NL1003243C2 - (-)-(3R)-3-methyl-4-{4-£4-(4-pyridyl)piperazine-1-yl|-fenoxy}boterzuur. - Google Patents

(-)-(3R)-3-methyl-4-{4-£4-(4-pyridyl)piperazine-1-yl|-fenoxy}boterzuur.

Info

Publication number
NL1003243C2
NL1003243C2 NL1003243A NL1003243A NL1003243C2 NL 1003243 C2 NL1003243 C2 NL 1003243C2 NL 1003243 A NL1003243 A NL 1003243A NL 1003243 A NL1003243 A NL 1003243A NL 1003243 C2 NL1003243 C2 NL 1003243C2
Authority
NL
Netherlands
Prior art keywords
piperazin
phenoxy
pyridyl
methyl
butyric acid
Prior art date
Application number
NL1003243A
Other languages
English (en)
Inventor
Stuart Dennett Mills
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of NL1003243C2 publication Critical patent/NL1003243C2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL1003243A 1995-06-01 1996-05-31 (-)-(3R)-3-methyl-4-{4-£4-(4-pyridyl)piperazine-1-yl|-fenoxy}boterzuur. NL1003243C2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative

Publications (1)

Publication Number Publication Date
NL1003243C2 true NL1003243C2 (nl) 1996-12-04

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
NL1003243A NL1003243C2 (nl) 1995-06-01 1996-05-31 (-)-(3R)-3-methyl-4-{4-£4-(4-pyridyl)piperazine-1-yl|-fenoxy}boterzuur.

Country Status (31)

Country Link
EP (1) EP0796247A1 (nl)
JP (1) JP2885941B2 (nl)
KR (1) KR100245957B1 (nl)
AT (1) AT406675B (nl)
AU (1) AU710105B2 (nl)
BE (1) BE1009520A5 (nl)
BR (1) BR9606409A (nl)
CA (1) CA2194397A1 (nl)
CH (1) CH691808A5 (nl)
CZ (1) CZ26997A3 (nl)
DE (1) DE19680509T1 (nl)
DK (1) DK10697A (nl)
ES (1) ES2137886B1 (nl)
FI (1) FI970393A (nl)
GB (1) GB2304340B (nl)
GR (1) GR1002702B (nl)
HU (1) HUP9700274A3 (nl)
IE (1) IE960405A1 (nl)
IL (1) IL118477A0 (nl)
IT (1) IT1290839B1 (nl)
LU (1) LU90008B1 (nl)
MC (1) MC2418A1 (nl)
MX (1) MX9700379A (nl)
NL (1) NL1003243C2 (nl)
NO (1) NO307460B1 (nl)
NZ (1) NZ308597A (nl)
PL (1) PL318440A1 (nl)
SE (1) SE510812C2 (nl)
SK (1) SK13097A3 (nl)
TR (1) TR199700020T1 (nl)
WO (1) WO1996038416A1 (nl)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022834A1 (en) * 1993-03-29 1994-10-13 Zeneca Limited Heterocyclic derivatives as platelet aggregation inhibitors
WO1994022835A2 (en) * 1993-03-29 1994-10-13 Zeneca Limited Heterocyclic compounds as platelet aggregation inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022834A1 (en) * 1993-03-29 1994-10-13 Zeneca Limited Heterocyclic derivatives as platelet aggregation inhibitors
WO1994022835A2 (en) * 1993-03-29 1994-10-13 Zeneca Limited Heterocyclic compounds as platelet aggregation inhibitors

Also Published As

Publication number Publication date
MC2418A1 (fr) 1997-05-23
NO970437D0 (no) 1997-01-31
FI970393A0 (fi) 1997-01-30
BR9606409A (pt) 1997-09-30
TR199700020T1 (tr) 1997-04-22
HUP9700274A3 (en) 2000-02-28
NO307460B1 (no) 2000-04-10
HU9700274D0 (en) 1997-04-28
GR1002702B (el) 1997-05-22
FI970393A (fi) 1997-01-30
ITMI961113A0 (it) 1996-05-31
DE19680509T1 (de) 1997-12-04
NO970437L (no) 1997-02-20
LU90008B1 (fr) 1997-04-16
JP2885941B2 (ja) 1999-04-26
ES2137886B1 (es) 2000-08-16
AU5827296A (en) 1996-12-18
MX9700379A (es) 1997-04-30
AU710105B2 (en) 1999-09-16
ATA900596A (de) 1999-12-15
CH691808A5 (de) 2001-10-31
SE9700203D0 (sv) 1997-01-24
NZ308597A (en) 1998-11-25
SE9700203L (sv) 1997-01-24
SK13097A3 (en) 1997-08-06
ITMI961113A1 (it) 1997-12-01
PL318440A1 (en) 1997-06-09
GB2304340A (en) 1997-03-19
KR100245957B1 (ko) 2000-04-01
WO1996038416A1 (en) 1996-12-05
HUP9700274A2 (hu) 1999-06-28
IE960405A1 (en) 1996-12-11
GB9627127D0 (en) 1997-02-19
IL118477A0 (en) 1996-09-12
CZ26997A3 (en) 1997-08-13
GB2304340B (en) 1998-07-29
JPH09512836A (ja) 1997-12-22
SE510812C2 (sv) 1999-06-28
BE1009520A5 (fr) 1997-04-01
EP0796247A1 (en) 1997-09-24
KR970704689A (ko) 1997-09-06
DK10697A (da) 1997-04-01
ES2137886A1 (es) 1999-12-16
CA2194397A1 (en) 1996-12-05
IT1290839B1 (it) 1998-12-14
AT406675B (de) 2000-07-25

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Legal Events

Date Code Title Description
PD2B A search report has been drawn up
VD1 Lapsed due to non-payment of the annual fee

Effective date: 20041201