CH691808A5 - (-)-(3R)-3-Methyl-4-{4-[4-(4-pyridyl)piperazin-1-y1]phenoxy}buttersäure als Inhibitor der zellulären Adhäsion. - Google Patents

(-)-(3R)-3-Methyl-4-{4-[4-(4-pyridyl)piperazin-1-y1]phenoxy}buttersäure als Inhibitor der zellulären Adhäsion. Download PDF

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Publication number
CH691808A5
CH691808A5 CH00224/97A CH22497A CH691808A5 CH 691808 A5 CH691808 A5 CH 691808A5 CH 00224/97 A CH00224/97 A CH 00224/97A CH 22497 A CH22497 A CH 22497A CH 691808 A5 CH691808 A5 CH 691808A5
Authority
CH
Switzerland
Prior art keywords
pharmaceutically acceptable
optically active
active compound
compound
ester
Prior art date
Application number
CH00224/97A
Other languages
German (de)
English (en)
Inventor
Stuart Dennett Mills
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CH691808A5 publication Critical patent/CH691808A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH00224/97A 1995-06-01 1996-05-28 (-)-(3R)-3-Methyl-4-{4-[4-(4-pyridyl)piperazin-1-y1]phenoxy}buttersäure als Inhibitor der zellulären Adhäsion. CH691808A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative

Publications (1)

Publication Number Publication Date
CH691808A5 true CH691808A5 (de) 2001-10-31

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
CH00224/97A CH691808A5 (de) 1995-06-01 1996-05-28 (-)-(3R)-3-Methyl-4-{4-[4-(4-pyridyl)piperazin-1-y1]phenoxy}buttersäure als Inhibitor der zellulären Adhäsion.

Country Status (31)

Country Link
EP (1) EP0796247A1 (da)
JP (1) JP2885941B2 (da)
KR (1) KR100245957B1 (da)
AT (1) AT406675B (da)
AU (1) AU710105B2 (da)
BE (1) BE1009520A5 (da)
BR (1) BR9606409A (da)
CA (1) CA2194397A1 (da)
CH (1) CH691808A5 (da)
CZ (1) CZ26997A3 (da)
DE (1) DE19680509T1 (da)
DK (1) DK10697A (da)
ES (1) ES2137886B1 (da)
FI (1) FI970393A (da)
GB (1) GB2304340B (da)
GR (1) GR1002702B (da)
HU (1) HUP9700274A3 (da)
IE (1) IE960405A1 (da)
IL (1) IL118477A0 (da)
IT (1) IT1290839B1 (da)
LU (1) LU90008B1 (da)
MC (1) MC2418A1 (da)
MX (1) MX9700379A (da)
NL (1) NL1003243C2 (da)
NO (1) NO307460B1 (da)
NZ (1) NZ308597A (da)
PL (1) PL318440A1 (da)
SE (1) SE510812C2 (da)
SK (1) SK13097A3 (da)
TR (1) TR199700020T1 (da)
WO (1) WO1996038416A1 (da)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
DE69411900T2 (de) * 1993-03-29 1998-12-10 Zeneca Ltd., London Heterozyklische derivate als plätchenaggregationsinhibitoren
ZW4194A1 (en) * 1993-03-29 1994-12-21 Zeneca Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
MC2418A1 (fr) 1997-05-23
NO970437D0 (no) 1997-01-31
FI970393A0 (fi) 1997-01-30
BR9606409A (pt) 1997-09-30
TR199700020T1 (tr) 1997-04-22
HUP9700274A3 (en) 2000-02-28
NO307460B1 (no) 2000-04-10
HU9700274D0 (en) 1997-04-28
GR1002702B (el) 1997-05-22
FI970393A (fi) 1997-01-30
ITMI961113A0 (it) 1996-05-31
DE19680509T1 (de) 1997-12-04
NO970437L (no) 1997-02-20
LU90008B1 (fr) 1997-04-16
JP2885941B2 (ja) 1999-04-26
ES2137886B1 (es) 2000-08-16
AU5827296A (en) 1996-12-18
MX9700379A (es) 1997-04-30
AU710105B2 (en) 1999-09-16
ATA900596A (de) 1999-12-15
SE9700203D0 (sv) 1997-01-24
NZ308597A (en) 1998-11-25
SE9700203L (sv) 1997-01-24
SK13097A3 (en) 1997-08-06
ITMI961113A1 (it) 1997-12-01
PL318440A1 (en) 1997-06-09
GB2304340A (en) 1997-03-19
KR100245957B1 (ko) 2000-04-01
WO1996038416A1 (en) 1996-12-05
HUP9700274A2 (hu) 1999-06-28
IE960405A1 (en) 1996-12-11
GB9627127D0 (en) 1997-02-19
IL118477A0 (en) 1996-09-12
CZ26997A3 (en) 1997-08-13
GB2304340B (en) 1998-07-29
JPH09512836A (ja) 1997-12-22
SE510812C2 (sv) 1999-06-28
BE1009520A5 (fr) 1997-04-01
EP0796247A1 (en) 1997-09-24
NL1003243C2 (nl) 1996-12-04
KR970704689A (ko) 1997-09-06
DK10697A (da) 1997-04-01
ES2137886A1 (es) 1999-12-16
CA2194397A1 (en) 1996-12-05
IT1290839B1 (it) 1998-12-14
AT406675B (de) 2000-07-25

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Owner name: ZENECA LIMITED TRANSFER- ASTRAZENECA AB

PL Patent ceased