)amino]bencenosulfonamida, una celulosa microcristalina y estearil fumarato de sodio; forma de dosificacion unitaria; metodo para tratar mielofibrosis; metodo de preparacion; y articulo de preparacion. - Google Patents

Capsula para administracion oral que comprende n-terc-butil-3-[(5-metil-2-{[4-(2-pirrolidin-1-iletoxi)fenil]amino}pirimidin-4-il)amino]bencenosulfonamida, una celulosa microcristalina y estearil fumarato de sodio; forma de dosificacion unitaria; metodo para tratar mielofibrosis; metodo de preparacion; y articulo de preparacion.

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Publication number
CL2013001252A1
CL2013001252A1 CL2013001252A CL2013001252A CL2013001252A1 CL 2013001252 A1 CL2013001252 A1 CL 2013001252A1 CL 2013001252 A CL2013001252 A CL 2013001252A CL 2013001252 A CL2013001252 A CL 2013001252A CL 2013001252 A1 CL2013001252 A1 CL 2013001252A1
Authority
CL
Chile
Prior art keywords
amino
preparation
ylethoxy
benzenesulfonamide
pyrrolidin
Prior art date
Application number
CL2013001252A
Other languages
English (en)
Spanish (es)
Inventor
Arvind Jayan
Janice Cacace
Ayalew Tefferi
Original Assignee
Targegen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46024747&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2013001252(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Targegen Inc filed Critical Targegen Inc
Publication of CL2013001252A1 publication Critical patent/CL2013001252A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CL2013001252A 2010-11-07 2013-05-06 Capsula para administracion oral que comprende n-terc-butil-3-[(5-metil-2-{[4-(2-pirrolidin-1-iletoxi)fenil]amino}pirimidin-4-il)amino]bencenosulfonamida, una celulosa microcristalina y estearil fumarato de sodio; forma de dosificacion unitaria; metodo para tratar mielofibrosis; metodo de preparacion; y articulo de preparacion. CL2013001252A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41092410P 2010-11-07 2010-11-07

Publications (1)

Publication Number Publication Date
CL2013001252A1 true CL2013001252A1 (es) 2014-03-28

Family

ID=46024747

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013001252A CL2013001252A1 (es) 2010-11-07 2013-05-06 Capsula para administracion oral que comprende n-terc-butil-3-[(5-metil-2-{[4-(2-pirrolidin-1-iletoxi)fenil]amino}pirimidin-4-il)amino]bencenosulfonamida, una celulosa microcristalina y estearil fumarato de sodio; forma de dosificacion unitaria; metodo para tratar mielofibrosis; metodo de preparacion; y articulo de preparacion.

Country Status (36)

Country Link
US (5) US20130252988A1 (https=)
EP (2) EP2635282B1 (https=)
JP (1) JP6133211B2 (https=)
KR (4) KR101940979B1 (https=)
CN (2) CN103282036B (https=)
AU (2) AU2010363329A1 (https=)
BR (1) BR112013011184A2 (https=)
CA (2) CA2816957A1 (https=)
CL (1) CL2013001252A1 (https=)
CO (1) CO6801724A2 (https=)
DK (1) DK2635282T3 (https=)
DO (1) DOP2013000097A (https=)
EC (1) ECSP13012658A (https=)
ES (1) ES2930650T3 (https=)
HR (1) HRP20221269T1 (https=)
HU (1) HUE060254T2 (https=)
IL (1) IL226101A (https=)
LT (1) LT2635282T (https=)
MA (1) MA34723B1 (https=)
MX (2) MX360246B (https=)
MY (1) MY161164A (https=)
NI (1) NI201300038A (https=)
NZ (1) NZ611363A (https=)
PE (1) PE20140389A1 (https=)
PH (1) PH12013500924A1 (https=)
PL (1) PL2635282T3 (https=)
PT (1) PT2635282T (https=)
RS (1) RS63996B1 (https=)
RU (1) RU2616262C2 (https=)
SG (1) SG190134A1 (https=)
SI (1) SI2635282T1 (https=)
SM (1) SMT202200453T1 (https=)
TW (1) TWI531389B (https=)
UA (1) UA114076C2 (https=)
WO (2) WO2012060847A1 (https=)
ZA (1) ZA201303423B (https=)

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WO2013059548A1 (en) * 2011-10-19 2013-04-25 Sanofi Compositions and methods for treating cancer using jak2 inhibitor
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CN104771761A (zh) * 2015-03-19 2015-07-15 深圳国源国药有限公司 一种创新药用辅料硅化微晶纤维素及其制备方法
WO2017018385A1 (ja) * 2015-07-24 2017-02-02 公立大学法人名古屋市立大学 骨髄線維症の状態の診断を補助する方法、予後の予測を補助する方法、及び治療効果のモニター方法、並びにそれらの方法に用いるマーカー及び装置
CN105919955A (zh) * 2016-06-13 2016-09-07 佛山市腾瑞医药科技有限公司 一种鲁索利替尼制剂及其应用
MA45811A (fr) 2016-07-27 2019-06-05 Acceleron Pharma Inc Méthodes et compositions de traitement de maladie.
CN111892543A (zh) * 2018-01-16 2020-11-06 深圳市塔吉瑞生物医药有限公司 用于抑制激酶活性的二苯氨基嘧啶类化合物
BR112021005518A2 (pt) * 2018-09-25 2021-06-29 Impact Biomedicines, Inc. métodos para tratar distúrbios mieloproliferativos
KR20250134004A (ko) * 2018-09-25 2025-09-09 임팩트 바이오메디신스, 인코포레이티드 골수증식성 장애를 치료하는 방법
FR3092581A1 (fr) * 2019-02-12 2020-08-14 Impact Biomedicines, Inc Formes cristallines d'un inhibiteur de jak2
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KR20220119024A (ko) * 2019-12-20 2022-08-26 인터벳 인터내셔널 비.브이. 피라졸 제약 조성물
WO2021207051A1 (en) * 2020-04-06 2021-10-14 Bristol-Myers Squibb Company Methods of treating acute respiratory disorders
KR20230012539A (ko) 2020-05-13 2023-01-26 디스크 메디슨, 인크. 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
US20240058336A1 (en) 2020-12-16 2024-02-22 Impact Biomedicines, Inc. Dosing of fedratinib
MX2023009858A (es) 2021-02-25 2023-09-12 Impact Biomedicines Inc Uso de inhibidores de proteina de bromodominio y motivo extraterminal (bet) solo o en combinacion con fedratinib o ruxolitinib como tratamiento para una malignidad hematologica tal como la mielofibrosis.
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