GB9627127D0 - Acid as cellular adhesion inhibitor - Google Patents

Acid as cellular adhesion inhibitor

Info

Publication number
GB9627127D0
GB9627127D0 GBGB9627127.5A GB9627127A GB9627127D0 GB 9627127 D0 GB9627127 D0 GB 9627127D0 GB 9627127 A GB9627127 A GB 9627127A GB 9627127 D0 GB9627127 D0 GB 9627127D0
Authority
GB
United Kingdom
Prior art keywords
acid
cellular adhesion
adhesion inhibitor
inhibitor
cellular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB9627127.5A
Other versions
GB2304340A (en
GB2304340B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of GB9627127D0 publication Critical patent/GB9627127D0/en
Publication of GB2304340A publication Critical patent/GB2304340A/en
Application granted granted Critical
Publication of GB2304340B publication Critical patent/GB2304340B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB9627127A 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor Expired - Fee Related GB2304340B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative
PCT/GB1996/001260 WO1996038416A1 (en) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Publications (3)

Publication Number Publication Date
GB9627127D0 true GB9627127D0 (en) 1997-02-19
GB2304340A GB2304340A (en) 1997-03-19
GB2304340B GB2304340B (en) 1998-07-29

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9627127A Expired - Fee Related GB2304340B (en) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Country Status (31)

Country Link
EP (1) EP0796247A1 (en)
JP (1) JP2885941B2 (en)
KR (1) KR100245957B1 (en)
AT (1) AT406675B (en)
AU (1) AU710105B2 (en)
BE (1) BE1009520A5 (en)
BR (1) BR9606409A (en)
CA (1) CA2194397A1 (en)
CH (1) CH691808A5 (en)
CZ (1) CZ26997A3 (en)
DE (1) DE19680509T1 (en)
DK (1) DK10697A (en)
ES (1) ES2137886B1 (en)
FI (1) FI970393A (en)
GB (1) GB2304340B (en)
GR (1) GR1002702B (en)
HU (1) HUP9700274A3 (en)
IE (1) IE960405A1 (en)
IL (1) IL118477A0 (en)
IT (1) IT1290839B1 (en)
LU (1) LU90008B1 (en)
MC (1) MC2418A1 (en)
MX (1) MX9700379A (en)
NL (1) NL1003243C2 (en)
NO (1) NO307460B1 (en)
NZ (1) NZ308597A (en)
PL (1) PL318440A1 (en)
SE (1) SE510812C2 (en)
SK (1) SK13097A3 (en)
TR (1) TR199700020T1 (en)
WO (1) WO1996038416A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
DE69411900T2 (en) * 1993-03-29 1998-12-10 Zeneca Ltd., London HETEROCYCLIC DERIVATIVES AS PLATE AGGREGATION INHIBITORS
ZW4194A1 (en) * 1993-03-29 1994-12-21 Zeneca Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
MC2418A1 (en) 1997-05-23
NO970437D0 (en) 1997-01-31
FI970393A0 (en) 1997-01-30
BR9606409A (en) 1997-09-30
TR199700020T1 (en) 1997-04-22
HUP9700274A3 (en) 2000-02-28
NO307460B1 (en) 2000-04-10
HU9700274D0 (en) 1997-04-28
GR1002702B (en) 1997-05-22
FI970393A (en) 1997-01-30
ITMI961113A0 (en) 1996-05-31
DE19680509T1 (en) 1997-12-04
NO970437L (en) 1997-02-20
LU90008B1 (en) 1997-04-16
JP2885941B2 (en) 1999-04-26
ES2137886B1 (en) 2000-08-16
AU5827296A (en) 1996-12-18
MX9700379A (en) 1997-04-30
AU710105B2 (en) 1999-09-16
ATA900596A (en) 1999-12-15
CH691808A5 (en) 2001-10-31
SE9700203D0 (en) 1997-01-24
NZ308597A (en) 1998-11-25
SE9700203L (en) 1997-01-24
SK13097A3 (en) 1997-08-06
ITMI961113A1 (en) 1997-12-01
PL318440A1 (en) 1997-06-09
GB2304340A (en) 1997-03-19
KR100245957B1 (en) 2000-04-01
WO1996038416A1 (en) 1996-12-05
HUP9700274A2 (en) 1999-06-28
IE960405A1 (en) 1996-12-11
IL118477A0 (en) 1996-09-12
CZ26997A3 (en) 1997-08-13
GB2304340B (en) 1998-07-29
JPH09512836A (en) 1997-12-22
SE510812C2 (en) 1999-06-28
BE1009520A5 (en) 1997-04-01
EP0796247A1 (en) 1997-09-24
NL1003243C2 (en) 1996-12-04
KR970704689A (en) 1997-09-06
DK10697A (en) 1997-04-01
ES2137886A1 (en) 1999-12-16
CA2194397A1 (en) 1996-12-05
IT1290839B1 (en) 1998-12-14
AT406675B (en) 2000-07-25

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee